|
Match
|
Document |
Document Title |
|
|
7622612 |
Tricyclic derivatives and their use
The present invention relates to tricyclic colchicine derivatives represented by the formulas (I) or (II), pharmaceutically acceptable salts thereof, and a method for providing an...
|
|
|
7598416 |
4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for...
|
|
|
7579503 |
BIS (thio-hydrazide amide) salts for treatment of cancers
Disclosed are bis(thio-hydrazide amide) disalts, which are represented by Structural Formula (I):
Y is a covalent bond or a substituted or unsubstituted straight chained hydrocarbyl group. R 1...
|
|
|
7476683 |
Glycinamide derivatives as raf-kinase inhibitors
The present invention relates to glycinamide derivatives of formula (I), the use of the compounds of formula (I) as inhibitors of raf-kinase, the use of the compounds of formula (I) for the...
|
|
|
7425649 |
4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for...
|
|
|
7288262 |
Composition comprising a cyclohexane-based compound, compound and use of said compound to structure a composition
Compositions, in particular cosmetic compositions, comprising a cyclohexane-based compound defined by formula (I):
wherein:
R, which may be identical or different, are each chosen from...
|
|
|
7105545 |
N-p-propargyloxyphenethyl-thioacetic acid amides
The invention relates to N-propargyloxy-phenethyl thioacetic acid amide derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R 1 is...
|
|
|
7037940 |
Taxol enhancer compounds
Disclosed is a compound represented by the Structural Formula (I):
Y is a covalent bond, a phenylene group or a substituted or unsubstituted straight chained hydrocarbyl group. In...
|
|
|
RE38761 |
Styryl compounds which inhibit EGF receptor protein tyrosine kinase
A method of inhibiting cell proliferation in a patient suffering from such disorder comprising administering to said patient an effective amount of a composition comprising, in admixture with a...
|
|
|
6740681 |
Pharmaceutical compositions comprising thiram
Thiram (tetramethyliuram disulfide) is shown to inhibit angiogenesis and/or inflammation and to be useful in the treatment of angiogenesis-dependent disorders, including neoplasms, and in the...
|
|
|
6716881 |
Carbanilides used as pesticides
The present invention provides carbanilides of formula (I), wherein A, Q, R, X, Z and m are as defined herein. A plurality of processes for preparing these compounds is provided, along with...
|
|
|
6710086 |
Protected forms of pharmacologically active agents and uses therefor
In accordance with the present invention, there are provided conjugates of dithiocarbamates “DC”) and pharmacologically active agents (e.g., NSAIDs). Invention conjugates provide a new class of...
|
|
|
6656971 |
Trisubstituted carbocyclic cyclophilin binding compounds and their use
The present invention relates to novel, non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilin proteins, and to pharmaceutical compositions comprising one...
|
|
|
6596770 |
Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor
The present invention provides a novel dithiocarbamamte disulfide dimer useful in various therapeutic treatments, either alone or in combination with other active agents. In one method, the...
|
|
|
6573284 |
Method of treating melanoma
Novel pro-drugs and assay reagents are provided which are useful as therapeutic agents especially for delivery and targetting therapeutically active agents to melanoma cells. The pro-drugs and...
|
|
|
6509379 |
Phenylacetic acid derivatives, process and intermediate products for their preparation, and their use as fungicides and pesticides
Phenylacetic acid derivatives of the formula I where the variables are as disclosed herein, their salts, processes and intermediates for their preparation, and their use for controlling harmful...
|
|
|
6500416 |
Pesticide
There are described a flowable composition for controlling harmful insects and representatives of the order Acarina, comprising at least one pesticidally active compound, one or more signal...
|
|
|
6476076 |
Vanilloid analogues containing resinferatoxin pharmacophores as potent vanilloid receptor agonists and analgesics, compositions and uses thereof
The present invention is related to new vanilloid analogues containing resiniferatoxin pharmacophores, pharmaceutical compositions comprising such analogues, and their uses as vanilloid receptor...
|
|
|
RE37873 |
Phenylacetic acid derivatives, preparation thereof and intermediates therefor, and compositions containing them
Phenylacetic acid derivatives of the formula I
|
|
|
6458844 |
Diphenyl carbocyclic thioamide derivatives
It has been discovered that compounds of the formula: and the pharmaceutically acceptable salts and esters thereof wherein X and Y are as defined below, inhibit the binding of VCAM-1 to VLA-4...
|
|
|
6441043 |
Glyoxylic acid amides
The invention relates to novel glyoxylic acid amides, to a plurality of processes for their preparation and to their use for controlliing pests.
|
|
|
6420423 |
Pesticides
Compounds of the formula: in which n, q, A, X, G, Y, Z, R, R 2 , R 3 , R 4 , R 5 , R 7 and R 9 are as defined in claim 1 , and, where appropriate, E/Z isomers, E/Z isomer mixtures and/or...
|
|
|
6329428 |
Therapeutic drug for the treatment of micturition disorders
The present invention is drawn to a therapeutic drug for micturition disorders and diseases of the lower urinary tract system, containing an organic acid salt of...
|
|
|
6288110 |
Pharmaceutical compositions comprising disulfiram
Disulfiram (tetraethylthiuram disulfide) is shown to inhibit angiogenesis and to be useful in the treatment of angiogenesis-dependent disorders, including neoplasms, and to prevent cell...
|
|
|
6274627 |
Conjugates of dithiocarbamate disulfides with pharmacologically active agents and uses therefor
In accordance with the present invention, there are provided conjugates of physiologically compatible free radical scavengers (e.g., dithiocarbamate disulfides (DD)) and pharmacologically active...
|
|
|
6255326 |
Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic-or heteroatom-containing linking group
This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also...
|
|
|
6211240 |
O-benzyl oxime ether derivatives and their use as pesticides
Compounds of the formula I ##STR1## in which Y is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 alkoxy, OH, CN, NO 2 , Si(CH 3 ) 3 , CF 3 or halogen, Z is a group a) ##STR2## R 1 is hydrogen, C...
|
|
|
6207716 |
Non-steroidal ligands for the estrogen receptor
Novel non-steroidal ligands for the estrogen receptor which possess tissue-dependent estrogenic and antiestrogenic activity as well as methods for making the same and their applications in treating...
|
|
|
6177463 |
Oxime derivatives and their use as pesticides
The invention relates to new oxime derivatives, to a plurality of processes for their preparation, and to their use as pesticides.
|
|
|
6130251 |
Alkoximinoacetic acid amides
The invention relates to new alkoximinoacetic acid amides, a process for their preparation and their use as agents for combating pests.
|
|
|
6083987 |
Phenylenediamine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant
A phenylenediamine derivative or a salt thereof in accordance with the present invention is expressed by the following formula 1: ##STR1## wherein A represents a group expressed by --CO--, --CH 2 ...
|
|
|
6054476 |
Iminoacetic acid amides and their use as pest control agents
Iminoacetamides of the formula (I) ##STR1## in which A represents a single bond or optionally substituted alkylene, Q represents oxygen or sulphur, R 1 represents respectively optionally...
|
|
|
6020317 |
Glycerol derivative, device and pharmaceutical composition
The object of the invention is to provide a lipid device functionally equivalent to the so-called cationic liposome and of lesser toxicity and a lipid or the like as a component of the device. The...
|
|
|
5994383 |
Surfactant-based antimicrobial compositions and methods for using the same
Antimicrobial compositions and methods for preparing and using same are provided. The antimicrobial compositions are surfactant-based and contain certain benzalkonium chloride homologs. The...
|
|
|
5990171 |
Hydrazonoacetic acid amides and the use thereof as pesticides
The invention concerns hydrazonoacetic acid amides of general formula (I), a process for producing them, and the use of the said amides as pesticides. In the formula shown, the following meanings...
|
|
|
5985921 |
2-Phenyl-2-methoxyimino acetic acid esters
Compounds of the formula ##STR1## in which n, q, A, X, G, Y, Z, R, R 2 , R 3 , R 4 , R 5 , R 7 and R 9 are as defined in claim 1, and, where appropriate, E/Z isomers, E/Z isomer mixtures and/or...
|
|
|
5929118 |
Fluorobutenic acid hydrazides
The present invention relates to novel fluorobutenic acid hydrazides of the formula (I) ##STR1## in which Y represents CO, CS or SO 2 , R 1 represents hydrogen or halogen and R 2 ...
|
|
|
5914351 |
Anti-viral aromatic hydrazones
Compounds of the formula ##STR1## wherein Q is a hydrazone derivative; R 1 is hydrogen, halogen, alkyl or alkoxy; R 2 is hydrogen, halogen, alkyl, alkoxy, alkenoxy, alkynyloxy, halomethyl,...
|
|
|
5886045 |
Remedy for allergic diseases in the region of the nose
An anti-allergic pharmaceutical composition for nasal topical administration comprising an IgE antibody production inhibitor as an active ingredient, which is effective and safe in its nasal...
|
|
|
5877203 |
Treatment for atherosclerosis and other cardiovascular and inflammatory diseases
Dithiocarboxylates, and in particular, dithiocarbamates, block the induced expression of the endothelial cell surface adhesion molecule VCAM-1, and are therefor useful in the treatment of...
|
|
|
5849796 |
Ortho-substituted benzoil acid derivatives
Ortho-substituted benzoic acid derivatives of the formula I ##STR1## in which R 1 , R 2 and R 3 have the given meanings, and Q is guanidyl, and also their physiologically harmless salts, exhibit...
|
|
|
5847004 |
Method for in vivo reduction of nitric oxide levels and compositions useful therefor
In accordance with the present invention, there are provided methods for the in vivo reduction of nitric oxide levels in a mammalian subject. In contrast to the inhibitory approach described in the...
|
|
|
5824704 |
Anti-viral aromatic O-alkylated oximes, ethers and thioethers
Compounds of the formula ##STR1## These compounds are useful for inhibiting the growth or replication of retroviruses such as HIV.
|
|
|
5780512 |
Alkylated (hetero) cyclic compounds
The invention relates to a compounds selected from these of formula (I): ##STR1## in which: R 1 , R 2 , R 3 and A are as defined in the description, and a medicinal product containing the same...
|
|
|
5753256 |
Plaster for the treatment of nail mycoses
The invention relates to a plaster for the treatment of nail mycoses, which s characterized by an antimycotically active substance, clotrimazole and bifonazole being excluded.
|
|
|
5721276 |
Arylalkyl(thio)carboxamides
The invention relates to a compound selected from those of formula (I): ##STR1## in which A, B, X and R 1 are as defined in the description, and medicinal product containing the same useful for...
|
|
|
5670528 |
Thioamides and their use as crop protection agents
Thioamides of the formula I ##STR1## where A, B, R' are hydrogen, cyano, alkyl, alkoxy or halogen, X is CHCH 3 or N--OCH 3 , R 1 , R 2 - are hydrogen or alkyl, Y is a group...
|
|
|
5668180 |
Alkoxyaryl compounds
A compound selected from those of formula (I): ##STR1## in which A, R, Y, R 1 , R 2 and R 3 are as defined in the description, and a medicinal product containing the same useful for treating a...
|
|
|
5602119 |
Succinoylamino hydroxyethylamino sulfamic acid derivatives useful as retroviral protease inhibitors
Succinoylamino hydroxyethylamino sulfamic acid derivative compounds which are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
|
|
|
5591775 |
Trisubstituted naphthylalkylamides for disorders of the melatoninergic system
The invention relates to a compound selected from those of formula (I): ##STR1## in which R, R 1 , R 2 and R 3 are as defined herein for use in the treatment of a disorder of the melatoninergic...
|