Patents in Class 514/540

Matches 1 - 50 out of 81

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Match	Document	Document Title
1	7585846	Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof Disclosed are hydrophilic choline/N-heterocycle ester compounds containing single amino acids, peptides, or derivatives thereof which have the potential to express anti-oxidant activity capable of...
2	7419998	Therapeutic methods and compositions involving isoflavones Therapeutic methods of treatment, compositions and foodstuffs are described which contain isoflavone compounds described by general formula (I), in which Z is H, R 1 is H, or R A CO where R A is...
3	7208521	Selective inhibitors of the urokinase plasminogen activator The present invention relates to novel selective inhibitors of the urokinase plasminogene activator (uPA, EC3,4.21.31) of the aryl guanidine type.
4	7208520	Crystals of hydroxynorephedrine derivative The present invention provides ethyl (−)-2-[4-[2-[[(1S,2R)-2-hydroxy-2-(4-hydroxyphenyl)-1-meth ylethyl]amino]ethyl]-2,5-dimethylphenoxy]acetate hydrochloride, crystalline forms thereof and...
5	6998418	Acellular biological material chemically treated with genipin A method for promoting autogenous ingrowth of damaged or diseased tissue selected from a group consisting of ligaments, tendons, muscle and cartilage, the method comprising a step of surgically...
6	6946486	Quaternary ammonium compounds The invention features quaternary ammonium compounds of formula I, described herein, and their use in treating asthma, chronic obstructive pulmonary disorder, allergic rhinitis, and infectious...
7	6835719	Pesticidal composition An environmentally safe pesticidal liquid suspension composition including a mixture of sulfur combined with pyrethrins and/or pyrethroids is provided. The pesticidal composition is effective to...
8	6469063	Inhibition of inflammation via inhibition of COX-2 gene transcription The present invention is directed to a method of treating inflammation comprising administering to a subject in need thereof an amount of a caffeic acid derivative sufficient to inhibit the...
9	6458837	Lipophilic diesters of chelating agents The invention discloses stable diesters of chelating agents of divalent metal ions, processes for their preparation and pharmaceutical compositions thereof. Most preferred compounds according to...
10	6451786	3′-epimeric k-252a derivatives Compounds defined by the following general structure are disclosed: These compounds display pharmacological activities, including inhibition of tyrosine kinase activity and enhancement of the...
11	6350781	Method and analgesic preparations for sustained and extended corneal analgesia with subanesthetic concentrations of lidocaine A preparation suitable for sustained and extended corneal analgesia and for repeated administration consisting of subanesthetic concentrations of lidocaine. A method for corneal analgesia by...
12	6294582	Methods for treatment of asthma using S-oxybutynin Substantially optically pure S-oxybutynin, or a pharmaceutically acceptable salt thereof, is administered as a treatment for asthma. Such treatment is provided while reducing the adverse effects...
13	6274570	Pesticidal compositions A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a)...
14	6218428	Ophthalmic composition The current invention is an ophthalmic composition that combines multiple agents necessary to perform a routine eye examination. Preferably, the composition is a mixture of a topical local...
15	6153647	Method for augmenting the inotropic effects of β-adrenergic agonists using pyruvate therapy A method for treating medical patients suffering from cardiac trauma by co-administering pyruvate with a β-adrenergic agonist. This method for treating cardiac trauma, such as ischemic reperfusion...
16	6114382	Methods for treating inflammatory bowel disease The present invention provides novel compositions and methods relating to the treatment of Inflammatory Bowel Disease ("IBD"), most notably, Ulcerative Colitis, Crohn's Disease, Colitis and...
17	6043284	Anti-atherosclerotic diaryl compounds The present invention is concerned with diaryl compounds of formula (I) and their use in medical therapy, particularly in the prophylaxis or treatment of a clinical condition for which an ACAT...
18	6004992	Aminocarboxylic acid fluorobutenyl esters The present invention relates to novel fluorobutenyl aminocarboxylates of the formula (I) R--CO--O--CH 2 --CH 2 --CXCF 2 (I) in which X represents hydrogen or halogen and R...
19	5985824	Methods and compositions for treating cystic fibrosis Methods and compositions for treating CF by mobilizing mutant forms of CFTR, which retain at least some functional activity, to the plasma membrane where they can mediate chloride ion transport are...
20	5955505	Glutamic acid receptor agonist A method comprising administering a sulfonamide derivative to a patient requiring activation of glutamate receptors, the sulfonamide derivative represented by the formula ##STR1## wherein A is a...
21	5919824	Aminophenol derivatives Aminophenol derivatives represented by the following formula (1): ##STR1## wherein X is O or S; A is alkylene, R 1 is phenyl, etc., R 2 and R 3 are H or alkyl; R 4 is substituted...
22	5861435	Method for preventing settlement of aquatic fouling organisms A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to...
23	5837713	Treatment of eosinophil-associated pathologies by administration of topical anesthetics and glucocorticoids A therapeutic method is provided to treat an eosinophil-associated pathology, such as bronchial asthma, by administering to a mammal in need of such treatment, an effective amount of at least one...
24	5760077	Topical ophthalmic analgesic preparations for sustained and extended corneal analgesia A preparation suitable for sustained and extended corneal analgesia and for repeated administration consisting of ultralow nontoxic subanaesthetic concentrations of local anesthetic agents. A...
25	5637613	15-deoxyspergualin analogs, their method of preparation and their use in therapeutics The present invention relates, by way of novel industrial products, to compounds which are structurally related to 15-deoxyspergualin and which have the formula ##STR1## in which: A is a single...
26	5631267	Method for the treatment of eosinophil-associated diseases by administration of topical anesthetics A therapeutic method is provided to treat eosinophil-associated hypersensitivity diseases, such as bronchial asthma, by locally administering to a mammal in need of such treatment, an effective...
27	5610184	Method for sustained and extended corneal analgesia A method for sustained and extended corneal analgesia by repeated administration of ophthalmic analgesic solutions or preparations containing ultralow nontoxic subanesthetic concentrations of local...
28	5550155	Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures Monofucosylated and monosialyated derivatives of the compound βGal(1-4)βGlcNAc(1-3)βGal(1-4)βGlcNAc-OR, where R is hydrogen, a saccharide, an oligosaccharide or an aglycon moiety have been...
29	5482961	Soft β-adrenergic blocking agents New soft β-adrenergic blocking agents, useful in the treatment or prevention of cardiovascular disorders and in the treatment of glaucoma, have the formula ##STR1## wherein n is an integer from 0...
30	5451607	Hydrazone derivatives, process for producing same, insecticides and/or acaricides containing same as active ingredient and intermediate compounds thereof There are disclosed hydrazone derivatives of the general formula [I]: ##STR1## wherein R 1 is halogen, etc.; R 2 is hydrogen or C 1 -C 6 alkyl, etc.; R 3 is hydrogen or C 1 -C 6 alkyl, etc.;...
31	5446067	Oxime ethers and fungicides containing them Oxime ethers of the formula ##STR1## wherein m, G, R, R 1 , X, Y, and Z are as defined herein and fungicides containing these compounds.
32	5446065	Sulfonamides of phenylalkylamines or phenoxyalkylamines processes for their preparation and medicaments containing these compounds Compounds of the formula I ##STR1## in which R 1 signifies an aryl, aralkyl or an aralkenyl group, the aryl radical of which can, in each case, be substituted one or more times by halogen, cyano,...
33	5414017	Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same Compounds of the formula ##STR1## wherein m is zero or 1; n is zero, 1 or 2; p is zero or 1 to 6 provided that m and p are not both zero; R 3 is hydrogen, acyl, or benzyl; and R 1 is hydrogen,...
34	5346887	Glaucoma treatment A method and a composition for treating or reducing and/or controlling intraocular pressure comprising administering an effective amount of a renin inhibiting compound of the formula: ##STR1##...
35	5344844	Salt excretion promoting composition A salt-excretion promoting composition, characterized by containing (i) 10 parts by weight of agar and (ii) 1 to 15 parts by weight of at least one polysaccharide selected from the group consisting...
36	5294641	Method for treating a medical patient for cardiac trauma A method for treating a medical patient prior to or during heart trauma, e.g., myocardial infarction, angina and ischemia. An effective dosage of pyruvate is introduced into the patient to increase...
37	5278148	Amino acid derivatives useful for treating high blood pressure Compounds of the formula ##STR1## wherein R 1 is hydrogen or methyl, R 2 is ethyl, propyl, isopropyl, imidazol-2-yl, imidazol-4-yl, pyrazol-3-yl, thiazol-4-yl, thien-2-yl, ethoxycarbonyl,...
38	5262436	Acylamino acid antihypertensives in the treatment of congestive heart failure Mercapto-acylamino acids useful in the treatment of hypertension and combinations of mercapto-acylamino acids and atrial natriuretic factors or angiotensin converting enzyme inhibitors useful for...
39	5238958	Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals The present invention is novel substituted α-amino acids, pharmaceutical compositions, methods of use, and preparations therefore having utility for treating disorders which benefit from blockade...
40	5151414	Phenoxyethyl amine compounds active on the cardiovascular system Compounds of formula ##STR1## (wherein R, R 1 , R 2 , R 3 , n, m and p have the meanings reported in the specification), their preparation and the compositions for pharmaceutical use containing...
41	5124322	Dipeptide collagenase inhibitors Novel compounds of formula (I), salts, solvates and hydrates thereof: ##STR1## in which: R 1 and R 2 are independently hydrogen; alkyl; alkoxy; halogen; or CF 3 ; R 3 is hydrogen; acyl, such...
42	5104897	Medical uses of halogen substituted diphenylsulfides A class of halogen-substituted diphenylsulfide compounds are disclosed which produce a large selective inhibition of serotonin uptake in brain. Such compounds are useful in the treatment of...
43	5075335	Guanidinobenzoic ester derivative A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and...
44	5053525	Oxo-analogs of mevinolin-like antihyper-cholesterolemic agents Mevinolin-like compounds in which the lactone is opened and the hydroxyl function produced thereby is replaced by an oxo function are potent HMG-CoA reductase inhibitors possessing one less...
45	5051448	GABA esters and GABA analog esters Ester derivatives of gamma-aminobutyric acid (GABA) and GABA analogues which cross the blood-brain barrier are disclosed, as well as methods of synthesizing and using the compounds. The ester...
46	5047410	Indolyl derivatives and their use as 5-HT.sub.3, receptor antagonists New pharmacologically active amidino and guanidino derivatives which are 5-HT 3 receptor antagonists useful as antiemetic, gastric prokinetic and antimigrainic agents of the following general...
47	5017608	Hydrocinnamic acid derivatives Hydrocinnamic acid derivatives of the formula ##STR1## wherein one or two of the symbols R 1 to R 4 are halogen or methoxy and the others are hydrogen; R 5 is hydrogen or phenyl; R 6 is a...
48	5001128	HMG-COA reductase inhibitors Disclosed are novel 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy...
49	4997642	Stable oil-in-water emulsions Oil-in-water emulsions containing polyvinyl alcohol, surfactant and a salt with improved freeze-thaw and elevated temperature storage stability.
50	4946863	CNS-affecting 6-oxy-3-aminomethyl indanes, compositions thereof, and method of treating therewith The present invention relates to 3-aminomethyl derivatives of indane, dihydrobenzofurane, dihydrobenzothiophene, and indoline, acid addition salts thereof, isomers thereof, methods of preparation,...

Matches 1 - 50 out of 81

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