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6703369 |
Lipase inhibiting compositions
A pharmaceutical composition contains at least one inhibitor of lipases and at least one fatty acid ester of polyol. In this composition, the fatty acid ester has a melting point above the body...
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6696490 |
Slow release insect repellent compounds and process for delivering active
Novel insect repellents having ester bonds such that when deposited on skin, natural skin cleaning agents provide slow release of the active.
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6693132 |
Methods for using alkanoyloxymethyl esters
Methods of using propionoyloxymethyl propionate (“POMP”) and butyroyloxymethyl butyrate (“BOMB”) are disclosed. Methods of treating cancer using these compounds are disclosed. The compounds...
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6680341 |
Stable pharmaceutical formulation comprising a HMG-CoA reductase inhibitor
Atorvastatin and pravastatin may be destabilized by the environmental factors, their degradation may also be accelerated by interactions with other pharmaceutical ingredients, such as fillers,...
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6673839 |
Pharmaceutical compositions with antitumour activity
Acylcarnitines, such as L-acetylcarnitine (I) were found to have marked antitumour activity, which can be further increased by simultaneous administration of somatosstatin.
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6673837 |
Acetyl L-carnitine salt with a dicarboxylic organic acid and process for preparing same
A novel solid, crystalline and non-hygroscopic substance consisting of acetyl L-carnitine acid fumarate and a process for preparing same are disclosed.
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6667341 |
Delta dicarbonyl compounds and methods for using the same
Amidomethyl esters, carbonylmercaptomethyl esters, keto-containing esters, amidomethyl thioesters, amidomethyl amides, and methylene dithioesters are disclosed. The novel compounds have two...
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6663859 |
Compositions for enhancing the immune response
D-Ribose and methods for using D-Ribose are provided for enhancing the immune response in mammals. Those with a less than optimal immune response will benefit from oral or parenteral administration...
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6653349 |
Composition for the prevention and treatment of kidney dysfunctions and diseases
A composition is disclosed which is suitable for the prevention and treatment of kidney dysfunctions and diseases and which can therefore take the form of a food supplement or of an actual...
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6649621 |
Prevention or reversal of sensorineural hearing loss (SNHL) through biologic mechanisms
The invention presents methods for preventing and treating sensorineural hearing loss and is directed to the restoration or protection of hair cells in individuals experiencing a non-presbycusis...
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6630442 |
Reparatives for chemosurgery and laser (thermal) therapy
A composition of glutathione and selenium, as a selenoamino acid or selenium yeast extract and an epidermal growth factor in a topical carrier and method of using the composition to reduce and...
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6613800 |
Method and compositions for treating psoriasis, eczema, seborrhea and arthritis
A method and composition for treating psoriasis, eczema, seborrheic dermatitis, and possibly arthritis. The present invention involves treatment of these conditions with an oral administration of a...
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6607736 |
Skin preparations for external use
An endermic liniment comprising a polyoxyethylene dicarboxylate represented by the following chemical formula (1). (In this formula, R1 and R2 are hydrogen or alkyl or branched alkyl groups...
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6608003 |
Herbicidal solutions comprising fatty acid ammonium salts and dicarboxylic acid diesters and methods of using the same
Aqueous compositions containing (i.) a salt of the formula: R 1 COO − X + (I) wherein R 1 is a C 7 to C 11 hydrocarbyl group and X is ammonium (NH 4 + ); and (ii.) a diester of the...
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6602908 |
Suppression of carcinoma using high purity conjugated fatty acid
Treatment of carcinoma in a human is disclosed, including administering a therapeutically effective amount of a fatty acid having four carbons with two conjugated double bonds formed by reacting an...
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6582941 |
Microorganisms capable of producing highly unsaturated fatty acids and process for producing highly unsaturated fatty acids by using the microorganisms
The present invention relates to the Schizochytrium genus SR21 strain and a microorganism belonging to the same species as does said SR21 strain or having substantially the same fungological...
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6545052 |
Methods and compositions for inhibiting free radical polymerization in skin and hair
A method is provided for inhibiting free radical degradation in the skin of a human or nonhuman animal comprising contacting the skin with a skin treatment composition having a concentration of a...
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6541517 |
Treatment of skin disorders
The present invention provides a method and composition for treating skin disorders, skin pathologies and pruritus, which includes applying a compound of formula (I) in a suitable formulation to...
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6534099 |
Pesticidal compositions containing menthyl salicylate
Pesticidal compositions against pests comprising menthyl salicylate. Pesticidal compositions for the control of household insects containing menthyl salicylate with one or more plant essential...
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6531143 |
α-hydroxy fatty acid derivatives and external compositions containing the same
An oily base, which has excellent stability, a low melting point and does not irritate the skin and an external composition which contains the oily base. The present invention is directed to an...
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6525097 |
Method of treating a cancerous condition by enhancing the effectiveness of the human immune system
There is disclosed a method of treating a cancerous condition in a person in need of such treatment, which comprises enhancing the effectiveness of the person's immune system by the administration...
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6515020 |
Combination of carnitines and resveratrol for prevention or treatment of cerebral and ageing disorders
A pharmaceutical product which comprises admixed or separately packaged (A) L-Carnitine or an alkanoyl L-canitine and (B) a trihydroxy- or tetrahydroxystilbene such as resveratrol is useful for the...
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6509376 |
Utilization of dialkyfumarates
The present invention relates to the use of certain dialkyl fumarates for the preparation of pharmaceutical preparations for use in transplantation medicine or for the therapy of autoimmune...
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6503945 |
Cationic amphiphiles containing N-hydroxyalkyl group for intracellular delivery of biologically active molecules
The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating...
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6500861 |
Antimicrobial composition and methods of use in the treatment of disease
A composition for eliminating an infection in a body space or cavity or on the epidermis of the body of the user is formed from an antimicrobial active agent which is, preferably, a fatty acid or...
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6488928 |
Product for topical application containing a lipase and a hydroxy acid precursor
The present invention concerns a product for topical application, capable of releasing a hydroxy acid on the skin, containing a lipase as enzyme and at least one precursor of the hydroxy acid. The...
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6465517 |
Composition for the treatment of migraine
The present invention describes a novel composition for the treatment of migraine, a common neurovascular syndrome, which can be elicited by functional and/or structural (symptomatic) disorders....
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6465515 |
Solid compositions suitable for oral administration containing non-hydroscopic salts of L-carnitine and alkanoyl L-carnitines
Non-hygrocopic salts of L-carnitine and of the lower alkanoyl L-carnitines with pamoic acid are described, which are used to prepare solid compositions suitable for oral administration. Solid...
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6458838 |
Adrenoleukodystrophy treatments
4-phenylbutyrate treatment of cells from both X-ALD patients and X-ALD knockout mice results in decreased levels of and increased β-oxidation of very-long-chain fatty acids; increased expression...
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6447811 |
Pesticide against plant-pathogenic microorganisms
A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic...
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6444700 |
Product and method to reduce stress induced immune suppression
In its broadest aspect, the present invention is directed to the discovery of immunonutritional products that are useful in reducing the immunological system suppression that results from stress....
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6441039 |
Gastro-intestinal adverse effect-free composition comprising an L-carnitine replacement
Exogenous L-carnitine in the form of an equimolar amount of L-carnitine acid fumarate is administered to reduce increased volume and fluidity of stools and frequency of bowel movements relative to...
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6436992 |
Use of fumaric acid derivatives
Disclosed is a method of treating auto-immune diseases by the administration of certain fumaric acid monoalkyl esters as salts or free acids thereof either alone or in combination with a dialkyl...
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6433017 |
Amphiphilic polyamine compounds
In accordance with the present invention, there are provided amphiphilic polyamine compounds and derivatives thereof having the property of promoting transfection of polynucleotides and...
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6426367 |
Methods for selectively occluding blood supplies to neoplasias
Disclosed are methods of selectively reducing the blood supply to a neoplastic region, such as a tumor region, thereby selectively causing necrosis of the neoplastic tissue without substantial...
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6413949 |
Prodrugs with enhanced penetration into cells
The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the...
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6414023 |
Disinfecting composition
A disinfecting composition includes about 0.01 to 2% by weight 2,4-dichlorobenzyl alcohol, about 0.1 to 10% by weight of glycerylmonolaurate, and about 95 to 99.5 % by weight vehicle such as a...
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6380244 |
Nutritional and therapeutic uses of 3-hydroxyalkanoate oligomers
Nutritional or therapeutic compositions are provided for increasing ketone body levels in the blood of mammals by providing a source of ketone bodies in the form of linear or cyclic oligomers...
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6376510 |
Neuromuscular relaxants
Alkoxy and/or acyloxy disubstituted and polysubstituted aralkyl and aralkenyl bis-quaternary ammonium derivatives of cyclic alkanol diesters have neuromuscular relaxant properties.
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6369106 |
Treatment of ischemic brain injuries with brain targeted anti oxidant compounds
A method of reducing oxidative stress in the brain of an organism having a blood brain barrier and suffering an ischemic brain injury, the method comprising the step of administering a compound to...
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6365199 |
Hair growth stimulant
A hair growth formulation. The two basic main ingredients are castor oil and a special lemon extract. The special lemon extract is made from fresh lemon peel. The peel, including the bioflavonoids...
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6365382 |
Biotechnological process for preparing hydroxylated ML-236B derivatives, known as M-4 and M-4′, and analogues thereof
The very effective conversion of ML-236B substances and derivatives thereof into 6′-hydroxylated products with the microorganisms of species Amycolatopsis orientalis , or with an extract or a...
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6359003 |
Use of fumaric acid derivatives in transplant medicine
The invention relates to the use of certain fumaric acid monoalkyl esters as salts or a free acid either alone or in combination with a dialkyl fumarate for producing pharmaceutical preparations...
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6355676 |
Fumaric acid micro tablets
The present invention relates to the use of one or more salts of fumaric acid monoalkyl esters of the general formula optionally in admixture with dialkyl fumarate of the formula wherein A is a...
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6353012 |
15-Hydroxyeicosatetraenoic acid-related compounds and methods of use
HETE derivatives and methods of their use for treating dry eye are disclosed.
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6352685 |
External preparation for skin
The object of the invention is to provide a new external preparation for skin having high melanine formation inhibition and also anti-aging effect, and desired drug effect can be obtained without...
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6348495 |
Method for treating celiac disease
A method for treating celiac disease comprising administration of a composition containing an alkanoyl L-carnitine wherein the alkanoyl group is straight or branched and has 2-6 carbon atoms and...
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6348499 |
Amphiphilic polyamide compounds
Amphiphilic polyamide compounds and derivatives thereof having the property of promoting transfection of polynucleotides and polypeptides into cells, and formulations comprising said compounds.
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6342527 |
Polymeric castor polyesters
The present invention deals with the certain castor polyesters which give high gloss when applied to the skin. The ester are the reaction of the hydroxyl group of castor oil with less than one...
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