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7547450 |
Senior feline food
A feline pet food comprising a dietary level of protein and a supplemental amount of at least one amino acid in an amount sufficient to provide a feline lean body mass protection equivalent to...
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7504231 |
Method of alleviating chronic pain via peripheral inhibition of neurotransmitter synthesis
A composition having sustained pain-relieving properties such that the composition may be administered to a subject to alleviate chronic pain. The composition includes an effective amount of at...
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7420002 |
Amino acid conjugates providing for sustained systemic concentrations of GABA analogues
Compounds that provide for sustained systemic concentrations of GABA analogs following oral administration to animals are disclosed. Pharmaceutical compositions including, and methods using, such...
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7416740 |
Dry granulated product containing L-lysine as main component
Hydrochloric acid, sulfuric acid or an L-lysine solution having an equivalent ratio of anion/L-lysine higher than 0.95 is added to a raw material L-lysine solution having an equivalent ratio of...
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7414077 |
Therapeutic intervention to mimic the effect of caloric restriction
Methods are provided for promoting longevity and decreasing the incidence of ageing associated pathologies (e.g. cancer) by the administration of one or more of the following LFFA: linoleic, oleic,...
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7384979 |
Substituted amino acids as erythropoietin mimetics
This invention relates to a series of substitituted amino acids of Formula I
pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the...
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7374770 |
Topical composition for follicular delivery of an ornithine decarboxylase inhibitor
Polyethylene glycol ethers of alkyl alcohols having the general formula CH 3 (CH 2 ) x CH 2 (OCH 2 CH 2 ) n OH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7320988 |
Methods of lowering lipid levels in a mammal
This invention relates to methods for lowering lipid levels in mammals using compounds that inhibit advanced glycation endproducts (AGEs), LR-9, LR-74 and LR-90. These compounds, which inhibit...
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7318930 |
Control methods for boring bark beetles
A composition which causes adult boring bark beetles to discontinue boring, discontinue laying eggs and become disoriented and bore out of the tree or cease boring altogether and die is described....
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7273888 |
Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis
The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the...
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7244749 |
Compositions and methods for lowering plasma lipoprotein(a) and risk factors of cardiovascular diseases
The present invention provides compositions and methods for lowering plasma Lp(a) levels in humans. The present invention provides compositions and methods for lowering the risk factors for...
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7235542 |
Diagnosis and treatment of human kidney diseases
Kidney disease is diagnosed by measuring urinary catalytic iron in humans. Progressive kidney disease is treated by administering an iron chelator to humans. In particular, the progression of...
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7157497 |
Method of enhancing an ornithine-urea cycle in ruminant gut tissues to detoxify ammonia and increase local urea recycling to the rumen for microbial protein synthesis
A method of stimulating or enhancing an ornithine-urea cycle in ruminant gut tissues, which entails either feeding to a ruminant an effective amount of a ruminant feed or feed supplement containing...
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7129273 |
Dicreatine Malate
This invention relates to a novel compound, dicreatine malate, comprising approximately two moles of creatine cations per one mole of malate anion. The creatine salt of this invention has been...
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7101911 |
Tryptase inhibitors
Compounds of the formula I, in which M, A1, A2, K1 and K2 have the meanings given in the description are novel effective tryptase inhibitors.
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7087644 |
Derivatives of dicarboxylic acid having pharmaceutical properties
The invention relates to compounds of formula (I) as well as the salts and stereoisomers thereof
wherein the several variable groups are as defined in the specification and claims....
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7048918 |
Insect bait
Disclosed are insect baits for attracting insects such as ants, flies and cockroaches. The baits include amino acids and a sugar. The baits can be combined with an insect toxicant to effectively...
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7045532 |
ACE-2 modulating compounds and methods of use thereof
ACE-2 inhibitors for the treatment of body weight and related disorders are disclosed. ACE-2 inhibitors include peptides and small molecules. Examples of small molecule ACE-2 inhibitors include...
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7045550 |
Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical...
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7005450 |
2-amino-2-alkyl-4 hexenoic and hexynoic acid derivatives useful as nitric oxide synthase inhibitors
The present invention relates to 2-amino-2-alkyl-4 hexenoic and hexynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors.
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6987129 |
Compounds and methods for the treatment of urogenital disorders
The present invention provides methods for treating a variety of urogenital disorders, such as, for example, vaginismus, dyspareunia, vulvodynia (including vulvar vestibulitis), interstitial...
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6984661 |
Urea linker derivatives for use as PPAR modulators
The present invention is directed to compounds of the structural formula (I), and pharmaceutically acceptable salts, solvates and hydrates thereof: Formula I (a) R1, R2 and R6 are each...
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6974828 |
Propanoic acid derivatives as intergrin receptor antagonists
Novel propanoic acid derivatives are integrin receptor antagonists or inhibitors, in particular of the avb3 integrin receptor. The compounds of the invention are for instance useful for the...
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6974833 |
Synergistic compositions comprising ascobate and lysine for states related to extra cellular matrix degeneration
Methods for the treatment of diseases or pathological states related to the degradation of the extracellular matrix, such as degenerative diseases atheriosclerosis, cancer, infection or other...
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6967219 |
Reversing or preventing premature vascular senescence
Premature vascular senescence is reversed or prevented in tissue or cells by contacting the tissue or cells with a hydroxyguanidine. This finds application in treatment of patients with a disorder...
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6951889 |
2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors
The present invention relates to 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors.
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6949575 |
Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using aminoindane derivatives
The present invention provides compounds of Formula (I) and a method of treating Alzheimer's disease using a compound of Formula (I), wherein: R 1 and R 2 include alkyl and phenylalkyl; R 3 is...
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6936637 |
Prevention of apoptosis in non-cancerous cells
Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis....
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6932985 |
Azide method and composition for controlling deleterious organisms
Disclosed is both a method and composition for controlling deleterious organisms, such as insects, nematodes and weeds by applying a compound comprised of a liquid medium comprising azide and...
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6881424 |
Highly acidic metalated organic acid
A highly acidic metalated organic acid composition and its preparation. The acidic composition can be prepared by mixing a monovalent or polyvalent cation and an organic acid in the presence of a...
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6875764 |
Urea and thiourea compounds useful for treatment of coccidiosis
The present invention relates to novel compounds, pharmaceutical compositions containing the same as well as a method for treatment of parasitic disorders, wherein said compounds are administered....
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6852333 |
Agents and methods for promoting production gains in animals
The invention relates to compositions and methods for promoting production gains in animals, and of enhancing the efficacy of therapeutic agents. The gains are achieved through reduction in stress,...
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6844012 |
Use of selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing said treatment
The invention concerns the use of at least a molecule containing selenium, in an amount corresponding to a daily dose of about 2 to 40 mg, even 80 mg of atomic selenium equivalent, on its own or...
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6838095 |
Ionic silver complex
The invention relates to a substantially non-colloidal solution made by combining ingredients comprising (a) water; (b) a source of free silver ions; and (c) a substantially non-toxic,...
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6838472 |
Substituted urea retinoid agonists
The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6830692 |
Amino acid composition for hemodialysis
The invention relates to a special amino acid mixture for hemodialysis as well as to the dialysis solution that can be prepared from the amino acid mixture. When the amino acid mixtures according...
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6827930 |
System for attracting fish
A sport fishing system having: a rod and reel, including fishing line; at least one fishing lure or natural bait; and a controlled released fish attractant for applying to the fishing lure or...
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6797504 |
Inhibitors of serine protease activity of matriptase or MTSP1
The present invention provides compounds which inhibit serine protease activity of matriptase or MTSP1. Also provided are pharmaceutical compositions comprising those compounds and methods of using...
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6784209 |
Food supplement for increasing lean mass and strength
Food supplement compositions and their methods of use in increasing lean mass and/or muscle size and/or strength in individuals, particularly, athletes is described. The food supplements described...
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6730329 |
Zinc containing compositions for anti-viral use
One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one...
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6720304 |
Conjugate comprising a folic acid antagonist and a carrier
The invention relates to conjugates comprising a D-enantiomer of a folic acid antagonist and a carrier. Furthermore, the invention relates to the production of such conjugates as well as their use.
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6720306 |
Tetrapartate prodrugs
A compound of Formula I, providing tetrapartate prodrugs is provided wherein: L 1 is a bifunctional linking moiety; D is a moiety that is a leaving group, or a residue of a compound to be...
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6709679 |
Antineoplastic conjugates of transferin, albumin and polyethylene glycol
Conjugates of transferrin, albumin and polyethylence glycol consisting of native or thiolated transferrin or albumin or of polyethylene glycol (MW between approximately 5,000 and 20,0000) with at...
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6699904 |
PPAR agonists
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and...
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6696407 |
Huntington's disease treatment comprising administering aldose reductase inhibitors to increase striatal CNTF
The present invention provides methods of modulating neurotrophic factor-associated activity, especially CNTF-associated levels and activity, using aldose reductase inhibitors. These methods are...
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6696489 |
2-Methylpropionic acid derivatives and medicinal compositions containing the same
The present invention provides novel 2-methylpropionic acid derivatives represented by the general formula: (wherein R 1 represents a hydrogen atom, a lower alkyl group or an aralkyl group; R 2...
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6689392 |
Methods and compositions for controlling plant pathogen
A composition for controlling growth of pathological organisms on a plant, said composition comprises an effective amount of one or more of metal ion(s); one or more of chelating agent(s); and...
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6653322 |
Therapeutic combinations of RAR antagonists and RXR agonists and use thereof
The present invention provides compositions and methods for treating an animal, preferably a human, suffering from or predisposed to a physical disorder by administering an effective amount of a...
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