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5276053 |
Polycyclic amines useful as cerebrovascular agents
A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of...
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5272176 |
Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of...
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5260324 |
Composition containing D-cycloserine and D-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder
A composition is described for use in memory and learning enhancement or for treatment of a cognitive disorder or a psychotic disorder. This composition contains the compound D-cycloserine and...
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5254595 |
Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them
Aryloxypropanolaminotetralins with beta-antagonist activity of the formula ##STR1## wherein R is hydrogen, hydroxy or methoxy and Ar is an optionally substituted aromatic or heteroaromatic group,...
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5250569 |
Amino acid flavorings of aluminum astringent for oral use
Formulations of aluminum compounds with select amino acids such as glycine (aminoacetic acid) in a base material are described. The base material can be a sweetening agent such as a hard or soft...
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5248688 |
Method and substrate composition for treating atherosclerosis
A method and substrate composition for treating atherosclerosis are provided. The method involves parenterally administering the substrate composition as an aqueous solution to substantially lower...
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5244922 |
Methods for treating viral infections
The present invention provides methods for treating viral diseases in humans by administering to an afflicted host pharmaceutical compositions containing a therapeutically effective amount of a...
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5240930 |
Pharmaceutical compositions for treatment of depression and low blood pressure
A pharmaceutical composition which comprises a mixture of an alpha-2 adrenoceptor antagonist, preferably idazoxan, or a pharmaceutically acceptable salt thereof, and either a catecholamine...
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5225440 |
Attenuation of the opioid withdrawal syndrome by inhibitors of nitric oxide synthase
A method of attenuating the symptoms of opioid withdrawal in a human or animal subject comprises administering to the subject an effective opioid withdrawal symptom attenuating amount of an...
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5217994 |
Method of inhibiting osteoclast-mediated bone resorption by administration of aminoalkyl-substituted phenyl derivatives
Compounds of the general formula ##STR1## and the pharmaceutically acceptable salts thereof wherein n is an integer of from 0 to 6; Y is CH 2 , O, SO 2 , --CONH--, --NHCO--, or ##STR2## R 1 ...
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5211938 |
Method of detection of malignant and non-malignant lesions by photochemotherapy of protoporphyrin IX percursors
A method of detecting and treating malignant and nonmalignant tissue abnormalities and lesions of the skin, conjunctives, respiratory, digestive and vaginal mucosa; endometrium and urothelium in...
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5208260 |
Vinyl Glycine derivatives for memory and learning enhancement or treatment of a cognitive disorder
A class of vinyl glycine derivatives is described for use in memory and learning enhancement or for treatment of a cognitive disorder. The vinyl glycine derivatives of particular interest are...
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5206269 |
Highly concentrated amino acid solution
The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain...
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5206022 |
Insect repellent compositions
Liquefiable powder compositions are disclosed for the delivery of topical insect repellents. In particular, microporous cellulosic powders, such as cellulose acetates or nitrates, are disclosed as...
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5200428 |
Agent for the TSH suppression and treatment of struma
The agent for TSH suppression and for treatment of struma contains a therapeutically effective dose of 3,5-diiodo-L-thyronine and conventional galenic auxiliary materials.
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5188834 |
Method of preparing a biological implantation material
Method of preparing a fixed biological implantation material in which an implantation material is fixed with an aldehyde and the excess aldehyde is bound by an aminodicarboxylic acid in an acidic...
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5189064 |
Treatment of cocaine addiction
Cocaine addiction is treated by administration of an endorphinase or enkephalinase inhibitor, and optionally, a dopamine precursor, or a serotonin precursor, a GABA precursor, or an endorphin or...
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H001139 |
Combination of a calcium channel blocker and thromboxane A.sub.2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination
A method is provided for treating ischemia in a mammalian species by administering a combination of a calcium channel blocker such as diltiazem, SQ 31,765 or SQ 32,324 and a thromoboxane A 2 ...
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5179080 |
Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease
Methods of treating malnutrition associated with chronic lung diseases comprising the administration of metabolically active peptides in an amount sufficient to increase circulating somatomedin C...
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5162371 |
Method for treating inflammation
A method for treating inflammation in a patient which comprises administering to the patient a therapeutically effective amount of a compound of the formula: ##STR1## wherein A and R 1 -R 6 are...
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5162353 |
Carbacyclins, processes for their preparation, and their use as medicinal agents
The invention relates to carbacyclin derivatives with general formula I: ##STR1## in which Y 1 stands for the radical --CH 2 --X--(CH 2 ) n --R 1 or the radical ##STR2## n, 1 or 3, R 1 , the...
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5162369 |
Composition and method for enhancing the immune system in warm-blooded animals exhibiting symptoms of antigenic morbidity
A method for maintaining the immune system of a warm-blooded animal afflicted with a form of antigenic morbidity exacerbated by intestinal malabsorption of minerals is disclosed. Minerals selected...
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5158976 |
Controlling glutamine/glutamate related neuronal injury
A method of inhibiting neuronal injury or death in a human patient comprising administering an inhibitor of enzymatic conversion of glutamine to glutamate in an amount sufficient to inhibit the...
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5157022 |
Method for reducing blood cholesterol using arginine
A method for reducing the level of cholesterol in the bloodstream of a human being in provided. The method comprises the administration to a human or arginine derivative compound, or a related...
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5141957 |
1,4-bis-(amino-hydroxyalkylamino)-anthraquinones for inhibiting protein kinase C
The present invention provides novel substituted anthraquinones having the formula ##STR1## wherein R 1 and R 2 are independently H, alkyl, aryl, or arylalkyl; m and n are independently 1, 2,...
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5130339 |
Phenylethanolaminomethyltetralins and pharmaceutical use
New phenylethanolaminomethyltetralins of formula (I) ##STR1## wherein E represents hydrogen, (C 1 -C 4 )alkyl, (C 1 -C 4 )alkoxy, phenyl, nitro, halogen, or trifluoromethyl, L represents...
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5128325 |
Composition comprising monosodium glutamate for use in relieving fatigue
A method for relieving fatigue in a mammalian recipient by administering to the mammalian recipient an effective amount of monosodium L-glutamate or a health food composition thereof.
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5122514 |
Psoriasis treatment
The present invention relates to the use of renin inhibitors and to renin inhibitor compositions for treatment of psoriasis.
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5116872 |
Microbicidal compositions
1-Aminocyclohexanecarboxylic acid derivatives of the formula I ##STR1## or their acid addition salts or a metal complex can be employed for protecting plants from microorganisms. In the formula I,...
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5112868 |
Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition
The present invention is novel selected hydroxamic acid derivatives of acyl residues of selected NSAIDS, i.e. having 5-lipoxygenase and cyclooxygenase inhibiting properties, pharmaceutical...
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5106873 |
ACAT inhibitors
This invention relates to novel compounds which are ACAT inhibitors rendering them useful in lowering blood cholesterol levels. The compounds contain two urea or thiourea, amide, or amine moieties...
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5096926 |
Injectable formulations containing the sodium salt of naproxen
Aqueous stable injectable formulations containing the sodium salt of naproxen, stabilizing agents and polyhydroxylic alcohols, packaged in containers made up of boxes of polystyrene or of an...
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5096700 |
Halogenated aminohexanoates and aminobutyrates antimicrobial agents
The subject invention involves halogenated amino acid derivatives useful as antimicrobial agents having the structure: ##STR1## wherein --R is hydrogen or 2-aminoethyl; --R' is hydroxy, alkoxy,...
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5096712 |
Method for enhancing performance so as to improve vigor and decrease fatigue, confusion, tension, and anxiety
A composition for enhancing performance, e.g., improving subjective vigor, decreasing fatigue, diminishing subjective confusion, and decreasing tension and anxiety. The composition comprises an...
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5095037 |
Combined anti-inflammatory agent
A pharmaceutical composition for treating inflammatory diseases, comprising (A) an effective amount of hyaluronic acid or its salt, and (B) an effective amount of an anti-inflammatory agent. The...
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5087639 |
Preventing CNS toxicity of acivicin when used with four large neutral amino acids
A method for the prevention of central nervous system toxicity of acivicin which comprises the concomitant administration of acivicin and an amino acid solution consisting essentially of large...
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5079262 |
Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
A method of detecting and treating malignant and non-malignant tissue abnormalities and lesions of the skin, conjunctives, respiratory, digestive and vaginal mucosa; endometrium and urothelium in...
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5071874 |
L-carnitine magnesium citrate
L-carnitine magnesium citrate and a process for its production, starting from a magnesium compound, citric acid and L-carnitine, as well as the use of the product as a combination preparation in...
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5070080 |
Method of inhibiting generation, maturation, motility and viability of sperm with minerals in bioavailable form
A cell permeable physiologically acceptable water soluble mineral salt of a carboxylic acid such as zinc acetate, calcium acetate, zinc gluconate and the like having a pH in the range of 6.0 to 7.5...
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5068247 |
2-aminopentanoic acid compounds and their use as immunosuppressants
There are disclosed 2-aminopentanoic acid compounds represented by the formula ##STR1## wherein R is as defined in the specification, their optical isomers, their pharmacologically acceptable salts...
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5064810 |
Use of branched chain amino acids to effect diaphragm contractility and fatigue
A method for reducing respiratory muscle fatigue comprising the steps of administering a composition that includes branched chain amino acids. The composition can be administered either enterally...
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5053387 |
Omega-3 fatty acids in traumatic injury treatment
A composition and method of treating a traumatic injury by improving immunologic response and reducing a hypermetabolic response associated with those suffering from a traumatic injury such as a...
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5051249 |
Method of nutritional therapy
A method for treating a nutritional disorder in a subject. The subject's nutritional status first is assessed by measuring a selected intracellular metabolic process. Upon determination that the...
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5047425 |
Amine derivatives having cardiovascular activity
Compounds of the formula ##STR1## wherein Ar, R, R 1 , R 2 , R 3 , R 4 , X and n have the meanings mentioned in the description, processes and intermediates for their preparation, pharmaceutical...
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5036052 |
Amino acid nutrient compositions
There are herein disclosed stablized and/or dense L-amino acid nutrient compositions, i.e., amino acid infusion solutions, which contain at least one oligopeptide having at least one residue of...
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5034225 |
Stabilized human tissue plasminogen activator compositions
Disclosed are novel, stable pharmaceutically acceptable compositions containing human tissue plasminogen activator, featuring, for example, an argininium ion containing buffer as a component. Also...
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5032614 |
Serotonin antagonist
A method of suppressing vasoconstriction in a warm-blooded animal which comprises administering to said warm-blooded animal an effective amount of a serotonin antagonist compound of the formula...
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5028622 |
Administration of amino acids as treatment for neurodegenerative disorders
A treatment and composition for preventing in mammals the progressive exacerbation of symptoms associated with neurodegenerative disorders characterized by abnormal glutamate metabolism, elevated...
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5026728 |
Treatment of arthritis and inflammation using N,N-dimethylglycine
This invention relates to a method for treating arthritis and other systemic inflammatory conditions by treating the patient systemically with N,N-dimethylglycine.
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5026721 |
Amino acid nutritional supplement and regimen for enhancing physical performance through sound nutrition
An amino acid nutritional supplement and administration regimen for enhancing physical performance through sound nutrition is provided. The amino acid supplement comprises a mixture of biologically...
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