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5733924 |
DC 107 derivatives and treatment methods
DC107 derivatives represented by the formula (I): ##STR1## or pharmacologically acceptable slats thereof, wherein R 1 is hydrogen, lower alkoxyalkyl, aralkyloxyalkyl, lower alkoxyalkoxyalkyl,...
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5733935 |
Hydroxylamine derivatives and fungicides containing the same
A hydroxylamine derivatives of formula (I): ##STR1## wherein R represents ##STR2## in which R 1 and R 2 represents alkyl group, alkenyl group, alkynyl group, cycloalkyl group, haloalkyl group,...
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5728729 |
3-methoxy-2-phenylacrylic acid esters used as pest-control agents, especially as fungicides
3-Methoxy-2-phenyl-acrylic esters of the formula ##STR1## in which R represents optionally substituted alkyl, cycloalkyl or aryl and n represents a number 0 or 1, a process for their preparation...
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5723490 |
THF-containing sulfonamide inhibitors of aspartyl protease
The present invention relates to a class of THF-containing sulfonamides which are aspartyl protease inhibitors. This invention also relates to pharmaceutical compositions comprising these...
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5714518 |
HIV protease inhibitors and methods of making the same
HIV protease inhibitors, obtainable by chemical synthesis, block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well...
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5709890 |
Polyaspartic acid and its analogues in combination with insecticides
An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small...
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5658945 |
Urethanes and ureas that induce cytokine production
The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or...
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5658944 |
Anti-atherosclerotic aryl compounds
The present invention is concerned with compounds of formula (I) ##STR1## wherein Ar is a mono- or bicyclic aromatic group optionally containing one or two heteroatoms independently selected from...
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5656660 |
Compositions and methods for treating mast-cell mediated conditions
The present invention describes compounds, methods and compositions effective to treat mast cell mediated inflammatory conditions, such as conjunctivitis, asthma and allergic rhinitis. The...
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5648085 |
Reducing pesticide resistance
Pest populations that have developed pesticide resistance can be treated and killed with an inhibitor for ATP-dependent 150-180 kDa membrane P-glycoprotein as a pretreatment or simultaneously with...
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5639768 |
Substituted amidino compounds, their manufacture and methods of treatment
The invention relates to the compounds of formula (I) wherein the C(NH)--NHR 3 group may be in tautomeric or isomeric form, and pharmaceutically acceptable salts thereof, in which: R 1 is...
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5631293 |
Preparation of amino acid-substituted benzoylguanidines as diagnostic agents
Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them Benzoylguanidines of the formula I ##STR1##...
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5631273 |
Synergistic water soluble preservative compositions of biocidal mixtures
A water soluble preservative antimicrobial composition for addition to commercial use products at predetermined use levels to provide synergistic biocidal activity against a wide range of fungi and...
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5629347 |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
Compounds of formula (I), and salts and prodrugs thereof, wherein Q is R 9 CR 10 R 11 or CH 2 R 9 CR 10 R 11 where R 9 is H or OH and R 10 and R 11 are optionally substituted phenyl,...
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5616612 |
Urethanes and ureas that enhance the growth of bone marrow progenitor cells
The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or...
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5602174 |
Treatment
A method of treatment or prophylaxis of angina in mammals, such as humans, which comprises the administration to the sufferer of an effective amount of a compound of formula (I), or a...
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5599836 |
Pharmaceutical products comprising a parasympathomimetic drug having therapeutic properties in the pathology of human sensibility and the motor system in general and method of use
A pharmaceutical product is disclosed which interferes with pathologies of human sensitivity and of the motor system. This product comprises parasympathomimetic drugs, in particular carbachol,...
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5597840 |
Microemulsion formulation for injection into trees
An agrochemical microemulsion composition for injection into trees, and the use of said composition for preventing and treating damage to trees from disease and pests or regulating tree growth. The...
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5492910 |
Retrocarbamate protease inhibitors
The invention discloses compounds of the formula ##STR1## are disclosed as HIV protease inhibitors.
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5492930 |
Method and formulation for treating CNS disorders
A method for treating CNS disorders and/or improving cognitive ability in a mammal utilizing 2-phenyl-1,3-propanediol monocarbamate is disclosed. Also disclosed are formulations and methods for...
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5484587 |
Diabroticine bait
Baits for diabroticine beetles are microspherical particles containing a homogeneous mixture of a toxicant for diabroticine beetles and a feeding stimulant in a binder containing a gelatin and a...
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5482968 |
Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors
The compounds of this invention which have the formula: ##STR1## wherein: R 1 and R 2 are independently hydrogen, C 1 -C 8 alkyl, halogen, C 1 -C 8 alkoxy, or trifluoromethyl; R 3 is --OH or...
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5482965 |
Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers for physiological active agents
A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or...
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5470875 |
Water soluble, antimicrobial compositions of polyhexamethylene biguanide and iodopropynylbutyl carbamate
A water soluble, antimicrobial composition having antifungal activity useful for disinfecting a contact lens comprise (a) polyhexamethylene biguanide and (b) iodopropynylbutyl carbamate, in a...
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5407959 |
(Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
Compounds of structure ##STR1## where W is selected from the group consisting of ##STR2## where Q is oxygen or sulfur, R 7 and R 8 are independently selected from hydrogen and alkyl, or R 7 and...
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5399590 |
Quaternary ammonium salts and pharmaceutical compositions containing them
The invention relates to the field of organic chemistry and more particularly to that of therapeutic chemistry. More particularly it relates to new quaternary ammonium salts of general formula (I):...
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5385926 |
Microbicidal active compound combinations
New synergistic microbicidal active compound combinations, and the use thereof, comprising an azole fungicide, such as hexaconazole, and an iodopropargyl derivative, such as IPBC, if appropriate...
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5356931 |
Use of α-arylacrylic derivatives for controlling pests
Alpha-Arylacrylic acid derivatives of the general formula I ##STR1## where X is ethylene or ethenylene; n is 0 or 1; m is 0, 1, 2, 3 or 4; R 1 is cyano, cyanato, thiocyanato, nitro,...
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5352698 |
Methods of treatment for patients suffering from Riley-Day disease
A pharmaceutical product is disclosed which interferes with pathologies of human sensitivity and of the motor system. This product comprises parasympathomimetic drugs, in particular carbachol ,...
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5328926 |
Synergistic combinations of iodopropargyl compounds with 1,2-benzisothiazolin-3-one in controlling fungal and bacterial growth in aqueous fluids
Synergistic combinations of iodopropargyl compounds and 1,2-benzisothiazolin-3-one for use in controlling the growth of at least one microorganism, such as fungi and bacteria in aqueous fluids,...
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5304567 |
Biocidal combinations containing 4,5-dichloro-2-cyclohexyl-3-isothiazolone and certain commercial biocides
Synergistic microbicidal compositions are disclosed, comprising 4,5-dichloro-2-cyclohexyl-3-isothiazolone and one or more known microbicides for more effective, and broader control of...
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5300520 |
Wood preservative composition
A wood preservative composition which comprises a wood preservative in an amount of 0.01-10% by weight and a diphenylalkane compound represented by the general formula ##STR1## wherein R 1 , R 2 ,...
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5294430 |
Use of dithiocarbamates to treat myelosuppression
A process for preventing or ameliorating the myelosuppression which can occur in a mammal such as a human cancer patient being treated with a platinum-free antineoplastic drug is provided,...
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5288727 |
Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them
The present invention relates to a hydrazone compound of the formula (I) or its salt, a process for its preparation, an intermediate of the formula (II-5), a pesticidal composition containing said...
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5236950 |
Process for hair growth
This invention relates to a hair-restorer comprising, as an active ingredient, (a) an acyclic branched higher aliphatic hydrocarbon of 20 carbon atoms which may be substituted with hydroxyl group...
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5198470 |
Lipid compounds derived from sphingosines, process for preparing these and their applications, in particular in cosmetics and in the pharmacy of skin conditions
The invention relates to a lipid compound of formula (I): ##STR1## where R 1 denotes a C 11 to C 21 alkyl or alkenyl radical and R 2 denotes a linear or branched C 8 to C 30 hydrocarbon...
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5190944 |
Synergistic microbicidal combinations containing 3-isothiazoline and commercial biocides
The invention relates to synergistic antimicrobial and biocidal compositions comprising 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one and one or more commercial biocides...
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5190932 |
Microbicidal formulations comprising water dispersible polymers with chemically bonded ammonium groups and fatty acid radicals
The invention relates to the use of water-soluble polymers containing chemically bonded tertiary and/or quaternary ammonium groups as auxiliaries for formulating microbicides, the microbicide...
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5180420 |
Water dispersible granules
The water dispersible granule of the present invention contains (a) a pesticidal active ingredient which is solid at room temperature, (b) an anionic surface active agent, and (c) a kaolin series...
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5162343 |
Biocidal compositions and use thereof containing a synergistic mixture of 3-iodo-2-propynyl-butyl carbamate and sodium 2-pyridinethiol-1-oxide
A bactericidal composition and method for inhibiting and controlling the growth of the capsulated, facultative bacterium, Klebsiella pneumoniae, are disclosed. The composition comprises an amount,...
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5153219 |
Thiocarbamate sulfoxide composition for deterring ethanol ingestion
A method is provided for deterring ethanol ingestion by a human, comprising administering to said human an amount of a compound of the formula (R 1 ) R 2 )NC(X)S(O)R 3 effective to cause the...
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5147891 |
Biocidal compositions and use thereof containing a synergistic mixture of 3-iodo-2-propynyl-butyl carbamate and phenyl-(2-cyano-2-chlorovinyl) sulfone
A bactericidal composition and method for inhibiting and controlling the growth of the capsulated, facultative bacterium, Klebsiella pneumoniae, are disclosed. The composition comprises an amount,...
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5141956 |
Pesticidal composition
Ethyl 2-[4-(3-chlorophenoxy)phenoxy]ethylcarbamate is suitable controlling phytophagous cicadas in rice crops and fruit pests such as leaf rollers, citrus fruit pests such as scale insects, and...
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5132312 |
Substituted cyclohexene derivatives as HMG-CoA reductase inhibitors
Disclosed are novel 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors useful as antihypercholesterolemic agents represented by the formula ##STR1## and the corresponding ring-opened hydroxy...
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5118674 |
3-(N-methyl-N-alkyl)-amino 2-methoxymethylene propan 1-ol derivatives, a preparation process of the same and therapeutical compositions containing them
The invention relates to 3-(N-methyl-N-alkyl)-amino 2-methoxymethylene propan 1-ol derivatives of the formula ##STR1## wherein R stands for an alkyl chain, A stands for: ##STR2## and Y represents...
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5100916 |
Carbamic acid ester for treatment of addiction to alcohol
A preparation for treatment of addiction to alcohol, containing a carbamic acid ester having the general formula I ##STR1## wherein X is --CH 3 or --CH 2 CH 3 , R and R 1 which may be the same...
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5091414 |
Pesticidal compounds
A compound of Formula (I): (I) R 1 (CACA 1 ) x --C(X)NR 2 R 3 where R 1 is alkyl optionally substituted by a group selected from alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, aryl,...
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5086060 |
Compound and method for treating skin for acne or psoriasis
The effects of acne and psoriasis are relived by applying either topically or by oral adminstration, a compound having the structure: ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are...
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5084281 |
Method and solution for treating tissue wounds
A method and solution are disclosed for treatment of tissue wounds, particularly ulcerous lesions. The solution comprises a solution of seawater or a sea salt solution to which is added a...
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4983391 |
Fabric insecticide
An insecticide for protecting a fibrous material from the damage by an insect, which comprises a carbamic ester of the formula: ##STR1## wherein R 1 and R 2 are, the same or different, each a...
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