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5811129 |
Hydroxylated milk glycerides
Hydroxylated milk glycerides having low levels of ethylenic unsaturation are disclosed. The hydroxylated milk glycerides can have enhanced resistance to rancidification and as such, are suitable...
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5792796 |
Methods for treating anxiety and panic
The instant invention is novel uses of known cyclic amino acids. Such compounds as gabapentin are useful in the treatment of anxiety and in the treatment and/or prevention of panic attacks.
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5783600 |
Carboxyalkylethers, formulations, and treatment of vascular diseases
Dialkyl ethers lower Lp(a) and triglycerides, and elevate HDL-cholesterol, and are thereby useful for treating vascular diseases and noninsulin-dependent diabetes mellitus.
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5763483 |
Carbocyclic compounds
Novel carbocyclic compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane...
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5750549 |
Cycloalkyl tachykinin receptor antagonists
The present invention is directed to certain novel compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R 3 , R 6 , R 7 , R 8 , R 11 , R 12...
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5741814 |
Cyclooctadiene derivatives
Cyclooctadiene derivative of the following formula (1): ##STR1## wherein A 1 , A 2 , A 3 and A 4 each independently represent COOR 5 (where R 5 represents a hydrogen atom, a C 1 -C 10 alkyl...
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5741816 |
Hair-growth agent
Disclosed is a hair-growing (restoration) agent which comprises a carnitine compound represented by the formula (I): ##STR1## wherein R 1 to R 3 each represent an alkyl group having 1 to 6 carbon...
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5736571 |
Guerbet meadowfoam esters in personal care
The present invention deals with the application of certain novel esters which are prepared by the reaction of a guerbet alcohol and meadowfoam fatty, methyl ester or triglyceride in personal care...
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5728733 |
N-acyl-ethylene triacetic composition for treating abnormal keratinization
Disclosed is the novel use of N-acyl-N,N',N'-ethylene-diaminetriacetic acids and N-acyl-N,N',N'-(ethylenedioxy) diethylenedinitrilotriacetic acids as active ingredients in preventative as well as...
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5721274 |
Repellents for ants
A method has been discovered for repelling ants by treating objects or areas with effective amounts of compositions that include (a) one or more C 6 to C 8 carboxylic acids; (b) one or more C 6 ...
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5716926 |
Composition of pyruvate and protein and method for increasing protein concentration in a mammal
The present invention is based in part upon the discovery that the use of pyruvate in enteral formulations, in combination with an anabolic protein composition, produces a synergistic effect in...
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5712311 |
Cosmetic or dermatological composition with controlled release of active principle containing a photoconvertible carotenoid
The invention relates to a cosmetic or dermatological composition with controlled release of active principle containing at least photoconvertible carotenoid, capable of being converted to retinol...
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5698592 |
Materials and methods for controlling nematodes
Methods and compositions for the control of nematodes are disclosed. Specifically, fatty acid ester compounds have been found to advantageously control nematodes at concentrations which are...
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5681855 |
PGE.sub.1 emulsion composition kit
The invention concerns a kit for the preparation of an emulsion containing prostaglandin E 1 , a method of preparing the emulsion and a method of preparing the emulsion composition contained in the...
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5681846 |
Extended stability formulations for paclitaxel
The present invention is directed to improved pharmaceutical compositions employing paclitaxel that are formulated to increase stability and solubility. These improved formulations are useful in...
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5665774 |
Immunosuppressive compounds
This invention relates to a novel class of immunosuppressive compounds having an affinity for the FK-506 binding protein (FKBP). Once bound to this protein, the immunosuppressive compounds inhibit...
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5643949 |
Phenyl alpha acyloxyalkanoic acids, derivatives and their therapeutic use
Therapeutic as well as preventative measures to improve the cosmetic conditions or to alleviate the symptoms of dermatologic disorders with phenyl alpha acyloxyalkanoic acids and derivatives is...
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5637612 |
Oral antibacterial compositions and method for the improvement of gastrointestinal absorption of penem or carbapenem antibiotics
Oral antibacterial compositions contain a penem or carbapenem antibiotic in combination with an absorption improver selected from substances capable of inhibiting the dipeptidase localized on/in...
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5622916 |
Substituted 2-cylcohexen-1-yl-amine fungicidal and herbicidal agents
A method of combating pests which comprises applying to such pests or to a pest habitat a pesticidally effective amount of a substituted 2-cyclohexen-1-yl-amine derivative of the formula ##STR1##...
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5616616 |
Room Temperature sterilant
Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two...
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5610186 |
Flea killer method and compositions
A safer, more effective, ectoparasite killer composition consisting essentially of an effective amount of a natural soap, a surfactant, and water.
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5602178 |
Bath products containing menthyl lactate
A method of achieving a relaxing, invigorating, tingling bath in the substantial absence of a menthol aroma, comprising incorporating into said bath a bath product formulation comprising menthyl...
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5589507 |
Method for sterilizing medical devices utilizing a room temperature sterilant
Provided is an anti-microbial composition containing an ester of formic acid, an oxidizer, performic acid and water. Also provided is a premix for making the anti-microbial composition having two...
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5583136 |
Retinoid containing skin care compositions containing imidazoles
Skin care compositions comprising a water-in-oil emulsion base containing retinoids and at least one imidazole in a free base form and possessing good physical and chemical stability.
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5565490 |
P-hydroxyaniline derivatives, their preparation and their use
p-Hydroxyaniline derivatives of the formula I ##STR1## where the substituents have the following meanings: R 1 is hydrogen, or unsubstituted or substituted alkyl; R 2 and R 3 independently of...
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5559149 |
Skin care compositions containing retinoids
Skin care compositions comprising a water-in-oil emulsion base containing retinoids and possessing good physical and chemical stability. The retinoids suitable for use in these skin care...
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5545399 |
Cosmetic composition
A composition for topical application to the skin in order to promote the repair of photo-damaged or aged skin and/or to reduce or prevent damaging effects of ultra-violet light on skin and/or to...
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5536740 |
Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester
Dimethyl imidazolidinone in combination with either retinol or retinyl ester resulted in a synergistic enhancement in keratinocyte proliferation and synergistic inhibition of keratinocyte...
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5519054 |
Pharmaceutical compositions containing N-acetyl-cysteine derivatives useful for the treatment of cataract
Pharmaceutical compositions for the treatment of cataract containing N-acetyl-L-cysteine derivatives of formula ##STR1## (wherein R and R 1 have the meanings reported in the specification) are...
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5502061 |
Peptidyl substituted benzamides and naphthamies
The present invention provides HIV protease inhibitors, pharmaceutical formulations containing those compounds and methods of treating and/or preventing HIV infection and/or AIDS.
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5491170 |
β-carboxy sulfonamide ACAT inhibitors
β-Carboxy sulfonyl compounds of the formula ##STR1## wherein R 1 is aryl, R 3 is hydrogen or alkyl, R 3 and R 4 are hydrogen or alkyl, Y is --O--, --S--, or --NR 2 --, and R 5 is alkyl or...
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5491169 |
Amino acid derivatives and their therapeutical applications
Compounds having the properties of morphinic substances, particularly anasia, with beneficial effects on behaviour and with peripheral effects without their major drawbacks (tolerence, addiction),...
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5472970 |
Allylaminoesters and their application in therapeutics
Allylaminoesters of the formula (I): ##STR1## in which: R 1 is H or low-molecular-weight alkyl, R 2 is low-molecular-weight alkyl, cycloalkyl, or low-molecular-weight phenylcycloalkyl, pyridyl...
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5470877 |
Uses of perillic acid methyl ester
A method of causing carcinoma regression is disclosed. One administers an effective amount of perillic acid methyl ester. The use of perillic acid methyl ester is disclosed. A pharmaceutical...
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5470878 |
Cell signaling inhibitors
Therapeutic compounds have the formula: (X)j-(non-cyclic core moiety), j being an integer from one to three, the core moiety is non-cyclic and X is a racemic mixture, R or S enantiomer, solvate,...
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5462726 |
Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A.sub.2 receptor antagonist and pharmaceutical compositions containing such solvents
A method is provided for inhibiting or preventing toxicity and other unwanted effects (a) caused by solvents for pharmaceuticals which solvents contain castor oil or ricinoleic acid or derivatives...
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5455273 |
N,N-disubstituted arylcycloalkylamines, the salts thereof, pharmaceutical compositions containing these compounds and the use thereof and processes for preparing them
The invention relates to N,N-disubstituted arylcycloalkylamines of general formula ##STR1## wherein n, m, A, X and R 1 to R 7 are defined as in claim 1, the isomers, isomer mixtures and salts...
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5449684 |
Cytotoxic compounds
Compounds isolated from a marine sponge, and derivatives thereof, have the formulae: ##STR1## in which R 1 is H or lower alkyl; R 2 is OH or CH 3 ; R 3 is OH or CH 3 , and R 4 H or MPTA. The...
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5446055 |
Polyether naphthalenic lignan lactones as inhibitors of 5-lipoxygenase
Compounds of formula ##STR1## Ar is optionally substituted phenyl, furyl, pyridyl, or thienyl; Y is selected from hydrogen, halogen, cyano, alkyl, haloalkyl, alkoxy, and alkoxycarbonyl; L is...
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5428073 |
Antimicrobial agents which are substituted 2-cyclohexan-1-yl-amine compounds.
There are described new 2-cyclohexan-1-yl-amine derivatives of formula (I) ##STR1## in which A, R 1 , R 2 , R 3 and R 4 have the meaning given in the description, and processes for their...
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5426111 |
[Alkoxy-, alkenyloxy-, alkynyloxy-, and phenylmethyloxyalkoxycycloalkyl or alkoxycycloheteroalkyl]naphtho[2,3-c]furan-1(3H)-one inhibitors of 5-lipoxygenase
Compounds of formula ##STR1## Ar is selected from (a) phenyl, (b) phenyl substituted with one or more groups selected from halogen, cyano, alkyl, haloalkyl, alkoxy, and alkoxycarbonyl, (c) furyl,...
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RE34878 |
Hypoglycemic agent
A compound of D-phenylalanine derivative for hypoglycemic use, represented by the general formula ##STR1## R 1 is selected from hydrogen, alkyl of 1 to 5 carbon atoms, aryl of 6 to 12 carbon...
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5395853 |
Anti-atherosclerotic diaryl compounds
The present invention is concerned with compounds of formula (I) ##STR1## wherein m is 0 or 1; W is hydrogen, a C 1 -16 straight, branched, or cyclic alkyl group, or a C 2 -16 straight,...
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5395851 |
Tree wound coating composition
A coating composition for application to tree wounds, such as pruning wounds of living trees is provided. The composition is non-phytotoxic and provides extended protection against fungal...
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5393764 |
Cyclic phenolic thioethers
The compounds of the present invention comprise substituted phenolic thioethers represented by the formula ##STR1## wherein: R 1 and R 2 are the same or different and independently represent...
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5314877 |
Water-soluble pentacyclic triterpene composition and method for producing the same
Disclosed is water-soluble composition made by subjecting pentacyclic triterpene compound belonging to amylin group such as oleanolic acid, ursolic acid and hederagenin to inclusion in...
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5308864 |
6-(hydronaphtyl-1-ethyl)-4-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones and the corresponding hydroxy acids
Compounds of either of general formulae (I) and (II), wherein: R 1 represents a C 1 -8 alkyl, C 3 -8 cycloalkyl, C 3 -8 cycloalkyl(C 1 -8)alkyl, C 2 -8 alkenyl, or C 1 -6 alkyl substituted phenyl...
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5296503 |
Medicaments containing substituted 2-cyclohexene derivatives and their use for the control of candida infections
The present invention relates to the use of known substituted 2-cyclohexene derivatives in the control of diseases, in particular bacterial infections and mycoses.
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5272174 |
Hydroxy-ML-236B derivatives, their preparation and use
Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be...
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5264455 |
Sulfur-substituted mevinic acid derivatives
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