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8183229 |
Bone filling complex and method for fabricating the same
Provided is a bone filling complex and method of preparing the same. The bone filling complex includes a matrix including a hydrogel-type hyaluronic acid derivative; and a bone derivative filling...
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8182831 |
Stable and taste masked pharmaceutical dosage form using porous apatite grains
A stable and taste masked pharmaceutical dosage form includes porous apatite grains and a drug entrapped in pores of said grains, wherein said grains have a size of 0.1-1000 μm and said pores of ...
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8183228 |
Anticoagulant antithrombotic dual inhibitors comprising a biotin label
The present invention relates compounds of the formula: oligosaccharide-spacer-(GpIIb/IIIa antagonist), wherein the oligosaccharide is a negatively charged oligosaccharide residue comprising four...
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8182464 |
Method for intravesical drug delivery
Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube...
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8178512 |
Methods and compositions for treating diseases and disorders associated with siglec-8.
The invention provides therapeutic methods and compositions for the prevention and treatment of Siglec-8 associated diseases and disorders such as asthma and allergic reactions. In particular, the...
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8178511 |
Method of administering hyaluronan formulation for the amelioration of osteopenia
Disclosed is a method for the amelioration of resorptive bone loss in osteopenia including administering to a subject a therapeutically effective amount of an exogenous hyaluronan formulation.
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8168612 |
Injectable cross-linked polymeric preparations and uses thereof
A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature...
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8168613 |
Injectable cross-linked polymeric preparations and uses thereof
A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature...
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8168599 |
Composition and method for healing tissues
The composition and method for healing tissues is a medicinal composition for facilitating the growth, protection and healing of tissues and cells in animals and humans. The composition is...
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8163715 |
Inulin of very high chain length
The invention relates to a long-chain inulin and its preparation from artichoke roots, to its use in foodstuffs and cosmetic preparations and to foodstuffs and cosmetic preparations which comprise...
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8163714 |
Injectable crosslinked and uncrosslinked alginates and the use thereof in medicine and in cosmetic surgery
The invention relates to the use of implantable microcapsules, or microparticles or gels produced from alginates that are crosslinked with bivalent or multivalent cations or that are uncrosslinked,...
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8163716 |
Method of administering hyaluronan formulation for the amelioration of osteophytes
Disclosed is a method for the amelioration of osteophyte formation including administering to a subject a therapeutically effective amount of an exogenous hyaluronan formulation.
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8158608 |
Bioactive fraction from Zingier officinale and a process for the preparation thereof
Ulcer is a serious oxidative stress induced disease with complex pathologic events including upregulation of H+K+ ATPase of parietal cell (PC) membrane, damage of mucin layer around PC, PC-DNA...
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8153613 |
Barrier film-forming germicidal composition for controlling mastitis
A long-lasting persistent, uniform film-forming skin protecting germicidal composition provides a long-lasting persistent barrier film when applied to skin. The compositions have particular utility...
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8153591 |
Protein biomaterials and biocoacervates and methods of making and using thereof
The present invention relates to protein biocoacervates and biomaterials and the methods of making and using protein biocoacervates and biomaterials. More specifically the present invention relates...
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8153135 |
Polysaccharide-polypeptide conjugate
Disclosed is a method of producing a polysaccharide-polypeptide conjugate by reacting a polysaccharide with a polypeptide which contains at least one free amino group, wherein a polysaccharide...
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8148350 |
Carbohydrate composition for flat glucose response
A low-glycemic available carbohydrate composition of the invention contains the following components: (i) 5-60 wt. % of one or more monosaccharides selected from monosaccharides other than glucose...
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8148351 |
Enteropathy ameliorating composition
The present invention relates to a composition for preventing, ameliorating or treating a bowel disease, comprising galactomannan and/or arabinogalactan; a liquid food for preventing, ameliorating...
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8143235 |
Use of dietary fibres against muscle wasting
A composition nutritional containing dietary fibres is useful for the treatment of muscle wasting, if the dietary fibre comprise at least 30 wt. % of galacto-oligosaccharides or other...
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8142785 |
Method or use of a solubilized glucan product to increase immunostimulation in animals
β-(1-6)-Glucanase treatment of glucan from yeast cells, pure or feed grade especially yeast from the family Saccharomyces and particularly Saccharomyces cerevisiae, provides a novel glucan product ...
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8138163 |
Aldehyde conjugated flavonoid preparations
There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8...
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8137688 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A synthetic nucleus pulposus is provided that is useful in treatment of degenerative disc disease, augmentation of a degenerate disc, and alleviation of back pain. In an embodiment the synthetic...
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8138265 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network...
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8137696 |
Biomimetic composition reinforced by a polyelectrolytic complex of hyaluronic acid and chitosan
The present invention relates to a three dimensional, malleable cell culture composition and method of forming the same comprising hyaluronic acid, chitosan and a polyelectrolytic complex of...
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8133881 |
Carbohydrate conjugates to prevent abuse of controlled substances
The invention provides a “street-safe” version of a controlled substance that permits the therapeutically beneficial effects of the substance while reducing or eliminating the euphoric effects tha...
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8128905 |
Stabilized uncoated particles of reversed liquid crystalline phase materials
Uncoated particles of reversed cubic phase or reversed hexagonal phase material containing an active disposed within are provided. The uncoated particles have an ionic charge that is sufficient to...
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8128906 |
Stabilized uncoated particles of reversed liquid crystalline phase materials
Uncoated particles of reversed cubic phase or reversed hexagonal phase material containing an active disposed within are provided. The uncoated particles have an ionic charge that is sufficient to...
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8129359 |
Composition and method for treating post-surgical pain
A composition for reducing pain at a surgical wound site or trauma site comprising oxidized regenerated cellulose and a non-steroidal anti-inflammatory drug or pharmaceutically acceptable salt or...
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8119155 |
Nutrition with lipids and non-digestible saccharides
The invention relates to a liquid nutrition comprising short chain fatty acyl chains, polyunsaturated fatty acyl chains, vegetable oil and a non-digestible, fermentable saccharide. The composition...
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8119167 |
Food supplement composition suitable for promoting iron absorption
Use of a composition comprising cartilage or chondroitin sulphate and absorbable zinc for the preparation of a food supplement or a drug suitable for promoting iron absorption in patients suffering...
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8119596 |
Composition with anti-inflammatory, protein synthesizing, enzyme deficiency activating genetic therapy and anti-cancer activity and methods of use
A composition for treating damaged tissue and promoting healthy tissue growth, healing and tissue regeneration, wherein said composition comprises an extracellular matrix compound, a surface-active...
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8119615 |
Methods and kits for folding proteins
The invention relates to methods for folding protein comprising providing an aqueous solution of a protein in non-native conformation and a linear or branched sugar polymer comprising three or more...
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8114855 |
Low density cosmetic formulations, cosmetic products containing the same and methods of treating hair, nails and/or skin using the same
Low density cosmetic formulations which comprise: (a) a cosmetic mixture; and (b) a gas incorporated in the cosmetic mixture; wherein the cosmetic mixture comprises (i) an alk(en)ylpolyglycoside,...
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8114856 |
Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
The present invention is directed to analogs of aminoglycoside compounds as well as their preparation and use as prophylactic or therapeutics against microbial infection.
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8110561 |
Injectable cross-linked polymeric preparations and uses thereof
A therapeutic composition for treatment of a body tissue which includes an aqueous solution of a cross-linked polymer being capable of: (i) maintaining a liquid state in storage at room temperature...
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8105391 |
Merhods of treatment with devices having a coating containing pegylated hyaluronic acid and a pegylated non-hyaluronic acid polymer
Provided herein are a method, which comprises implanting in a patient an implantable device comprising a coating that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid...
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8106030 |
Hemostatic material
A hemostatic powder comprises a chitosan salt together with at least one inert material. The disclosure also relates to hemostatic powders into which fluid penetrability is 0.5 cm or more within 1...
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8101196 |
Polysaccharide biomaterials and methods of use thereof
The invention includes a medical hydrogel made from polymerized polysaccharide macromers. The macromers are preferably polysaccharides decorated with polymerizable groups, for example,...
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8097591 |
Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
The present invention relates to compositions and methods of their production and use, including use in increasing de-N-acetyl sialic acid antigen of a mammalian cell and methods that exploit the...
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8097277 |
Charge-dynamic polymers and delivery of anionic compounds
The present invention provides dynamic charge state cationic polymers that are useful for delivery of anionic molecules. The dynamic charge state cationic polymers are designed to have cationic...
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8092780 |
Polyvalent conjugate vaccine for cancer
This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated...
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8092818 |
Medical devices having bioactive surfaces
According to an aspect of the present invention, medical devices are provided, which contain (a) a substrate and (b) a polymeric region disposed over the substrate which contains at least one block...
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8088605 |
Exopolysaccharides delivery system for active molecules
The present invention relates to a delivery system for delivery of an active molecule to a patient, the delivery system comprising a population of exopolysaccharide micelles, each micelle defining...
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8088369 |
Anti-wrinkle agent
The invention provides an anti-wrinkle agent which has an excellent effect of inhibiting the formation of wrinkles and excellent safeness. The anti-wrinkle agent contains, as an active ingredient,...
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8084440 |
Method for improving the fertility of animals
This invention is in the field of animal food, in particular food for female animals in their reproductive phase. Food according to the invention improves the fertility of animals and increases...
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8084441 |
Cystitis treatment with high dose chondroitin sulfate
Interstitial cystitis and related GAG-deficient conditions of the bladder and urinary tract are treated by instillation of high dose chondroitin sulfate, such as 400 mg/20 mL. The higher dose of...
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8080590 |
Porous polymeric matrices made of natural polymers and synthetic polymers and optionally at least one cation and methods of making
A porous polymeric matrix containing at least one natural polymer and at least one synthetic polymer and optionally at least one cation. Furthermore, a method of making a porous polymeric matrix...
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8080535 |
Hyaluronic acid nutritional supplements and methods of using the same
Hyaluronic acid nutritional supplements and methods of using the same. In at least one embodiment of a nutritional supplement of the present disclosure, the nutritional supplement comprises a...
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8076313 |
Composition containing fermentable polysaccharides
The present invention relates to a composition to a nutritional composition comprising 0.1 to 15 gram fermentable e partially hydrolysed gum having a degree of polymerization between 10 and 300 per...
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8076312 |
Use of lipid conjugates in the treatment of disease
This invention provides a method of preventing asthma, allergic rhinitis, or chronic obstructive pulmonary disease in a subject comprising the step of administering to a subject a compound...
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