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7619003 |
Process for producing optically active compound
A process for producing an optically active compound based on the hydrolysis of an alkenyl ester compound or the cleavage of an alkenyl ether compound. The process uses neither an acidic compound...
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7612111 |
Esterified fatty acid composition
The invention is directed to compositions comprising lecithin, olive oil, esterified fatty acids and mixed tocophenols for use in the treatment and prevention of various types of arthritis and...
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7608642 |
Wound and skin care compositions
The invention provides compositions and methods that employ compounds that can promote skin cell renewal, wound healing, proliferation of fibroblasts and/or keratinocytes, and production of...
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7608639 |
Phenoxyether derivatives as PPAR modulators
The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders...
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7605182 |
Compounds that selectively bind to membranes of apoptotic cells
The invention relates to compounds that selectively bind to phospholipid membranes having the features of membranes of apoptotic cells, pharmaceutical compositions comprising the same and...
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7605124 |
Ejection liquid and ejection method
An ejection liquid that allows a solution containing at least one kind of insulins to be stably ejected by an inkjet system using a thermal energy and a method of ejecting the solution containing...
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7592015 |
Use of high oleic high stearic oils
The invention relates to the use in food products, such as spreads, sauces, ice-cream, soups, bakery products, and confectionery products, and cosmetic products, such as creams, lotions, lipsticks,...
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7585460 |
Method for inhibiting the biological acidification of water in contact with materials containing sulfur
The invention relates to a method for inhibiting the biological acidification of water which is in contact with materials containing sulfur in reduced form or with elemental sulfur, susceptible to...
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7582803 |
Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I:
where the definitions of the variables Q,...
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7582424 |
Accessory cholera enterotoxin and analogs thereof as activators of calcium dependent chloride channel
Vibrio cholerae accessory cholera enterotoxin (ACE) activates a calcium dependent chloride channel. Ace and Ace analogs can be administered to patients to treat diseases involving defects in...
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7579370 |
Fused heterocycles
This invention provides fused heterocycles having the formula:
in which R 1 is a member selected from the group consisting of H, substituted or unsubstituted arylalkyl and substituted or...
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7579020 |
Controlled release arginine α-ketoglutarate
An oral formulation of arginine α-ketoglutarate is disclosed which formulation is comprised of arginine α-ketoglutarate and one or more excipient materials. A wide range of different controlled...
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7572460 |
Hydrogen cyanamide pesticide formulations
Agricultural crops are protected from the growth of undesirable vegetation as well as nematode and insect infestations, by the application of hydrogen cyanamide in combination with a short-chain,...
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7569232 |
Medium chain peroxycarboxylic acid compositions
The present invention relates to compositions including medium chain peroxycarboxylic acid, methods for making these compositions, and methods for reducing the population of a microorganism. The...
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7547729 |
1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same
The invention relates to substituted 1,3-diphenylprop-2-en-1-one derivative compounds, pharmaceutical and/or cosmetic compositions containing same, and the applications thereof in therapeutics and...
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7547673 |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising...
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7528173 |
Plasma carboxypeptidase B inhibitors
Compounds of the following formula (I), for example: (1), wherein R 1 , R 2 , R 3 , and R 4 are described herein, are useful as inhibitors of plasma carboxypeptidase B. Pharmaceutical compositions...
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7517909 |
Amino acids with affinity for the α2δ-protein
This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the...
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7514471 |
Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor α (PPAR)
The present invention provides the S enantiomer of a compound of formula (I) wherein n is 1 or 2 as well as pharmaceutically acceptable salts, solvates, crystalline forms and prodrugs thereof, to...
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7504435 |
Method for stimulating weight loss and/or for lowering triglycerides in patients
Administration of a therapeutically effective amount of 3,5-diiodothyropropionic acid stimulates weight loss in patients, lowers triglyceride levels and reduces risk of death or progression of...
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7504428 |
2-phenyl-3,3,3-trifluoro-2-hydroxy-propionic acid derivatives
The present invention a method of treating anxiety by administering compounds that are active on the GABA B receptor, having formula I:
wherein R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are as...
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7504231 |
Method of alleviating chronic pain via peripheral inhibition of neurotransmitter synthesis
A composition having sustained pain-relieving properties such that the composition may be administered to a subject to alleviate chronic pain. The composition includes an effective amount of at...
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7495030 |
(5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents
(5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid, salts thereof, and compositions containing the same for the delivery of active agents are provided. Methods of administration, treatment of disease...
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7491747 |
Butyric acid derivatives
The present invention relates to a compound of the formula I: (Formula I) in which: A, B, R 1 , Z, n and R 2 are as defined in claim 1 . These compounds are useful in the treatment of...
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7485326 |
Oral microemulsion composition comprising biphenyldimethyldicarboxylate and silybin
A microemulsion composition comprising biphenyldimethyldicarboxylate (BDD) and silybin or a derivative thereof, or a <i> Carduus marianus </i> extract containing silybin and derivatives...
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7485315 |
Compositions comprising a compound of low solubility and a lipophilic amino acid derivative, uses thereof and process for dissolving a compound of low solubility
The invention relates to a process for dissolving at least one compound of low solubility in water, the said process comprising the essential step of mixing the compound of low solubility with at...
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7482377 |
Pharmaceutical compositions and methods of treatment based on diclofenac
New pharmaceutical compositions for oral use containing diclofenac together with alkali metal bicarbonates in amounts of from 20 to 80 by weight with respect to diclofenac are described. These...
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7476692 |
Pharmaceutical compositions of safingol and methods of using the same
The present invention provides stable aqueous solutions consisting essentially of: (a) a sphingolipid; (b) lactic acid; and (c) optionally a stabilizing agent; wherein the solution has a molar...
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7476660 |
Composition and method for organ preservation
The present invention relates to a composition for organ preservation, comprising an inulin type fructan as an active ingredient. The composition for organ preservation can suppress the...
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7473705 |
Hexafluoroisopropanol substituted ether derivatives
The invention is concerned with novel hexafluoroisopropanol substituted ether derivatives of formula (I):
wherein R 1 to R 3 are as defined in the description and in the claims, as well as...
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7470657 |
Cleansing composition containing an amphiphilic polymer
The present patent application relates to a cleansing composition comprising in an aqueous medium at least one surfactant selected from alkylpolyglycosides, maltose esters, glycerolated fatty...
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7470313 |
Amino acid-solubilized borate, silicate and zinc compositions and methods for treating wood products
Compositions and methods are provided for treating products containing wood fibers to provide protection against wood destroying organisms and fire, and resistance against leaching of the...
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7462227 |
Ibuprofen complexes as wood preservatives
Complexes of ibuprofen and copper and/or zinc were solubilized in ammoniacal solution providing preservative solutions that fully penetrate wood. With loss of the ammonia from the wood, the...
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7452556 |
Compositions for the treatment of pilosebaceous gland inflammations comprising aluminum fluoride
The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and...
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7452545 |
Oligosaccharide aldonic acids and their topical use
Compositions comprising oligosaccharide aldonic acids are useful for general care, as well as for treatment and prevention, of various cosmetic conditions and dermatological disorders, including...
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7432247 |
Methods of cardioprotection using dichloroacetate in combination with an inotrope
The present invention provides compositions and methods for maintaining cardiac function by administering dichloroacetate (DCA) in combination with an inotrope.
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7427619 |
Formulation of amino acids and riboflavin useful to reduce toxic effects of cytotoxic chemotherapy
Pharmaceutical compositions effective in alleviating or reducing the effects of fatigue and weakness associated with cancer and cancer chemotherapy are disclosed. The pharmaceutical compositions of...
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7423063 |
Calcium salts with cytotoxic activity
Calcium salts, in particular calcium trifluoroacetate, are added to medicaments to provide cytotoxic and antitumoral activity. The medicaments can be administered to cancer patients as part of a...
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7410655 |
Anticancer agent
An anticancer agent containing platinum preparation, humic substances, water and sodium chloride. Potassium tetrachloroplatinate is used as a platinum compound and lignohumic acid ammonium salts...
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7404949 |
Methods and compositions useful to prevent in-grown hair arising from shaving
A method and composition is provided for managing in-grown hair which involves applying to those areas malonic acid or a salt thereof in a carrier. The method and composition allows for comfortable...
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7399790 |
Virucidal compositions
A method of inactivating enveloped virus comprises contacting said virus with a virucidally effective amount of a composition comprising a C1 to C3 monohydroxy alcohol or a C3 to C4 diol and a...
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7399786 |
Derivatives of amino acids for treatment of obesity and related disorders
Novel amino acid derivatives are provided that are useful for management of disorders such as obesity and immunological diseases. The derivatives are also useful in lowering blood glucose levels in...
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7399785 |
N-oxides and derivatives of melphalan for treating diseased states associated with hypoxia inducible factor
This invention relates to compounds which are N-oxides and derivatives thereof, as well as their use to treat HIF related diseases. These compounds have the general formula set out below and are...
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7396946 |
Compound for treatment of external secretion disorders
Disclosed is a method for treatment of external secretion disorders, which comprises administering a fatty 5 acid derivative to a subject in need of said treatment. The method of the present...
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7393812 |
Methylidene mevalonates and their use as herbicides
Methylidene mevalonic acid, a material isolated from a fungal extract, and its primary alcohol and carboxylic acid derivatives, are potent herbicides demonstrating a broad spectrum of weed control....
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7390504 |
HDL-boosting combination therapy complexes
A pharmaceutical composition including therapeutically effective amounts of at least one HMG-CoA reductase inhibitor present as a dyhydroxyacid salt and at least one additional therapeutic agent.
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7381416 |
Selenohydroxy acids and their derivatives, applications in nutrition, cosmetics and pharmaceutics
The purpose of this invention is:
new selenohydroxy acid compounds and their derivatives; their process for the preparation; use of the new compounds as precursors of L(+)-selenomethionine...
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RE40360 |
Methods for inhibition of angiogenesis with a composition comprising 3-hydroxythalidomide
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, thalidomide and various related compounds such as thalidomide precursors, analogs,...
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7364751 |
Stabilized compositions of aqueous reduced coenzyme Q solution
The present invention provides a reduced coenzyme Q-containing solution capable of being retained more stably against oxidation, by using a reduced coenzyme Q which is hydrophobic and susceptible...
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7358278 |
Cellular phosphorylation potential enhancing compositions preparation and use thereof
A pharmaceutical composition comprising as an active phosphorylation potential enhancing substance a pharmaceutically-acceptable salt of an alpha-keto carboxylic acid thereof alone or in...
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