Matches 1 - 50 out of 222 1 2 3 4 5 >


Match Document Document Title
9023850 Nematocidal sulfonamides  
Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Z is O or S;A1, A2, A3 and A4 are independently N or CR1, provided that only one of A1, A2, A3 and A4 is N; andR1, R2, R3...
9000045 CETP activity inhibitors  
The invention provides a compound that is a CETP activity inhibitor. The compound can increase HDL and at the same time decrease LDL through selective inhibition of CETP activity. the invention...
8951999 Compounds  
This invention relates to compounds of formula I, their use as inhibitors of the microsomal prostaglandin E2 synthase-1 (mPGES-1), pharmaceutical compositions containing them, and their use as...
8952031 Amino- and amido-aminotetralin derivatives and related compounds as mu opioid receptor antagonists  
The invention provides amino- and amido-aminotetralin compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, and n are defined in the specification, or a pharmaceutically-acceptable salt...
RE45314 N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors  
The invention relates to N-hydroxysulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of...
8906955 Use of adrenergic beta-3-receptor agonists in anti-aging  
A method for treating an aging-related disease is disclosed comprising administering to a subject a pharmaceutical composition comprising an adrenergic beta-3-receptor agonist.
8829052 Derivatives of N-(arylamino)sulfonamides as inhibitors of MEK  
This invention concerns N-(2-arylamino)aryl sulfonamides, which are inhibitors of MEK and are useful in treatment of cancer and other hyperproliferative diseases.
8808742 Compositions and methods for preparing and using same  
This invention relates to compositions, methods for preparing the compositions and methods for treating or preventing diseases, comprising administering the compositions.
8778897 Method of treatment using α-1-adrenergic agonist compounds  
Methods for treating or preventing cardiomyopathy in a subject by administering an α1 adrenergic receptor agonist, wherein the treatment does not result in increased blood pressure are provided.
8772343 Chemical compounds  
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More...
8686043 Heterocyclic sulfonamides, uses and pharmaceutical compositions thereof  
The invention is directed to a class of compounds, including the pharmaceutically acceptable salts of the compounds, having the structure of formula I: as defined in the specification. The...
8673953 Compositions and methods for treating purpura  
Embodiments of the present invention are directed to compositions and methods for the treatment of purpura. Preferred compositions comprise an α adrenergic receptor agonist selected from selective...
8664247 Acyclic organonitro compounds for use in treating cancer  
The present invention provides acyclic, geminal-dinitro organic compounds, methods of synthesizing the compounds, pharmaceutical compositions, therapeutic methods, and medical kits for treating...
8653141 HIV protease inhibiting compounds  
A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
8648116 Derivatives of N-(arylamino) sulfonamides including polymorphs as inhibitors of MEK as well as compositions, methods of use and methods for preparing the same  
This invention concerns N-(2-arylamino) aryl sulfonamide compounds which are inhibitors of MEK including crystalline polymorphic forms which exhibit a specific powder x-ray diffraction profile...
8609076 Use of particular polyols for preventing the hair from breaking, composition comprising them and cosmetic hair treatment process  
The present invention relates to the use of polyols of formula (I): or a salt thereof, for preventing the hair from breaking. The invention also relates to a cosmetic composition comprising at...
8569378 p27 protein inducer  
The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient:...
8536229 Acetylene derivatives having MGluR 5 antagonistic activity  
The invention provides compounds of formula I wherein n, A, R, R′, R″, RO, X and Y are as defined in the description, and their preparation. The compounds of formula I are useful as pharmaceuticals.
8524778 Biphenyl-4-yl-sulfonic acid arylamides and their use as therapeutic agents  
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl sulfonamides and related compounds (collectively referred to herein as ‘BPSAAA...
8518998 Use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides in the treatment of pain  
The present invention relates to the use of sulfonyl-substituted 2-sulfonylaminobenzoic acid N-phenylamides of the formula I, wherein A and R1 to R6 have the meanings indicated in the claims, for...
8518860 Herbicidal suspension  
A herbicidal suspension comprising (1) a sulfonylurea compound or its salt as a herbicidal component, (2) at least one surfactant selected from the group consisting of an alkoxylated sorbitol...
8501812 Therapeutic methods for type I diabetes  
The invention relates to the treatment and prevention of type I diabetes. More specifically, the invention relates to compounds that treat or prevent the body's immune system from destroying...
8461209 Malonic acid sulfonamide derivative and pharmaceutical use thereof  
The invention provides a sulfonyl malonamide derivative, or a pharmacologically acceptable salt thereof or a solvate thereof, that has therapeutic and/or preventive effects(s) on various diseases...
8410150 Inhibitors of carnitine palmitoyltransferase and treating cancer  
A CPT inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition...
8404747 Compositions and methods for modulating interaction between polypeptides  
The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one...
8399496 Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections  
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae,...
8389500 Fused heterocyclic compounds as ion channel modulators  
The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In...
8367645 Compositions and methods for treating hyperproliferative diseases  
The invention relates to a composition that includes a first agent selected including an agent that possesses anti-inflammatory activity or acetaminophen, phenacetin, tramadol and the like; a...
8329755 Methods for treating retroviral infections  
The present invention provides compositions for treating an HIV infection comprising administering a compound according to formula I where Ar, R1-R5, R11c and X1 are as defined herein with at...
8324178 Method of treatment using alpha-1-adrenergic agonist compounds  
Methods for treating or preventing cardiomyopathy in a subject by administering an α1 adrenergic receptor agonist, wherein the treatment does not result in increased blood pressure are provided.
RE43802 α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors  
α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
8309607 Rapid release irbesartan-containing pharmaceutical composition  
The present invention relates to an irbesartan-containing pharmaceutical composition, in particular a tablet thereof, which comprises the active ingredient, a disintegrant with at least one...
8293795 Preparation of concentrated aqueous bromine solutions and biocidal applications thereof  
A process of producing a concentrated liquid biocide formulation is described. Mixed together are (a) bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at...
8252842 Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof  
Disclosed herein, in certain embodiments, is a crystalline polymorph form A of N—(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxy phenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide...
8247451 ADAM10 and its uses related to infection  
The present invention relates to a protein, ADAM10, ADAM10 nucleic acid sequences and ADAM10 proteins encoded by these sequences that are involved in infection by one or more pathogen such as a...
8207167 Aryl-phenyl-sulfonamide-phenylene compounds and their use  
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-phenyl-sulfonamido-phenylene compounds of the following formula (I)...
8148422 Sulfonamides as TRPM8 modulators  
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) and Formula (II)...
8138218 Growth hormone secretagogues  
A family of peptides and peptidomimetic compounds useful as GHS analogs according to either formula (I) or (II) as depicted below: or a pharmaceutically acceptable salts thereof, wherein the...
8128958 Sustained release pharmaceutical composition  
The present invention provides a sustained-release pharmaceutical composition, characterized in that, there are contained tamsulosin or a pharmaceutically acceptable salt thereof and a carrier for...
8114898 Compositions and methods for treating purpura  
Embodiments of the present invention are directed to compositions and methods for the treatment of purpura. Preferred compositions comprise an α adrenergic receptor agonist selected from selective...
8106033 Composition and methods for the treatment of proliferative diseases  
Methods and compositions are provided for treating proliferative disorders, wherein the composition comprises at least one compound according to Formula I: wherein R1 is selected from the group...
8088827 Use of irbesartan for the preparation of medicinal products that are useful for treating pulmonary hypertension  
The present invention relates to the use of irbesartan for the preparation of medicinal products that are useful for preventing or treating pulmonary arterial hypertension or pulmonary hypertension.
8053449 Method for inhibiting AGE complex formation  
Various methods of administering medication(s) that inhibit the nonenzymatic formation of glycation and dehydration condensation complexes known as advanced glycation end-products (AGEs) or...
8048435 Preparation of concentrated aqueous bromine solutions and biocidal applications thereof  
A process of producing a concentrated liquid biocide formulation is described. Mixed together are (a) bromine and (b) an aqueous solution of alkali metal salt of sulfamic acid having a pH of at...
RE42889 α- and β- amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors  
α- and β-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
8048896 Methods for inhibiting and breaking AGE complex formation  
Various methods of administering medication(s) that inhibit the nonenzymatic formation of glycation and dehydration condensation complexes known as advanced glycation end-products (AGEs) or...
8030335 Use of liver X receptor agonists  
The present invention generally relates to a novel therapeutical use of liver X receptor (LXR) agonsits. More specifically, the present invention relates to the use of LXR agonist for the...
7981839 Herbicidal suspension  
A herbicidal suspension comprising (1) a sulfonylurea compound or its salt as a herbicidal component, (2) at least one surfactant selected from the group consisting of an alkoxylated sorbitol...
7981401 Diuretic aerosols and methods of making and using them  
Described herein are diuretic condensation aerosols and methods of making and using them. Kits for delivering a condensation aerosol are also described. The diuretic aerosols typically comprise...
7973078 Sulfonamide compound or salt thereof  
A compound that can be used as an agent for treating a disease associated with an EP1 receptor, in particular a lower urinary tract symptom. It was confirmed that a sulfonamide compound having an...

Matches 1 - 50 out of 222 1 2 3 4 5 >