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4191765 |
1-Aryloxy-2-hydroxy-3-aminopropanes
Compounds of formula I ##STR1## wherein R 1 and R 1 ' are identical or different and represent hydrogen, an alkyl radical or alkoxy radical having 1-4 carbon atoms, the allyl group, a halogen atom...
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4187317 |
Sunscreen and erythema treating with N-benzylidene anilenes
Compositions for treating radiation induced erythemas and for protecting the human skin against the harmful effects of sunlight, containing as the active ingredient N-benzylideneaniline and its...
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4186210 |
Method of treatment with glycinamides
L- and DL- Phenylglycines of the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl and R 1 is NH 2 , OH or completes a carboxylic ester group, useful...
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4185115 |
Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives
Novel para-[aryl(alkyl or alkenyl)amino]benzoic acids, esters, pharmaceutically acceptable salts and pharmaceutical compositions thereof and a method of lowering serum lipid levels in mammals...
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4185116 |
L- and DL- Phenylglycines to treat diseases or conditions attributable to reduced carbohydrate metabolism
L- and DL- Phenylglycines of the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl and R 1 is NH 2 , OH or completes a carboxylic ester group, useful...
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4182774 |
Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof
Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: ##STR1## wherein R is hydrogen or lower alkyl, R 1 is hydrogen, lower-alkyl, sodium or potassium, R 2 ...
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4182776 |
Method of treating lipidemia with aryloxyalkylaminobenzoic acids and esters
Aryloxyalkylaminobenzoic acids and esters as hypolipemic compounds.
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4179515 |
Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition
Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X 4 and X 5 are hydrogen or lower alkyl,...
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4178385 |
Method for treating hyperlipidemia in primates using 4-((4-fluorophenylmethyl)amino)benzoic acid
A method for treating hyperlipidemia in primates using the compound 4-((4-fluorophenylmethyl)amino)benzoic acid, a pharmaceutically-acceptable salt or an ester thereof.
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4176194 |
Oxyalkanoic acid derivatives
The invention concerns novel diarylmethyleneamino-oxyalkanoic acid derivatives which possess useful analgesic properties in warm-blooded animals. In addition certain of the derivatives also possess...
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4173649 |
5-Phenyl-2,4-pentadien-1-amines and method for inhibiting prostaglandin dehydrogenase
5-Phenyl-2,4-pentadien-1-amines and salts thereof are provided having the structure ##STR1## wherein R 1 is hydrogen, lower alkyl, lower alkoxy, hydroxy, lower alkanoyloxy, nitro, cyano, amino,...
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4166128 |
Substituted phenylglycolic acid and its pharmaceutically acceptable esters and salts, and processes for preparing the same
Novel substituted phenylglycolic acid represented by the formula ##STR1## AND ITS PHARMACEUTICALLY ACCEPTABLE NON-TOXIC ESTERS AND SALTS HAVE POTENT ANALGESIC, ANTI-INFLAMMATORY AND ANTIPYRETIC...
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4165382 |
Method of pharmacologically treating schizophrenia with alpha-methyl-para-tyrosine
A method of pharmacologically treating schizophrenia which method comprises administering to a human being a therapeutically effective amount of alpha-methyl-para-tyrosine and an alkalinizing...
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4163060 |
Aralkylamino carboxylic acids and derivatives having spasmolytic activity
Novel substituted aromatic aliphatic amino carboxylic acids containing a tertiary nitrogen atom such as 3-[N-ethyl-[1-methyl-2-(4-methoxyphenyl)] ethylamino] -1-propane carboxylic acid ethyl ester...
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4156013 |
Method for treating patients suffering from anxiety neurosis and anxietylike neurosis, and alcoholism
Patients suffering from anxiety neurosis and anxietylike neurosis often accompanied by alcoholism are treated by administration of medicine containing a β-(p-halogen phenyl)-Γ-aminobutyric acid...
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4154850 |
Certain di-(substituted phenoxy) alkanes and hypolipidaemic use thereof
A class of di-(substituted phenoxy) alkanes having from 7 to 25 carbon atoms in the alkane moiety have hypolipidaemic activity.
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4154823 |
Skin treatment compositions and methods of using same
A skin treatment composition or formulation comprising para-aminobenzoic acid, calcium-d-pantothenate, and a tocopherol compound, and desirably a gelling agent, is disclosed, along with methods of...
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4148920 |
Therapeutic L- and DL- phenylglycines to treat diseases or disorders of reduced blood flow or oxygen availability
L- and DL- Phenylglycines of the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R is hydrogen or methyl and R 1 is NH 2 , OH or completes a carboxylic ester group, useful...
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RE29892 |
Composition and method of treating dopamine deficiency in brain tissue
The dopamine content in brain tissue of animals is increased by administering to the animal L-dopa or its salts in combination with L-α-hydrazino-α-lower alkyl-3,4-dihydroxyphenyl propionic acid...
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4130658 |
Novel phenethylamines
Novel phenethylamines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, acyl of an aliphatic carboxylic acid of 2 to 6 carbon atoms and benzoyl and Y is selected...
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4126684 |
4-Amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
4-Amino-3-p-halophenylbutyric acids, acyl derivatives, esters and/or salts thereof reduce addiction liability, particularly that of narcotics, or the withdrawal symptoms observed after interruption...
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4109013 |
Substituted propanol-(2) derivatives of hydroxamic acids and the use thereof as hypolipemic drugs
New 1,3-disubstituted propanol-(2) derivatives and their nicotinic acid esters of the general formula ##STR1## and their therapeutically acceptable salts, processes for preparing the same and the...
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4107331 |
Zinc chelating fungicidal composition
Fungi requiring zinc ions are killed by applying to the fungi compounds capable of chelating zinc in concentrations of at least 3.5%. The invention is particularly effective in treating candida...
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4105790 |
α-Amino ketone derivatives
The invention concerns α-aminoacyl derivatives of phenyl-, phenoxy-, thiophenoxy- and phenylsulphinylalkanoic acids together with their amides, esters and pharmaceutically acceptable salts;...
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4104368 |
Composition and method for protecting skin and hair
A composition which provides both a conditioning and sun-screening effect for hair and skin wherein the active agent comprises a salt of certain long chain cationic bases and certain acidic...
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4093648 |
Therapeutically active benzoic acid derivatives and a process for preparing them
Therapeutically active 2- and 3-substituted benzoic acid derivatives having the general formula ##STR1## wherein X is OH, NH 2 or an anilino group having the phenyl ring unsubstituted or...
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4092426 |
Novel aminobenzoic acid derivatives, process for preparing the same and pharmaceutical composition containing the same
An aminobenzoic acid derivative represented by the formula ##STR1## wherein R 1 , R 2 and R 3 are defined hereinbelow, which has excellent activity for improving liver function and for...
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4084000 |
Method of treating schizophrenia
A method for treating schizophrenia and a method and composition for potentiating the beneficial effects and reducing the side effects of neuroleptic drugs. Schizophrenia is treated with a...
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4046915 |
Process for treating elevated platelet adhesiveness
A process for inhibiting platelet aggregation by the addition of a member selected from the group consisting of a compound of the formula: ##STR1## wherein is cyclohexane or phenyl; Y is...
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4045576 |
Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds
Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: ##STR1## wherein R is hydrogen or lower alkyl, R 1 is hydrogen, lower-alkyl, sodium or potassium, R 2 ...
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4035507 |
Novel, transient pro-drug forms of L-DOPA to treat Parkinson's disease
There is provided, novel, transient pro-drug forms of L-DOPA (3,4-dihydroxy-L-phenylalanine), having the formula: ##STR1## wherein R represents a hydrogen atom, an acyl group, ##STR2## group, a...
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4029815 |
Anti-diarrheal anthranilic acids
This invention relates to compositions of matter useful as anti-diarrheal agents and to the method of controlling and treating diarrhea in warm blooded animals. The active anti-diarrheal agents are...
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4024279 |
Treatment of dysmenorrhea and migraine symptoms
A pharmaceutical composition for the treatment of, or for the alleviation of primary dysmenorrhea, for the treatment of acute migraine and for attaining the relaxation of smooth muscle, and a...
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4022910 |
L-3-hydroxymethyltyrosine and salts thereof for lowering blood pressure
L-3-Hydroxymethyltyrosine and pharmaceutically acceptable salts thereof useful in lowering blood pressure and compositions thereof.
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4003990 |
Anti-inflammatory polymers, pharmaceutical compositions containing the same and process for producing said polymers
A polymer has on its macromolecular chains in the form of a lateral branching an anti-inflammator residue having a carboxylic acid function chemically linked to the macromolecular chains by an...
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3995058 |
Treatment of ethanol withdrawal symptoms with levodopa
Levodopa or a composition comprising levodopa and a peripheral dopa decarboxylase inhibitor prevents or suppresses ethanol withdrawal symptoms in individuals abstaining from ethanol in a...
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3991207 |
Combination therapy for Parkinson's disease
Substituted 1,2,3,4-tetrahydro-1-naphthylamines, or their acid addition salts, as potentiating agents in combination therapy with L-Dopa for control of the symptoms of Parkinson's disease....
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3989841 |
Method of using fluorene-2-acetic acid derivatives
Novel fluorene-2-acetic acid derivatives and methods for preparing these derivatives are provided. Inflammatory conditions may be treated by administering these novel compounds. Additionally, it...
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3976782 |
3-(2,5-Dihydroxyphenyl)-alanine as a cardiac stimulant
3-(2,5-Dihydroxyphenyl)-alanine, in its racemic form as well as the individual optical isomers thereof possess significant activity as cardiac stimulants. Various derivatives of the racemic mixture...
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3956504 |
Method of preventing thromboses
In order to render the vascular system stable against the formation of thromboses, daily or periodic doses of a salt of para amino benzoic acid are taken orally or are administered by injection to...
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3950536 |
N,N-Dichloro substituted aminocarboxylic acids as bactericides and fungicides
N-chloro nitrogen-containing carboxylic acids have been found to be useful as microbiocides in topical treatment of the skin and mucous membranes.
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3947579 |
Method and composition for potentiating neuroleptic drugs
A method and composition for potentiating the effects of neuroleptic drugs by administering to a human having a disorder normally treatable with a neuroleptic drug, a neuroleptic drug in...
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3931409 |
Composition and method for treatment of hyperuricemia
Trichloroamino(and acylamino)phenylalkanoic acids or esters, useful as uricosuric agents, are prepared by chlorination of the corresponding aminophenylalkanoic acids or esters, followed, if...
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3928588 |
Method of reducing the undesirable gastrointestinal effects of prostaglandin synthetase inhibitors
There is disclosed concomitant systemic administration of prostaglandins of the PGF β-type, for example, PGF 2 β, and a prostaglandin synthetase inhibitor, for example, indomethacin, aspirin, or...
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3924001 |
Hypolipidemic 4-(monoalkylamino)benzoic acid derivatives
4-(Monoalkylamino)benzoic acids and esters, pharmaceutically acceptable salts thereof, and a method for lowering serum lipids in mammals by administration of said acids, esters and salts; and...
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3920838 |
Amino acid therapy
The invention described herein is a method of treatment of patients during periods of severe negative caloric balance due to dysfunction or disuse of the gastro-intestinal tract for reasons such as...
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3917828 |
Method of reducing the undesirable gastraintestinal effects of prostaglandin synthetase inhibitors
There is disclosed concomitant systemic administration of prostaglandins of the PGF α-type, for example, PGF 2 α, and a prostaglandin synthetase inhibitor, for example, indomethacin, aspirin, or...
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3917832 |
Compositions comprising d-thyroxine and d-triiodothyronine
Pharmaceutical compositions comprising d-thyroxine and d-triiodothyronine are useful in the treatment of hyperlipidemias, especially hypercholesterolemias and hypertriglyceridemias.
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3911137 |
Process for preparing highly concentrated aqueous solution of a dopa compound
A highly concentrated aqueous solution of a dopa or tyrosine can be prepared by adding at least one water-soluble high molecular weight substance selected from the group consisting of methyl...
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3888993 |
Pharmaceutical composition containing amino alcohols derived from ortho-trans-hydroxycinnamic acids, their esters and their amides
Pharmaceutical compositions which contain as active principle a compound represented by the formula ##SPC1## In which R is an optionally substituted hydroxy, alkoxy or amino radical, R' is a...
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