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RE36080 |
Method for augmenting fetal hemoglobin
A method is provided for inhibiting the γ to β-globin switching in subjects afflicted with β-globin disorders. The method is particularly adapted for ameliorating the clinical symptoms of sickle ce...
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5866537 |
Pharmaceutical and/or dietetic compositions with antioxidant activity containing carnosine or derivatives and branched amino acids
A pharmaceutical or dietetic composition or both a pharmaceutical and dietetic composition having antioxidant activity contains carnosine or derivatives of carnosine and leucine, isoleucine and...
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5863563 |
Treatment of pulmonary conditions associated with insufficient secretion of surfactant
Methods and compositions for the treatment of the symptoms of a patient who has a pulmonary condition associated with an inhibition of surfactant secretion by type II alveolar cells are described....
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5861431 |
Incontinence treatment
The present invention provides a method of treating incontinence in a patient that has a bladder and a urethra. The urethra forms a lumen for draining the bladder. The method comprises the steps of...
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5861434 |
Compositions containing L-carnitine or an acyl L-carnitine in combination with an ace-inhibitor for the treatment of cardiovascular disorders and a method for treating cardiovascular disorders
Compositions containing (a) L-carnitine, an acyl L-carnitine, or a pharmacologically acceptable salt thereof in combination with (b) an ACE-inhibitor are useful for treating cardiovascular...
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5861435 |
Method for preventing settlement of aquatic fouling organisms
A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to...
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5851537 |
Topical application of α-DFMO for preventing skin cancer
A salve includes a water-miscible, hydrophilic cream vehicle, 1-22% by weight a-DFMO, and no absorption enhancer. The salve is preferably contained in an ointment tube permanently sealed at one end...
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5852009 |
Compositions, including pharmaceutical compositions, for inhibiting the advanced glycosylation of proteins, and therapeutic methods based thereon
The present invention relates to compositions and methods for inhibiting protein aging. Accordingly, a composition is disclosed which comprises an agent or compound capable of inhibiting the...
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5847002 |
Compositions, for inhibition, control and regression of angiogenesis, containing hyaluronic acid and NSAID
The use of:(a) a non-steroidal anti-inflammatory agent,and(b) hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and subunits of...
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5843997 |
Excitatory amino acid receptor antagonists
The present invention provides novel compounds that affect excitatory amino acid receptors and are useful in the treatment of neurological disorders. This invention also provides synthetic methods...
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5834516 |
Meadowfoam betaines in personal care applications
The present invention deals with the composition of matter and the utilization of certain novel meadowfoam based betaine compounds. These materials are useful in personal care applications.
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5834517 |
Meadowfoam sulfosuccinates in personal care applications
The present invention deals with a process for cleaning and conditioning hair and skin which comprises the contacting of hair or skin woth an effective concentration of certain novel meadowfoam...
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5830919 |
Method to protect plants from fungal infection
A method for protecting a crop against fungal diseases by inducing local and systemic resistance of the crop comprising applying to the crop or its locus a composition containing an effective...
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5827886 |
Composition for relief of arthritis-induced symptoms
A composition and method of using it for ameliorating inflammatory reactions and painful and other symptoms of the diseases of arthritis, lumbago, low back pain, myalgias and neuralgias. The...
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5827820 |
Aqueous peritoneal dialysis solution
The subject matter of this invention concerns an aqueous peritoneal dialysis solution which is obtained immediately prior to administration from two individual solutions, the first of which...
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5824708 |
Virucidal substances
The process of reducing the count of a virus by contacting the virus with (1) the reaction product of a) N-substituted propylenediamines corresponding to formula I: R1 --NH--CH2 --CH2 --CH2 --NH2...
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5817329 |
Nutritional supplement for increased muscle size and strength for body builders
The present invention relates to the method and composition for use of diet supplements by athletes and bodybuilders. A first supplement comprising, the amino acid acetyl-L-Carnitine, in...
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5817621 |
External remedy possessing trophoprotective effect
A dermatological composition for external use comprising a lipid ointment base, vitamin A, a salicylic acid or a derivative thereof, D-camphor, a biogenic GABAergic substance, a biogenic...
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5817695 |
Nutritional product with high fat, low carbohydrate and amino acid imbalance
A nutritional product is provided for cancer patients comprising, as per caloric requirement, a low concentration of carbohydrate, a high concentration of fat and an imbalance of amino acids...
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5798363 |
Use for tachykinin antagonists to treat emesis
The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel...
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5798371 |
Pharmaceutical composition endowed with an antialcoholic and nootropic effect
A pharmaceutical composition having an antialcoholic and nootropic effect which is administered sublingually. The active ingredients of the composition are the amino acid L-threonine or a...
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5792796 |
Methods for treating anxiety and panic
The instant invention is novel uses of known cyclic amino acids. Such compounds as gabapentin are useful in the treatment of anxiety and in the treatment and/or prevention of panic attacks.
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5789443 |
Method for treating flushing associated with menopause
A method for treating flushing as a symptom of menopause is disclosed. Specifically, the method comprises administering to a patient in need thereof an effective amount of leucine, or leucine in...
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5788958 |
Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders
The present invention is directed to the use of an inhibitor of NO activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as an antitumor therapy to reduce tumor blood flow and...
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5783593 |
Inhibitors of squalene synthetase and protein farnesyltransferase
The present invention provides a compound of the formula ##STR1## which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia,...
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5776503 |
Amino acid solutions for treatment of peritoneal dialysis patients
The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to...
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5770619 |
Method of activating photosensitive agents
A method of administering photodynamic therapy begins with administering to an animal an effective amount of a photosensitizing agent which is less than about one half of the usual clinical dose...
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5770622 |
Method of preserving materials using 4-methylene-2-amino-cyclopentane-1-carboxylic acids
The invention relates to cyclopentane- and -pentene-β-amino acids, processes for their preparation and their use as medicaments, and to prevent contamination of materials such as wood and leather.
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5767091 |
Analgesic effect enhancing preparations
The present invention provides an analgesic effect enhancing preparation capable of enhancement of the effect of analgesics, the preparation comprising as an active ingredient the following amino...
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5753254 |
Therapeutic agents containing thyroid hormones
There is disclosed a solid fast dispersing dosage form of a pharmaceutical composition suitable for oral administration comprising: a therapeutic agent which comprises one or more compound thyroid...
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5750558 |
Oxime derivatives of indole and indene compounds as inhibitors of prostaglandin biosynthesis
Described herein are compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein L is selected from the group consisting of ##STR2## R2 is selected from (a) ##STR3##...
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5746998 |
Targeted co-polymers for radiographic imaging
A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic...
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5741817 |
Use of low molecular weight amino acids in ophthalmic compositions
The use of glycine and other low molecular weight amino acids in ophthalmic compositions (e.g., preserved saline solutions) is described. These compounds have been found to enhance the efficacy of...
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5739163 |
Aromatic compounds containing basic and acidic termini useful as fibrinogen receptor antagonists
This invention relates to novel compounds containing basic and acidic termini, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using...
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5739160 |
Cyclopentane- and -pentene-β-amino acids
New Cyclopentane- or cyclopentene-beta-aminoacid derivatives and their isomers, acid additional salts and metal salt complexes have strong antimicrobial and broad-spectrum antimycotic acitivity. As...
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5739164 |
Pharmaceutical compounds for the treatment of CNS diseases
Disclosed herein is a method of treating a disease of the central nervous system with a compound of the formula ##STR1## in which m is 0, 1 or 2, n and q are each 0 or 1 to 5, and p is 0 or 1, X is...
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5736563 |
Transcutaneous in vivo activation of photosensitive agents in blood
A method destroys or impairs target cells that have selectively accumulated a photosensitizing agent. The target cells are in the bloodstream of an intact animal, which bloodstream and animal...
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5733539 |
Bait for fishes and shellfishes
The invention discloses a bait for fishes and shellfishes characterized in that the bait comprises a matrix material containing a microorganically fermented product of a plant residue obtained by...
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5731349 |
Medicinal preparation of antistress, stess-protective and nootropic effect
A pharmaceutical preparation of antistress, stress-protective and nootropic effect contains an effective substance represented by an amino-acid glycine or its pharmaceutically acceptable salt.A...
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5731348 |
Alkylcarboxy amino acids-modulators of the kainate receptor
Compounds of a new class of alkyl carboxy amino acid analogs of glutamic acid act as specific regulators of the kainic acid EAA receptor cation channel. These compounds are useful for treating...
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5731290 |
Method of improving the immune response
The invention provides diet supplements for pre-operative treatment of patients due for surgery.
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5728675 |
Antemortem nutrient supplement for livestock
The invention relates to an antemortem stress supplement for livestock containing one or more sources of electrolytes including sodium, potassium and magnesium, one or more sources of amino acids...
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5728736 |
Reduction of hair growth
Mammalian hair growth is reduced by applying to the skin a dermatologically acceptable composition including an inhibitor of arginase.
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5728678 |
Method and composition for providing nutrition to a renal failure patient
The present invention provides a composition as well as method for providing nutrition to renal patients. Pursuant to the present invention, the enteral composition includes an effective amount of...
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5728683 |
External escinol preparation for skin
An external preparation for skin comprising at least one member selected from the group consisting of escinol and its salts represented by the following constitutional formula (1): ##STR1##...
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5723448 |
Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction
Administration of argininosuccinate synthetase activity reducing agents, e.g., argininosuccinate synthetase induction blocking agents (e.g., antibiotics that bind to DNA sequences present in the...
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5721278 |
Ovulation control by regulating nitric oxide levels
Inhibition of ovulation in a female may be achieved by administering a nitric oxide synthase inhibitor, alone or in combination with one or more of a progestin, an estrogen, and an LH-RH...
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5719119 |
Parenteral nutrition therapy with amino acids
Parenteral nutrition aqueous solutions are provided which preferably contain glutamine together with other organic nitrogen containing compounds. The respective concentrations of the compounds...
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5719133 |
Adolescent dietary composition
A dietary composition comprising, based on total caloric content of the composition, a) a carbohydrate component which comprises from 50 to 65% of the total caloric content; b) a lipid component...
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5719134 |
Method of providing nutrition to adolescents
A dietary composition comprising, based on total caloric content of the composition, a) a carbohydrate component which comprises from 50 to 65% of the total caloric content; b) a lipid component...
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