Matches 201 - 250 out of 297 < 1 2 3 4 5 6 >
Match Document Document Title
4784856 Percutaneous pharmaceutical preparation  
A percutaneous administration type pharmaceutical preparation in tape form comprising a flexible backing, which is not permeable by the active ingredient, and an adhesive base layer formed on said...
4778805 4,7-benzofurandione derivatives useful as inhibitors of leukotriene synthesis  
4,7-Benzofurandione derivatives of Formula I, pharmaceutical compositions, and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As...
4769379 Dianhydrohexite derivatives, and their use as pharmaceuticals  
Dianhydrohexites of the formula ##STR1## wherein R 1 is hydrogen or benzyl, R 2 is alkyl or omega-theophyllin-7-yl-alkyl, and R 1 and R 2 together with the nitrogen atom to which they are...
4749714 Nifedipine isosorbide 5-monoitrate combination product  
A solid medicament formulation which can be administered orally comprising 5 to 30 mg of nifedipine and 10 to 40 mg of isosorbide 5-mononitrate. Oral administration of such cardioactive formulation...
4742077 Bicyclic allylether derivatives, processes for their production and their use  
Compounds of formula I ##STR1## wherein R 1 represents a group of formula ##STR2## whereby R 4 and R 5 are the same or different and represent hydrogen, halogen, lower alkyl, lower alkoxy or...
4734280 Treatment or prevention of PAF Acether-induced maladies  
The present invention relates to the treatment of PAF Acether-induced maladies. The treatment comprises the administration of a ginkgolide or a ginkgolide derivative. Ginkgolide B has been found to...
4731385 Insecticidal and fungicidal composition for agricultural and horticultural use  
An insecticidal and fungicidal composition comprising (1) An insecticidally effective amount of a nitromethylene derivative of the formula ##STR1## in which X is a lower alkyl group, a lower alkoxy...
4727086 Certain anti-hypertensive 2,3-dihydrobenzofuran compounds  
The invention relates to 2,3-dihydrobenzofuran derivatives of the general formula: ##STR1## in which: each of X 1 and X 2 , which are identical or different, represents a hydrogen or halogen atom...
4720503 N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors  
N-substituted fused-heterocyclic carboxamide derivatives, for example, N-(2,2-diphenylethenyl)-3-hydroxythieno[3,2-b]thiophene-2-ca rboxamide can be prepared by ring closure between an...
4713393 Phenylpropyl-2,3-dihydrobenzofurans useful as anti-inflammatory agents  
Phenylalkyl-2,3-dihydrobenzofurans and analogs were prepared by (1) nucleophilic substitution involving an appropriately substituted 2,3-dihydrobenzofuranol (or 2,3-dihydrobenzopyranol) and a...
4684661 Anti-fungal homopropargylamines, compositions, and method of use therefor  
The invention relates to novel homopropargylamines of formula I ##STR1## wherein n is 2 or 3, R 1 is a group of formula IIa, IIb or IIc ##STR2## in which R 6 and R 7 independently are H,...
4675320 Aminoalkyl and aminoalkoxy derivatives of 2-nitro-3-phenylbenzofuran  
Antimicrobial 2-nitro-3-phenylbenzofurans wherein the benzo or the 3-phenyl portion of the molecule is bonded to an alkylene or an oxyalkylene group which is in turn bonded to a basic nitrogen atom...
4670457 2H-benzofuran-3-one-derivatives and process for their preparation  
2H-Benzofuran-3-one derivatives, process for their preparation and pharmaceutical compositions containing them. The compounds and compositions are useful in the treatment of allergies.
4666931 Benzofuran derivatives useful in treating diabetic complications  
A benzofuran derivative having the general formula (I): ##STR1## wherein R 1 is hydrogen atom, a benzyl group, unsubstituted or substituted with a halogen atom or an alkyloxy group, or an alkyl...
4659709 2,3-dihydrobenzofuran-5-sulfonamide derivatives useful as antihypertensive diuretic agents  
Highly effective diuretic antihypertensives, i.e., 2,3-dihydrobenzofuran-5-sulfonamide derivatives which is classified to loop diuretics with less adverse side-effects and can be administered...
4656163 Compositions and methods of combating pests employing sulphenic acid amides in combination with known nematicides or insecticides  
The present invention relates to the use of the sulphenic acid amides of the general formula (I) ##STR1## in which X represents identical or different halogen atoms, Y 1 and Y 2 are identical...
4636505 Amide derivatives  
Acylanilides of the formula ##STR1## wherein R 1 and R 2 , the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents; R 3 is hydrogen or...
4634701 Furan derivatives having anti-ulcer activity  
Compounds of formula (I): ##STR1## wherein: A represents a CH-NO 2 group or a N-CN group; B represents CH 2 , O, S or a direct bond; R represents a bicyclic or polycyclic residue, variously...
4632937 Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation  
Dentifrice formulations containing monoalkyl and dialkyl ethers of dianhydrohexitols in the form of toothpaste, mouthwash, chewing gums, confections, toothpicks and dental floss are effective in...
4611008 Preparation of nitroesters for coronary artery therapy  
A gel or gel preparation of improved stability and shelf life having an action on the coronary arteries comprising nitroesters, an oil base and finely disperse silica, wherein the finely disperse...
RE32196 Aurone derivatives  
Substituted aurones of formula (I): ##STR1## wherein R 1 , R 2 R 3 , R 4 , R 5 and R 6 are the same or different and can each represent hydrogen, halogen, C 1 -6 alkyl, C 1 -6 alkoxy, C 3 -8...
4590207 Therapeutic and/or preventive ophthalmic solution for intraocular hypertension and glaucoma  
Therapeutic and/or preventive ophthalmic solution for intraocular hypertension and glaucoma contains isosorbide mononitrate as an active ingredient.
4588713 Selective biologically active 7-oxo-prostacyclin derivatives and pharmaceutical compositions containing same  
Compounds of the formula ##STR1## are disclosed wherein R 1 stands for hydrogen, C 1 -4 straight or branched alkyl or pharmacologically acceptable cation, R 2 stands for hydrogen, C 1 -4...
4588744 Method of forming an aqueous solution of 3-3-Bis(p-hydroxyphenyl)-phthalide  
There is disclosed a method and composition of matter for treating mammalian inflammatory viral infections, acne, dermatitis, and arthritic conditions comprising the application of...
4579865 Benzofuranyl carbamates  
Compounds of the structure; ##STR1## and pharmaceutically acceptable salts thereof, wherein: R 1 is H, alkyl, alkoxy, carboxyl, alkylcarboxy, trifluoromethyl, halogen, nitro or hydroxy; X is...
4552895 Furo[3,2-b]furan-2-(3H)-ones  
The invention provides for certain compounds derived from ascorbic acid and their formulations which are useful in inhibiting angiogenesis in mammals.
4546110 Pheromones  
Compounds which are β-farnesene derivatives obtainable as a Diels-Adler adduct of β-farnesene and a dienophile or by a modification of such an adduct in a manner as defined herein are of value in...
4544667 2-Sulfamoylbenzo[b]furan derivatives for the treatment of elevated intraocular pressure  
Novel 2-sulfamoylbenzo[b]furans and derivatives thereof are shown to be useful for the treatment of elevated intraocular pressure in compositions including opthalmic drops and inserts.
4540709 Method for treatment of diseases mediated by PAF using 5-allyl-2-(3,4-Dimethoxyphenyl)-3a,α-methoxy-3-methyl-2,3,3a,6-tet rahydro-6-oxobenzofuran  
5-allyl-2-(3,4-dimethoxyphenyl)-3a,α-methoxy-3-methyl-2,3,3 a,6-tetrah ydro-6-oxobenzofuran and analogs thereof as PAF-antagonists have been isolated from Piper futokadsura Sieb. et Zucc. and its...
4532257 Certain aurones and their use in the treatment of allergies  
There are described compounds of the formula ##STR1## in which either R 1 and R 2 are both hydrogen or R 1 is carboxyl and R 2 is hydrogen, C 3 -4 alkenyl or C 1 -4 alkyl, and R 3 , R 4 and R...
4529737 Analgesic and anti-inflammatory arylalkanoic acid phthalidyl esters and pharmaceutical compositions thereof  
The present invention concerns novel phthalidyl esters of arylalkanoic acids having improved pharmacological properties in respect to the corresponding arylalkanoic acids having analgesic and...
4520018 5-Substituted-4-oxo-PGI.sub.1 derivatives, PGI.sub.1 compounds of similar structure, their pharmaceutical methods and process for the preparation of said compounds  
New PGI 1 derivatives are disclosed as well as a process for the preparation thereof, pharmaceutical compositions containing same and methods of treatment employing same. The new compounds are...
4518611 2-Furylbutyrolactone modulation of the immune system in mammals  
Compositions containing compounds which exhibit immunomodulatory properties can be used as immunostimulants or immunosuppressants in humans and animals.
4514415 Benzofuran-2(3H)-ones used as anti-inflammatory agents  
The invention relates to novel lactones, especially benzofuranones of the general formula ##STR1## in which R 1 represents hydrogen or an aliphatic radical, R 2 represents an amino group...
4486447 Pesticidal symmetrical bis-sulfenylated-bis carbamate compounds  
Bis-sulfenylated bis-carbamate compounds exhibit activity against insect and mite pests.
4483867 Antifibrinolytically active derivatives of tranexamic acid  
Novel antifibrinolytically active compounds of the formula ##STR1## and therapeutically acceptable salt thereof, wherein R 1 is selected from the group consisting of (a) alkyl groups...
4472429 N-(3-Trimethylstannylpropyl)carbamates and use thereof in pest control  
There are disclosed novel N-(3-trimethylstannylpropyl)carbamates, a process for their preparation and their use in pest control. These carbamates have the formula (CH 3 ) 3 SnCH 2 CH 2 CH 2 ...
4466969 7-Oxoprostacyclin derivatives and their use as hypotensives and bronchodilators  
Prostacyclin, although having a useful dilating effect on blood vessels, is not sufficiently stable to ensure successful use as a hypotensive agent. A 7-oxo prostacyclin derivative of the general...
4459307 Antibacterial drug  
There is disclosed a method for treating and preventing infections caused by bacteria comprising the administration of effective dosage of 3,3-Bis(p-hydroxyphenyl)-phthalide (phenolthalein). The...
4430341 Water soluble pesticidal quaternary ammonium salt compounds  
Water soluble quaternary ammonium salt compounds exhibit outstanding insecticidal and miticidal activity coupled with reduced mammalian toxicity and acceptable phytotoxicity.
4426380 Benzofuran-2-ones and pharmaceutical compositions  
The invention relates to novel furans, especially benzofuranones of the general formula ##STR1## in which R 1 represents hydrogen or an aliphatic radical, R 2 represents an amino group...
4416896 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease  
7-Oxabicycloheptane substituted amino prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4411910 Benzofuran derivatives and their pharmaceutical use  
Benzofuran derivatives of the formula ##STR1## wherein V is hydrogen or acetyl, X is oxo or two hydrogen atoms, R 1 and R 2 each independently is hydrogen, fluorine, or chlorine, and ...
4382953 Ophthalmic solution for intraocular pressure reduction  
An ophthalmic solution suitable for adjusting intraocular pressure comprising (A) an ophthalmologically acceptable, water-soluble salt of 2-acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran,...
4369189 Novel unsymmetrical formamidine-sulfenylated carbamate compounds  
Novel unsymmetrical formamidine-sulfenylated carbamate compounds exhibit broad-spectrum insecticidal, miticidal and nematocidal activity.
4367238 Phenyl-alkanoic acid derivative and preparation thereof  
This invention relates to new phenyl-alkanoic acids, their derivatives at the carboxy group, and pharmaceutically acceptable salts thereof, which have anti-inflammatory, analgesic and antipyretic...
4349565 Cyclobutanedicarboxisoimides and use thereof as fungicides  
The invention relates to cyclobutanedicarboxisoimides of the formula I ##STR1## wherein one of X and Y is oxygen and the other is ##STR2## each of R 1 and R 6 independently is methyl or ethyl,...
4332818 1,4;3,6-Dianhydro-2,5-diazido-2,5-dideoxy-hexitols  
The invention relates to new stereoisomeric 1,4;3,6-dianhydro-2,5-diazido-2,5-dideoxy-hexitols of the Formula I. These compounds can be prepared by (a) reacting a hexitol derivative of the...
4315026 Alkylpolyoxysulfinyl and alkylpolythiosulfinyl derivatives of carbamate esters  
A novel class of chemical compounds useful as pesticides consists of alkylpolyoxysulfinyl and alkylpolythiosulfinyl derivatives of carbamate esters. The preparation of these compounds and their...
4315027 Pesticidal symmetrical and asymmetrical sulfinyldicarbamates containing a heterocyclic group  
A novel class of chemical compounds useful as pesticides consists of symmetrical and asymmetrical N,N'-sulfinyldicarbamate esters. The preparation of these compounds and their formulation to...
Matches 201 - 250 out of 297 < 1 2 3 4 5 6 >