|
Match
|
Document |
Document Title |
|
|
7601870 |
Substituted aniline derivatives
The present invention relates to aniline derivatives of the general formula I or salts thereof, described therein, and their use.
|
|
|
7560591 |
Benzamidine derivatives having anti-inflammatory and immunosuppressive activity
Compounds which can be represented by the general formula (I) indicated below:
and in which:
A is selected independently from the carboxamide group, the thiocarboxamide group, and the...
|
|
|
7544716 |
Tetrahydro-naphthalene derivatives as vanilloid receptor antagonists
This invention relates to tetrahydro-naphthalene derivatives of formula (I)
in which the variable groups are as defined in the specification and claims, and tautomeric and stereoisomeric forms...
|
|
|
7482487 |
Phenylaminoethanol derivatives as β2 receptor agonists
The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The...
|
|
|
7307071 |
RAF-MEK-ERK pathway inhibitors to treat cancer
Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia,...
|
|
|
RE39866 |
Nonpeptide insulin receptor agonists
Modulation of the activity of the insulin receptor, enhancement of glucose uptake by cells, and other effects significant in the control and management of diabetes are accomplished using compounds...
|
|
|
7262220 |
Urea- and urethane-substituted acylureas, process for their preparation and their use
The invention relates to urea- and urethane-substituted acylureas and to their physiologically tolerated salts and physiologically functional derivatives. In particular, the invention relates to...
|
|
|
7208528 |
Polyamine analogues as therapeutic and diagnostic agents
Novel inhibitors of polyamine transport having inhibition constants two orders of magnitude lower than those of known compounds are disclosed. These polyamine analogues are useful pharmaceutical...
|
|
|
7109243 |
Inhibitors of cathepsin S
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at...
|
|
|
7105567 |
3-substituted urea derivatives and medicinal use thereof
The present invention relates to a urea derivative of the formula (1)
wherein each symbol is as described in the specification, a pharmaceutically acceptable salt thereof and pharmaceutical use...
|
|
|
7049341 |
N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use
N-Benzoylureidocinnamic acid derivatives, processes for preparing them and their use The invention relates to N-benzoylureidocinnamic acid derivatives and to their physiologically tolerated salts...
|
|
|
7034056 |
Aryl and biaryl compounds having MCH modulatory activity
In one embodiment, this invention provides a novel class of compounds as antagonists of the MCH receptor, methods of preparing such compounds, pharmaceutical compositions containing one or more of...
|
|
|
7026357 |
Diphenylurea compounds
Compound of formula (I):
and medicinal products containing the same are useful as dual α 2 /5-HT 2c antagonist receptors.
|
|
|
6984647 |
Aminotetralin-derived urea modulators of vanilloid VR1 receptor
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are...
|
|
|
6982285 |
Control of parasites attached to skin of fish
A method of successfully controlling sea lice in commercial fish farming, in an efficient and environmentally friendly way, with the compounds named in claim 1 , preferably by injection, and a...
|
|
|
6924311 |
Methods for affecting various diseases utilizing LXR compounds
The present invention relates to methods for elevating high density lipoprotein (HDL) plasma levels, decreasing the absorption of dietary cholesterol in the intestine, decreasing the plasma level...
|
|
|
6852760 |
Compositions and methods for treatment for glucose metabolism disorders
Compositions and methods of using the same for the treatment of diabetes and other disorders of glucose metabolism are provided. Compositions may include an anti-diabetic agent and one or more of a...
|
|
|
6849617 |
Tissue factor antagonists and methods of use thereof
The invention includes pharmaceutically active compounds and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are...
|
|
|
6838472 |
Substituted urea retinoid agonists
The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention...
|
|
|
6822001 |
Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents
Combination therapies are provided for the treatment of proliferative disorders which use a pentafluorobenzenesulfonamide of formula I and an antineoplastic agent such as gemcitabine or paclitaxel.
|
|
|
6812250 |
Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which...
|
|
|
6699904 |
PPAR agonists
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and...
|
|
|
6699486 |
Treatment or prevention of photoaging and skin cancer
Disclosed herein are methods for the treatment or prevention of photoaging or skin cancer in a patient. These methods include administering a compound that inhibits a component of the kallikrein...
|
|
|
6696488 |
(Hydroxyethyl)ureas as inhibitors of alzheimer's β-amyloid production
Novel (hydroxyethyl)ureas are described. These compounds are effective inhibitors of certain aspartyl proteases, notably secretases involved in the enzymatic cleavage of amyloid precursor protein...
|
|
|
6696487 |
Fungicidal phenyl(thio)urea and phenyl(thio)carbamate derivatives
The invention relates to compounds of formula (I), and also to salts thereof, which have fungicidal activities: in which the various radicals and substituents are as defined in the description,...
|
|
|
6686394 |
Aryl-chloro-ethyl ureas
Described herein are novel 1-aryl-3-(2-chloroalkanylureas derivatives. These derivatives are useful anticaner agents having excellent specifilty towards cell targets and potent antineoplastic...
|
|
|
6624117 |
Heat sensitive recording material
A heat sensitive recording material, comprising a) at least one colour forming compound, and b) at least one developer of the formula wherein R 1 is unsubstituted or substituted phenyl,...
|
|
|
6608052 |
Compounds useful as anti-inflammatory agents
Disclosed are novel aromatic compounds of the formula(I) wherein G, E, W, Ar, X, Y and Z. The compounds are useful for treating diseases or pathological conditions involving inflammation such as...
|
|
|
6593362 |
Non-peptidic cyclophilin binding compounds and their use
This invention relates to pharmaceutical compositions and methods of using non-peptidic cyclophilin-binding compounds in medical conditions involving breakdown of mitochondrial energy metabolism...
|
|
|
6566304 |
Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture
The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a)...
|
|
|
6548539 |
Agents for regulation of colon cancer gene expression
Compounds of the general structure according to Formula (I) wherein R 1 is selected from alkyl, alkenyl, alkynyl, heteroalkyl, haloalkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl,...
|
|
|
6538031 |
Method of controlling sea lice infestation in fish
A method of successfully controlling sea lice in commercial fish farming, in an efficient and environmentally friendly way, with the compounds named in claim 1 , preferably by injection, and a...
|
|
|
6531499 |
Matrix metalloproteinase inhibitors and method of using same
Peptoid compounds of Formula I and Formula II are disclosed The compounds are useful in the treatment of matrix metalloproteinase-mediated disorders.
|
|
|
6506802 |
Disulfide derivatives useful for treating allergic diseases
Novel disulfide derivatives useful for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of...
|
|
|
6492419 |
Aqueous insecticidal pour-on formulation
A topically acceptable aqueous pour-on formulation adapted for localized external application to an animal, which format includes an effective amount of a water insoluble insect growth regulator...
|
|
|
6469067 |
Combinations
An active ingredient combination for the simultaneous control of ecto- and endoparasites, especially mites, ticks and nematodes, on productive livestock, domestic animals and pets, is described,...
|
|
|
6391917 |
Dialkyl ureas as calcitonin mimetics
Dialkyl urea compounds are described which act as calcitonin mimetics. These compounds are useful in the treatment of diseases which are associated with bone resorption. The calcitonin mimetics of...
|
|
|
6387906 |
2,4,4-trisubstituted-1,3-dioxolane antifungals
The present invention concerns novel compounds of formula a N-oxide form, a pharmaceutically acceptable acid addition salt or a stereochemically isomeric form thereof, wherein n is zero, 1, 2 or...
|
|
|
6362229 |
Inhibitors of multidrug transporters
The present invention relates generally to the fields of bacteriology and mycology. More particularly, the present invention provides novel inhibitors of multidrug transport proteins that may be...
|
|
|
6344476 |
Inhibition of p38 kinase activity by aryl ureas
This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases other than cancer and proteolytic enzyme mediated diseases other than cancer, and pharmaceutical...
|
|
|
6271268 |
Compositions and methods for decreasing sebum production
A method of treating diseases caused by sebaceous gland disorders, in humans and animals, which comprises administering to said humans and animals a composition comprising a sebaceous gland...
|
|
|
6248787 |
Guanylhydrazones and their use to treat inflammatory conditions
This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with...
|
|
|
6214881 |
IL-8 receptor antagonists
The present invention relates to the novel use of phenyl ureas in the treatment of disease states mediated by the chemokine, Interleukin-8 (I-8).
|
|
|
6197798 |
Amino-benzocycloalkane derivatives
Compounds of the formula I ##STR1## wherein R 2 --C, R 3 --C, R 4 --C or R 5 --C may be replaced by N; and wherein n is 1, 2 or 3; R 1 is aryl, cycloalkyl or heterocyclyl; R 2 , R...
|
|
|
6187799 |
Inhibition of raf kinase activity using aryl ureas
Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.
|
|
|
6147116 |
Polyaromatic antiviral compositions
The present invention relates to polyaromatic compounds having useful antiviral activity against viruses of the herpes family, to a composition containing them, and to a method of using them for...
|
|
|
6129782 |
Inhibition of bacterial growth
The invention provides a means of inhibiting bacterial growth particularly on a coated substrate. It comprises a method of forming a substantially dry powder coating containing a biocide, applying...
|
|
|
6103761 |
Agents acting at cholecystokinin receptors
The invention concerns a series of novel bis-urea derivatives, nonpeptides, which show good binding affinity for the CCK-B receptor. The compounds, compositions containing them, methods of...
|
|
|
6083986 |
Potassium channel inhibitors
Compounds useful as potassium channel inhibitors and especially useful for the treatment of cardiac arrhythmias and cell proliferative disorders are described.
|
|
|
6060484 |
Anti-viral method
|