Patents in Class 514/555

Matches 1 - 50 out of 119

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Match	Document	Document Title
1	7592478	Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof Novel ligand antagonists of the RAR receptors have the following structural formula (I): in which A is a CH 2 , CHOH, C═O or C═N—OH radical or a sulfur or selenium atom; B is a radical...
2	7390833	Method for treating ADAMTS-5-associated disease The present invention relates to methods of treating ADAMTS-5-associated diseases and particularly osteoarthritis comprising administering an agent capable of modulating ADMATS-5 activity to a...
3	7309755	Method of producing polycarbonate articles by rotation molding and rotation molded articles made by the method A method for making a polycarbonate article is described wherein the article is made by rotation molding a melt polycarbonate having a weight average molecular weight from 25,000 to about 36,000....
4	7135497	Treating neural conditions resulting from spinal cord contusions and other causes β 2 -agonists, such as clenbuterol and salbutamol can enhance the recovery of locomotive function and/or neuromuscular strength following spinal cord injuries or as a result of degenerative neural...
5	7067555	Sertraline oral concentrate The present invention provides an essentially nonaqueous, liquid pharmaceutical concentrate composition for oral administration containing sertraline or a pharmaceutically acceptable salt thereof...
6	7014864	Formulations comprising lipid-regulating agents The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one structured lipid as the primary solvent medium for said agent. One or more...
7	7005449	Tolterodine salts The present invention concerns novel pharmaceutically active compounds, pharmaceutical compositions containing the same, the compounds for use as medicaments, and use of the compounds for the...
8	6984389	Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a...
9	6982097	Biocidal compositions and methods of using same This invention relates to biocidal compositions and methods of using same. Also provided is a process for the manufacturing of a biocidal composition in the form of a tablet and a method of using...
10	6838091	Formulations comprising lipid-regulating agents The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers...
11	6750229	Methods for treating skin pigmentation This invention relates to methods and compositions for bringing about changes in skin pigmentation. More particularly, this invention relates to compounds which affect melanogenesis and can be used...
12	6730702	Therapeutic agents for inflammatory diseases of intestine The present invention provides a novel agent for prophylaxis or treatment of inflammatory bowel diseases for oral administration or intra-intestinal infusion, which comprises as an active...
13	6730667	Iontophoresis disc pain blocker Treatment of pain syndromes utilizes a topical polypharmaceutical preparation of phenoxybenzamine, ketamine, gabapentin, nifedipine, carbamazepine, or combinations of them. Other suitable...
14	6576664	Inhibitors of aggrecanase and matrix metalloproteinases for the treatment of arthritis This invention relates to molecules which inhibit metalloproteinases, including aggrecanase, and the production of tumor necrosis factor (TNF). In particular, the compounds are inhibitors of...
15	6468554	Sensorially active substance embedded in plastic Denatonium benzoate (Bitrex™) dissolves in molten flexible polyvinyl chloride, imparting a bitter flavor to the plastic which discourages rats from gnawing on it. Denatonium benzoate can in all...
16	6372790	Pharmaceutical composition comprising a combination of metformin and fibrate, and its use for the preparation of medicines intended to reduce hyperglycaemia A pharmaceutical composition comprising: (i) metformin, optionally in the form one of its pharmaceutically acceptable salts; (ii) a fibrate selected from fenofibrate and bezafibrate; and optionally...
17	6372789	Bacteriocide compositions for agricultural and horticultural use The novel agricultural and horticultural fungicidal compositions containing as active ingredients a combination of A) 1,1′-iminiodi(octamethylene)diguanidine of the formula (iminoctadine) or...
18	6344479	Method of preventing retinopathy of prematurity in a neonate A method is disclosed of preventing retinopathy of prematurity in a prematurely born neonate susceptible to developing retinopathy of prematurity, which comprises the step of parenterally...
19	6337080	Insect control mat An insect control mat having a heatable substrate; an insect control active material; and an aversion material in an amount effective to cause a person to avoid retaining the mat in the person's...
20	6248782	Method of treating viral diseases A therapeutic process for treating disease in mammals caused by retroviruses in which the infected mammal is treated with a ribonucleotide reductase inhibitor such as a polyhydroxy benzoic,...
21	6221907	Tricyclic compounds having activity specific for integrins, particularly alphanubeta3 integrins, method for preparing same, intermediates therefor, use of said compounds as drugs, and pharmaceutical compositions containing same
22	RE36854	Vitamin D compounds and method of preparing these compounds The invention relates to a new vitamin D compound of the general formula ##STR1## wherein: R 1 is a hydrogen atom or a hydroxy group; R 2 is a (C 1 -C 3 )alkyl group, a hydroxy(C 1 -C 3...
23	5998395	Methods of treating inflammatory dermatosis Inflammatory dermatoses are controlled and cleared by topical application to the affected areas of the skin of a composition containing both a corticosteroid and a retinoid. The combined therapy is...
24	RE36419	Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx The present invention provides novel methods for prevention or treatment of primary and recurring squamous cell carcinoma of the oral cavity or oropharynx comprising topical administration, to the...
25	5891856	Method for protection against genotoxic mutagenesis A method and pharmaceutical for protecting against mutational damage in mammalian cells, irrespective of the nature of the mutagenic event or source of radiational or chemical insult or the like.
26	5863941	Method and composition of a topical treatment of inner ear and labyrinth symptoms Periauricularly administered topical therapy with a carrier system containing local anesthetics is a new and effective treatment of disorders of the inner ear and labyrinth, which has a low...
27	5811459	Ortho substituted aromatic compounds useful as antagonists of the pain enhancing effects of E-type prostaglandins The invention relates to compounds of the formula (I): ##STR1## wherein A, B and D are various ring systems such as phenyl, R 1 includes carboxy, R 3 is hydrogen or C 1 -4 alkyl and Z is a...
28	5728734	Pesticide preparation of aqueous suspension type A pesticide preparation of aqueous suspension type which comprises: (a) a 1,1'-iminiodi(octamethylene)diguanidinium tris(alkyl-benzenesulfonate) as an active pesticide ingredient; (b) at...
29	5700833	Isocarbacyclin derivatives The present invention provides novel isocarbacyclin derivatives useful for search and study of prostacyclin receptor and as a therapeutic drug for central nervous system diseases, which derivatives...
30	5691376	Substituted biphenyl derivatives A compound of the following structure: ##STR1## wherein R 8 =H: R 1 =alkyl, cycloalkyl, arylalkyl, aryl; R 2 =cycloalkyl, aryl, C 3 -C 10 alkyl; X,Y=O, S(O) n , NH; Z=CO 2 R 3 ,...
31	5681838	Substituted amino compounds, their preparation and their use as inhibitors of thrombocyte-aggregation The present invention relates to novel substituted amino compounds of the formula I: R 1 -(A) a -(B) b -(D) c -(CH 2 ) m -N(R 2 )-(CH 2 ) n -R 3 as defined in the present application, and...
32	5637616	Method for treating diseases mediated by proteases A method for the topical or systemic treatment of disorders mediated by proteases which result in skin or mucosal lesions, and in particular, pemphigus, cicatricial pemphigoid, bullous pemphigoid,...
33	5614554	Reverse transcriptase inhibitors and antiviral agents The present invention provides a reverse transcriptase inhibitor and an antiviral agent comprising at least one member selected from the group consisting of sulfated tyrosines and physiologically...
34	5510385	Pharmaceutical compositions containing the salts of S(+)-2-(4-isobutylphenyl)propionic acid with basic aminoacids A pharmaceutical composition for oral use containing the salt of S(+)-2-(4-isobutylphenyl)propionic acid with a basic aminoacid selected between L-arginine and L-lysine is described.
35	5496857	Whitefly insecticide A specially formulated environmental insecticide is provided which effectively controls whiteflies and other insects but is safe to humans, farm animals, pets, crops, and fish. The cost-effective...
36	5385931	Sulfonamides derived from benzocyclic or benzoheterocyclic acids, their preparation and application in therapeutics The invention relates to new sulphonamide derivatives of benzo-cyclic or benzo-heterocyclic acids and their derivatives of general formula I ##STR1## in which: R represents a straight-chain or...
37	5331011	N-benzyl-n-phenoxyethylamines and agricultural and horticultural bactericides Disclosed is an N-benzyl-N-phenoxyethylamine selected from the group consisting of the N-benzyl-N-phenoxyethylamine represented by the following formula (I): ##STR1## and an agriculturally...
38	5132118	Treatment of exercise-induced pulmonary hemorrhage in animals A method and composition for the preventive and curative treatment of exercise-induced pulmonary hemorrhage in animals. The method comprises administration to the animal of a mixture of urea,...
39	5114716	Anti-oxidant system containing stabilized ascorbyl ester, tocopherol or cafeic acid or a derivative thereof, a complexing agent and a polypeptide, and compositions containing the anti-oxidant system An anti-oxidant system contains, in combination, at least one stabilized ascorbyl ester, at least one tocopherol or a mixture of tocopherols, or cafeic acid or a derivative thereof, at least one...
40	5084214	Phenolic thioethers, and their production and use Phenolic thioethers of the formula: ##STR1## wherein R is a hydrogen atom or a protective group for carboxyl, X is a straight or branched C 4 -C 15 alkylene group, a straight or branched C 1 -C...
41	5011854	Hydroxamic acid derivatives and use thereof in combatting lipoxygenase-mediated diseases A hydroxamic acid compound represented by the general formula (I) or a salt thereof; ##STR1## wherein R 1 represents a hydrogen atom, or a substituted or unsubstituted alkanoyl group, R 2 ...
42	4960772	Benzoyl peroxide and quaternary ammonium based pharmaceutical and cosmetic compositions A pharmaceutical and cosmetic composition for topical application comprises in a physiologically acceptable medium a combination of benzoyl peroxide and a quaternary ammonium salt selected from a...
43	4959394	Novel Guanidinium aspartates The L-arginine salt of N-(D)-{[2-(2,6-dichlorophenylamino}phenyl]acetyl]aspartic acid, represented by the formula ##STR1## in which AmH ♁ represents the cation derived from L-arginine Am of the...
44	4945112	Guanidinium compounds and fungicides containing them Guanidiniumdodecylbenzene sulfonates of the formula ##STR1## where R is the group --H, --CH 3 or ##STR2## and X is 1, 2, 3 or 4, and fungicides containing these compounds.
45	4897422	Lipoxygenase inhibiting compounds Compounds of the formula: ##STR1## where R 1 is amino or methyl; R 2 is C 1 -C 2 alkyl; R 3 is one or more substituents selected from hydrogen, halogen or trihalomethyl; R 4 is one or more...
46	4895842	Phenylalanine derivative and proteinase inhibitor A phenylalanine derivative having the formula (I): ##STR1## where R 1 and R 2 are independently hydrogen provided that both R 1 and R 2 are not hydrogen at the same time; C 1 -C 8 alkyl...
47	4891386	Lidocaine derivative and therapeutic compositions which contain it as principal active ingredient A new compound, namely lidocaine salicylate monohydrate of formula: ##STR1## has been proposed, which has shown strong local anesthetic and cardiac antiarrhythmic activity.
48	4883786	Derivatives of L-carnitine Novel derivatives of L-carnitine or of L-acylcarnitines or of esters thereof, obtained by salification with suitable acids or acidic aminoacids, monosalified with potassium ion. These derivatives...
49	4880840	Arylethanolhydroxylamines and their use for promoting yield
50	4876282	1-Phenylalkylamines as selective serotonin uptake inhibitors The present invention provides 1-phenyl-(naphthalenyl)alkylamines which are selective inhibitors of serotonin uptake.

Matches 1 - 50 out of 119

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