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9029413 Treatment of viral infections by modulation of host cell metabolic pathways  
Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets...
9018251 Method for treating brain cancer or reducing temozolomide-resistance of brain cancer cells  
Provided is a method for treating brain cancer or reducing temozolomide-resistance of brain cancer cells in a subject, comprising administrating to the subject an effective amount of an active...
9012490 Lipophilic curcumin analogs and methods of inhibiting HIV-1, treating latent HIV in the brain, and preventing HIV-mediated cognitive decline and HIV dementia  
Compounds having formulas (I) to (VIII), salts thereof, or combinations thereof and pharmaceutical compositions comprising one or more these compounds are described herein for the treatment of HIV...
8980795 Strigolactone analogues and their use  
Novel compounds of formula (I) their use as germination trap for parasitic weeds, for the regulation of branching, tillering and root development, for enhancement of cambium growth, for the...
8969408 Use of lignan-type compounds or extract of nutmeg or aril of nutmeg comprising the same  
The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition...
8952062 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy  
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to...
8946280 Plant growth regulating compounds  
The present invention relates to novel strigolactam derivatives of formula (I) to processes and intermediates for preparing them, to plant growth regulator compositions comprising them and to...
8946153 Fast dissolving pharmaceutical composition  
The subject invention is directed to a pharmaceutical composition comprising an open matrix network carrying a pharmaceutically active ingredient, wherein the open matrix network comprises levan.
8921417 Method of treating dyslipidemia using naturally occurring diterpene  
A method for treatment and or/prevention of dyslipidemia is provided. The invention relates to reducing low density lipoprotein cholesterol concentration by using naturally occurring diterpene...
8901038 Biphenyl-substituted cyclic ketoenols  
The invention relates to novel compounds of the formula (I) in which W, X, Y, Z, and CKE have the meanings given above, to a plurality of processes and intermediates for their preparation and to...
8859619 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy  
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to...
8841294 Active ingredient combinations having insecticidal and acaricidal properties  
The invention relates to insecticidal and acaricidal mixtures comprising certain cyclic ketoenols and agonists or antagonists of nicotinic acetylcholine receptors for protecting plants against...
8772329 Compounds from mycelium of Antrodia cinnamomea and use thereof  
The present invention relates to compounds from mycelium of Antrodia cinnamomea. The present invention also relates to a composition and a method for treating or prophylaxis of hepatitis C virus...
8734772 Photo-curable resin for cosmetic application  
Disclosed herein are cosmetic compositions comprising (a) at least one styrene-maleic anhydride copolymer bearing at least one group chosen from styrylpyridine and styrylpyridinium groups and (b)...
8716328 Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents  
The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of...
8691855 Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist and pharmaceutical compositions containing the same  
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a...
8658690 Use of novel compounds from fruiting body of Antrodia camphorata for treating an inflammatory disorder  
Disclosed herein are isolated compounds or pharmaceutically acceptable salts thereof, which exhibit immunostimulatory or anti-inflammatory effects. The compounds are isolated from the fruiting...
8653110 Active compound combination comprising azadirachtin and a substituted enaminocarbonyl compound  
Disclosed are novel active compound combinations comprising at least one substituted enaminocarbonyl compound and azadirachtin, which combinations are highly suitable for controlling animal pests...
8648113 Mixture and compounds from mycelia of Antrodia camphorata and use thereof  
The present invention relates to a compound derived from mycelium of Antrodia camphorata. The present invention also relates to the composition or mycelium comprising the compounds of the...
8614211 Certain chemical entities, compositions, and methods  
Chemical entities that are arctigenin derivatives, pharmaceutical compositions and methods of treatment of cancer are described.
8507554 Quorum sensing antagonist and method of reducing a bacterial contamination using the quorum sensing antagonist  
In the quorum sensing antagonist blocking the communication in bacteria, the method for preventing biofilm formation using this quorum sensing antagonist and the method for reducing the bacterial...
8461203 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy  
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gamma-hydroxybutyrate that are also resistant to...
8445533 Andrographolide derivatives to treat viral infections  
The present invention provides a methods and compositions for treating a host afflicted with a viral infection, particularly a Flaviviridae infection, including hepatitis C infection, comprising...
8440714 Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents  
The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of...
8404743 Zinc oxide complexes  
Disclosed are compounds comprising a zinc oxide molecule chemically bound to one or more molecules having an acidic hydrogen, such as an organic acid. The invention also provides compositions...
8394852 Inotilone derivatives as coherent biological response modifier (cBMR)  
Optimal compositions of derivatives of 5-methyl-3(2H)-furanone compounds and phenylpropanoid polyketides related to inotilone, that exert biological response modification in health and disease,...
8367720 Andrographolide derivatives and use thereof in manufacture of medicaments  
The present invention relates to an andrographolide derivative of the formula (I), wherein R1, R2 and R3 are same or different substituents selected from hydrogen, substituted or unsubstituted...
8343465 Cooling cosmetic or dermatological preparations comprising (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)-cyclohexane carboxamide and/or (1R,2S,5R)-N-(4-cyanomethyl-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide for reducing skin reddening  
A topical cosmetic and dermatological preparation for reducing skin reddening which comprises (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl)-cy clohexane carboxamide and/or...
8263650 Microbiologically sound and stable solutions of gamma-hydroxybutyrate salt for the treatment of narcolepsy  
Disclosed are formulations of gamma-hydroxybutyrate in an aqueous medium that are resistant to microbial growth. Also disclosed are formulations of gammahydroxybutyrate that are also resistant to...
8217006 Inhibiting GS-FDH to modulate no bioactivity  
Patients needing NO donor therapy or inhibition of pathologically proliferating cells or increased NO bioactivity are treated with a therapeutically effective amount of an inhibitor of...
8188145 Synthetic lactone formulations and method of use  
Natural and synthetic compounds having a lactone structure methods for alleviation of pain, especially pain associated with disorders such as melanoma, leukemia, breast cancer, lung cancer,...
8183286 EP2 and EP4 agonists as agents for the treatment of influenza a viral infection  
The present invention is directed to the use of EP2 and/or EP4 agonists as therapeutics for the treatment of diseases associated with influenza A viruses, such as for example H5N1 and mutations...
8158677 Treatment of viral infections by modulation of host cell metabolic pathways  
Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets...
8153741 Furanone copolymers  
The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one vinyl group and a second monomer including a furanone possessing...
8148420 Use of novel compounds from fruiting body of Antrodia camphorata for stimulating immune response  
Methods of stimulating immune response or treating an inflammatory disorder with one of a number of the compounds disclosed herein or a pharmaceutically acceptable salt thereof.
8124649 Oxindole compounds  
The invention provides compounds that inhibit PIM kinases and Flt3 kinase, and compositions containing such compounds. These compounds and compositions are useful for treating proliferative...
8084495 Composition of labdane diterpenes extracted from andrographis paniculata, useful for the treatment of autoimmune diseases, and alzheimer disease by activation for PPR-gamma receptors  
The diterpenic labdane 3-[2-[decahydro-6-hydroxy-5-(hydroxymethyl)-5,ha-dimethyl-2- methylene-1-naphthalenyl]ethylidene]-dihydro-4-hydroxy-2(3h) -furanone, chemically diagrammed as inhibits the...
8075908 Apparatus and method for reducing the occurrence of post-surgical adhesions  
A method for inhibiting formation of adhesions following abdominal surgery which involves application of an anti-static fatty acid ethoxylated amide (Cocamide DEA) in a matrix that is placed in...
8058288 Amido compounds and their use as pharmaceuticals  
The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The...
7999051 Furanone copolymers  
The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one vinyl group and a second monomer including a furanone possessing...
7985771 Furanone derivatives  
The invention relates to a method of treating with furanone derivatives and the pharmaceutically acceptable salts thereof, one or more conditions of the skin, in particular regulating skin...
7960437 Skin care composition that mediates cell to cell communication  
There are disclosed skin treatment compositions containing cell signaling compounds, which induce and promote the biosynthesis and/or bioactivity of endogenous chemicals that mediate cell to cell...
7956088 Synthetic lactone formulations and methods of use  
Natural and synthetic compounds having a lactone structure methods for using and making the compounds have been disclosed. The compounds are useful as anti-bacterial, anti-fungal and...
7928037 3-biphenyl-substituted-3-substituted-4-ketolactam and ketolactone and their utilization as pesticide  
The present invention relates to novel 3-biphenyl-substituted, 3-substituted 4-keto-lactams and -lactones of the formula (I) in which A, B, Q, G, W, X, Y and Z are as defined in the disclosure, to...
7923439 Hydroxamate compositions  
The present disclosure provides compositions including a first component including at least one phospholipid possessing at least one vinyl group, a second component including a furanone possessing...
7902255 γ-butyrolactone compound and pharmaceutical composition thereof  
A γ-butyrolactone compound as shown in Formula (I) and pharmaceutical composition thereof: wherein X═N, O, S, Se; and A and B are selected from substituents having the following formula: wherein...
7884130 Gamma-undecenolactone, method for the preparation and use thereof for cosmetics and in the form of food additives  
The invention relates to a gamma-undecenolactone of formula (i), wherein a lactonic cycle can carry an unsaturation between carbon No. 2 and carbon No. 3 and is preferably saturated, RI is a...
7846903 Type II cubic liquid crystal composition  
A cubic liquid crystal composition comprising at least one amphiphilic compound having the following general formula (1) and having an IV/OV value of 0.65 to 0.95, and water or an aqueous medium:...
7816378 Cyclic ketal beta-secretase inhibitors for the treatment of alzheimer's disease  
The present invention is directed to cyclic ketal compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the...
7816389 Organic compounds  
14-O—[(((C1-6)Alkoxy-(C1-6)alkyl)-phenylsulfanyl)-acetyl]-mu tilins, 14-O—[(((C1-6)Mono- or dialkylamino-(C1-6)alkyl)-phenylsulfanyl)-acetyl]-mutilins,...
Matches 1 - 50 out of 435 1 2 3 4 5 6 7 8 9 >