|
Match
|
Document |
Document Title |
|
|
5939455 |
Therapeutic augmentation of oxyalkylene diesters and butyric acid derivatives
This invention provides a method of augmenting the therapeutic activity of an oxyalkylene-containing compound, butyric acid, a butyric acid salt or butyric acid derivative by administering an...
|
|
|
5932618 |
Anti-viral agents and methods relating to the use thereof
Compounds having utility as anti-viral agents in general and, more specifically, to methods for treating a viral condition in an animal are disclosed. The compounds are naphthalene derivatives, and...
|
|
|
5932229 |
Oxa diacids and related compounds for treating skin conditions
Described are the use of compounds of Formula (I), depicted below, as active principals for treating skin conditions; compositions containing these compounds; and methods of treating skin...
|
|
|
5932617 |
Wound-treating composition and method
A cell-proliferation promoting and wound-healing composition and method utilizing a compound or salt of Formula (I), ##STR1## in which R 1 is (CH 2 ) n CH 3 wherein n is 0 to about 10; Formula...
|
|
|
5929120 |
Guainidino, formamidino, amino and related compounds for inhibiting osteoclast-mediated bone resorption
Compounds of the following general structure X--Y--Z-Aryl-A--B, ##STR1## which inhibit osteoclast mediated bone resorption.
|
|
|
5886022 |
Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have...
|
|
|
5886043 |
Substituted 4-biarylbutyric acid derivatives as matrix metalloprotease inhibitors
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have...
|
|
|
5883124 |
Compositions and methods for treating and preventing pathologies including cancer
Compositions and methods of treating various disorders by administering a therapeutically effective amount of phenylacetate or pharmaceutically acceptable derivatives thereof or derivatives thereof...
|
|
|
5883129 |
Hydroxylated anthranilic acid derivatives
The present invention relates to novel derivatives of 3-hydroxyanthranilic acid, 3-HANA, of the general formula I ##STR1## wherein R 1 and R 2 are the same or different and selected from H and...
|
|
|
5877213 |
Compositions and methods for therapy and prevention of cancer, AIDS, and anemia
Compositions and methods of treating anemia, cancer, AIDS, or severs β-chain hemoglobinopathies by administering a therapeutically effective amount of phenylacetate or pharmaceutically acceptable...
|
|
|
5872151 |
Immunopotentiatory agents and physiologically acceptable salts thereof
The present invention relates to the use of 4-(2-formyl-3-hydroxyphenoxymethyl) benzoic acid or physiologically acceptable salts thereof as an immunopotentiatory agent, compositions containing such...
|
|
|
5863926 |
4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds
The present invention relates to novel 4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating...
|
|
|
5863915 |
Substituted 4-arylbutyric acid derivatives as matrix metalloprotease
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have...
|
|
|
5861435 |
Method for preventing settlement of aquatic fouling organisms
A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to...
|
|
|
5861431 |
Incontinence treatment
The present invention provides a method of treating incontinence in a patient that has a bladder and a urethra. The urethra forms a lumen for draining the bladder. The method comprises the steps of...
|
|
|
5827500 |
Process for identifying RAR-receptor-antagonist compounds
The present invention relates to a process for identifying RAR-antagonist molecules, characterized in that it comprises the following steps: (i) a sufficient amount of an RAR-agonist molecule is...
|
|
|
5827852 |
Coated pharmaceutical compositions
Pharmaceutical composition suitable for coating comprising a composition for oral administration in unit dosage form wherein said composition has been coated with from about 0.01% to about 10% by...
|
|
|
5817684 |
Leukotriene antagonists for use in the treatment or inhibition of cerebral focal stroke
This invention provides methods for the treatment or prevention of cerebral focal ischemia which comprises administering to a mammal in need thereof an effective amount of a compound having...
|
|
|
5811459 |
Ortho substituted aromatic compounds useful as antagonists of the pain enhancing effects of E-type prostaglandins
The invention relates to compounds of the formula (I): ##STR1## wherein A, B and D are various ring systems such as phenyl, R 1 includes carboxy, R 3 is hydrogen or C 1 -4 alkyl and Z is a...
|
|
|
5798372 |
Method for preventing onset of restenosis after angioplasty employing a retinoid
A method is provided for preventing or reducing the risk of restenosis following angioplasty by administering a retinoid, such as an RAR-selective retinoid, e.g. the compound of the formula: ##STR1##
|
|
|
5798363 |
Use for tachykinin antagonists to treat emesis
The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel...
|
|
|
5792786 |
Non-steroidal anti-inflammatory fatty acid conjugates and their therapeutic use thereof
The present invention provides therapeutic conjugates which comprise a therapeutic compound bound to one to three acyl groups derived from fatty acids. The therapeutic compounds are preferably...
|
|
|
5789445 |
Method for topical treatment of scar tissue and related tissue reaction to trauma
Topical application to regions of tissue scarring of a composition comprising several ingredients commonly used in cosmetic products, such as benzoyl peroxide, leads to a reduction and a softening...
|
|
|
5789446 |
Therapeutic agent for treating joint diseases associated with arthritis
To provide a treating or ameliorating agent for joint diseases accompanied with arthritis, preferably, a rheumatoid arthritis or ameliorating agent, which exerts excellent pharmaceutical effects....
|
|
|
5773453 |
Methods for administration of antilipemic drugs
The present invention concerns methods for reducing cutaneous flushing in a patient to whom niacin is administered. According to the present method, two or more doses of a nonsteroidal...
|
|
|
5766613 |
Use of benzoic acid derivatives to stimulate the process of epidermal renewal
The present invention relates to the use of dihydroxybenzoic acid in or for the manufacture of a cosmetic or dermatological composition to stimulate the process of epidermal renewal. The invention...
|
|
|
5763468 |
Disinfectant or antiseptic composition comprising at least one terpene alcohol and at least one bactericidal acidic surfactant, and use of such a mixture
A quaternary-ammonium-free composition having bactericidal activity for both Gram positive and Gram negative bacteria, and including (i) at least one terpene alcohol and (ii) at least one...
|
|
|
5750515 |
Cancer metastasis inhibitor
The present invention relates to a cancer metastasis inhibitor comprising a benzoic acid derivative as an active ingredient represented by the formula (I) ##STR1## wherein R 1 , R 2 , R 3 and R 4 ...
|
|
|
5746998 |
Targeted co-polymers for radiographic imaging
A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic...
|
|
|
5736536 |
Method for treating vascular leak syndrome
A novel method for preventing, stabilizing or causing regression of vascular leak syndrome is disclosed. The method comprises administering to a patient in need thereof a compound selected from the...
|
|
|
5733539 |
Bait for fishes and shellfishes
The invention discloses a bait for fishes and shellfishes characterized in that the bait comprises a matrix material containing a microorganically fermented product of a plant residue obtained by...
|
|
|
5726180 |
Stabilized solid pharmaceutical preparation and method of producing the same
To stabilize the active ingredients, a caffeine is incorporated into a solid pharmaceutical preparation comprising a dextromethorphan and a phenylpropanolamine. The pharmaceutical preparation may...
|
|
|
5726201 |
Gemfibrozil containing pharmaceutical compositions
The invention relates to oral solid pharmaceutical composition containing as active ingredient gemfibrozil and conventional pharmaceutical auxiliary agents comprising as surfactant...
|
|
|
5719151 |
Substituted benzene compounds
Phthalazinedione compounds and pharmaceutical compositions are described. The compositions are useful in treating human or animal patients to alleviate or cure disease or disease symptoms caused by...
|
|
|
5714142 |
Method and compositions for increasing the serum half-life of pharmacologically active agents by binding to transthyretin-selective ligands
Compositions and methods are provided for increasing the serum half-life of a pharmacologically active agent. The novel compositions are covalent conjugates of the selected pharmacologically active...
|
|
|
5710178 |
Compositions and methods for therapy and prevention of pathologies including cancer, AIDS, and anemia
Compositions and methods of treating anemia, cancer, AIDS, or severe β-chain hemoglobinopathies by administering a therapeutically effective amount of phenylacetate or pharmaceutically acceptable...
|
|
|
5710179 |
Antitumor agent
An antitumor agent comprising as an effective ingredient 3- 4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl!-2-propenoic acid obtained from propolis and/or its physiologically acceptable salt(s). The...
|
|
|
5693312 |
Pharmaceutical composition having analgesic activity
Pharmaceutical compositions having analgesic activity containing (S)-2-(6-methoxy-2-naphthyl)-propionic acid as active ingredient and arginine, useful for the preparation of pharmaceutical forms...
|
|
|
5681856 |
Method of reducing focal ulcerative dermatitis (FUD) in poultry
Focal Ulcerative Dermatitis in poultry raised for consumption is prevented and treated by a method which includes the step of administering orally an effective level of aspirin over a prolonged...
|
|
|
5668182 |
Method of calming or sedating an animal with a hydroxy benzaldehyde compound
Various hydroxy benzaldehyde derivatives including Vanillin, a natural product derived from the vanilla bean that is commonly used as a flavoring agent, is administered by injection (i.v., i.m.,...
|
|
|
5654331 |
Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics
Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R 1 is --CH 3 , --CH 2 OH, --COR 8 or --CH 2 OCOR 9 , R 8 is H, OH, --OR 10 ,...
|
|
|
5652266 |
Cosmetic or dermatological compositions
A cosmetic or dermatological composition containing a skin enhancing agent consisting essentially of a) at least one α-hydroxy acid, b) salicylic acid or esters thereof and c) at least one...
|
|
|
5646184 |
Preparation for external application to the skin and novel benzoic acid derivatives
Disclosed is a preparation for external application to the skin characterized by containing at least one of benzoic acid derivatives represented by formula (I) or pharmacologically acceptable salts...
|
|
|
5646131 |
Method for solubilizing drugs using cyclodextrins and carboxylic acids
A method for enhancing the solubilization and/or complexation of a drug which is insoluble or sparingly soluble in water with cyclodextrin, comprising combining the drug with cyclodextrin together...
|
|
|
5643949 |
Phenyl alpha acyloxyalkanoic acids, derivatives and their therapeutic use
Therapeutic as well as preventative measures to improve the cosmetic conditions or to alleviate the symptoms of dermatologic disorders with phenyl alpha acyloxyalkanoic acids and derivatives is...
|
|
|
5637617 |
Methods for use of GABA.sub.a receptor GABAergic compounds
A method is disclosed for potentiating mammalian GABA A receptor responses to GABA. The receptor responses are potentiated according to the invention by contacting GABA A receptors with GABA and...
|
|
|
5618516 |
Method of reducing subcutaneous inflammation by the topical application of a hydrophilic pharmaceutical composition containing ketoprofen lysine salt
A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution...
|
|
|
5614171 |
Hydrophilic pharmaceutical composition containing ketoprofen lysine salt for topical use
A hydrophile pharmaceutical composition in the form of foam is described which contains as active ingredient Ketoprofen lysine salt having a concentration between 10 and 20% p/volume of solution...
|
|
|
5604259 |
Treatment of bone loss with ibuprofen or flurbiprofen
This invention relates to the use of flurbiprofen and ibuprofen, their pharmaceutically acceptable salts and esters in a method of increasing bone mass and the treatment and prevention of bone mass...
|
|
|
5599817 |
Xanthine derivatives as diuretic agents
A method for stimulating diuresis comprising administering a composition comprising 8-(3-oxocyclopentyl)-1,3-di-n-propyl-7H-purine-2,6-dione and, optionally, a loop diuretic, is disclosed.
|