Patents in Class 514/541

Matches 1 - 50 out of 59

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Match	Document	Document Title
1	7615575	Compounds for the treatment of metabolic disorders Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, artherosclerosis and...
2	7217706	Propanolamine derivatives This invention relates to new propanolamine derivatives or salts thereof represented by the following formula [I]: Wherein each symbol is as defined in the specification or salts thereof which...
3	6780874	Enamine derivatives Enamine derivatives of formula (1) are described: wherein R 1 is a group Ar 1 L 2 Ar 2 Alk- in, which Ar 1 is an aromatic or heteroaromatic group, L 2 is a covalent bond or a linker atom or...
4	6455539	Squaric acid derivates Squaric acid derivatives of formula (1) are described: wherein R 1 is a group Ar 1 Ar 2 Alk- in which Ar 1 is an optionally substituted aromatic or heteroaromatic group; Ar 2 is an optionally...
5	6420424	CCR-3 receptor antagonists Phenylalanine sulfonamide derivatives and their use as CCR-3 receptor antagonist.
6	6407100	Fungicidal aromatic oximes The invention relates to novel compounds of the formula in which R 1 is C 1-4 alkyl and (Y—X) is CH 2 , C 1-2 alkylthio-CH═ or C 1-2 alkyl-ON═ and Z is an aldimino or ketimino group, and...
7	6380249	HIV integrase inhibitors Certain six-membered aromatic and heteroaromatic-dioxobutyric acid derivatives are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the...
8	6211212	Pyrrolidine and thiazole derivatives with metallo-beta-lactamase inhibitory properties
9	6143776	Tosylproline analogs as thymidylate synthase inhibitors Tosylproline analogs of formula I, methods of making them, pharmaceutical compositions containing them, and methods for their use. The compounds are thymidylate synthase inhibitors; and are useful...
10	6124333	Metalloproteinase inhibitors Therapeutically active hydroxamic acid derivatives, processes for their preparation, pharmaceutical compositions containing them, and the use of such compounds in medicine. The compounds are...
11	5973006	Fluoro-substituted benzoylpropionic acid derivatives A fluoro-substituted benzoylpropionic acid compound of formula (I) either as a single optical isomer or as a mixture of optical isomers ##STR1## wherein R is hydroxy, amino, hydroxylamine, --OR',...
12	5965592	Acyl compounds Compounds of the formula ##STR1## and their salts, in which R 1 , is a C 1 -C 7 aliphatic hydrocarbon radical; X 1 is --CO; X 2 is a divalent aliphatic hydrocarbon radical which comprises an...
13	5919824	Aminophenol derivatives Aminophenol derivatives represented by the following formula (1): ##STR1## wherein X is O or S; A is alkylene, R 1 is phenyl, etc., R 2 and R 3 are H or alkyl; R 4 is substituted...
14	5916922	Phenyl glyoxamides as SPLA2 inhibitors A class of novel phenyl glyoxamides is disclosed together with the use of such compounds for inhibiting sPLA 2 mediated release of fatty acids for treatment of conditions such as septic shock.
15	5880160	Colchicine derivatives, the use thereof and formulations containing them The present invention relates to novel colchicine derivatives having antiproliferative, antineoplastic, antiinflammatory and muscle relaxant activities; said derivatives include novel colchine...
16	5723459	Biologically active acylated amino acid derivatives The present invention relates to novel compounds which possess a broad range of useful biological activities. These compounds can maintain, increase, or restore sensitivity of cells to therapeutic...
17	5705529	N-benzoyl amino acid derivatives pharmaceutical compositions containing them and process for preparing same The invention relates to novel N-benzoylamino acid derivatives of the general formula (I), ##STR1## wherein R 1 and R 2 , which are the same or different, stand for a hydroxyl group optionally...
18	5686492	Disubstituted p-fluorobenzenesulfonamides Described herein are disubstituted p-fluorobenzenesulfonamides, containing a CF 3 group, of general formula I ##STR1## which are suitable as NMR diagnostic agents.
19	5602119	Succinoylamino hydroxyethylamino sulfamic acid derivatives useful as retroviral protease inhibitors Succinoylamino hydroxyethylamino sulfamic acid derivative compounds which are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.
20	5547984	N-Acetonyl-substituted-amides Certain N-acetonyl-substituted-amides of the formula: ##STR1## wherein A is a heterocycle, a phenylalkyl, a phenylalkoxy, naphthyl, cycloalkyl, alkoxyalkyl, alkyl, haloalkyl or alkenyl group; X, Y...
21	5455271	Tight-binding inhibitors of leukotriene A.sub.4 hydrolase Inhibitors of leukotriene A 4 hydrolase are disclosed, corresponding to Formula I, below: ##STR1## wherein the depicted --NH 2 group is in the (S) configuration; --W is --CH 2 SH, --CH 2 NH 2 ...
22	5451607	Hydrazone derivatives, process for producing same, insecticides and/or acaricides containing same as active ingredient and intermediate compounds thereof There are disclosed hydrazone derivatives of the general formula [I]: ##STR1## wherein R 1 is halogen, etc.; R 2 is hydrogen or C 1 -C 6 alkyl, etc.; R 3 is hydrogen or C 1 -C 6 alkyl, etc.;...
23	5389619	Derivatives of phenylacetic acid, their preparation and their use as pesticides Compounds of the formula I ##STR1## where n, W, X, Y, Z, R 1 , R 2 , and R 3 are as defined herein exhibit fungicidal, insecticidal, and acaracidal activity.
24	5344841	Bis-(hydroxylakylamino)-anthraquinone inhibitors of protein kinase C
25	5296501	2,6-diamino-heptandedioic acids A compound selected from the group consisting of a compound of the formula ##STR1## wherein the dotted lines indicate an optionally endo or exo double bond, Y is selected from the group consisting...
26	5231113	Tetralin esters of phenols or benzoic acids having retinoid like activity Retinoid-like activity is exhibited by compounds of the formula ##STR1## where the R groups are independently hydrogen, or lower alkyl; A is --C(O)O--, --OC(O)--, --C(O)S--, or --SC(O)--; n is 0-5;...
27	5175170	β-amino acid derivatives Non-peptidyl compounds characterized generally as cycloalkyl/cycloalkylkyl-N-terminal amino hydroxy β-amino acid derivatives are useful as renin inhibitors for treatment of hypertension. Compounds...
28	5140044	UCN-1028D derivatives A UCN-1028D derivative represented by the formula: ##STR1## has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.
29	5109000	Thiol carboxylic acid derivatives and their use as collagenase inhibitor Novel compounds of the formula (I), processes for their preparation and their use as collagenase inhibitors are described: ##STR1## in which R 1 is hydroxy; alkoxy; aryloxy; aralkyloxy; --NR 6 R...
30	5043338	Fungicide compositions The invention relates to synergistic combinations of known fungicide active ingredients and their application in plant protection.
31	5021454	Benzoylaminoalkanoic acids and esters Benzoylaminoalkanoic acids and esters thereof are fungitoxic and useful for controlling fungi, particularly phytopathogenic fungi.
32	5017608	Hydrocinnamic acid derivatives Hydrocinnamic acid derivatives of the formula ##STR1## wherein one or two of the symbols R 1 to R 4 are halogen or methoxy and the others are hydrogen; R 5 is hydrogen or phenyl; R 6 is a...
33	5011854	Hydroxamic acid derivatives and use thereof in combatting lipoxygenase-mediated diseases A hydroxamic acid compound represented by the general formula (I) or a salt thereof; ##STR1## wherein R 1 represents a hydrogen atom, or a substituted or unsubstituted alkanoyl group, R 2 ...
34	4975460	Indanoxyacetic acid derivatives Novel indanoxyacetic acid derivatives of the formula: ##STR1## wherein R 1 is a lower alkyl group, a substituted or unsubstituted phenyl group, naphtyl group or a sulfur-containing heterocyclic...
35	4937243	Thiol carboxylic acid derivatives and their use as colagenase inhibitors Novel compounds of the formula (I), processes for their preparation and their use as collagenase inhibitors are described: ##STR1## in which R 1 is hydroxy; alkoxy; aryloxy; aralkyloxy; --NR 6 R...
36	4923888	Butenoic acid amides, their salts, and pharmaceutical compositions containing them The present invention relates to novel compounds of the general formula (I), ##STR1## wherein R stands for hydrogen, halogen, C 1 -4 alkyl, C 1 -4 alkoxy or C 1 -4 acylamino group; R 1 means...
37	4916157	Acylated naphthylamines as plant fungicides There are described novel acylated naphthylamines of the formula I defined herein ##STR1## which have valuable fungicidal properties. They can be used in practice on their own or in the form of...
38	4914128	Acrylates and fungicides which contain these compounds Acrylates of the general formula ##STR1## where R 1 and R 2 independently of one another are each C 1 -C 8 -alkyl, X is hydrogen, C 1 -C 4 -alkyl, halogen, C 1 -C 4 -alkoxy, haloalkyl,...
39	4906666	Hydroxamic acids and pharmaceutical compositions containing them, and anti-allergic use thereof The present invention provides compounds of the general formula: ##STR1## wherein Ar is a phenyl radical optionally substituted by alkyl, alkenyl, alkoxy, alkylthio, alkanoyl, hydroxyl,...
40	4883815	Hydrocinnamic acid derivatives Hydrocinnamic acid derivatives of the formula ##STR1## wherein one or two of the symbols R 1 to R 4 are halogen or methoxy and the others are hydrogen; R 5 is hydrogen or phenyl; R 6 is a...
41	4882341	Amino substituted propenoates and their use as fungicides The invention relates to amino substituted propenoates and their use against fungi.
42	4782089	2-amino-3-aroyl-gamma-oxobenzenebutanoic acids and esters 2-Amino-3-aroyl-γ-oxobenzenebutanoic acids and derivatives having the formula: ##STR1## wherein X is hydrogen, halogen, or loweralkyl; Y is hydrogen, halogen, loweralkyl, loweralkoxy, nitro, or...
43	4639468	Derivatives of glycinamide, their preparation and their use A glycinamide derivative of the general formula I: ##STR1## wherein: R is a linear or ramified alkyl group C 5 -C 18 , a linear or ramified alkenyl group C 5 , C 6 , C 7 , C 8 , C 9 , C 10 , C 11...
44	4621098	Thioethers and pharmaceutical compositions containing them The present invention provides thioethers of the general formula: ##STR1## wherein Ar is a phenyl radical which is optionally substituted one, two or three times by alkyl, alkenyl, alkoxy,...
45	4621099	Polyene compounds useful in the treatment of allergic responses Polyene compounds represented by the formula ##STR1## in which R is H, lower alkyl of from 1 to 8 carbon atoms or aralkyl; R 1 is H or lower alkyl of from 1 to 5 carbon atoms; and Y is...
46	4619944	Antihypertensive compounds Provided are antihypertensive compounds of the formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are hydrogen, alkyl, alkenyl, alkynyl, phenyl-alkyl, or cycloalkyl, and may be the...
47	4570006	Amidine compound, process for producing same and anti-complement agent comprising same Amidino compounds represented by the formula ##STR1## and pharmaceutically acceptable acid addition salts thereof are novel compounds and are useful as powerful anti-trypsine, anti-plasmin,...
48	4568684	N-Substituted 2-methylnaphthylamides, their preparation, and fungicides containing these compounds N-substituted 2-methylnaphthylamides of the general formula I ##STR1## where R is an unsubstituted or substituted furyl, isoxazolyl, oxazolyl, isothiazolyl, thiazolyl, 1,2,4-oxadiazol-3-yl,...
49	4537906	Substituted phenylalkenoic acids and esters Substituted phenylalkenoic acids and esters of the formula: ##STR1## having useful pharmaceutical activity are disclosed.
50	4486429	Amino derivatives of 4-phenyl 4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and methods for preparing and therapeutically using them Compounds of the formula I: ##STR1## in which R represents a hydrogen atom or an alkyl radical containing from 1 to 8 carbon atoms and R 1 and R 2 , which may be identical or different...

Matches 1 - 50 out of 59

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