|
Match
|
Document |
Document Title |
|
|
5646131 |
Method for solubilizing drugs using cyclodextrins and carboxylic acids
A method for enhancing the solubilization and/or complexation of a drug which is insoluble or sparingly soluble in water with cyclodextrin, comprising combining the drug with cyclodextrin together...
|
|
|
5637575 |
Methods of inhibiting restenosis
Disclosed are compositions and methods effective for inhibiting restenosis. In particular, the present invention provides compositions for inhibiting undesired smooth muscle cell growth or...
|
|
|
5631244 |
mono(6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue, process for their preparation and their uses
Mono (6-amino-6-deoxy)cyclodextrin derivatives substituted in the 6-position by an α-amino acid residue. These derivatives correspond to the following general formula: ##STR1## in which: CD...
|
|
|
5629299 |
Hydrolytic stabilizer for unstable organic ions
Storage-stable aqueous solutions of hydrolytically unstable organic ionic compounds and cyclodextrins, which cyclodextrins are capable of forming hydrolytically stable inclusion complexes with the...
|
|
|
5624914 |
Lipophilic oligosaccharide antibiotic salt compositions
Pharmaceutically acceptable compositions of matter comprising a lipophilic oligosaccharide antibiotic, e.g., the everninomicin-type antibiotic of Formula III, at least a stoichiometric amount of a...
|
|
|
5624907 |
Beverage for preoperative intake
A beverage for preoperative use is disclosed which comprises a hypotonic aqueous solution of a carbohydrate mixture consisting of at least one member from each of the groups, mono-, di-, and...
|
|
|
5620964 |
Compositions for treating and inhibiting gastric and duodenal ulcers
A composition for treating and/or inhibiting gastric and duodenal ulcers, comprising an oligosaccharide selected from the group consisting of Formula I ##STR1## or a mixture thereof; wherein: X...
|
|
|
5620961 |
Fructose ester-β-cyclodextrin complexes and processes for making and using same
A specialized derivative of fructose in which the compound is a fructose ester complexed with β-cyclodextrin. Preferably, the fructose derivative is fructosehexanoate β-cyclodextrin complex, and...
|
|
|
5614167 |
Test patch and its use for demonstrating contact allergy
|
|
|
5612321 |
Antioxidant grafted polysaccharides
Grafted polysaccharide compositions comprising polysaccharides grafted with antioxidants on at least one hydroxyl group of the polysaccharide. The use of antioxidant grafted polysaccharides or...
|
|
|
5605892 |
Compositions of arginine amide with cyclodextrin of caffeine, and methods of use
An aqueous agent comprising at least one arginine amide selected from the group consisting of (2R,4R)-4-methyl-1-[N 2 -((RS)-3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-ar
ginyl]-2-piper...
|
|
|
5593978 |
Growth promoting composition for fish and method of using the same
A method for promoting growth in fish comprising administering a low level dosage amount of zearalanol to fish. The zearalanol may be conveniently administered to the fish via a novel fish feed...
|
|
|
5591725 |
Water-in-oil dispersion
The present invention is concerned with a plastic dispersion containing from 5-65 wt. % of a continuous fat phase and from 95-35 wt. % of a gelling polysaccharide containing dispersed aqueous...
|
|
|
5587399 |
Method for preparing medical foods for the nutritional support of infants/toddlers with metabolic diseases
The present invention involves a method of preparing a nutritional product in which a powder base containing fats, carbohydrates, vitamins, minerals and trace elements is mixed with specific amino...
|
|
|
5578585 |
Pleuromutilin derivative complexes
Complexes and pharmaceutical preparations containing complexes of the pleuromutilin derivative of formula I ##STR1## in free base or in acid addition or quaternary salt form and cyclodextrin are...
|
|
|
5573773 |
Stable highly concentrated formulations of fluorescein derivatives
The present invention relates to stable highly concentrated formulations of specific fluorescein derivatives, to the preparation of said formulations and the use thereof, especially for the...
|
|
|
5574019 |
Method of perfusing a primate
The present invention relates to the field of compositions of matter, disclosing compositions of matter which as aqueous solutions, may be used to perfuse a living or non-living subject in need of...
|
|
|
5562921 |
Stable solid pharmaceutical compositions containing enalapril maleate
Enalapril maleate is unstable when associated with many excipients commonly used in the manufacture of pharmaceutical compositions. Stable solid compositions are provided by mixing enalapril...
|
|
|
5561116 |
Solid product containing propolis components, and preparation and uses thereof
A solid, water-dispersible composition containing propolis components. This composition is prepared by extracting intact or dewaxed propolis with an aqueous solution of a water-soluble organic...
|
|
|
5541202 |
New leukotriene-B4 Antagonists and their use as pharmaceutical agents
1. Leukotriene-B 4 antagonists of formula I, ##STR1## are described, in which X represents C 1 -C 4 -alkoxy or --S(O) p --(C 1 -C 4 )-alkyl, p represents 0, 1 or 2 Y represents a hydrogen atom...
|
|
|
5529915 |
Lyophilized polyethylene oxide modified protein and polypeptide complexes with cyclodextrin
Disclosed are lyophilized biologically active proteinaceous compositions containing low diol polyalkylene oxide, such as polyethylene glycol, covalently attached to a biologically active...
|
|
|
5527783 |
Dry and Porous galenic form based on plants, its method of preparation and its applications
Solid compositions based on plants, capable of being converted to a dry and porous galenic form (lyophilized or equivalent form) which is undivided or powdered. Said dry and porous galenic form...
|
|
|
5525596 |
Absorption enhancer/solubilizer combination for improved bioavailability of a zwitterionic compound
Intestional absorption of zwitterionic compounds is enhanced when the compound is delivered with the absorption enhancer palmitoyl carnitine chloride and the solubilizing agent β-cyclodextrin when...
|
|
|
5519011 |
Food composite performing function of improving serum lipid
A method for decreasing a content of lipid and total cholesterol in serum and increasing a relative content of HDL cholesterol in serum which comprises the steps: (a) providing a pyrodextrin...
|
|
|
5519012 |
Inclusion complexes of optically active 1,4-dihydropyridines with methyl-β-cyclodextrin
Novel inclusion complexes of racemic 1,4-dihydropyridines and enantiomers thereof of the formula ##STR1## wherein R represents a phenyl group, substituted with nitro, trifluoromethyl,...
|
|
|
5516766 |
Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
Polyionic derivatives of cyclodextrin polymers and cyclodextrins immobilized on a solid surface are disclosed. Compositions and methods for separating a molecular species, including but not limited...
|
|
|
5514665 |
Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans
Methods for reducing the risk of or preventing infections by bacterial pathogens in vivo. In particular, a method for reducing the risk of P. aeruginosa infection in vivo in compromised hosts such...
|
|
|
5514668 |
Composition for removing or inactivating harmful components in blood or other extracellular body fluids
A composition for removing or inactivating harmful components including virus from blood or other extracellular liquids comprises a crown ether compound substituted on a polysaccharide, preferably...
|
|
|
5512290 |
Compositions containing 2-acetyl-1-pyrroline
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
|
|
|
5506216 |
Cyclodextrin-biocide complex
The invention concerns a complex of cyclodextrin and an organic biocide, wherein the organic biocide has a maximum water-solubility of 0.15% (w/v) at a temperature of 25° C., a process for the...
|
|
|
5498408 |
Oral rehydration composition
The invention relates to an oral rehydration formula containing a conventional carbohydrate, rice flour and carrot powder as carbohydrate sources.
|
|
|
5494901 |
Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
A topical composition comprising an amount of a carbonic anhydrase inhibitor and an amount of β-cyclodextrin derivative effective in increasing the bioavailability of the carbonic anhydrase...
|
|
|
5490978 |
Block copolymers of polysaccharides and polyalkylene oxides
Polysaccharides (e.g., dextran) of different molecular weights were substituted at the anomeric carbon with polyalkylene oxides of different molecular weights to give novel diblock copolymers. The...
|
|
|
5486508 |
Cyclodextrin composition
A pharmaceutical composition comprising a slightly water-soluble drug, a cyclodextrin and a water-soluble organic solvent is disclosed. The composition improves water-solubility and stability of...
|
|
|
5484777 |
Pancreatic cholesterol esterase inhibitor
This invention encompasses a method and compositions which inhibit pancreatic cholesterol esterase and triglyceride lipase and hence, lower cholesterol and triglycerides in the blood stream.
|
|
|
5484776 |
Process for the production of stable liquid form of beta-blocker-containing medicaments with controlled release of the active constituent for oral administration
This invention relates to a process for the production of optimally stable orally administrable solution forms of medicaments containing high-molecular polysaccharides, with controlled release of...
|
|
|
5476852 |
Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
A method of topically treating subjects suffering from acne, hyperkeratotic dermatoses and photo-aging of the skin, by administering to the skin of said subjects an effective amount of the...
|
|
|
5472954 |
Cyclodextrin complexation
The invention provides a method for enhancing the complexation of a cyclodextrin with a lipophilic and/or water-labile active ingredient which is a drug, cosmetic additive, food additive or...
|
|
|
5464827 |
Esterified polyanionic cyclodextrins as smooth muscle cell proliferation inhibitors
This invention relates esterified polysulfated cyclodextrins, their use in treating diseases and conditions which are characterized by excessive smooth muscle cell (SMC) proliferation such as...
|
|
|
5455236 |
5,10-methylenetetrahydrofolic acid-cyclodextrin inclusion compounds
The invention relates to novel cyclodextrin inclusion compounds of 5,10-methylenetetrahydrofolic acid. The surprisingly good stability of these compounds makes possible their pharmaceutical use for...
|
|
|
5447920 |
Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin
A cosmetic composition comprising an inclusion product having a slightly water-soluble component with a hydroxyalkylated cyclodextrin formulated therein.
|
|
|
5441944 |
Substituted cyclodextrin sulfates and their uses as growth modulating agents
The invention relates to highly water soluble substituted α-, β- or γ-cyclodextrin sulfates associated with a physiologically acceptable cation. Pathological or otherwise undesirable cell or...
|
|
|
5439894 |
Dextrin derivatives for the treatment of acidic conditions
Disclosed is a pharmaceutical composition comprising a dextrin derivative in which a proportion of the hydroxyl groups of dextrin are replaced by basic groups. Such compositions are useful for the...
|
|
|
5431925 |
Nutritive composition for prevention and therapy of infection diseases caused by immunosuppression
Disclosed is a nutritive composition for patients being treated with anticancer drugs, which comprises 1-5 mg weight % of a retinoid compound in the solid content of the composition composed of...
|
|
|
5422347 |
β-cyclodextrin complexes of miconazole and econazole
The econazole and miconazole complexes with β-cyclodextrin show in vitro a good anti-fungal activity with a wide spectrum and, if locally applied, are well tolerated and more effective than the...
|
|
|
5418225 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
A topical composition comprising an amount of a carbonic anhydrase inhibitor and an amount of β-cyclodextrin derivative effective in increasing the bioavailability of the carbonic anhydrase...
|
|
|
5416078 |
Fluid resuscitation
The invention relates to fluid resuscitation of the human or animal body by administration of deferoxamine (DFO) and a water-soluble biopolymer. The DFO and the biopolymer are preferably bonded...
|
|
|
5403828 |
Purification of cyclodextrin complexes
A method is provided for purifying crude inclusion complexes of cyclodextrin which is used as a host material, in combination with a guest material, such as light mineral oil. After the crude...
|
|
|
5391545 |
Combating of undesired organisms
Undesired organisms, including insects, mites and fungi, may be combated by application of a liquid composition which comprises starch dextrin or an analogous derivative of amylopectin as an active...
|
|
|
5385891 |
Polysulfate of β-cyclodextrin derivative and process for preparing the same
Disclosed is a polysulfate of a β-cyclodextrin in which at least one of 7 D-glucose units constituting the β-cyclodextrin is a unit represented by the formula (I-a): ##STR1## wherein R 1 is an...
|