|
Match
|
Document |
Document Title |
|
|
7589220 |
Inhibitors of the anandamide transporter
Disclosed are compounds that are anandamide transport inhibitors and their pharmacological use.
|
|
|
7528169 |
Substance having antitumor/anti-inflammatory activity
A compound represented by the following formula (I) or a salt thereof which has excellent antitumor activity and angiogenesis inhibitory action in a low oxygen condition, and a medicament such as...
|
|
|
7465820 |
Abiotic heparin antagonists
The present invention relates to heparin-binding calixarene compounds of general Formula (I) in which R, R 1 , L and n have the meanings indicated in the description and their use in the biomedical...
|
|
|
7462646 |
Osteoclastogenesis inhibitors and uses thereof
The present invention provides a method of reducing or inhibiting osteoclast development induced by the receptor for activation of nuclear factor kappa B ligand (RANKL), comprising the step of...
|
|
|
7427414 |
Modified release oral dosage form using co-polymer of polyvinyl acetate
Once a day modified release oral dosage form comprising of granules or pellets which are either compressed into tablet or filled inside the capsule, wherein the pellet has a core of active...
|
|
|
7407778 |
Compounds, compositions and methods for treating neuropsychiatric disorders
Acetyl- L -carnitine (ALCAR) and L-carntine (LCAR) are nutraceuticals with indications in treating a variety of mental health disorders. A metabolomics-guided bioprocess method is presented to...
|
|
|
RE40246 |
Method for the suppression of viral growth
A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula:
wherein R 1 , R 2 , R 3 and R 4 are...
|
|
|
7351424 |
Enhanced purity trans-lutein-ester compositions and methods of making same
The present invention relates a composition having a high content of xanthophyll esters, where the xanthophyll ester component of the composition is comprised of a high proportion of trans-lutein...
|
|
|
7342046 |
Gossypol co-crystals and the use thereof
This invention relates to compositions comprising co-crystals of (−)-gossypol with a C 1-8 carboxylic acid or C 1-8 sulfonic acid which are useful as inhibitors of Bcl-2 family proteins. The...
|
|
|
7320998 |
Carbohydrate analog inhibitors of alpha-amylase
The present invention provides carbohydrate analogs of the formula:
wherein X is CH 2 , O, or NH, and R 1-8 are independently H, a short hydrocarbon, a substituted amine, an alcohol, a...
|
|
|
7282521 |
Anti-retroviral moronic acid derivatives
The present invention provides moronic acid derivatives of the general formula:
which have antiviral activity, along with compositions containing the same and methods of use thereof.
|
|
|
7262218 |
Forms of pravastatin sodium
New polymorphic forms of pravastatin sodium are provided. Each of the new forms is selectively obtained by crystallization from different solvent systems, each solvent system having a protic...
|
|
|
7129231 |
Regulation of intracellular glucocorticoid concentrations
This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be...
|
|
|
7122532 |
Regulation of intracellular glucocorticoid concentrations
This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be...
|
|
|
7122531 |
Regulation of intracellular glucocorticoid concentrations
This invention relates to the interconversion of inactive 11-keto steroids with their active 11B-hydroxy equivalents, to methods by which the conversion of the inactive to the active form may be...
|
|
|
7056935 |
Rotamase enzyme activity inhibitors
This invention relates to methods of using neurotrophic compounds having an affinity for FKBP-type immunophilins to stimulate or promote neuronal growth or regeneration and to prevent neuronal...
|
|
|
7034015 |
Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
|
|
|
RE39072 |
2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same
The present invention relates to a compound of the general formula
wherein R 1 , R 2 , R 3 and R 4 are each a hydrogen or an acyl, a pharmaceutically acceptable acid addition salt thereof or...
|
|
|
7026355 |
Use of rhein or diacerhein compounds for the treatment or prevention of vascular diseases
The present invention relates to the use of rhein or diacerhein compounds to treat and prevent vascular diseases that cause obstruction of the vascular system such as blood vessel restenosis and...
|
|
|
6998422 |
Lipid peroxide-lowering compositions
Compositions having excellent blood lipid peroxide lowering activity are provided. In particular, compositions for lowering lipid peroxides in the blood which contain pravastatin together with at...
|
|
|
6994866 |
Combinations of active ingredients, which exhibit insecticidal and acaricidal properties
The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing
(a) cyclic ketoenols having the formula
in which the...
|
|
|
6992106 |
Anti-tumor composition
The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors,...
|
|
|
6974834 |
Process for preparing enantiomerically enriched (1S,4R) 1-acetoxy-4-hydroxycyclopent-2-ene
This invention relates to a process for the synthesis of enantiomerically enriched (1S,4R) 1-acetoxy-4-hydroxycyclopent-2-ene of Formula I, a compound useful as an intermediate in the synthesis of...
|
|
|
6967218 |
Pravastatin pharmaceutical formulations and methods of their use
The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutically acceptable salt thereof, and methods of their use. The present...
|
|
|
6916849 |
Compositions for improving lipid content in the blood
The present invention relates to compositions for lowering the total amount of cholesterol in the blood and methods of using the compositions. The compositions are a mixture of pravastatin and one...
|
|
|
6911472 |
Pharmaceutical composition comprising a hmg-coa reductase inhibitor
A pharmaceutical composition comprising as an active ingredient an HMG-CoA reductase inhibitor and an aminosugar.
|
|
|
6903076 |
Antihelminthic anthraquinones and method of use thereof
Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the...
|
|
|
6903052 |
Nematicidal compositions and methods
The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes that parasitize animals can also be controlled...
|
|
|
6890941 |
Compositions containing HMG Co-A reductase inhibitors and policosanol
The present invention provides pharmaceutical compositions, methods, combinations, and kits for treating a disorder related to elevated serum cholesterol concentration, for example,...
|
|
|
6875746 |
Anticancer anthraquinones and method of use thereof
Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the...
|
|
|
6872748 |
Simplified resiniferatoxin analogues as vanilloid receptor agonist showing excellent analgesic activity and the pharmaceutical compositions containing the same
The present invention is related to new vanilloid analogues containing resiniferatoxin pharmacophores, pharmaceutical compositions that have such analogues, and their uses as vanilloid receptor...
|
|
|
6858650 |
Stable salts of novel derivatives of 3,3-diphenylpropylamines
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
|
|
|
6858649 |
Selective potentiation of serotonin receptor subtypes
The selective potentiation and/or inhibition of the 5-HT 2A and/or 5-HT 1A response to serotonin (5-HT) is achieved using analogs of oleamide. Selective potentiation and/or inhibition of the 5-HT...
|
|
|
6844320 |
Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both,...
|
|
|
6730329 |
Zinc containing compositions for anti-viral use
One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one...
|
|
|
6696490 |
Slow release insect repellent compounds and process for delivering active
Novel insect repellents having ester bonds such that when deposited on skin, natural skin cleaning agents provide slow release of the active.
|
|
|
6620590 |
Diagnosis of pre-eclampsia
A method for diagnosis of pre-eclampsia is disclosed, which comprises measuring the hormone inhibin A in a biological sample such as maternal serum. The method allows non-invasive, early diagnosis...
|
|
|
6610744 |
Methods of treatment with compounds having RARα receptor specific or selective activity
Retinoid compounds which act specifically or selectively on RAR α receptor subtypes in preference over RAR β and RAR Γ receptor subtypes, posses desirable pharmaceutical properties associated...
|
|
|
6608107 |
Methods and compositions to treat conditions associated with neovascularization
This invention also provides a method to inhibit neovascularization in tissue by delivering to the cell or tissue an effective amount of gossypol, or a pharmaceutically acceptable salt, derivative...
|
|
|
6562782 |
Oligocycloalkanoid compounds and methods of use
The present invention related to an oligocycloalkanoid compound comprising formula (I) wherein m, n, and o are independently an integer from 0 to 2; A 1 through A 10 are independently a direct...
|
|
|
6534542 |
(2-hydroxy)ethyl-thioureas useful as modulators of α2B adrenergic receptors
Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α 2B and/or α 2C adrenergic receptors...
|
|
|
6492418 |
Compositions containing a benzamide disulfide derivative for treating allergic diseases
Methods and compositions for preventing or treating allergic diseases of the eye, nose, skin, ear, gastrointestinal tract, airways or lung and preventing or treating manifestations of systemic...
|
|
|
6465516 |
Method of stimulating nitric oxide synthase
A method for treating a subject who would benefit from increased nitric oxide production comprising administering inhibitors of Hmg-CoA-Reductase is disclosed for the treatment of diseases related...
|
|
|
6391916 |
Enediyne derivatives
Novel C 3 -substituted cyclodeca-1,5-diynes can be prepared through novel synthetic procedures using starting (E)-C 3 -substituted-4-(aryl- or heteroarylmethylidene)cyclodeca-1,5-diynes reagents....
|
|
|
6355673 |
Substituted diaminocarboxylic acids
Compounds of formula (I) are suitable for the production of pharmaceuticals for the prophylaxis and therapy of disorders in the course of which an increased activity of matrix-degrading...
|
|
|
6313169 |
Lutein esters having high bioavailability
The present invention provides an antioxidant carotenoid composition substantially free of lutein comprising lutein esters. This antioxidant composition may readily be formulated into products for...
|
|
|
6228886 |
Nutritional formulations containing water-miscible lipid derivatives as antibacterial agents
A nutritional formulation containing bactericidal amounts of diacetyltartaric acid esters of mono- and diglycerides is provided. A process of inhibiting bacterial infections including the step of...
|
|
|
6197818 |
Drug for treating diabetic nephrosis
The present invention relates new use of rhein or the salt thereof, that is new use in preparing medicine for treatment of diabetic nephropathy. A medicine containing rhein or the salt thereof for...
|
|
|
6180669 |
Method for treatment of dermatological disorders
A compound effect for the treatment of dermatological disorders comprises a mono- or diester of an α,ω-dicarboxylic acid, wherein the alcohol moiety of the said ester comprises a keratolytically...
|
|
|
6174876 |
Use of boswellic acid for treating brain tumors
The present invention relates to the use of pure boswellic acid, a physiologically acceptable salt, a derivative, a salt of said derivative or a vegetable preparation containing boswellic acid for...
|