|
Match
|
Document |
Document Title |
|
|
7572798 |
Combi-molecules having signal transduction inhibitory properties and DNA damaging properties
The present invention relates to a series of new chemical agents that demonstrate anti-tumor activity. More particularly, the present invention relates to molecules, referred to as...
|
|
|
7482377 |
Pharmaceutical compositions and methods of treatment based on diclofenac
New pharmaceutical compositions for oral use containing diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to diclofenac are described. These...
|
|
|
7468446 |
Substituted heterocyclic compounds and uses thereof
The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or...
|
|
|
7358262 |
Identification of genotype-selective anti-tumor agents
The present invention relate to methods of identifying a genotype-selective agent. In certain embodiments, the invention relates to agents that are selectively toxic to engineered human tumorigenic...
|
|
|
7319096 |
Thyroid hormone receptor antagonists for cardiac and metabolic disorders II
This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders,...
|
|
|
7291599 |
Use of inhibitors of enzymes having activities of amino peptidase N and/or dipeptidyl peptidase IV and of pharmaceutical preparations thereof for a therapy and prevention of chronical neurodegenerative diseases
The invention relates to a process for the treatment of neurodegenerative diseases wherein mis-folded proteins accumulate in characteristic lesions and contribute substantially to a pathogenesis...
|
|
|
7285572 |
CaSR antagonist
The present invention provides a compound having a calcium-sensitive receptor antagonistic action, a pharmaceutical composition containing the compound, particularly a calcium receptor antagonist...
|
|
|
7229969 |
Combinations of enzyme inhibitors and the use thereof
Combination of inhibitors of dipeptidyl peptidase IV (DP IV) and enzymes having the same substrate specificity (DP IV-analogous enzymatic activity) and inhibitors of alanyl aminopeptidase...
|
|
|
7141238 |
Compositions for reducing UV-induced inhibition of collagen biosynthesis in human skin
Exposure of human skin to ultraviolet (UV) radiation from the sun not only induces the production of enzymes (matrix metalloproteinases) that degrade collagen, but also inhibits the synthesis of...
|
|
|
7122580 |
Aryl and heteroaryl compounds and methods to modulate coagulation
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of...
|
|
|
7109164 |
Aniline-derived ligands for the thyroid receptor
New thyroid receptor ligands are provided which have the general formula
in which:
X is —O—, —S—, —CH 2 —, —CO—, or —NH—; Y is —(CH 2 ) n — where n is an integer...
|
|
|
7037914 |
Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient
A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I)
(wherein all symbols are as defined in the specification), a non-toxic acid...
|
|
|
7014864 |
Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more...
|
|
|
6984389 |
Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a...
|
|
|
6982097 |
Biocidal compositions and methods of using same
This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using...
|
|
|
6974595 |
Pharmaceutical compositions based on Diclofenae
New pharmaceutical compositions for oral use containing Diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to Diclofenac are described. These...
|
|
|
6962774 |
Method for dry-preserving multicellular organism tissue at ordinary temperatures
A tissue of a multicellular organism is gradually dried during cultivation. After the tissue has been completely dehydrated, water is added to the tissue for its recovery. The tissue of the...
|
|
|
6962714 |
Critical fluid antimicrobial compositions and their use and generation
The present invention relates to antimicrobial compositions including a critical, near critical, or supercritical (densified) fluid and an antimicrobial agent, to methods of forming these...
|
|
|
6953786 |
Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof
Disclosed are methods for treating, preventing, or inhibiting cancer in a subject comprising administering at least one polyphenolic compound and at least one inhibitor of reactive oxygen species...
|
|
|
6943194 |
Synthesis of phenstatin and prodrugs thereof
A newly discovered antineoplastic compound denominated “phenstatin” is herein described as are synthetic methods for producing phenstatin and the active prodrug thereof. Phenstatin was...
|
|
|
6919072 |
Methods and compositions for reducing collagen loss due to chronological aging in human skin
Chronological aging of human skin can be delayed with the topical application of an MMP inhibitor, preferably a retinoid (an indirect MMP inhbitor); retinoids also normalize procollagen...
|
|
|
6911473 |
Detectable agent for wood treatment and method for its detection
The present invention relates to a composition comprising an organic preservative acid and a UV-active indicator substance for preserving wood and for detection of the sufficient preservation of wood.
|
|
|
6835749 |
Sulfohydroxamic acids and sulfohydroxamates and their use as MEK inhibitors
Sulfohydroxamic acid diarylamines and derivatives thereof; compositions made from them; and methods of using them.
|
|
|
6803057 |
Hydrogen peroxide disinfectant with increased activity
An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations...
|
|
|
6800605 |
Aniline-derived ligands for the thyroid receptor
New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH 2 —, —CO—, or —NH—; Y is —(CH 2 ) n — where n is an integer from 1...
|
|
|
6797728 |
Use of intracellular calcium chelators to increase surfactant secretion in the lungs
Pulmonary surfactant is required in order to reduce surface tension in the lungs so that less effort is needed to reinflate the lungs after exhalation. A number of diseases and conditions exist...
|
|
|
6787573 |
Antiviral therapy
The invention relates to the field of antiviral agents, and more specifically to antiviral therapy. The invention provides use of at least one compound or mixture of compounds of the general...
|
|
|
6787528 |
Inhibitors of intestinal apical membrane Na/phosphate co-transportation
The compounds of formula (I) are hydrophilic aryl phosphate, thiophosphate, and aminophosphate intestinal apical membrane Na-mediated phosphate co-transportation inhibitors. The compounds can be...
|
|
|
6749869 |
Acidic aqueous chlorite teat dip providing shelf life, sanitizing capacity and tissue protection
The mastitis control teat dip composition of the invention provides rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition...
|
|
|
6723750 |
Photodynamic therapy for pre-melanomas
Method for treating dermal pre-melanoma conditions which include administering an effective amount of a photosensitive agent to a dermal pre-melanoma cell and activating the photosensitive agent,...
|
|
|
6706290 |
Methods for eradication of nanobacteria
Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The...
|
|
|
6699510 |
Acidic aqueous chlorite teat dip with improved visual indicator stability, extended shelf life, sanitizing capacity and tissue protection
The mastitis control teat dip composition having a visible indicator aspect of the invention provides a softening, soothing, smoothing, relaxing property, a rapid initial kill, a useful highly...
|
|
|
6683069 |
Methods and compositions for reducing UV-induced inhibition of collagen synthesis in human skin
Exposure of human skin to ultraviolet (UV) radiation from the sun not only induces the production of enzymes (matrix metalloproteinases) that degrade collagen, but also inhibits the synthesis of...
|
|
|
6656967 |
Fungicidal phenylimidate derivatives
The invention provides fungicidal compounds of formula I and salts thereof: wherein the various radicals and substituents are as defined in the description, fungicidal compositions containing...
|
|
|
6653321 |
Naphthylsulfonic acids and related compounds as glucose uptake agonists
Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or...
|
|
|
6642260 |
Nitric oxide donors and pharmaceutical compositions containing them
The present invention provides a compound containing at least one sulfhydryl group and at least one NO donor group, wherein said compound contains one or more protected sulfhydryl groups linked to...
|
|
|
6635678 |
Pharmaceutical composition for treating fecal incontinence
Fecal incontinence and anal itch can be treated by administration, more particularly by local application to the anus, of an a adrenergic blocker, nitric oxide synthase inhibitor, prostaglandin F...
|
|
|
6630516 |
Methods and compositions for preventing and treating chronological aging in human skin
The deleterious effects of the passage of time on human skin (i.e., chronological aging of human skin) can be prevented and treated with the topical application of a retinoid, preferably retinol....
|
|
|
6599941 |
Insecticide and insect repellant compositions
A non-toxic, environmentally safe and easily employable insecticide and insect repellent is achieved by providing an aqueous composition incorporating ethanolamine based compounds, either...
|
|
|
6552085 |
Compositions containing hypoglycemically active stilbenoids
The use of isolated or purified stilbenoid compounds including longistyline A-2-carboxylic acid as hypoglycemic agents or to lower serum glucose levels is described. The invention also relates to...
|
|
|
6545050 |
Aryl sulphonamide amino acid esters and analogues
The present invention relates to novel amino acid esters of arylsulphonamides and analogues, to processes for their preparation and to their use for the prophylaxis and treatment of...
|
|
|
6541522 |
Methods of using compositions containing hypotriglyceridemically active stilbenoids
The use of isolated or purified stilbenoid compounds including longistyline A-2-carboxylic acid as a dietary supplement to mammals suffering from elevated triglyceride levels is described. The...
|
|
|
6537991 |
Method of treating a peripheral neuropathic pain
The invention provides methods for treating and preventing neuropathic pain which comprise the administration of an effective amount of an antagonist of the pain-enhancing effects of E-type...
|
|
|
6492424 |
Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders
Novel glucocorticoid and thyroid receptor ligands as provided which have the general formula (I): in which R 1 is an aliphatic hydrocarbon, an aromatic hydrocarbon, carboxylic acid or ester...
|
|
|
6478946 |
METHOD OF PRODUCING FULVIC, HUMIC, AND ULMIC ACID FOR USE AS AN ELECTROLYTE IN PRODUCING IONIZED BACTEREACIDES FROM PRECIOUS METALS AND METHOD OF PRODUCING IONIZED BACTEREACIDES FROM PRECIOUS METALS AND ORGANIC ACIDS
A method of preparing organic acids (fulvic, humic, and ulmic) for use as an electrolyte for producing high ionizations of precious metals (such as silver) which entails leaching out the organic...
|
|
|
6455582 |
Sulohydroxamic acids and sulohyroxamates and their use as MEK inhibitors
Sulfohydroxamic acid diarylamines of formula (I), in which the variables are as defined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer,...
|
|
|
6428772 |
Acne treatment composition with cooling effect
A composition for topical aerosol application contains, by weight, a) about 20 to 90% of an active mixture in the form of a solution, gel or lotion with salicylic acid or benzoyl peroxide as active...
|
|
|
6420394 |
Topically applied pharmaceutical formulation
The present invention relates to a novel pharmaceutical formulation for the topical application of drugs, particularly non-steroidal anti-inflammatory drugs (NSAID's), comprising a therapeutically...
|
|
|
6410602 |
Method of increasing the production and improving the quality of semen
A method of increasing the volume, the total sperm count and the reproductive performance of semen from human and animal males, is described. The method comprises administration of an effective...
|
|
|
6410596 |
Compositions containing hypoglycemically active stillbenoids
The use of isolated or purified stilbenoid compounds including longistyline A-2-carboxylic acid as hypoglycemic agents or to lower serum glucose levels is described. The invention also relates to...
|