Matches 101 - 150 out of 547 < 1 2 3 4 5 6 7 8 9 10 11 >
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6329425 Modulation of inflammation related to Columnar epithelia  
This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar...
6323241 Prostaglandin compositions and methods of treatment for male erectile dysfunction  
The invention provides methods of treating erectile dysfunction comprising the step of placing within the fossa navicularis of the patient an effective erection-inducing amount of a prostaglandin E...
6306841 Treatment of female sexual dysfunction  
Methods and formulations for treating female sexual dysfunction are provided. A pharmaceutical composition formulated so as to contain a selected vasoactive agent is administered to the vagina,...
6303588 Therapeutic methods utilizing naturally derived bio-active complexes and delivery systems therefor  
Methods are disclosed for correcting biological information transfer in a patient in need of such therapy which comprise administration to a patient of a composition comprising a therapeutically...
6294563 Combinations of prostaglandins and brimonidine or derivatives thereof  
The invention concerns combinations of alpha adrenergic agents such as brimonidine and its derivatives as represented by formula (I) below ##STR1## wherein each Y is independently selected from the...
6291528 Prostaglandin E1/F2 in combination with prostaglandin F2α for enhancing female sexual arousal  
A method of treating and a composition for treating female sexual arousal dysfunction, comprising administering to the patient a unit dose of a formulation comprising an effective amount of a...
6291522 Cyclopentane heptan(ENE)oic acid, 2-thiocarbamoyloxy and 2-carbamoyloxy compounds as therapeutic agents  
The invention relates to the use of cyclopentane heptan(ene)oic acid, 2-thiocarbamoyloxy and carbamoyloxy as therapeutic agents e.g. as ocular hypotensives. The compounds used in accordance with...
6291521 Anti-portal hypertensive agent  
The present invention provides an anti-portal hypertensive agent comprising a 15-keto-prostaglandin compound as an active ingredient.
6291516 Regulators of the hedgehog pathway, compositions and uses related thereto  
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function...
6288119 11,15-O-dialkylprostaglandin E derivatives, process for producing the same, and drugs containing the same as the active ingredient  
The present invention provides 11,15-O-dialkyl prostaglandin E derivatives of formula (I) ##STR1## (wherein all symbols are as described in Specification), or non-toxic salts thereof or...
6284773 Therapeutic combinations comprising a selective estrogen receptor modulator and prostaglandin E2  
This invention is directed to pharmaceutical combination compositions and methods comprising (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6 ,7,8-tetrahydr onaphthalene-2-ol or a...
6280778 Process for preparing natural product derivatives from plants in a single step  
A process is disclosed, for preparing a derivative of a targeted natural product from plants. The targeted natural product is extracted from the desired part of the plant and the targeted natural...
6265440 Prostaglandins E and anti ulcers containing same  
The novel 13,14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro-15-keto-prostaglandins E of the invention have...
6258844 Cyclopentane (ene) oic acid, 2-alkenyl derivatives as therapeutic agents  
The invention relates to the use of omega chain modified prostaglandins as ocular hypotensive. The derivatives used in accordance with the invention are encompassed by the following structure...
6255277 Localized use of nitric oxide-adducts to prevent internal tissue damage  
A method for preventing adverse effects associated with the use of a medical device in a patient by introducing into the patient a device of which at least a portion includes a prophylactic or...
6242485 Endothelin antagonist  
An endothelin antagonist comprising as the active ingredient a prostanoic acid derivative wherein the α-chain has eight or more skeletal carbon atoms.
6239157 Inhibition of osteoclastogenesis  
A method for inhibiting the differentiation of CD34+ cells into osteoclasts by treating the cells with a peroxisome proliferator-activated receptor-γ agonist.
6235781 Prostaglandin product  
A pharmaceutical product comprising an aqueous prostaglandin formulation and a polypropylene container are disclosed. Aqueous prostaglandin formulations are more stable in polypropylene containers...
6235780 ω-cycloalkyl-prostaglandin E1 derivatives  
6235779 Use of cis-Δ4 analogs of prostaglandins as ocular hypotensives  
Cis-Δ 4 analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
6232344 13-Oxa prostaglandins for the treatment of glaucoma and ocular hypertension  
13-Oxa analogs of certain prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
6232343 Ophthalmic preparations  
An ophthalmic preparation which exhibits excellent pharmacological effects for various ophthalmic diseases is disclosed. The ophthalmic preparation according to the present invention contains a...
6225348 Method of treating macular degeneration with a prostaglandin derivative  
A method of treating age-related macular degeneration in an eye is described, comprising contacting the eye with a therapeutic amount of a prostaglandin F 2 α derivative. The preferred...
6225347 9-halogen-(Z)-prostaglandin derivatives, process for their production and their use as pharmaceutical agents  
The invention relates to 9-halogen-(Z) prostane derivatives of formula I ##STR1## in which ##STR2## Z represents the radicals Hal represents a chlorine or fluorine atom in the alpha or beta...
6210343 Use of misoprostol or/and misoprostol acid for diagnosis of vascular damage in a subject with erectile dysfunction  
A method is provided for diagnosing vascular damage in a subject with erectile dysfunction that includes applying an effective dose of a therapeutic formulation having an excipient and at least one...
6197821 Endothelin antagonist  
The present invention provides an antagonist for endothelin which is considered to have a relation to hypertension, Buerger is disease, asthma, eyegrounds diseases, and the like. Said endothelin...
6197801 Injectable pharmaceutical composition for treatment and reversal of erectile dysfunction  
An injectable pharmaceutical composition for treatment of erectile dysfunction. The composition includes prostaglandin E-1, and optionally further includes levsin and/or additional vasodilators...
6187818 Prostaglandins formulation and process  
This invention comprises new formulations and methods of preparing a new formulations of prostaglandins and in particular dinoprost tromethamine, where the pH of the formulation is adjusted to...
6187756 Composition and methods for treatment of neurological disorders and neurodegenerative diseases  
It has been discovered that the stimulation of β-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo...
6184250 Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension  
Disclosed is the use of cloprostenol and fluprostenol analogues and combinations thereof with other medicaments for the treatment of glaucoma and ocular hypertension and ophthalmic compositions...
6166073 Combinations of DP and FP type prostaglandins for lowering IOP  
Compositions containing DP-agonist and FP-agonists prostaglandin agonists and methods of their use in treating glaucoma or ocular hypertension are disclosed.
6160013 14-aza prostaglandins for the treatment of glaucoma and ocular hypertension  
14-Aza analogs of PGF 2 α, PGD 2 , and PGE 2 and methods of their use in treating glaucoma and ocular hypertension are disclosed.
6156799 Method of increasing bone volume using non-naturally-occurring FP selective agonists  
The present invention relates to novel methods of increasing bone volume comprising the administration of a non-naturally-occurring selective FP agonist to a subject in need of such treatment. This...
6156785 Method for increasing oxygen tension in the optic nerve and retina  
There is disclosed a method for increasing retinal and optic nerve head oxygen tension by application of a composition comprising carbonic anhydrase inhibitors to the eye.
6150411 Use of DHA as a pharmaceutical composition  
6133230 Method and pharmaceutical composition for chondrostimulation with a prostaglandin (e.g. misoprostol) and TGF-β, optionally in combination with IGF-1  
A pharmaceutical composition comprising a prostaglandin such as misoprostol and TGF-B in amounts sufficient to stimulate production of chondrocyte matrix is disclosed which exhibit therapeutic...
6127413 Ocular depressor  
This invention relates to an agent for decreasing ocular tension comprising as an effective ingredient a 4,8-inter-m-phenylene PGI 2 derivative represented by the formula: ##STR1## or a...
6124353 Method of treating ocular hypertension with 8-epi prostaglandins  
The present invention provides a method of treating ocular hypertension which comprises applying to the eye an amount sufficient to treat ocular hypertension of a compound of formula (I) ##STR1##...
6110969 Cycloalkyl-prostaglandin E.sub.2 derivatives  
A ω-cycloalkyl-prostaglandin E 2 derivatives of the formula (I) ##STR1## wherein R is carboxy or hydroxymethyl; R 1 is oxo, methylene or halogen atom; R 2 is H, OH or C1-4 alkoxy; R 3 is H,...
6103765 Methods for treating male erectile dysfunction  
Administration of a pharmaceutical composition comprising: (a) a vasodilator; and (b) a 15-hydroxyprostaglandindehydrogenase inhibitor is effective for the treatment of male erectile...
6083501 Drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation in the lung and model animals of the diseases  
A drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation, as well as a model animal of fibrinoid formation or thrombus formation in the lung is disclosed....
6048895 Aromatic C16-C20 substituted tetrahydro prostaglandins useful as FP agonists  
The invention provides novel PGF analogs. In particular, the present invention relates to compounds having a structure according to the following formula: ##STR1## wherein R 1 , R 2 , R 3 , R 4 ,...
6046244 Topical compositions for prostaglandin E.sub.1 delivery  
A topical composition of a semi-solid consistency suitable is provided for transdermal application of prostaglandin E 1 . The composition comprises prostaglandin E 1 , a penetration enhancer, a...
6046240 Methods for treating female sexual dysfunction  
A method for treating female sexual dysfunction or for female sexual enhancement comprises administering to the vagina a composition comprising a prostanoid compound having a vasodilating effect in...
6043275 3,7-dithiaprostanoic acid derivative  
A 3,7-dithiaprostanoic acid derivative of the formula (I) ##STR1## (wherein, R 1 is OH, C1.about.6 alkyloxy, NR 6 R 7 (R 6 , R 7 are H, C1.about.6 alkyl.); R 2 is H, OH; R 3 is single bond,...
6043224 Compositions and methods for treatment of neurological disorders and neurodegenerative diseases  
It has been discovered that the stimulation of β-adrenergic receptors, which activate cAMP formation, give rise to increased APP and GFAP synthesis in astrocytes. Hence, the in vitro or in vivo...
6037368 8-iso- prostaglandins for glaucoma therapy  
The present invention relates to the use of 8-iso prostaglandins and their derivatives for decreasing intraocular pressure, for example in the treatment of glaucoma It is based, at least in part,...
6034133 Use of a virucidal hand lotion to prevent the spread of rhinovirus colds  
Frequent application of a virucidal hand lotion containing malic acid, citric acid, and a C 1 -6 alcohol will prevent the hand-to-hand transmission of rhinoviruses and reduce the incidence of the...
6031002 Method for enhancing female sexual response and a composition therefor  
A method for enhancing female sexual response in which topically administered to the clitoris of the female subject and the surrounding tissue is a pharmaceutically-acceptable composition whose...
6031001 Use of prostaglandins  
Methods for topical treatment of psoriasis are disclosed comprising applying to the skin a composition comprising an effective amount of a therapeutically active and physiologically acceptable...
Matches 101 - 150 out of 547 < 1 2 3 4 5 6 7 8 9 10 11 >