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7619115 |
Ortho-substituted N'-benzylidene-(3-hydroxyphenyl)acethydrazides
Novel ortho-substituted N′-benzylidene-(3-hydroxyphenyl)acetohydrazides of the formula (I), in which R 1 -R 9 have the meanings indicated in claim 1 , are SGK inhibitors and can be used for the...
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7608641 |
Creatine oral supplementation using creatine hydrochloride salt
Creatine oral supplementation using creatine hydrochloride salt, that may be added to a liquid or other beverage, or may be also used as an additive to solid oral dosages, or as a supplement, and...
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7576132 |
Arginine silicate inositol complex and use thereof
A method for preventing and treating a variety of disease states and disorders is provided, comprising the administration of an arginine silicate inositol complex to an individual in the presence...
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7507766 |
Treatment of cancers
Carnitine and other muscle protectors are useful to prevent side effects of aplidine and aplidine analogues.
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7504118 |
Dietary supplements containing extracts of cinnamon and methods of using same to enhance creatine transport
Materials derived from cinnamon can be administered orally to humans or animals for the purpose of controlling blood glucose as well improving glucose tolerance. Controlling glucose metabolism is...
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7452916 |
Enhancement of vascular function by modulation of endogenous nitric oxide production or activity
Endothelial nitric oxide production is enhanced by administration of arginine or lysine as a dietary supplement. Enhanced nitric oxide production from arginine supplementation improves vascular...
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7419981 |
Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
The instant invention relates to a combination of an alpha-2-delta ligand and a PDEV inhibitor for use in therapy, particularly in the treatment of pain, particularly neuropathic pain. Particularly...
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7393825 |
Microdose therapy
Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7318930 |
Control methods for boring bark beetles
A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described....
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7285573 |
Use of creatine or creatine analogs for the treatment of diseases of the nervous system
The present invention relates to the use of creatine compounds including creatine, creatine phosphate or analogs of creatine, such as cyclocreatine, for treating diseases of the nervous system....
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7276535 |
Intratesticular injection of chemical sterilant
A low effective dose of a biologically acceptable chemical sterilant is injected into the dorsal cranial portion of a scrotal testis of a male animal for the purpose effecting sterilization of the...
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7241797 |
Method of increasing milk production
The invention relates generally to the use of pharmaceutical compositions to increase milk production alone or in combination with certain biological active ingredients. Specifically, the method...
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7226947 |
Use of creatine as a fat substitute
The invention relates to the use of creatine or creatine salts as a fat substitute to be given to breeding animals and feeder animals. The creatine or creatine salts are used as a substitute for...
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7202278 |
4-fluoro-N-indan-2-yl benzamide and its use as a pharmaceutical
A method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan- 2-yl benzamide according to...
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7202229 |
Aspirin formulation for cardiovascular health
The invention relates generally to an aspirin formulation which may comprise additional vitamins, minerals, herbs and supplements and methods for using the same for maintaining cardiovascular...
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7196065 |
Enteral formulation
A formulation for enteral administration to a patient is disclosed.
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7186754 |
Use of creatine or creatine compounds for skin preservation
The present invention relates to the use of creatine compounds such as, for example, creatine, creatine phosphate or analogs of creatine, such as creatine-pyruvate, creatine-ascorbate,...
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7169814 |
Guanidinium transport reagents and conjugates
Transport reagents and conjugates of therapeutic agents linked to transport reagents are described. In particular, the transport reagents have a plurality of guanidinium moieties that are either...
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7169768 |
Method of decreasing atherosclerosis and its complications
A method of decreasing atherosclerosis and its complications including but not limited to myocardial infarction, stroke and peripheral vascular disease wherein the method involves administering to...
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7135498 |
Nitric oxide donors for inducing neurogenesis
There is provided a method of promoting neurogenesis by administering a therapeutic amount of a nitric oxide donor compound to a patient in need of neurogenesis promotion. Also provided is a...
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7048918 |
Insect bait
Disclosed are insect baits for attracting insects such as ants, flies and cockroaches. The baits include amino acids and a sugar. The baits can be combined with an insect toxicant to effectively...
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7045550 |
Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical...
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7001922 |
Peptide deformylase activated prodrugs
The invention provides compounds and methods for using them to inhibit the growth of microorganism that expresses Peptide Deformylase, the compounds having the general formula:
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6995158 |
Pharmaceutical preparation containing at least folic acid or a folate and tetrahydrobiopterin (BH4) or derivatives thereof used for the treating or preventing cardiovascular or neurological disorders by modulation of the activity of nitric oxide synthase (NOS)
The invention relates to the uses of at least folic acid or a folate and tetrahydrobiopterin (BH 4 ) or derivative thereof for treating or preventing cardiovascular of neurological disorders by...
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6967219 |
Reversing or preventing premature vascular senescence
Premature vascular senescence is reversed or prevented in tissue or cells by contacting the tissue or cells with a hydroxyguanidine. This finds application in treatment of patients with a disorder...
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6964969 |
Composition and method for treating impaired or deteriorating neurological function
A nutritional supplement composition for normalizing impaired or deteriorating neurological function in humans is composed of: at least one agent which promotes synthesis of ATP and/or creatine...
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6951844 |
Phenyl naphthol ligands for thyroid hormone receptor
New thyroid receptor ligands are provided which have the general formula I
wherein R 1 is halogen, trifluoromethyl, substituted or unsubstituted aryl, substituted or unsubstituted C 1-6 ...
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6932985 |
Azide method and composition for controlling deleterious organisms
Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising azide and...
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6903136 |
Food supplements containing 4-hydroxyisoleucine and creatine
The present invention provides a dietary or food supplement for healthy humans that includes a combination of 4-hydroxyisoleucine and creatine, or nutraceutically acceptable derivatives of these...
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6900180 |
Pharmaceutical compositions for alleviating discomfort
The invention relates to products for complete nutrition of infants or diseased or elderly persons. The products are characterized by increased levels of folic acid, vitamin B6 and vitamin B12 or...
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6881424 |
Highly acidic metalated organic acid
A highly acidic metalated organic acid composition and its preparation. The acidic composition can be prepared by mixing a monovalent or polyvalent cation and an organic acid in the presence of a...
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6872751 |
Composition and method for augmenting or restoring the production of fetal protein in patient in need thereof
The present invention relates to methods for prevention and/or treatment of diseases or conditions caused by deficiency in the adult isoform of a given protein wherein said method comprises...
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6867235 |
Helianthrone derivatives as anti-cancer agents
Hypericin, helianthrone and derivatives thereof of general formula (I)
wherein the dotted line between positions 11 and 12 represent an optional C11-C12 bond; R is independently selected from...
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6844320 |
Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both,...
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6838095 |
Ionic silver complex
The invention relates to a substantially non-colloidal solution made by combining ingredients comprising (a) water; (b) a source of free silver ions; and (c) a substantially non-toxic,...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6830692 |
Amino acid composition for hemodialysis
The invention relates to a special amino acid mixture for hemodialysis as well as to the dialysis solution that can be prepared from the amino acid mixture. When the amino acid mixtures according...
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6827930 |
System for attracting fish
A sport fishing system having: a rod and reel, including fishing line; at least one fishing lure or natural bait; and a controlled released fish attractant for applying to the fishing lure or...
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6818669 |
Increasing cerebral bioavailability of drugs
A method and compositions are provided for increased cerebral bioavailability of blood-born compositions by administering the composition of interest while increasing brain NO levels. This increase...
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6812249 |
Process for preparing a 3-hydroxy-3-methylbutyrate amino acid salt and method of use
This invention relates to a process for synthesis and method of use of an effective amount of a 3-hydroxy-3-methylbutyrate (HMB) amino acid salt for the regulation athletic function in humans.
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6784209 |
Food supplement for increasing lean mass and strength
Food supplement compositions and their methods of use in increasing lean mass and/or muscle size and/or strength in individuals, particularly, athletes is described. The food supplements described...
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6784178 |
Pharmacotherapy for vascular dysfunction associated with deficient nitric oxide bioactivity
A patient with a disorder involving endothelial dysfunction associated with deficient nitric oxide bioactivity, e.g., coronary artery disease, atherosclerosis, hypertension, diabetes or...
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6747062 |
Regulation of wound healing by nitric oxide
The present invention provides methods and compositions for promoting healing of damaged tissue that result in an increased level of nitric oxide in the vicinity of the damaged tissue. Also...
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6746678 |
Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
This invention defines a novel method for treatment of several neurological diseases and pathophysiologically related symptomology, said diseases including peripheral neuropathies, secondary...
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6743823 |
Therapeutic methods relating to human carbamyl phosphate synthetase I polymorphism
Isolated polynucleotide molecules and peptides encoded by these molecules are used in the analysis of human carbamyl phosphate synthetase I phenotypes, as well as in diagnostic and therapeutic...
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6730331 |
Topically applied creatine containing composition
The present invention is a stable topical creatine application suitable for absorption directly through the skin into the underlying muscle without traveling through the blood system for the...
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6730329 |
Zinc containing compositions for anti-viral use
One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one...
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6727286 |
Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
The present invention provides a pharmaceutical composition comprising an aqueous solution of arginine and ibuprofen, wherein the molar ratio of arginine to ibuprofen is less than 1:1, as well as a...
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6727285 |
Use of D-arginine and/or L-arginine to protect the amino groups of biological substances from damage, inactivation, or modification by toxic carbonyls and/or dicarbonyls
A method of blocking dicarbonyls and carbonyls in vitro and in vivo includes using an effective quanity of an L- or D-arginine, substituted arginine, modified arginine or arginine-containing...
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