|
Match
|
Document |
Document Title |
|
|
7585895 |
Therapeutic substituted cyclopentanes
Therapeutic prostaglandin compounds are disclosed herein.
|
|
|
7563924 |
9-chloro-15-deoxyprostaglandin derivatives, process for their preparation and their use as medicaments
The present invention relates to 9-chloroprostaglandin derivatives of the general formula I which may be advantageous for the treatment of fertility problems.
|
|
|
7498360 |
Method and compositions for local treatment of Meniere's disease, tinnitus and/or hearing loss
A novel method and compositions for the local treatment of Meniere's disease, tinnitus and hearing loss are described. The treatment is based on the administration of a therapeutically effective...
|
|
|
7452556 |
Compositions for the treatment of pilosebaceous gland inflammations comprising aluminum fluoride
The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and...
|
|
|
7425651 |
Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof
The present invention provides novel jasmonate derivative compounds, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and...
|
|
|
7388029 |
Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss,...
|
|
|
7365097 |
Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent
Disclosed herein is the cosmetic use, as a desquamating agent, of at least one (dihydro)jasmonic acid derivative of a given formula. Further disclosed herein is a cosmetic method for smoothing the...
|
|
|
RE39609 |
8-iso-prostaglandins for glaucoma therapy
The present invention relates to the use of 8-iso prostaglandins and their derivatives for decreasing intraocular pressure, for example in the treatment of glaucoma It is based, at least in part,...
|
|
|
7202275 |
Malonamic acids and derivatives thereof as thyroid receptor ligands
The present invention relates to novel thyroid receptor ligands and, more particularly, relates to malonamic acids and derivatives thereof of Formula I, which are useful in the treatment of...
|
|
|
7176238 |
Nitrostated and nitrosylated prostaglandins, compositions and methods of use
The present invention describes novel nitrosated and/or nitrosylated prostaglandins, and novel compositions comprising at least one nitrosated and/or nitrosylated prostaglandin, and, optionally, at...
|
|
|
7163959 |
Prostagladin derivatives for the treatment of glaucoma or ocular hypertension
The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin...
|
|
|
7141607 |
Methods and compositions for treating and inhibiting retinal neovascularization
Methods and compositions for the prophylactic and therapeutic treatment of retinal disorders associated with neovascularization using topical ophthalmic compositions comprising hydroxamic acid...
|
|
|
7141606 |
Gabapentin analogues for sleep disorders
The invention provides a new use of compounds for formula 1 or 1A or a pharmaceutically acceptable salt thereof. The compounds are useful in the treatment of insomnia and related disorders.
|
|
|
7129272 |
Apoptosis inhibitor
Disclosed is a method for treatment of a subject having a disease or condition associated with apoptosis, which comprises administering to the subject an effective amount of a 15-keto-prostaglandin...
|
|
|
7084178 |
Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives
A series of N-cycloalkylcarboxamide derivatives of N-benzyl benzenesulfonamides of Formula I are described.
The compounds inhibit β-amyloid peptide (β-AP) production and are useful in the...
|
|
|
7074827 |
Method for treating ocular hypertension and glaucoma
Provided is a method for treating ocular hypertension and glaucoma with reduced side effects such as keratoconjunctive disorders and macular edema, which comprises administering an ophthalmic...
|
|
|
7053119 |
Methods for identifying and using IKK inhibitors
The present invention provides methods and compositions for inhibiting IKK, as well as methods and compositions for identifying compounds with activity as inhibitors of IKK, and methods and...
|
|
|
7049340 |
Neuroprotective and retinoprotective ophthalmologic drugs
The invention concerns a neuroprotective and retinoprotective medicine, whereof the active principle is selected among a group of compounds consisting of ramipril, ramiprilat or any other...
|
|
|
6982283 |
Method for treating drug-induced constipation
Provided is a method for treating drug-induced constipation comprising a step of administering an effective amount of a 15-keto-prostaglaindin compound to a subject suffering from drug-induced...
|
|
|
6981684 |
Post support apparatus with rotatable post guide
An apparatus for supporting a metal post while it is being driven into the ground utilizes a platen base and a guide member which is rotatably joined to the base for holding the post in a steady...
|
|
|
6972294 |
Compounds, their preparation and use
Disclosed are novel compounds of formula (I)
wherein A 1 , A 2 , Ar, R 5 , R 6 , R 8 , M, Q, Y, Z, k, m and n are as defined in the specification. These compounds are useful in the treatment...
|
|
|
6958146 |
Compounds to affect insect behavior and to enhance insecticides
Various exemplary compounds, compositions and methods are disclosed. An exemplary composition includes an insecticide comprising a formula weight greater than approximately 220 and a compound...
|
|
|
6956057 |
EP4 agonists as agents for lowering intraocular pressure
The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective...
|
|
|
6956056 |
Method for providing a cathartic effect
The present invention relates to a novel method for providing a cathartic effect to a patient in need of cathartic induction, which comprises administering to the patient a cathartic-inducing...
|
|
|
6933289 |
Inhibition of irritating side effects associated with use of a topical ophthalmic medication
This invention relates to a method of reducing an irritating or adverse side effect associated with the topical use of an active ophthalmic drug comprising incorporating an effective amount of a...
|
|
|
6921774 |
Compounds and their use as glycine transport inhibitors
The invention provides novel compounds of the formula I below:
wherein the meaning of each substituent is defined in the application. The compounds are useful as inhibitors of the glycine...
|
|
|
6884819 |
Neuropathy remedies
The present invention provides a neurodegenerative disease therapeutic agent containing as its active ingredient a (15R)-isocarbacycline derivative indicated by the following formula [I] or a...
|
|
|
6875787 |
10,10-dialkyl prostanoic acid derivatives as agents for lowering intraocular pressure
The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective...
|
|
|
6858650 |
Stable salts of novel derivatives of 3,3-diphenylpropylamines
The present invention concerns highly pure, crystalline, stable compounds of novel derivatives of 3,3-diphenylpropylamines in the form of their salts, a method for the manufacture and highly pure,...
|
|
|
6849649 |
N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase
The invention relates to compounds of formula (I) for treating for example sexual dysfunction, wherein R 1 is optionally substituted C 1-6 alkyl, optionally substituted carbocyclyl, optionally...
|
|
|
6825232 |
Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
The topical use of HETE compounds to treat ophthalmic inflammatory disorders involving cytokines is disclosed.
|
|
|
6780874 |
Enamine derivatives
Enamine derivatives of formula (1) are described: wherein R 1 is a group Ar 1 L 2 Ar 2 Alk- in, which Ar 1 is an aromatic or heteroaromatic group, L 2 is a covalent bond or a linker atom or...
|
|
|
6770675 |
Compositions and methods for reducing ocular hypertension
An improved ophthalmic composition, including docosanoid active agents, which is especially useful in lowering intraocular pressure associated with glaucoma. Improvements in IOP reduction efficacy,...
|
|
|
6767920 |
3, 7 or 3 and 7 thia or oxa prostanoic acid derivatives as agents for lowering intraocular pressure
The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective...
|
|
|
6723748 |
Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions...
|
|
|
6716876 |
Cyclopentane(ENE)heptenoic or heptanoic acids and derivatives thereof useful as therapeutic agents
The invention relates to 7-[5-hydroxy-2-(hydroxyhydrocarbyl or heteroatom-substituted hydroxy hydrocarbyl)-3-hydroxy-cyclopentyl(enyl)] heptanoic or heptenoic acids and derivatives of said acids,...
|
|
|
6710081 |
Erection insufficiency remedies
Therapeutic agents for erectile dysfunction containing as the active ingredient prostaglandin derivatives of formula (I) (wherein symbols have the same meanings as described in the description),...
|
|
|
6683071 |
Initiation of oestrus
This invention relates to a method for the initiation of oestrus and ovulation early postpartum, especially but not exclusively, in dairy cows which comprises supplying a prostaglandin post partum...
|
|
|
6680339 |
15-fluoro prostaglandins as ocular hypotensives
15-fluoro substituted analogs of PGF 2α and methods of their use in treating glaucoma and ocular hypertension are disclosed.
|
|
|
6680337 |
Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
The present invention provides cyclopentane heptanoic acid, 2 heteroaryl alkyl or alkenyl derivatives which may be substituted in the 1-position with hydroxyl, alkyloxy, amino and amido groups,...
|
|
|
6673841 |
Alprostadil alkyl ester-containing composition for external application
The present invention relates to a composition of topical preparation containing alprostadil alkyl ester, and more particularly, comprising an alprostadil alkyl ester, an oily vehicle, a skin...
|
|
|
6664290 |
Oral or vaginal administration of mesoprostol in third stage labor
This invention relates to a method of limiting postpartum hemorrhage comprising administering orally a single effective dose of misoprostol to a woman during the third stage of labor.
|
|
|
6649655 |
11β-fluoro 15β-hydroxy PGF2α analogs as FP receptor antagonists
Methods and compositions for the antagonism of FP receptor-mediated biological responses are disclosed.
|
|
|
6649654 |
Methods for identifying and using IKK inhibitors
The present invention provides methods and compositions for inhibiting IKK, as well as methods and compositions for identifying compounds with activity as inhibitors of IKK, and methods and...
|
|
|
6646001 |
Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
Disclosed are methods and compositions for the treatment of glaucoma and ocular hypertension, comprising the administration of a prostaglandin FP receptor agonist and a prostaglandin synthesis...
|
|
|
6610719 |
Use of prostaglandin (PGE2) receptor a (EP4) selective agonists for the treatment of acute and chronic renal failure
This invention is directed to methods and compositions of treating acute or chronic renal failure or dysfunction, or conditions caused thereby, comprising administering prostaglandin agonists,...
|
|
|
6610715 |
Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same
The present invention provides novel cathecol hydrazone derivatives of formula (I) or pharmaceutically acceptable salts thereof, wherein R 1 is C 1-7 alkyl or C 3-7 cycloalkyl; R 2 is hydrogen,...
|
|
|
6596765 |
Treatment of ocular hypertension and glaucoma
15-keto latanoprost and other 15-keto prostaglandin analogs are used as ocularly applied intraocular pressure reducing agents.
|
|
|
6596752 |
Inhibitors of α4β1 mediated cell adhesion
The present invention relates to small molecules according to the formula [I]: which are potent inhibitors of α 4 β 1 mediated adhesion to either VCAM or CS-1 and which can be used for...
|
|
|
6589990 |
Methods and compositions for misoprostol compound treatment of erectile dysfunction
Therapeutic formulations and methods for treating erectile dysfunction with a misoprostol compound in a subject are provided, a method comprising: obtaining a therapeutic formulation having an...
|