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4871541 |
Insect repelling/killing composition and method of use thereof
A process for the preparation of insect repelling/killing film. The process involves forming a clathrate compound of fenitrothion with cyclodextrin or a starch decomposition product containing...
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4869904 |
Sustained release drug preparation
Now is provided a new sustained release drug preparation comprising such an inclusion complex of a medical compound with a hydrophobic cyclodextrin derivative, e.g. ethylated cyclodextrins, which...
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4870060 |
Derivatives of γ-cylodextrin
Novel derivatives of γ-cyclodextrin, their preparation and their use as complexants and solubilizers. Compositions containing the novel γ-cyclodextrin derivatives and method of preparing such...
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4849425 |
Readily absorbable pharmaceutical composition
A pharmaceutical composition comprises a benzoyl urea compound having the formula: ##STR1## wherein X is a nitro group, Y is a chlorine atom, Z 2 is a hydrogen atom, Z 1 is a halogen atom, and A...
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4847074 |
Whitening cosmetic
A whitening cosmetic comprises kojic acid and cyclodextrins in addition to cosmetic base materials. The kojic acid may be included in cyclodextrins before being incorporated into the cosmetic. The...
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4834985 |
Controlled release pharmaceutical composition
A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water...
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4831022 |
Inclusion compound of eicosapentaenoic acid and food product containing the same
A novel EPA/CD inclusion compound and a food product containing the same are disclosed. The undesirable odor of EPA is masked by including it into such EPA/CD inclusion compound. Gamma-CD is most...
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4793986 |
Macromolecular platinum antitumor compounds
A composition comprising a pharmaceutically acceptable polysaccharide carrier which has been chemically activated and then linked to platinum in either a +2 or +4 oxidation state through a...
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4791104 |
Dihydrobenzothiophene and thiochromane aminoalcohols
The invention is concerned with dihydrobenzothiophene and thiochromane derivatives of the generic formula ##STR1## The compounds show anti-hypertensive, platelet aggregation inhibiting,...
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4774232 |
Bile-substituting method of treatment for the promotion of fat digestion
The invention relates to a method of promoting the fat digestion and absorption, which comprises orally administering to an animal subject a partially methylated-β-cyclodextrin optionally together...
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4769242 |
Process for preparing insect-repellant and insecticidal article for breeding plants
A process for preparing an insect-repellent and insecticidal article for breeding plants including forming a clathrate compound consisting of an organophosphorus or a pyrethroid insecticide...
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4764604 |
Derivatives of gamma-cyclodextrin
This invention relates to γ-cyclodextrin ethers and mixed ethers wherein the ether substituents are C 1 -C 6 alkyl, hydroxy C 1 -C 6 alkyl, carboxy C 1 -C 6 alkyl or (C 1 -C 6 ...
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4732759 |
Bath preparations and method for producing the same
A bath preparations comprise a cyclodextrin clathrate compound of vitamin, saccharifying enzyme and other materials of baths. The vitamin may be selected from the group consisting of vitamin A,...
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4727064 |
Pharmaceutical preparations containing cyclodextrin derivatives
The invention comprises pharmaceutical preparations consisting generally of a drug with a substantially low water solubility and an amorphous, water-soluble cyclodextrin-based mixtures. In these...
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4725434 |
Process for the preparation of a free flowing, homogeneous, iodophor containing wound powder
A free flowing iodophor powder which can be used for the treatment of wounds and the like, is prepared by spraying a solution of the iodophor in an aqueous-alcoholic solvent having a boiling point...
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4722815 |
Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrin
A synthetic resin product contains various substances such as perfumes, insectifuges/insecticides, mold/mildew-proofing agents and anti-fungi agents which are inactivated by forming an inclusion...
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4707472 |
Cycloartenol ferulate/cyclodextrin complex
Cycloartenol ferulate/cyclodextrin complex is prepared by including cycloartenol ferulate, which is a component of γ-oryzanol and hardly soluble in water, with cyclodextrin to thereby elevate its...
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4703042 |
Orally active heparin salts containing multivalent cationic units
The invention provides novel orally active salts of the formula ##STR1## in which .circle. is the skeleton of a polyol, n is the number of OH's in the polyol (3 to 24); p is ≥3 and ≤n; r is...
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4696918 |
Solubilized platinum compound
The anti-cancer compound 1,1-cyclobutanedicarboxylatediammineplatinum(II) is rendered more water-soluble by formation of its inclusion compound with α-cyclodextrin.
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4687763 |
Composition and method for increasing levels or release of brain serotonin
A composition comprising tryptophan and melatonin with or without an insulin-releasing carbohydrate or melatonin and an insulin-releasing carbohydrate is administered to an animal in order to...
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4672112 |
β-Cyclodextrine complex of benzene sulphonyl urea derivatives
A new and improved herbicidal and plant growth regulating composition, and the method of manufacturing that composition. The new complex composition of the invention is an inclusion complex of one...
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4659735 |
Benzofuranyl (thienyl) propenyl derivatives useful as rodenticides
Heterocyclic compounds of the formula ##STR1## wherein X is --CHCH--, --O--or --S--; R 1 is a group Ar--R 2 or --CHCH--C(CH 3 )CH--R 21 ; Ar is phenyl, pyridyl, furyl or thienyl; R 2 ...
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4636343 |
Process for the preparation of insect repelling/killing film
A process for the preparation of insect repelling/killing film. The process involves forming a clathrate compound of fenitrothion with cyclodextrin or a starch decomposition product containing...
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4623641 |
Method of treating ulcers and erosions in the gastrointestinal system using PGI.sub.2 -methyl ester-beta cyclodextrin inclusion complexes
A new method is disclosed for the treatment and prevention of gastrointestinal ulcers or erosions which comprises the administration of a pharmaceutically effective amount of a PGI 2 methyl...
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4608366 |
Oral cyclodextrin and mobenzoxamine preparation
Disclosed herein is an oral mobenzoxamine preparation which comprises a clathrate compound of mobenzoxamine or a salt thereof and cyclodextrin. Since the clathrate compound remains extremely stable...
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4603123 |
Compounds having antiinflammatory activity, obtained by complexation of piroxican with β-cyclodextrin, and pharmaceutical compositions containing them
New inclusion compounds of 4-hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carbox
yamide-1,1-dio xide with α, β or γ cyclodextrins, obtained by reaction of said cyclodextrins and said...
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4599327 |
Dibenzo[bd]pyran derivatives, process for the preparation thereof and pharmaceutical compositions containing same
2,6-di-O-methyl-beta-cyclodextrin complexes of compounds of the formula (1a) ##STR1## wherein R 2 ' stands for C 1 to C 12 alkyl or a group of the formula ##STR2## in which R 11 is C 1 to C 4 ...
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4598070 |
Tripamide and cyclodextrin inclusion compound
An inclusion compound composed of tripamide and cyclodextrin markedly improves the solubility of tripamide which is effective for treatment of essential hypertension.
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4596795 |
Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
The administration of sex hormones, particularly testosteorne, progesterone and estradiol in the form of their complexes or inclusions with specific derivatives of cyclodextrins by the sublingual...
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4568667 |
Aqueous preparation containing vitamin E and saponins
An aqueous preparation containing vitamin E prepared by emulsifying or solubilizing vitamin E in an aqueous phase in the presence of a saponin shows excellent transparency and thermal stability,...
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4565807 |
Medicinal composition containing pirprofen and cyclodextrin and a method of use
The invention relates to a new medicinal composition containing α-[3-chloro-4-(3-pyrrolin-1-yl)-phenyl]-propionic acid as the pharmacologically active ingredient, having analgesic and...
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4524068 |
Cyclodextrin inclusion complex of piperonyl butoxide
The invention relates to new inclusion complexes of piperonyl butoxide formed with cyclodextrin. The new complex of the invention can be prepared by reacting cyclodextrin or a solution thereof...
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4518588 |
Process for the preparation of an inclusion complex of N-(1--phenylethyl)-3,3-diphenylpropylamine and the hydrochloride thereof respectively with cyclodextrin
An inclusion complex is disclosed of N-(1-phenylethyl)-3, 3-diphenyl-propylamine or its hydrochloride complexed with a cyclodextrin as well as a process for the preparation thereof and...
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4499085 |
Method of anoxia treatment using prostaglandin analogues
The invention provides a new method for the treatment of anoxia of brain cells using a PGI 1 derivative of the formula: ##STR1## wherein R 1 represents hydrogen or lower alkyl and R 2 represents...
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4499076 |
Elemental diets for liver diseases
An elemental diet of amino acids, carbohydrates, fats, vitamins and minerals.
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4479966 |
6,9-Methano-PGI2 analogues
Prostaglandin I 2 analogues of the formula: ##STR1## [wherein the symbol between the carbon atoms in positions 5 and 6 represents a single or double bond, Y represents ethylene or...
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4479944 |
Composition containing PGI.sub.2 analogs stabilized
Compositions which contain a PGI 2 analogue in solution in a solvent consisting of at least one pharmacologically-acceptable alcohol, polar aprotic solvent or middle chain triglyceride, or which...
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4478995 |
Complex compounds
A complex of an acid addition salt of (2'-benzyloxycarbonyl)phenyl trans-4-guanidinomethylcyclohexanecarboxylate and a cyclodextrin. The complex is useful for the treatment of ulcers.
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4470975 |
Method and composition for the elimination of water from an animal body
It has been found that certain insoluble hydrophilic cross-linked polysaccharides are useful pharmaceutical agents in diverting water elimination from the renal route to the gastrointestinal route,...
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4451457 |
Cyclodextrin and method for promoting the proliferation of intestinal bifidobacteria
Disclosed is an agent comprising cyclodextrin as the active ingredient and a method for using such agent to promote the proliferation of intestinal bifidobacteria in animals.
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4438106 |
Inclusion compound of eicosapentaenoic acid or docosahexaenoic acid with cyclodextrin
This disclosure describes an inclusion compound of cyclodextrin in which at least one guest compound selected from the group of eicosapentaenoic acid, docosahexaenoic acid and alkali metal salts...
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4425336 |
3,4-Dih ydroxy-N-[3-(4-dihydroxyphenyl)-1-methyl-n-propyl]-beta-phenethylamine cyclodextrin complexes
Cardiac contractility agents are provided which are 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methyl-n-propyl]-beta
-phenethylamin e cyclodextrin complexes.
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4424209 |
3,4-Di -isobutyryloxy-N- 3-(4-isobutyryloxyphenyl)-1-methyl-n-propyl!-beta-phene thylamine cyclodextrin complexes
Cardiac contractility agents are provided which are 3,4-di-isobutyryloxy-N- 3-(4-isobutyryloxyphenyl)-1-methyl-n-propyl!-beta- phenethylamine, preferably orally deliverable forms which are...
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4407795 |
Inclusion compound of p-hexadecylamino benzoic acid in cyclodextrin and method of use
An inclusion compound of p-hexadecylamino benzoic acid sodium salt in β-cyclodextrin which provides enhanced bioavailability of this antiatherosclerotic agent.
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4402946 |
Antithrombotic treatment
Certain salts of carbonyl sulfur dioxide adducts are found to demonstrate anticoagulant and/or venous antithrombotic activity.
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4383992 |
Water-soluble steroid compounds
Beta-cyclodextrin forms a water-soluble complex or inclusion compound with steroid compounds having a molecular structure smaller than the interior cavity in the doughnut-shaped molecular structure...
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4352793 |
Pharmaceutical composition comprising bencyclane fumarate and cyclodextrin
A composition comprising as the pharmaceutically active ingredient bencyclane fumarate and cyclodextrin. As compared with prior bencyclane fumarate preparations, this composition can greatly...
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4352794 |
Beta-cyclodextrin as anti-acne agent
A method for treating acne in which beta-cyclodextrin is applied to the acne typically in the form of a lotion, ointment, cream, gel or the like, in a concentration from 0.1-10, preferably 1-5%, by...
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4351846 |
3-Hydroxy and 3-oxo-prostaglandin analogues
Prostaglandin analogues of the formula: ##STR1## [wherein R 1 represents hydrogen or alkyl of 1 to 12 carbon atoms, R 2 represents a single bond or alkylene of from 1 to 5 carbon atoms, R 3 ...
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4305935 |
Bone formation stimulant
This is a bone formation stimulant containing vitamin D 3 or its derivative and acetylsalicylic acid or its formaceutically permissible salt. The present bone formation stimulant is used to cure...
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