Matches 1 - 50 out of 193 1 2 3 4 >
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7368478 Methods for inhibiting angiogenesis and tumor growth  
Angiogenesis, tumor growth, and metalloproteinase 2 (MMP2) interaction with integrin-α v β 3 are inhibited by an inhibitor compound of formula: wherein G 1 and G 2 are each independently...
7235585 Enzyme activated self-immolative n-substituted nitrogen mustard prodrugs  
This invention pertains to certain enzyme (CPG2) activated self-immolative nitrogen mustard prodrugs, which are useful in enzyme prodrug therapy (EPT), such as ADEPT and GDEPT, for the treatment of...
7122576 Carbamate compounds for use in preventing or treating bipolar disorder  
This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of...
7115660 Methods for inhibiting angiogenesis and tumor growth  
Angiogenesis, tumor growth, and metalloproteinase 2 (MMP2) interaction with integrin-α v β 3 are inhibited by an inhibitor compound of formula (I): wherein G 1 and G 2 are each independently...
7087643 Carbamate compounds for use in preventing or treating neuropathic pain and cluster and migraine headache-associated pain  
This invention is directed to a method for preventing or treating neuropathic pain and cluster and migraine headache-associated pain comprising administering to a subject in need thereof a...
7078436 Carbamate compounds for use in preventing or treating anxiety disorders  
This invention is directed to a method for preventing or treating anxiety disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected...
7056919 Synergistic combination of fungicides to protect wood and wood-based products and wood treated by such combination as well as methods of making the same  
A wood treatment composition having a synergistic combination of fungicides which may include two or more compounds. These combinations are shown to be especially effective in providing resistance...
RE38915 Nonpeptide insulin receptor agonists  
Modulation of the activity of the insulin receptor, enhancement of glucose uptake by cells, and other effects significant in the control and management of diabetes are accomplished using compounds...
6960571 Methods and compositions for administration of iron for the treatment of restless leg syndrome  
A method of treating Restless Leg Syndrome, includes administering to a subject an iron complex having an iron release rate greater than IDI. The iron release rate is determined at a concentration...
6838482 Fungicidal composition  
The present invention provides a fungicidal composition characterized by containing as active ingredients (a) a compound represented by the formula I: (wherein Ar is a substituted or...
6815464 Carbamate compounds for use in the treatment of pain  
This invention is directed to a method for the treatment of pain comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected from the group...
6790853 Contraception method using competitive progesterone antagonists and novel compounds useful therein  
Competitive progesterone antagonists, including two novel steroids, viz., 11β,19-[4-(cyanophenyl)-o-phenylene]-17β-hydroxy-17α-(3-h ydroxyprop-1(Z)-enyl)-4-androsten-3-one and...
6649591 Polydithicarbamate-containing non-targeting marcomolecules and the use thereof for therapeutic and diagnostic applications  
In accordance with the present invention, there is provided a new class of drugs for therapeutic treatment of such indications as cerebral stroke and other ischemia/reperfusion injury. Thus, in...
6608074 Contraception method using competitive progesterone antagonists and novel compounds useful therein  
Competitive progesterone antagonists, including two novel steroids, viz., 11β,19-[4-(cyanophenyl)-o-phenylene]-17β-hydroxy-17α-(3-h ydroxyprop-1(Z)-enyl)-4-androsten-3-one and...
6599935 Felbamate derived compounds  
The present invention relates to novel felbamate derivatives and their use to treat neurological diseases such as epilepsy and to treat tissue damage resulting form ischemic events. The felbamate...
6589985 Carbamate compounds for use in preventing or treating movement disorders  
This invention is directed to a method for preventing or treating movement disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected...
6586466 Carbohydrazide-protease inhibitors  
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or...
6548540 Method of treating cancer using dithiocarbamate derivatives  
Dithiocarbamate, particularly tetraethylthiuram disulfide, and thiocarbamate anions strongly inhibit the growth of cancer cells of a variety of cell types. Such inhibitory effect is enhanced by...
6545027 Methods of modulating NF-kB transcription factor  
A method of modulating NF-kB transcription factor comprising administering to a human in need thereof an effective amount of a compound having the formula wherein R 1 and R 3 are independently...
6541513 Carbamate compounds for use in preventing or treating psychotic disorders  
This invention is directed to a method for preventing or treating psychotic disorders comprising administering to a subject in need thereof a therapeutically effective amount of a compound selected...
6538024 Felbamate derived compounds  
The present invention relates to novel felbamate derivatives and their use to treat neurological diseases such as epilepsy and to treat tissue damage resulting form ischemic events. The felbamate...
6515019 Methods of providing symptomatic and prophylactic treatment for medical and neurological conditions  
Methods are disclosed for prophylactically and chronically preventing symptomatic depression, neuronal cell injury and cell death in systemic and neurological conditions, populations with...
6436421 Pesticide compositions  
The present invention relates to pesticide compositions. In particular, the present invention relates to pesticide compositions comprising a pesticide and a redispersible polymer and to a method...
6416789 Synergistic combination of fungicides to protect wood and wood-based products from fungal decay, mold and mildew damage  
A wood treatment material having a synergistic combination of fungicides including boron-containing compounds, organo-iodine compounds and amine-oxides is provided. This combination is shown to be...
6331542 Protease inhibitors  
The present invention provides compounds which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or...
6319949 Pesticidal sprays  
A method for preventing fungal diseases in crops which comprises the steps of: (a) applying to a crop an aqueous or a non-aqueous spray composition which includes a pesticide and a spray adjuvant...
6315991 Urethane surfactants and their use in personal care formulations  
The present invention is directed to monomeric and polymeric compositions based upon polymeric urethane surfactants which are derived from linear, branched, or aromatic compounds of synthetic or...
6290992 Foam formulation for termite control and method of application therefor  
A method of termite control consists of injecting a foam formulation above ground into the walls of a structure infested with termites or other undesirable pests. The inner spaces of affected walls...
6288110 Pharmaceutical compositions comprising disulfiram  
Disulfiram (tetraethylthiuram disulfide) is shown to inhibit angiogenesis and to be useful in the treatment of angiogenesis-dependent disorders, including neoplasms, and to prevent cell...
6225345 Azahexane derivatives as substrate isosters of retroviral asparate proteases  
The invention relates to compounds of formula (I): ##STR1## wherein R 1 and R 10 are each independently of the other lower alkoxycarbonyl; either R 2 , R 3 and R 4 are each independently of the...
6221896 Insecticidal and miticidal compositions  
6177067 Hair revitalizing tonic composition containing a 2,2-dimethylpropanediol compound and use thereof  
Disclosed is a hair revitalizing tonic composition containing a dimethylpropanediol derivative of the formula: ##STR1## wherein R 1 and R 2 are each independently a C 1 -30 hydrocarbon group...
6130209 Lock and key micelles  
A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a...
6127412 Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol  
The optically pure forms of monocarbamates of halogenated 2-phenyl-1,2-ethanediol and dicarbamates of 2-phenyl-1,2-ethanediol have been found to be effective in the treatment of disorders of the...
6103768 Fatty acid based compositions and methods for the control of plant infections and pests  
The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination...
6066656 2,5-diamino-3,4-disubstituted-1,6-diphenylhexane isosteres comprising benzamide, sulfonamide and anthranilamide subunits and methods of using same  
The present invention provides 2,5-diamino-3,4-disubstituted-1,6-diphenylhexane (DAD) isosteres comprising benzamide, sulfonamide and anthranilamide subunits, a pharmaceutical composition...
6034123 Method for altering blood lipid levels  
Use of bambuterol or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical preparation with lipid lowering effect.
6034117 Methods of treating and diagnosing sleep disordered breathing and means for carrying out the method  
This invention relates to a method for treating snoring, sleep apnea and other form of sleep-disordered breathing, which comprises administration of a therapeutically effective dose of an acetyl...
6005002 Nitrogen mustard prodrugs with novel lipophilic protecting groups, and processes for their production  
The invention provides compounds of formula (I) and (II) wherein X and Y are independently chlorine, bromine, iodine, a mesyl group CH 3 SO 3 or a tosyl group OSO 2 phenyl (wherein phenyl is...
5973000 Hair revitalization tonic composition containing a lipid derivative and use thereof  
The invention relates to a hair revitalizing tonic composition containing, as an active ingredient, at least one lipid derivative of the general formula ##STR1## wherein R 1 , R 2 , R 3 , R 4 and...
5942540 Methods of providing symptomatic and prophylactic neuroprotection  
Methods are disclosed for prophylactically and chronically preventing symptomatic depression, neuronal cell injury and cell death in systemic and neurological conditions, populations with...
5854283 Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol  
The optically pure forms of monoocarbamates of halogenated 2-phenyl-1,2-ethanediol and dicarbamates of 2-phenly-1,2-ethaniediol have been found to be effective in the treatment of disorders of the...
5851988 Nonpeptide insulin receptor agonists  
Modulation of the activity of the insulin receptor, enhancement of glucose uptake by cells, and other effects significant in the control and management of diabetes are accomplished using compounds...
5837727 Method for altering blood lipid levels  
Use of bambuterol or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical preparation with lipid lowering effect.
5773469 Diaryl antimicrobial agents  
The invention relates to diaryl antimicrobial compounds of the general formula: ##STR1## where G, E L, J, q, m, X, Ar, W, p, n and A are as described herein, pharmaceutical compositions containing...
5763364 Thixotropic aqueous plant protection agent suspensions  
The invention relates to thixotropic aqueous suspension concentrates of plant protection agents. The invention furthermore relates to the use of these agents in plant protection and the use of...
5728728 Methods of providing neuroprotection  
Novel methods are disclosed for treating acute and chronic neurological disease and attenuating further neuronal cell death in neurological diseases, employing a glycine site antagonist at the NMDA...
5716968 Protein kinase C modulators. H.  
Compositions having anti-inflammatory, antiviral and other activities are disclosed. The compositions are derived from phorboids of the diaminobenzyl alcohol- and diacylglycerol-classes.
5709890 Polyaspartic acid and its analogues in combination with insecticides  
An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small...
5698588 Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol  
The pure enantiomeric forms, as well as enantiomeric mixtures excluding the racemic mixture of monocarbamates of 2-phenyl-1,2-ethanediol substituted with more than one halogen atom on the phenyl...
Matches 1 - 50 out of 193 1 2 3 4 >