Matches 101 - 150 out of 219 < 1 2 3 4 5 >
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5430057 Parenteral busulfan for treatment of malignant disease  
Stable parenteral formulations of busulfan safe for parenteral administration are disclosed that exhibit improved bioavailability and optimize high dose busulfan therapy against malignant disease.
5422367 Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents  
Diphenylcyclopropyl analogs in which one or more of the phenyl rings includes substituents comprising a hydroxy group, a hydrogen atom, an acetate group or a substituted or unsubstituted alkoxy...
5415855 Cosmetic composition  
Modified ceramides are defined, together with their synthesis and compositions comprising them for topical application to human skin, hair and nails. The modified pseudoceramides have a structure:...
5378731 Medicated shampoo  
A shampoo composition and related process for disinfecting, cleansing, conditioning, and moisturizing hair. The composition involves the use of a fatty acid monoester of a polyhydroxy alcohol, such...
5376655 Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as an active ingredient  
A derivative of p-guanidinobenzoic acid of the general formula (IA): ##STR1## wherein Y represents an oxygen atom or a sulfur atom and (a) when Y is an oxygen atom, (R 1 ) m is selected from the...
5364882 Oxysulfonyl urea ACAT inhibitors  
Compounds of the formula ##STR1## wherein R is hydrogen, a straight or branched alkyl group having from 1 to 8 carbon atoms or benzyl; wherein each of R 1 and R 2 is hydrogen, an aralkyl group, a...
5330769 Acid sanitizer  
Fatty acid sanitizer concentrates and diluted final solutions are provided which include individual amounts of germicidally effective fatty acid, hydrotrope, strong acid sufficient to lower the pH...
5321045 Method and composition for the treatment of imflammatory conditions using thiosulphinic acid derivatives  
The invention concerns thiosulphinic acid derivatives, medicaments containing these compounds and their use in medicine. It has been found that thiosulphinic acid derivatives display outstanding...
5290810 Compound, use and preparation  
A compound of the formula ##STR1## in which R 1 and R 2 taken together represent a polymethylene chain having 3 or 4 carbon atoms, or a polymethylene chain having 3 or 4 carbon atoms substituted...
5268385 Method for treating schizophrenia  
This invention provides a method for treating the symptoms of schizophrenia by interacting selectively with presynaptic dopaminergic D 2 receptors without appreciably activating postsynaptic...
5232920 N-(mercaptoalkyl)amides  
Novel N-(mercaptoalkyl)amides of the formula ##STR1## wherein R 1 is lower alkyl, cyclolower alkyl, aryl or heteroaryl; R 2 is (COR 3 )-aryl, heteroaryl, substituted (COR 3 )-aryl or...
5194446 Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals  
Methods of treating chronic arthritis and osteoporosis which utilize both known and novel compounds which would fall under the general formula: (HO)p--A--[--OS(O) 2 NR 1 R 2 ] z wherein A...
5192785 Sulfamates as antiglaucoma agents  
Sulfamate esters of the formula (HO) p --A--[OSO 2 NR 1 R 2 ] z where A is aryloxyalkyl, p is the number of unreacted hydroxy groups present on the alkyl moiety and may be zero, z is the...
5151266 Use of anionic detergents with conjugates of monoclonal or polyclonal antibodies  
Methods are disclosed for increasing the solubility of antibodies and their radioisotope, toxin, or drug immunoconjugates and for reducing the non-specific uptake of antibody, either conjugated or...
5140044 UCN-1028D derivatives  
A UCN-1028D derivative represented by the formula: ##STR1## has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.
5124348 Pesticidal amides  
A compound of Formula (I): R 1 (CACA 1 ) x --C(X)NR 2 R 3 (I) where R 1 is alkyl optionally substituted by a group selected from alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, aryl,...
5066675 Substituted phenyl acid esters, their preparation and their use as insecticides and acaricides  
There are described new phenylacetic acid derivatives of general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 , R 5 and R 6 have the meanings given in the description, processes for their...
5063246 Phenethylamine derivative compositions and use  
Phenethylamine derivatives shown by the general formula ##STR1## wherein Ro represents a lower alkyl group; R 1 represents a lower alkyl group or a lower alkoxy group, R 2 represents hydrogen...
5030655 Novel cyclopropane carboxylates  
A compound selected from the group consisting of all possible isomeric forms and mixtures thereof of a compound of the formula ##STR1## wherein R 1 is selected from the group consisting of...
5025031 Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants  
Herein disclosed is a method of treating convulsions with a pharmaceutical composition containing a compound of the formula: (HO) p --A--[OSO 2 NR 1 R 2 ] z where A is an aryl, arylalkyl, or...
5015644 Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds  
Certain substituted urea, thiourea, carbamate, and thiocarbamate compounds are potent inhibitors of the enzyme acyl-CoA: cholesterol acyltransferase and are thus useful agents for inhibiting the...
5010103 Compositions and methods comprising 2-mercaptomethylglutaric acid derivatives  
New compounds having utility for enhancing the activity of antifolates are disclosed of the formula: ##STR1## wherein X is selected from hydrogen ##STR2## and R" ; R' is selected from alkyl,...
4987141 Insecticidal compounds and compositions  
The invention provides insecticidally active compounds of formula: ##STR1## wherein X is N or CH; R a is the group (R 1 )(R 2 )NS(O) n --wherein R 1 and R 2 are independently selected from H,...
4980373 Hydrazone compound and production therefor, and an insecticidal composition containing the same  
A compound of the formula: ##STR1## which is useful as an insecticide.
4975464 Treatment of diseases caused by abnormal action of elastase  
Compounds presented by the general formula: ##STR1## wherein Y is oxygen, R 2 is H, alkyl, alkoxy, alkoxymethyl, --COOR 3 , --CH 2 COOR 3 , --CHCH--COOR 3 , halogen, --CF 3 , --COR 4 , --OCOR...
4945110 Membrame-forming veterinary antibacterial teat dip  
A veterinary antibacterial composition is described which is viscosity stabilized, aqueous, topically adherent and forms a relatively tough, self-supporting film that adheres to the animal until...
4933367 Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds  
This invention relates to carboxylic acid derivatives and their use thereof. The compounds are useful in treatment of various diseases such as diabetes, prediabetic conditions, adipositas ailments...
4906661 Esters of aryloxypropanolamine derivatives  
Novel compounds of the general formula ##STR1## wherein R 1 is lower alkyl, lower cycloalkyl, lower alkenyl, lower alkynyl, lower alkyl carboxymethyl, aryl carboxymethyl, aryl, or aralkyl; A is a...
4876281 Antifungal agents  
An antifungal agent comprising as an effective component a polysulfide compound represented by formula R 1 --S(O) p --R 2 (A) wherein R 1 is CH 3 --, CH 2 ...
4871756 Leukotriene antagonists  
Compounds having the formula: ##STR1## are antagonists of leukotrienes of C 4 , D 4 , E 4 and the slow reacting substance of anaphylaxis. As such, these compounds will be useful as anti-asthmatic,...
4843094 Derivatives of p-guantidinobenzoic acid and pharmaceutical agents containing them as active ingredient  
Compounds presented by the general formula: ##STR1## [wherein when Y is oxygen, R 2 is H, alkyl, alkoxy, alkoxymethyl, --COOR 3 , --CH 2 COOR 3 , --CHCH--COOR 3 , halogen, --CF 3 , --COR 4 ,...
4837229 5-aminosalicylic acid-O-sulfates of physiologically acceptable bases, process for the preparation thereof and drugs containing same  
5-Aminosalicylic acid O-sulfates of physiologically acceptable bases are new substances which are preparable by esterification of 5-nitrosalicylic acid alkyl esters with carbodiimide and sulfuric...
4829084 Method for treating malignant conditions  
A method for inhibiting the growth of malignant cells in a mammal, said cells being susceptible to the action of a compound of the formula H 2 NSO 2 O(CH 2 ) n OSO 2 NH 2 where n is 6-8,...
4808628 Amide derivatives and their use as fungicides  
An amide derivative of the formula (I): ##STR1## or a tautomeric form thereof, wherein R is a phenyl group substituted in the 4-position by a group of R 1 XCH 2 --, where R 1 is C 1 -C 4 alkyl,...
4792569 Anticonvulsant phenethyl sulfamates  
Sulfamates of the following formula (I) are anticonvulsants and are useful in the treatment of epilepsy: ##STR1## wherein R is one or more substituents such as alkyl, halo, alkoxy, CH 3 or nitro;...
4775693 Method for controlling insects and acarina with the use of cinnamamide compounds  
The present invention relates to novel cinnamamide compounds and a process for the preparation thereof. The compounds of the invention are useful for controlling insects and acarina.
4749719 Method of treating skin pigmentation abnormalities with pantetheine-S-sulfonic acid  
Pantetheine-S-sulfonic acid and/or its salt(s) have(has) an effect of curing and preventing pigmentation in the skin, an effect of improving rough skin and a curative effect to wounds, burns and...
4711905 2,4-dihalogenobenzoyl-(thio)urea insecticides  
A 2,4-dihalogenobenzoyl-(thio)urea of the formula ##STR1## in which X represents sulphur or oxygen, X 1 and X 2 are identical or different and represent fluorine, chlorine, bromine or iodine, ...
4701447 N-((2-nitro)phenyl)-N' (organic acid) guanidine anthelmintics  
This invention relates to organic acid-substituted guanidine compounds. Also disclosed are methods for preparing the compounds, compositions containing them, and methods for their use as...
4698333 Use of substituted malonic acid derivatives as agents for combating pests  
Pesticidally active compounds of the formula ##STR1## in which R 1 is an organic radical, R 2 is hydrogen, trialkylsilyl, a hydrocarbon or acyl radical, and R 3 and R 4 independently are...
H000303 Glycoside-containing agricultural treatment composition  
This invention describes a composition of matter and a method of treating agricultural substrates in which an active ingredient selected from the group consisting of fungicides, bactericides,...
4663364 Biocidal fine powder, its manufacturing method and a suspension for agricultural use containing the above powder  
A biocidal powder having a notably reinforced biological effect contains at least 50 wt % of particles having diameter of 0.5 micron or less. A suspension containing the above powder is prepared by...
4643994 Novel organic trithio oxides and method for the preparation thereof  
This invention relates to novel organic trithio oxides of the formula: R 1 --X --R--X 1 --R 1 wherein R is selected from --CH 2 CHCH--, ##STR1## and (CH 2 ) 3 ; X is selected from ##STR2##...
4604404 Antiviral sulfonated naphthalene formaldehyde condensation polymers  
A method is disclosed for combating Herpes simplex viruses, Types I and II, which comprises topically applying and antiviral arylsulfonic acid polymer to the animal tissue under attack. Bacterial...
4598077 Amidine derivatives and cardiotonic compositions  
Amidine derivatives of the formula ##STR1## wherein R 1 and R 2 , which may be the same or different, represent each a hydrogen atom or a lower alkyl group, or R 1 and R 2 together with an...
4556649 Substituted malonic acid diamide insecticides, compositions and use  
Insecticidally active novel substituted malonic acid diamide insecticides of the formula ##STR1## wherein R 1 represents aryl or heteroaryl, each of which can optionally be substituted, R 2 ...
4555522 Antithrombotic and/or antihypertensive compositions  
Hypertension and thrombotic conditions in mammals are treated by administration of sulphite, bisulphite or cyclic sulphite ester of a monohydric or polyhydric alcohol.
4547364 Hair treatment product  
A composition for use in removing chlorine from hair and a method for using the subject composition to remove chlorine from hair are provided. The subject composition preferably comprises ammonium...
4522825 Acaricide compositions employing synergistic mixtures of 1-decyloxy-4-(7-oxa-4-octinyl)-oxy-benzene and propargite  
There are described mixtures with a synergistic action of two acaricide compounds as well as their use in suitable compositions in the fight against mite infestations on useful plants.
4513006 Anticonvulsant sulfamate derivatives  
Sulfamates of the following formula (I): ##STR1## wherein X is O or CH 2 and R 1 , R 2 , R 3 , R 4 and R 5 are as herein defined have been found to exhibit anticonvulsant activity and are thus...
Matches 101 - 150 out of 219 < 1 2 3 4 5 >