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7563434 |
Consumer product comprising a natural preservative system and a method for making the same
Consumer products comprising a natural preservative system are described. The preservative system has a mixture of aliphatic and aromatic isothiocyanates and is suitable for use in a variety of...
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7465442 |
Reduction of dermal scarring
Methods and compositions for reducing or inhibiting dermal scarring by expressing p21 WAF1/Cip1 in a wound site are provided.
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7459483 |
Method and device for detecting fumigants in air samples
The present invention relates to a method and a device for detecting fumigants in air samples. The device can be designed for example as a portable analyzer 10 equipped with a stab probe 11 for...
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7452899 |
Gamma-secretase inhibitors
Compounds of Formula (I): inhibit the processing of APP by gamma-secretase, and hence are useful for treatment or prevention of Alzheimer's disease.
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7449488 |
Pyrazolopyrimidines as protein kinase inhibitors
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of protein and/or checkpoint kinases, methods of preparing such compounds,...
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7432392 |
Ester derivatives and medical use thereof
A therapeutic agent for hyperlipidemia which has no side effects on the liver unlike conventional MTP inhibitors and has excellent MTP inhibitory activity. Also, provided is an ester compound...
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7407986 |
Prevention and treatment of oxidative stress disorders by glutathione and phase II detoxification enzymes
The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels...
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7402569 |
Treatment of Helicobacter with isothiocyanates
The present invention relates to methods of preventing or inhibiting the growth of Helicobacter through the use of a composition that comprises a glucosinolate, an isothiocyanate or a derivative...
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7151118 |
Biphenylcarboxylic amide derivatives as p38-kinase inhibitors
Compounds of formula (I):
or pharmaceutically acceptable salts or solvates thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.
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7150878 |
Extended duration insect repellent composition and method of application to the skin
Disclosed is an insect repellent composition. The composition has an amount of an insect repellent active effective to repel insects when the composition is applied to the skin, and an amount of a...
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7087553 |
Soil fumigant, herbicide, larvacide, ovacide and fungicide
A treatment for eliminating unwanted organisms in agriculture, the treatment comprising a first component comprising allyl isothiocyanate emulsified in water, and a second component comprising a...
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7067554 |
Method for the synthesis of compounds of formula I and their uses thereof
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the...
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6906051 |
Lactone integrin antagonists
The present invention relates to a class of compounds represented by the Formula I:
or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the...
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6867232 |
Gel-like resin molded article contained in volatilization control container
A gel-like resin molded article contained in a volatilization control container is provided. A gelled drug containing allyl isothiocyanate and a resin base is contained in a container, and the...
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6866869 |
Liquid antimicrobial compositions
A liquid antimicrobial composition comprises:
(1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase.
...
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6861442 |
PYK2 and inflammation
The present invention relates generally to the fields of immunology and medicine, and more specifically to the field of cellular signal transduction. The present invention relates, inter alia, to...
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6812248 |
Prevention and treatment of degenerative diseases by glutathione and phase II detoxification enzymes
The present invention generally relates to the field of treating degenerative disease by administering a pharmaceutically effective amount of a compound that elevates glutathione or at least one...
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6710086 |
Protected forms of pharmacologically active agents and uses therefor
In accordance with the present invention, there are provided conjugates of dithiocarbamates “DC”) and pharmacologically active agents (e.g., NSAIDs). Invention conjugates provide a new class of...
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6613801 |
Method for the synthesis of compounds of formula I and their uses thereof
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, their use in treating human or animal disorders. The compounds of the...
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6586407 |
Injectable pharmaceutical formulations for partricin derivatives
New injectable pharmaceutical formulations are described, containing a partricin derivative in the form of a free base as the active ingredient, or a pharmaceutically acceptable water-soluble salt...
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6566403 |
N-acetonylbenzamide fungicides
This invention relates to new compositions comprising predominantly one enantiomer of an N-acetonylbenzamide fungicide, methods of preparing N-acetonylbenzamides, and their use as fungicides.
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6545043 |
Compounds related to natural sources and their use as biopesticides
A method for suppressing target pests, comprising exposing the pests to an effective biopesticidal amount of a composition, the composition comprising a carrier and a purified glucosinolate...
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6465512 |
Leukemic cell growth inhibiting method
Disclosed is a method for growth inhibition of human leukemic cells or therapeutic treatment method of a leukemic patient by using a medicament of which the effective ingredient is a...
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6455518 |
Pharmaceutical compositions for the treatment of transplant rejection, autoimmune or inflammatory conditions comprising cyclosporin a and 40-O-(2-hydroxyethyl)-rapamycin
A synergistic combination of an IL-2 transcription inhibitor (e.g., cyclosporin A or FK506) and 40-O-(2-hydroxyethyl)-rapamycin is provided, which is useful in the treatment and prevention of...
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6447811 |
Pesticide against plant-pathogenic microorganisms
A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic...
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6433011 |
Method for inhibiting formation of aberrant crypt foci in the colon of a mammal
A method is provided for inhibiting the development of colon tumorigenesis in a mammal by administering to the mammal a pharmacologically effective amount of an isothiocyanate selected from the...
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6410265 |
Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina
This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina . The putative efflux gene is useful for probing an organism's efflux system to gain an...
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6407135 |
Conjugates of dithiocarbamates with pharmacologically active agents and uses therefor
In accordance with the present invention, there are provided conjugates of nitric oxide scavengers (e.g., dithiocarbamates, or “DC”) and pharmacologically active agents (e.g., NSAIDs)....
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6407100 |
Fungicidal aromatic oximes
The invention relates to novel compounds of the formula in which R 1 is C 1-4 alkyl and (Y—X) is CH 2 , C 1-2 alkylthio-CH═ or C 1-2 alkyl-ON═ and Z is an aldimino or ketimino group, and...
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6380236 |
Method of treating onychomycosis
A method of treating onychomycosis is described which includes administration to an infected area around a nail of a patient a tissue softening composition containing urea and an antifungal...
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6210881 |
Method for reducing inhibitors of nucleic acid hybridization
The present invention relates to a method for reducing the amount of substances inhibitory to nucleic acid hybridization in samples. The method is practiced prior to release of target nucleic acid...
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6207705 |
Biopesticides related to natural sources
The present invention provides novel biopesticides which can replace commercial pesticides and biopesticides which have been banned, restricted, or are being phased out, including, but not limited...
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6172117 |
Biocidal preservatives
Biocidal preservatives for use especially in preventing rotting and deterioration of wood include quaternary ammonium compounds which preferably have a fatty aliphatic substituent on the quaternary...
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6140362 |
Method for inhibiting the growth of mammalian cells
A method for inhibiting mammalian cell growth is disclosed. The method uses compounds known as N-acetonylarylamides. The compounds have been shown to inhibit cell mitosis and to inhibit microtubule...
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6124352 |
Antifungal agents
A method of treating fungal diseases as well as pharmaceutical, veterinary and agricultural compositions useful in such treatment. The method includes administering an effective antifungal amount...
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6114323 |
Methods for inhibiting the advanced glycosylation of proteins
The present invention relates to methods for inhibiting protein aging. Accordingly, methods are disclosed for treating an animal to inhibit the formation of advanced glycosylation end products of...
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6107316 |
Method for treating protozoal infections
A method for treating protozoal infections is described. The method employs N-acetonylbenzamide compounds provided in an effective amount to inhibit the growth of protozoans. The compounds are...
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RE36784 |
Chemoprotective isothiocyanates
Sulforaphane has been isolated and identified as a major and very potent phase II enzyme inducer in broccoli (Brassica oleracea italica). Sulforaphane is a monofunctional inducer, inducing phase II...
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6077866 |
Benzophenone hydrazone derivatives as insecticides
Novel benzophenonehydrazone derivatives represented by the formula (I): ##STR1## wherein, R 1 is halogen; R 2 is hydrogen or C 1 -4 alkyl; R 3 is cyano, optically substituted C 1 -4 alkyl, C 2...
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6069156 |
Indole derivatives as cGMP-PDE inhibitors
Compounds of the formula (I): ##STR1## and their pharmaceutically acceptable compositions are useful in inhibiting the activity of cyclic guanosine 3',5'-monophosphate phosphodiesterase.
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6022881 |
Insecticidal composition
The presence of isobornyl thiocyanoethyl ether exerts a synergistic effect on the insecticidal activity against harmful wood eating insects of certain known insecticides selected from the group...
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5985303 |
Shelf-life extender for food use
The invention provides a shelf-life extender for upholding the freshness of food, such as meat, vegetables, fruits, etc., in retail packages or in a refrigerator for an extended period of time. An...
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5977123 |
Oximether and acrylic acid derivatives and their use as fungicides
The invention relates to novel oximether and acrylic acid derivatives of the formula (I) ##STR1## in which Z, G, Ar, E, R 1 and R 2 have the meanings as given in the specification, to processes...
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5968498 |
Freshness retaining gel composition
The freshness of meat, vegetables and fruits in a refrigerator or food storage box can be retained for a long period of time by using (1) a freshness retaining gel composition which comprises a...
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5932614 |
Sulfonic stilbene compounds in the treatment of viral diseases
Sulfonic acid stilbenes block the infection of cells by HIV and these compounds can be used to prevent viral infection.
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5880150 |
Antimicrobial agent containing allyl isothiocyanate and method for controlling release speed of allyl isothiocyanate
An antimicrobial agent comprising allyl isothiocyanate (AIT) packaged in a packaging material having a structure wherein part of the pores of a porous packaging substrate is filled with, or said...
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5869067 |
Bi-aromatic compounds and pharmaceutical and cosmetic compositions
The present invention relates to new aromatic compounds, to their preparation and to their use in human and veterinary medicine and in cosmetic compositions.
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5858402 |
Methods for in vivo reduction of cyanide levels and compositions useful therefor
In accordance with the present invention, there are provided in vivo methods for the reduction of cyanide levels. The present invention employs a scavenging approach whereby cyanide is bound in...
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5756542 |
Ointment-like preparation comprising allyl isothiocyanate for the protection of a tree and method of protecting a tree
A method of protecting a tree including removing parts of the tree which are one of susceptible to necrosis from pathogenic microbes or affected by necrosis and leaving exposed tree surfaces; and...
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5728730 |
Synergistic antimicrobial compositions containing methylene-bis(thiocyanate) and an organic acid
Compositions for controlling the growth of microorganisms in or on a product, material or medium comprising synergistically effective amounts of methylene-bis(thiocyanate) and at least one organic...
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