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7597825 |
Method of quenching electronic excitation of chromophore-containing organic molecules in photoactive compositions
The photostabilizing electronic excited state energy—particularly singlet state energy from a UV-absorbing molecule has been found to be readily transferred to (accepted by)...
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7588702 |
Method of quenching electronic excitation of chromophore-containing organic molecules in photoactive compositions
The photostabilizing electronic excited state energy—particularly singlet state energy from a UV-absorbing molecule has been found to be readily transferred to (accepted by)...
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7531573 |
Use of triaryl methane compounds for inhibiting unwanted cellular proliferation associated with inflammatory disease
The present invention provides a class of chemical compounds useful as efficacious drugs in the treatment of sickle cell disease and diseases characterized by unwanted or abnormal cell...
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7476650 |
Enzyme inhibition
Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of...
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7470723 |
Diphenylethylene compounds and uses thereof
The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various...
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7468446 |
Substituted heterocyclic compounds and uses thereof
The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or...
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7402704 |
Arylsulfones and uses related thereto
Aryl sulfone compounds of formula I and II are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders:
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7390833 |
Method for treating ADAMTS-5-associated disease
The present invention relates to methods of treating ADAMTS-5-associated diseases and particularly osteoarthritis comprising administering an agent capable of modulating ADMATS-5 activity to a...
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7371747 |
Cyanoalkylamino derivatives as protease inhibitors
The present invention is directed to novel cyanoalkylamino derivatives that are inhibitors of cysteine protease such as cathepsins K, S, B and L, in particular cathepsin K Pharmaceutical...
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7368479 |
Alpha-sulfonylamino-acetonitriles
The invention relates to α-sulfonylamino-acetonitrile derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein Ar 1 , and Ar 2 ...
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7317066 |
Liquid crystal polymers
Liquid crystal polyester derived from phenylene-naphthalene monomers and one or more comonomers display an improved balance of properties, including low melt viscosity, fast cycle time in molding,...
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7235587 |
Diesters containing two crylene or fluorene moieties, sunscreen compositions containing the same, and methods of photostabilizing a sunscreen compositions containing the same
Diesters that include one or more of a crylene and/or a fluorene moiety, and sunscreen compositions including a mixture of a photoactive compound and one or more of a diester that includes one or...
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7196081 |
Compounds with hydroxycarbonyl-halogenoalkyl side chains
The present invention provides a compound consisting of a moiety and a group chemically bonded to said moiety, wherein said moiety contains a compound having low activity following oral...
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7148255 |
Amidoacetonitrile compounds
The invention relates to compounds of formula I
wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 8 , R 8′ , R 9 , W, X, A 1 , A 2 , a, b and c have the significances given in the specification,...
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7109238 |
Calcilytic compounds
Novel calcilytic compounds and methods of using them are provided.
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7109214 |
Substituted cyclopentene compounds
The present invention relates to substituted cyclopentene compounds of the general formula I, to a process for the production thereof, to pharmaceutical preparations containing these compounds and...
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7019030 |
Immunotherapeutic agents
Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor α, nuclear factor κB, and phosphodiesterase and can be used to combat cachexia, endotoxic shock,...
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7012075 |
Cathepsin cysteine protease inhibitors
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for...
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6946426 |
Process to prepare aqueous formulations
Provided is a method of formulating hydrophobic pesticides comprising emulsifying an aqueous phase and a water-immiscible phase to form a formulation; wherein the aqueous phase is comprised of...
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6881248 |
Paint composition
A paint composition containing an insecticide and piperonyl butoxide as a synergist.
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6838484 |
Formulations comprising selective androgen receptor modulators
The present invention relates to pharmaceutical compositions and formulations comprising a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic...
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6762205 |
Phenyl sulfamate derivatives
Phenyl sulfamate derivatives represented by the following formula or salts thereof have a powerful inhibitory effect on steroid sulfatase and are hence useful for the prophylaxis or treatment of...
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6743820 |
Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor
Novel sulfate ester agents and the use of those agents for treating gastroesophageal reflux disease (GERD) are described, exemplary agents being of the formula: wherein X is —OCH 2 — or...
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6734202 |
Fungicidal mixtures
The invention relates to a novel fungicidal composition comprising a fungicidally acceptable carrier and/or surface active agent together with, and synergistically effective amounts of (a) at...
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6730705 |
Alkoximino acetic acid amides
The invention relates to new alkoximinoacetic acid amides, a process for their preparation and their use as agents for combating pests.
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6713509 |
Controlled release formulation for treating COPD
This invention relates to a controlled or sustained release formulation designed to deliver a PDE4 inhibitor for treating an inflammatory disease such as asthma or COPD and the like.
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6713463 |
Methods and compositions for treating and preventing mucositis
A method of reducing or inhibiting mucositis in a patient, which includes administering an inflammatory cytokine inhibitor or a mast cell inhibitor, or a combination thereof, is disclosed.
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6706743 |
β3 adrenergic receptor agonists and uses thereof
The instant invention provides β 3 adrenergic receptor agonists of structural Formula (I), the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds,...
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6699884 |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds...
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6670400 |
Phenoxyethylamine derivatives having high affinity for the 5-HT1A receptor, preparation thereof, use thereof as drugs, and pharmaceutical compositions containing said derivatives
Phenoxyethylamine derivatives of general formula (I) having high affinity for the 5-HT 1A receptor, methods for preparing same, pharmaceutical compositions containing said derivatives, and their...
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6667346 |
Method for protecting cells and tissues from ionizing radiation toxicity with α, β unsaturated aryl sulfones
Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the toxic side effects of ionizing radiation. Administration of a radioprotective α,β unsaturated aryl sulfone...
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6635663 |
Pesticidal emulsifiable concentrate
The present invention provides a low-irritant pesticidal emulsifiable concentrate comprising (a) 1 to 60% by weight of at least one pesticidal active ingredient compound selected from the group...
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6624179 |
Geometrical isomers of acrylonitrile compounds, mixture thereof, and process for producing these
A geometrical isomer of an acrylonitrile compound represented by the formula (I) or of its salt, or a mixture thereof: [wherein T is phenyl or pyridyl, which is substituted by R 2 , Q is phenyl,...
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6582732 |
Synergistic combination of insecticides to protect wood and wood-based products from insect damage
A wood treatment material having a synergistic combination of insecticides including boron-containing compounds and synthetic pyrethroids, is provided. This combination is shown to be especially...
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6555576 |
Method for treating exercise induced asthma
Methods of treating exercise-induced asthma using a PDE-4 inhibitor are disclosed.
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6552066 |
Protein tyrosine kinase inhibitors for treating osteoarthritis
Disclosed is a method of treating an individual or animal with osteoarthritis. The method comprises administering to the individual or animal a therapeutically effective amount of a protein...
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6538029 |
Methods for treatment of renal cell carcinoma
A method of treating renal cell carcinoma in a mammal with that disease comprising administering to the mammal a physiologically effective amount of an inhibitor of PDE10.
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6495604 |
Cycloalkene derivatives, process for producing the same, and use
The present invention provides a compound represented by the formula: wherein R represents an aliphatic hydrocarbon group optionally having substituents, an aromatic hydrocarbon group optionally...
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6472415 |
Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes
Substituted phenylalanines are provided comprising an hydantoin, urea or 2-hydroxyl, 2-methylpropionyl group, dimers thereof and alkyl, polyfluoroamido and haloarylamino derivatives thereof, as...
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6436971 |
Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection
This invention relates to a method for the prophylaxis of or reducing the severity of post-viral bacterial infection by administering a PDE 4-specific inhibitor prior to or during the course of a...
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6436421 |
Pesticide compositions
The present invention relates to pesticide compositions. In particular, the present invention relates to pesticide compositions comprising a pesticide and a redispersible polymer and to a method...
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6409809 |
Pigmented coatings exhibiting reduced fading
A method for preventing the fading of pigmented coatings, especially water based acrylic paints, includes incorporating therein a biocide containing a mixture of from about 1% to about 99% by...
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6395776 |
Pesticides
New pesticidal compositions which comprise at least one signal substance, at least one UV absorber which is only sparingly miscible with water, at least one unsaturated oil which is only sparingly...
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6333354 |
Synergistic combination of PDE inhibitors and adenylate cyclase agonists or guanyl cyclyse agonists
A diseased state based on acute or chronic obstruction of vessels and/or bronchi, acute or chronic inflammation and/or edema formation is advantageously treated by the combined administration of a...
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6319949 |
Pesticidal sprays
A method for preventing fungal diseases in crops which comprises the steps of: (a) applying to a crop an aqueous or a non-aqueous spray composition which includes a pesticide and a spray adjuvant...
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RE37438 |
Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase
A class of acetamidine derivatives of general formula (I) ##STR1## wherein R 1 is hydrogen, C 1 -6 hydrocarbyl group optionally substituted by halo, halo, nitro, cyano or a group XR 3 wherein X...
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6288112 |
Use of pyrethroid compounds to promote hair growth
A method of promoting hair growth which includes administering to a subject an effective amount of a pyrethroid. A composition having a pyrethroid and a pharmaceutically acceptable carrier for...
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6271263 |
Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
Novel derivatives of 1-aminoindan and their salts are described. Optically active 1-aminoindan derivatives are prepared by reacting a N-benzyl analog of the desired compound with an enantiomer of...
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6262091 |
Process and agents for controlling harmful fungi
Compositions for controlling harmful fungi, containing in a solid or liquid carrier a) at least one p-hydroxyaniline derivative of the formula I ##STR1## b) at least one amide compound of the...
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6251833 |
2-arylcyclopentan-1,3-diones
The present invention relates to novel 2-aryl-3-hydroxy-Δ 2 -cyclopentene-1-one derivatives of the formula (I) ##STR1## in which A, B, D 1 , D 2 , G, W, X, Y and Z are each as defined in the...
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