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7449315 Bifunctional energy-reversible acyl-compositions  
Energy-reversible acyl conjugates, intermediates, and related compositions are disclosed. In preferred aspects, examples of such compositions include:
7399789 Bone targeting compounds for delivering agents to bone for interaction therewith  
The present invention relates to compounds of the formula or pharmaceutically acceptable salts thereof, useful for delivering agents having the capacity to diagnose, treat or prevent bone injury or...
7390504 HDL-boosting combination therapy complexes  
A pharmaceutical composition including therapeutically effective amounts of at least one HMG-CoA reductase inhibitor present as a dyhydroxyacid salt and at least one additional therapeutic agent.
7365085 Compounds and methods  
Disclosed is a compound having the formula: pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as...
7342044 Preservative blends containing quaternary ammonium compounds  
The present invention provides a biocidal composition comprising a synergistic mixture of certain quaternary ammonium biocides and one or more ketone acids, aromatic carboxylic acids, salts...
7318930 Control methods for boring bark beetles  
A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described....
7314888 Compounds and medicinal use thereof  
A compound or a salt thereof having the atom corresponding to N3 and the two or more atoms selected from N1, N2, N4 and N5, said atoms constitute the pharmacophore represented by the following...
7309720 2-ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders  
A compound of formula (I) wherein T represents O, S or NR and wherein R represents a H, a C1-6alkyl group or a phenyl C1-6alkyl group and pharmaceutically acceptable salts thereof, processes for...
RE39916 Compounds that modulate PPAR activity and methods for their preparation  
This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the...
7262180 Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye  
The present invention relates to compositions comprising telmesteine, glycyrrhetinic acid, and a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory...
7262217 Compositions with anisic acid and glycerides  
This invention relates to formulations containing a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride and to the use of such combinations as a...
7232821 (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives  
Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, R1, R2, Rx, R8, R9 and n are as defined in the specification, a process for the preparation of such...
7220780 Naaladase inhibitors for treating retinal disorders and glaucoma  
The present invention relates to pharmaceutical compositions and methods for treating a retinal disorder or glaucoma using NAALADase inhibitors.
7214712 Isophthalic acid derivatives as matrix metalloproteinase inhibitors  
Selective MMP-13 inhibitors are isophthalic acid derivatives of the formula wherein: R1, R2, and R3 independently are hydrogen, halo, hydroxy, C1–C6 alkyl, C1–C6 alkoxy, C2–C6 alkenyl, C2–C6...
7208520 Crystals of hydroxynorephedrine derivative  
The present invention provides ethyl (−)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-meth ylethyl]amino]ethyl]-2,5-dimethylphenoxy]acetate hydrochloride, crystalline forms thereof and p...
7192601 Antimicrobial and sporicidal composition  
Germicidal compositions with enhanced activity towards killing microbiological spores and vetgetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric...
7169810 Guanidine and amidine acid derivatives and analogs and methods of using the same  
The present invention releates to certain novel guanidine or amidine acid derivatives and analogs, to a process for preparing such compounds, having the utility in clinical conditions associated...
7151117 Concentrated X-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions  
The present application is directed to the use of X-ray contrast media that act as universal antigens that are labeled herein as “pseudoantigens.” X-ray contrast media have the potential to exi...
7132452 Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection  
The present invention provides a topical formulation containing NSAID, particularly diclofenac. The topical formulation is particularly useful for alleviating pain/inflammation associated with...
7122579 Eye treatments using synthetic thyroid hormone compositions  
The present invention involves the discovery that synthetic thyroid hormones can be used as compositions to reduce intraocular pressure in vivo. Methods of screening synthetic thyroid hormones for...
7119246 Method of treating acne  
This invention relates to a method for the treatment of acne that comprises applying a fluid comprising a polyalkylene carbonate over the area affected by acne and penetrating pores within the...
7094431 Method of healing skin wounds in mammals and a composition therefor  
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
7087644 Derivatives of dicarboxylic acid having pharmaceutical properties  
The invention relates to compounds of formula (I) as well as the salts and stereoisomers thereof wherein the several variable groups are as defined in the specification and claims. Processes for...
7078400 20-HETE synthase inhibitor  
The present invention relates to an inhibitor for production of 20-hydroxyeicosatetraenoic acid, comprising, as an effective ingredient, specific hydroxyformamidine derivatives or...
7064124 NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient  
A NF-κB inhibitor represented by the following formula (I) is provided:
7060730 Rapidly absorbed liquid compositions  
The present invention provides a method which provides for a faster absorption of pharmaceutically acceptable amines. The method provides a pharmaceutically acceptable amine in combination with a...
7048918 Insect bait  
Disclosed are insect baits for attracting insects such as ants, flies and cockroaches. The baits include amino acids and a sugar. The baits can be combined with an insect toxicant to effectively...
7029706 Composition for the treatment of cutaneous mycosis  
The inventions relates to the use of silica in the formulation of antifungal composition for the treatment of cutaneous mycoses, and method to manufacture an antifungal powder with boric acid and...
7030162 Treatment of migraine headache  
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
7030133 Inhibitors of formation of advanced glycation endproducts (AGEs)  
The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is...
7025985 Dihydroxyphenyl compounds and glucoside compounds thereof  
The present invention is a compound represented by the following formula (1) or (2): where one of R1 and R2 is hydrogen and the other one is hydrogen or glucose residue. The compound is effective...
7005451 Agent for repelling and inactivating pathogenic organisms of plants  
The invention relates to disinfecting agents for combating and inactivating phytopathogenic organisms for use on plants and in their environment. The agents are based on a mixture of anionic,...
6998144 Method of improving sweetness delivery of sucralose  
This invention provides a method of improving the sweetness delivery profile of a sucralose-containing ingestible composition, which comprises incorporating therein DHB at a DHB:sucralose weight...
6995190 Method and treatment with ketoprofen solution  
A readily water-soluble ingestible form of ketoprofen is provided by the reaction of ketoprofen and any edible weak base to yield a palatable, stable, safe pharmaceutical solution for mass...
6992109 Method for the treatment of incontinence  
The instant invention is a method of using certain analogs of glutamic acid and gamma-aminobutyric acid to treat incontinence.
6992093 Method of inhibiting lipofibroblast to myofibroblast transdifferentiation  
Methods of inhibiting lipofibroblast to myofibroblast transdifferentiation in a mammal are disclosed comprising administering a PPAR gamma ligand when said mammal is exposed to a hyperoxic condition.
6991806 Pharmaceutical compositions comprising ibuprofen and domperidone  
A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament; (ii) a domperidone medicament and (iii) a carrier material characterized in that the carrier material is...
6984645 Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein  
Compounds that are dual aP2/k-FABP inhibitors are provided having the formula wherein A, B, X, Y, R1, R2 and R3 are as described herein. A method is also provided for treating diabetes and related...
6984389 Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality  
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a n...
6982097 Biocidal compositions and methods of using same  
This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using...
6974833 Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration  
Methods for the treatment of diseases or pathological states related to the degradation of the extracellular matrix, such as degenerative diseases atheriosclerosis, cancer, infection or other...
6962714 Critical fluid antimicrobial compositions and their use and generation  
The present invention relates to antimicrobial compositions including a critical, near critical, or supercritical (densified) fluid and an antimicrobial agent, to methods of forming these...
6962774 Method for dry-preserving multicellular organism tissue at ordinary temperatures  
A tissue of a multicellular organism is gradually dried during cultivation. After the tissue has been completely dehydrated, water is added to the tissue for its recovery. The tissue of the...
6943192 Treatment regimen for administration of phenylacetylglutamine, phenylacetylisoglutamine, and/or phenylacetate  
Herein is disclosed a method of treating neoplastic disease, including cancer, comprising administering a pharmaceutical composition, the pharmaceutical composition comprising a highly concentrated...
6936638 Ligands of adenine nucleotide translocase (ANT) and compositions and methods related thereto  
Compounds which have utility in the treatment of conditions associated with altered mitochondrial function. The compounds have the following structure (I): including stereoisomers, prodrugs, and...
6936266 Desquamation/epidermal renewal of the skin and/or combating skin aging  
Cinnamic acid and derivatives thereof are well suited for promoting desquamation and/or stimulating epidermal renewal and/or combating intrinsic/extrinsic aging of the skin of a human subject in...
6936636 5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity  
Compounds of the formula: where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of...
6936597 Prodrugs of anticancer agents employing substituted aromatic acids  
Polymeric prodrugs of the formula: wherein B is selected from the group consisting of OH, leaving groups, residues of amine-containing moieties and a residues of hydroxyl-containing moieties;Y1 is...
6932966 Topically applied reconstituted ocean water mixture and method of producing and using the mixture  
A skin treatment mixture for treating pierced skin such as that resulting from a body piercing procedure includes sea salt, lysozyme and reconstituted ocean water. The reconstituted ocean water...
6919325 Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts  
Pharmaceutical compositions and kits comprising: (a) a tiotropium salt; and(b) a salmeterol salt having a solubility in water of 0.1 mg/mL or less, processes for preparing them, and their use in...