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5725894 |
Coccidiosis-relieving agent and feed containing the same
A coccidiosis-relieving agent comprising cashew nut shell oil and/or anacardic acids as an active ingredient and a feed for relieving coccidiosis comprising cashew nut shell oil and/or anacardic...
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5719184 |
3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds
The present invention relates to novel 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating...
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5712310 |
Suspension of substantially water-insoluble drugs and methods of their manufacture
A stable aqueous suspension including a substantially water-insoluble drug suspended in a completely water-soluble mixture including hydroxypropylmethylcellulose, polyoxyethylene sorbitan...
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5709855 |
Compositions of spirulina algae and omega fatty acids for treatment of inflammation and pain
A composition for preventing or treating inflammation and/or pain by topical administration are disclosed. The composition contains an omega fatty acid in combination with spirulina. Preferably,...
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5710178 |
Compositions and methods for therapy and prevention of pathologies including cancer, AIDS, and anemia
Compositions and methods of treating anemia, cancer, AIDS, or severe β-chain hemoglobinopathies by administering a therapeutically effective amount of phenylacetate or pharmaceutically acceptable...
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5710179 |
Antitumor agent
An antitumor agent comprising as an effective ingredient 3- 4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl!-2-propenoic acid obtained from propolis and/or its physiologically acceptable salt(s). The...
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5690967 |
Compositions for improved topical delivery of lactic acid
Compositions for improved topical delivery of lactic acid comprising lactic acid and an amphoteric or pseudoamphoteric agent.
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5674902 |
Method of inhibiting hyperplasia to a mammal in need thereof
The present invention relates to a method of inhibiting a protein kinase C-mediated biological response, such as, hyperplasia. The method comprises administering to a mammal a non-tumor promoting...
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5668182 |
Method of calming or sedating an animal with a hydroxy benzaldehyde compound
Various hydroxy benzaldehyde derivatives including Vanillin, a natural product derived from the vanilla bean that is commonly used as a flavoring agent, is administered by injection (i.v., i.m.,...
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5658950 |
Therapeutic agent for glaucoma and ocular hypotensive agent
The present invention provides a novel drug for treating glaucoma. The present invention relates to a therapeutic agent for glaucoma and an ocular hypotensive agent, which comprise an...
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5658947 |
Method and composition for selectively inhibiting melanoma using betalinic acid
A composition and method of inhibiting tumor growth and treating malignant melanoma without toxic side effects are disclosed. Betulinic acid or a betulinic acid derivative is the active compound of...
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5654337 |
Topical formulation for local delivery of a pharmaceutically active agent
This invention relates to a composition useful in the delivery of pharmaceutically active agents through the skin. In one embodiment of the invention, the composition is formulated with a...
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5654338 |
Preparation of optically active α-(hydroxyphenoxy)alkanecarboxylic acids and derivatives thereof
Optically active α-(hydroxyphenoxy)-alkanecarboxylic acids or derivatives thereof, for example D-2-(4-hydroxyphenoxy)propionic acid or lower alkyl ester thereof, are prepared by (a) saponifying an...
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5643960 |
Method of delaying onset of alzheimer's disease symptoms
The present invention relates, in general, to a method of preventing or delaying the onset of Alzheimer's disease and related neurodegenerative disorders. The method involves the administration to...
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5631296 |
Drugs containing S(+)-ibuprofen
Rapid-release S(+)-ibuprofen pellets are proposed whose bioavailability is comparable to that of commercially available racemate formulations. The rapid release of the active substance is promoted...
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5622990 |
Ibuprofen lysinate pharmaceutical formulation
Pharmaceutical ibuprofen lysinate dry granulation formulations comprising about 90% w/w ibuprofen lysinate are useful for the preparation of tablets containing ibuprofen lysinate.
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5618516 |
Method of reducing subcutaneous inflammation by the topical application of a hydrophilic pharmaceutical composition containing ketoprofen lysine salt
A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution...
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5618837 |
PDGF antagonists III
Methods for inhibiting intimal hyperplasia in the vasculature of mammals, including primates, are disclosed. The methods comprise administering to the mammal an effective amount of Brefeldin A or a...
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5614171 |
Hydrophilic pharmaceutical composition containing ketoprofen lysine salt for topical use
A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution...
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5612376 |
Method of treating wrinkles using 3-phenyllactic acid
A method for visibly reducing a facial wrinkle by topically applying to the wrinkle 3-phenyllactic acid or a topically effective salt thereof.
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5612382 |
Composition for percutaneous absorption of pharmaceutically active ingredients
A pharmaceutical composition for transdermally delivering pharmaceutically active ingredients through skin or mucosal tissues. The composition comprises pharmaceutically active ingredients in...
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5604259 |
Treatment of bone loss with ibuprofen or flurbiprofen
This invention relates to the use of flurbiprofen and ibuprofen, their pharmaceutically acceptable salts and esters in a method of increasing bone mass and the treatment and prevention of bone mass...
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5599843 |
Method of treating wrinkles using 2-phenyllactic acid
A method for visibly reducing a facial wrinkle by topically applying to the wrinkle 2-phenyllactic acid or a topically effective salt thereof.
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5571841 |
Method of treating wrinkles using mandelic acid
Composition and method for enhancing therapeutic effects of topically applied agents are disclosed. The cosmetic or therapeutic composition may include one or more of cosmetic or pharmaceutical...
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5569677 |
Diphenyl-2-propenoates for treating diseases associated with leukotriene B4
This invention relates to a compound of formula I ##STR1## where the several groups are defined herein. These compounds are leukotriene antagonists and as such can be used in treating various...
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5563164 |
Phospholipase A.sub.2 inhibitors
This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of...
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5561159 |
Method of treating wrinkles using tropic acid
A method for visibly reducing a facial wrinkle by topically applying to the wrinkle tropic acid or a topically effective salt thereof.
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5556866 |
Hair restorer and its preparation
A hair restorer which comprises a carrier and an effective amount of one or more compounds selected from the group consisting of 3-[4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]-2-propenoic acid,...
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5556882 |
Methods of treating wrinkles using benzilic acid
A method for visibly reducing a facial wrinkle by topically applying to the wrinkle benzilic acid or a topically effective salt thereof.
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5550145 |
Potentiation of antimicrobial effects
An antimicrobial composition comprising an antimicrobially effective amount of a combination of: A) a monoglyceride of lauric acid, a monoglyceride of monomyristic acid or a mixture of these...
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5541227 |
Ibuprofen-containing medicament
An ibuprofen-containing medicament which contains ibuprofen only in the (S)-(+)-form is disclosed. (S)-(+)-ibuprofen is more than twice as active as the racemate which has until now been used in...
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5534548 |
Method of treating preeclampsia
Straight-chain alkanoic acids, substituted at the Ω-carbon atom by a substituted phenyl, naphthyl, furyl, or thienyl group and by a substituted 1,4-benzoquinon-2-yl group are effective in the...
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5527827 |
Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis
Compounds having the Formula I: R 1 R 2 C(OR 3 )--Ar 1 --X--Ar 2 --C(Ar 3 )CHCO 2 H I are inhibitors of leukotriene biosynthesis. These compounds are useful as...
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5516803 |
Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
This invention relates to a composition comprising a tramadol material and a nonsteroidal antiinflammatory drug, and its use. The compositions are pharmacologically useful in treating pain and...
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5512596 |
Aromatic compounds
A composition comprising a compound of the formula: ##STR1## wherein: X is H or OH; Y is a group capable of hydrogen bonding to amino, guanidino, or imidazole function, or a group comprising an...
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5510385 |
Pharmaceutical compositions containing the salts of S(+)-2-(4-isobutylphenyl)propionic acid with basic aminoacids
A pharmaceutical composition for oral use containing the salt of S(+)-2-(4-isobutylphenyl)propionic acid with a basic aminoacid selected between L-arginine and L-lysine is described.
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5492687 |
Compositions of iodophenoxy alkylene ethers and pharmaceutically acceptable clays for visualization of the gastrointestinal tract
Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising iodophenoxy alkylene ethers and pharmaceutically acceptable clays in a...
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5490992 |
Disinfectant composition
The present invention is generally related to a product and a process to reduce the microbial contamination of processed meat and is particularly related to a product and a process to disinfect...
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5482973 |
Suppository preparation
A suppository comprising pranoprofen is disclosed. The suppository has analgesic or anti-inflammatory effects. Since pranoprofen is administered away from gastrointestinal tracts, application of...
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5478857 |
Use of PLA.sub.2 inhibitors as treatment for alzheimer's disease
This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of...
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5475034 |
Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
Novel ester and amide derivatives of 3-benzoylphenylacetic acid are disclosed. The use of these novel derivatives and certain known derivatives in topically administrable compositions for the...
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5474989 |
Drug composition
The present invention relates to a drug composition in which the solubility and the dissolution rate of a drug having low water solubility are improved by incoroprating therein a low molecular...
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5468482 |
Palatable orally administered liquid medicaments for relief of discomfort and flavoring combinations therefor
A liquid composition for the relief of discomfort, in particular, premenstrual and menstrual discomfort including, as active pharmaceutical agents, an effective amount of one or more of an...
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5468502 |
Ibuprofen enhancing solvent system
Solvent systems for enhancing the solubility of ibuprofen for encapsulation into soft gelatin capsules is provided by the addition of ammonium acetate to the solvent system.
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5466435 |
Compositions of iodophenoxy alkylene ethers and cellulose derivatives for visualization of the gastrointestinal tract
Disclosed are contrast agents of the formula ##STR1## wherein Z is H, halo, C 1 -C 20 alkyl, cycloalkyl, lower alkoxy, alkoxycarbonyl, cyano, where the alkyl and cycloalkyl groups can be...
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5462954 |
Substituted phenyl phenol leukotriene antagonists
Antagonists having a substituted phenyl phenol or a substituted phenolic biphenyl structure, and various derivatives thereof, are specific leukotriene antagonists. Their structures, use and...
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5459157 |
Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug
A pharmaceutical aqueous solution for ophthalmic use comprising a nonsteroidal anti-inflammatory drug, having a carboxylic group, a decongestant drug and a mixture of a polysorbate and a poloxamer.
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5459135 |
Composition comprising indomethacin [non-steroidal anti-inflammatory agent] and effectively non-antibacterial tetracycline to reduce bone loss
A method for treating mammals suffering from rheumatoid arthritis and other tissue-destructive (chronic inflammatory or other) conditions associated with excess metalloproteinase activity...
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5453443 |
Bis(aryloxy)alkanes as inhibitors of phospholipase A.sub.2 enzymes
Compounds having the formula I: ##STR1## are inhibitors of the PLA 2 s enzymes. These compounds are useful as anti-allergic, anti-asthmatic, they are also useful in treating various inflammatory...
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5447954 |
Phenylderivate as inhibitors of ATP citrate lyase
Compounds of the formula ##STR1## where the substituents are defined in the specification useful in the treatment of hyperlipidemia.
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