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6864285 |
Covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids functionally active on the CB2 cannabinoid receptor
The present invention relates to novel covalent derivatives of alkanolamides of monocarboxylic and dicarboxylic acids with aminoalcohols of general formula (I) which can usefully be used as...
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6861442 |
PYK2 and inflammation
The present invention relates generally to the fields of immunology and medicine, and more specifically to the field of cellular signal transduction. The present invention relates, inter alia, to...
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6852738 |
Acyl sulfamides for treatment of obesity, diabetes and lipid disorders
A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment,...
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6852758 |
Oil composition
The invention relates to oil composition comprising 0.1 to 59.8% by weight of a triglyceride, 40 to 99.7% by weight of a diglyceride, 0.1 to 10% by weight of a monoglyceride and at most 5% by...
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6846847 |
Biocidal agents and methods of use
The present invention provides antimicrobial compositions and methods for treating medical conditions in mammals. The compositions provided herein are based on the surprising discovery that the...
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6838480 |
Composition containing sucrafate and a topical anesthetic for humans and animals and method of use thereof
A composition and method of treating plurality of conditions utilizes a combination of sucralfate and a topical anesthetic such as lidocaine. The composition finds utility in treating the symptoms...
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6838471 |
Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
A method of inhibiting the release of a proinflammatory cytokine in a cell is disclosed. The method comprises treating the cell with a cholinergic agonist. The method is useful in patients at risk...
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6806261 |
Methods for treating certain diseases using naaladase inhibitors
The present invention relates to methods for regulating the release of TGF-β from living cells in vitro or in vivo, comprising bringing the cells into contact with an effective amount of a...
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6806293 |
Use of pheromone compounds having MAP kinase modulating activity
A method of screening pheromone compounds for mitogen-activated protein (MAP) kinase modulating activity and for employing such pheromone compounds in compositions suitable for the prevention or...
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RE38604 |
Fluid therapy with L-lactate and/or pyruvate anions
Electrolyte solutions are provided which are useful in electrolyte and fluid therapy, parenteral nutrition and dialysis. The Na:Cl ratio is normalized, plasma and cellular pH are normalized and...
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6787129 |
Castor polyester as gloss agents in anionic systems
The invention relates to a blend, and a process for its use, which is made up of specific castor polyesters and anionic surfactants, which when used to clean the hair provide detergency and...
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6767922 |
IL-8 receptor antagonists
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
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6756405 |
Conjugated linoleic acid powder
A powder containing a high amount of conjugated linoleic acid or other oil is provided. The powder contains either triglycerides containing CLA, free fatty acids of CLA, or alkylesters of CLA, or...
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6756046 |
Polyol ester insecticides
The present invention relates to an environmentally acceptable synthesis method of polyol esters that produces no toxic by-products methods during the synthesis and the resultant esters are...
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6747062 |
Regulation of wound healing by nitric oxide
The present invention provides methods and compositions for promoting healing of damaged tissue that result in an increased level of nitric oxide in the vicinity of the damaged tissue. Also...
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6743821 |
Glycerol-lactate esters for use as an energy supplement during exercise and recovery
A method and lactate compound for four unique purposes: (1) the provision of a fuel energy source to skeletal muscles, hearts and other tissues and organs of humans and other mammals during...
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6740319 |
Chemical attractants for yellowjacket wasps
A combination of volatile components which act synergistically to effectively attract yellowjackets in the Vespula species group is provided. A preferred formulation includes (E)-2-hexenal and...
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6730693 |
Double salts of fumaric acid with a carnitine and an amino acid and food supplements, dietary supplements and drugs containing same
Double fumarates of L-carnitine or isovaleryl L-carnitine and an amino acid having formula (I) are disclosed which are useful as active ingredients of food supplements, dietary supplements or...
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6716876 |
Cyclopentane(ENE)heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
The invention relates to 7-[5-hydroxy-2-(hydroxyhydrocarbyl or heteroatom-substituted hydroxy hydrocarbyl)-3-hydroxy-cyclopentyl(enyl)] heptanoic or heptenoic acids and derivatives of said acids,...
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6716818 |
Caspase inhibitors and the use thereof
The present invention is directed to novel dipeptide thereof, represented by the general Formula I: where R 1 -R 3 , X and Y are defined herein. The present invention also relates to the...
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6713518 |
Non-hazardous pest control
Pesticidal compositions for the control of pests containing one or more neurally effective substances. In addition, the present invention is directed to a method for controlling pests by applying a...
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6703014 |
Attractants and repellants for colorado potato beetle
A method has been discovered for attracting Colorado potato beetles to an area of object or area, which method involves treating the object or area with a Colorado potato beetle attracting...
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6696490 |
Slow release insect repellent compounds and process for delivering active
Novel insect repellents having ester bonds such that when deposited on skin, natural skin cleaning agents provide slow release of the active.
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6696436 |
B-homoestra-1,3,5(10)-trienes as modulators of tubulin polymerization
The invention provides B-ring expanded estra-1,3,5(10)-triene compounds of general formula (1) which modulate the polymerization of tubulin and/or the depolymerization of microtubules. The...
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6677321 |
Methods and compositions for treatment of inflammatory disease
Compositions useful for treating inflammatory diseases including arthritis are disclosed which comprise cetyl myristoleate compounds or related compounds and at least one compound useful for...
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6673836 |
Vehicle for applying chemical compounds on wood
A vehicle for applying chemical compounds to wood comprises the following components in the indicated approximate percentages by weight of the total: toluene (40-70%), xylene (6-40%), benzophenone...
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6673360 |
Technique for emulsifying highly saturated hydroisomerized fluids
A preferred emulsifier blend includes ethoxylated alcohols containing hydrocarbons of C10-C16 and preferably having on average at least 2.8 ethoxy and/or alcohol groups per chain and a glycerol...
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6667340 |
Inhibitors of phosphatidyl myo-inositol cycle
The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell...
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6649176 |
Compositions containing mineral water
The present invention relates to a cosmetic composition containing mineral water and one or more compounds selected from the group of creatine, pyruvic acid, and carnitine, and cosmetically...
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6646011 |
Insect repellant compositions
The present invention relates to insect repellant compositions containing, based upon the total weight of the composition, from about 6 to about 30 percent by weight of insect repellant active...
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6635672 |
Agent for lowering prolactin
The present invention relates to a prolactin lowering drug containing at least one bicyclic diterpene of the labdane or clerodane type: wherein R1=H, C 1 to C 3 alkyl or C 1 to C 3 acyl.
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6624193 |
Preventive and therapeutic agents for eye diseases
The present invention provides a prophylactic and therapeutic medicament for ophthalmic diseases, especially ophthalmic inflammatory diseases and corneal ulcer, comprising as an active ingredient a...
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6624142 |
Trimethyl lock based tetrapartate prodrugs
The invention is directed primarily to compounds of Formula I: wherein: R 1 is a polymeric residue; L 1 is a bifunctional linking group; Y 1 and Y 2 are independently O, S or NR 7 ; R 2-7 ...
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6605447 |
Methods and means of detecting nitric oxide synthase
Methods for identifying and monitoring increased or decreased levels of inducible nitric oxide synthase in biological samples are provided. A collection device for detecting inducible nitric oxide...
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6599936 |
Anti-sebum skin care cosmetic compositions containing branched esters
Cosmetic skin care methods and compositions containing methyl-branched esters. The inventive compositions provide control of sebum secretion from sebocytes, improved oil control and improved skin...
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6599500 |
Communication disruptant and communication disruption method
When a communication disruptant containing (Z)-11-tetradecen-1-yl acetate as the only active ingredient is continually used for a period of 5 to 10 years, a phenomenon has been observed in which...
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6596300 |
Animal feed
The present invention includes a method for increasing meat production while reducing fat in ruminant and non-ruminant animals and for increasing egg production in poultry and milk production in...
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6596263 |
Cyclodextrin compositions
A composition comprising cyclodextrin and an α-hydroxy acid complexed by the cyclodextrin. A pharmaceutical preparation comprising a cyclodextrin-α-hydroxy acid complex and a pharmaceutically...
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6589521 |
Sex attractant and mating disruptant for the omniverous leafroller and orange tortrix moth
A composition of (Z)-11-tetradecenyl acetate and (Z)-11-tetradecenal in a weight ratio of about 50:50 to about 90:10 is a highly effective mating disruptant for the male Orange Tortrix and...
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6566397 |
Acyclic isoprenoid ether derivatives as chemotherapeutics
A method of and compositions for suppressing the growth of tumor cells in a patient are disclosed. In one embodiment, the method comprises treating the patient with an effective amount of an...
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6566394 |
Salicylamide derivatives
Salicylamide derivatives represented by formulae ( 1 a ) and ( 1 b ); intermediates in the production thereof; a process for producing the same; and drugs containing the same as the active...
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6562332 |
Attractants of beneficial insects
The invention provides methods and compositions useful for attracting predatory insects.
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6559181 |
Antiestrogens, process for their protection and their pharmaceutical use
This invention relates to new antiestrogens of the general formula in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure...
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6548469 |
Cleaning compositions
The present invention relates to cleaning compositions which comprise the insect repellent ethyl 3-(N-butylacetamino)propionate and the use of this insect repellent in all types of cleaning...
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6548552 |
Absorbent article, particularly a tampon having additives that reduce toxic shock syndrome toxin production
An absorbent article, particularly a tampon having additives that reduce toxic shock syndrome toxin (TST-1) production is disclosed. The tampon has a combination of an effective amount of at least...
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6540991 |
Stabilized active materials
A stabilized insect mating disruption pheromone compositions comprising an insect pheromone and 2,2′-Methylenebis(6-t-butyl-p-cresol). Methods of use and microcapsules containing these...
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6538027 |
Compositions comprising ratite oil or active fractions thereof and methods of using these composition as insect repellents
This invention provides compositions for repelling insects, particularly biting insects, such as mosquitoes, ticks, and biting flies comprising ratite oil, active fractions of ratite oil obtained...
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6534542 |
(2-hydroxy)ethyl-thioureas useful as modulators of α2B adrenergic receptors
Compounds of formula (i) and of formula (ii) wherein the symbols have the meaning disclosed in the specification, specifically or selectively modulate α 2B and/or α 2C adrenergic receptors...
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6534099 |
Pesticidal compositions containing menthyl salicylate
Pesticidal compositions against pests comprising menthyl salicylate. Pesticidal compositions for the control of household insects containing menthyl salicylate with one or more plant essential...
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6531111 |
High viscosity embolizing compositions
Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery.
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