Matches 151 - 200 out of 297 < 1 2 3 4 5 6 >
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5259701 Antifouling coating composition comprising furan compounds, method for protecting aquatic structures, and articles protected against fouling organisms  
Certain furan compounds are disclosed as being useful as marine or fresh water antifoulant compounds to be used in protective carrier compositions such as film forming polymer to protect fish nets,...
5254595 Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them  
Aryloxypropanolaminotetralins with beta-antagonist activity of the formula ##STR1## wherein R is hydrogen, hydroxy or methoxy and Ar is an optionally substituted aromatic or heteroaromatic group,...
5250565 Indole-,benzofuran-,and benzothiophene-containing lipoxygenase-inhibiting compounds  
Pro-drugs of potent 5-lipoxygenase inhibiting compounds comprise compounds of the formula ##STR1## in which A is an alkylene or alkenylene group, X is oxygen, sulfur, sulfoxyl, or substituted...
5248221 Antifouling coating composition comprising lactone compounds, method for protecting aquatic structures, and articles protected against fouling organisms  
Certain gamma lactones are disclosed as being useful as marine or fresh water antifoulant compounds to be used in protective carrier compositions such as film forming polymer to protect fish nets,...
5227399 Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis  
Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They...
5223510 Alkylaminoalkyl derivatives of benzofuran, benzothiophene, indole and indolizine, process for their preparation and compositions containing them  
The subject of the invention is benzofuran, benzothiophene, indole or indolizine compounds of general formula: ##STR1## in which: Het represents one of the groups: ##STR2## in which T,T' and...
5204109 Percutaneous gel preparation  
A percutaneous gel preparation is disclosed, which comprises a substrate having one surface thereof a crosslinked gel layer formed by crosslinking a composition comprising the following ingredients...
5198012 Phosphate activators for cyclohexenone herbicides  
A biocide composition comprises an effective amount of a biocide and an effective amount of a biocide activator selected from the group consisting of an alkyl phosphate, an alkenyl phosphate, a...
5192799 Coumaran group containing amine compounds and their acid addition salts and quaternary ammonium salts and the use thereof as anti arrhythmic agents and as psychotropic agents  
Amine represented by the following formula (1), or their acid addition salts or their quaternary ammonium salts. ##STR1## The amines of formula (1) or their pharmaceutically acceptable acid...
5190973 20-alkyl-7-oxoprostacyclin derivatives useful as pharmaceuticals  
The invention concerns 20-alkyl-7-oxoprostacyclin derivatives of general Formula I ##STR1## wherein R 1 is the residue OR 3 where R 3 means hydrogen or alkyl of 1-10 carbon atoms optionally...
5187192 Cyclobutyl derivatives having lipoxygenase inhibitory activity  
Compounds of the structure ##STR1## where M is a pharmaceutically acceptable cation or a metabolically cleavable group, R is alkyl, cycloalkyl or --NR 1 R 2 , where R 1 and R 2 are hydrogen,...
5171751 Benzofuran/benzofuranalkyl-N-terminal amino hydroxy  
Non-peptidyl compounds characterized generally as benzofuran/benzofuranalkyl-N-terminal amino hydroxy β-amino acid derivatives are useful as renin inhibitors for treatment of hypertension....
5169860 Antitumor compositions and methods of treatment  
This invention provides the use of certain benzofuransulfonamide, benzothiophenesulfonamide, and indolesulfonamide derivatives in the treatment of susceptible neoplasms in mammals. Also provided...
5167952 Therapeutic composition formulated as a dental rinse that stimulates Prostaglandin synthesis in the mouth to prevent plaque buildup on the teeth and Periodontal disease  
This invention relates to novel oral compositions for dental hygiene in the form of a dental rinse and methods of application, effective in the prevention of the formation and buildup of dental...
5166212 Certain n-substituted butyramide derivatives  
Disclosed are compound of the formula ##STR1## wherein X and Y independently represent hydroxymethyl; cyano; carboxy; functionally modified carboxy selected from esterified carboxy, carbamoyl, and...
5162370 Treatment of cataract with prostacyclin compounds  
A method for treatment of cataract which comprises administering, to a subject in need of such treatment, a prostacyclin compound in an amount effective in treatment of cataract.
5145870 Aryloxyphenylpropylamines their preparation and use  
Novel aryloxyphenylpropylamines having the formula ##STR1## wherein X is H, cyano, halogen, halogenoalkyl, C 1 -6 -alkoxy, C 1 -6 -alkyl, C 1 -5 -alkanoyl, C 3 -5 -alkylene, aryloxy or aralkoxy,...
5128348 Bicyclo(3.1.0)hexane amines and bicyclo(4.1.0)-heptane amines as agricultural fungicides  
Certain hexane and heptane amines including geometric and stereoisomers, agricultural compositions containing them and their use as fungicides.
5110825 Benzofuran derivative  
The compounds of the present invention inhibit HMG-CoA reductase, subsequently suppress the synthesis of cholesterol; and are useful in the treatment of hypercholesterolemia, hyperlipoproteinemia,...
5104861 7-oxoprostacyclin derivatives which are useful as pharmaceuticals  
The invention relates to 7-oxoprostacyclin derivatives of Formula I ##STR1## wherein R 1 is the residue OR 3 wherein R 3 can mean hydrogen or alkyl of 1-10 carbon atoms optionally substituted by...
5102909 Pharmaceutically useful furyl substituted dihydroxyethylbutyrolactones  
The compounds 2-(5-methylthiomethyl-2-furyl)-2-hydroxy-3-keto-4- dihydroxyethylbutyrolactone and 2-(5-methoxymethyl-2- furyl)-2-furyl(-2-hydroxy-3-keto-4-dihydroxyethylbutyrolacto ne and...
5098933 Pharmaceutically useful Michael addition products of unsaturated aldehydes and ketones and ascorbic acid  
Michael addition products of ascorbic acid and selected unsaturated aldehydes and ketones are useful as immunomodulators in mammals.
5096911 Alteration of rate and character of hair growth  
The rate and character of mammalian hair growth is altered by the topical application to the skin of a composition containing an inhibitor of the enzyme gamma- glutamyl transpeptidase.
5093360 Retinal, derivatives and their therapeutic use  
Therapeutic as well as preventive measures to improve cosmetic conditions and to alleviate the symptoms of dermatologic disorders with retinal and its derivatives is disclosed. Cosmetic conditions...
5066480 Method of preventing or reducing adverse reactions to protamine using a thromboxane A.sub.2 receptor antagonist  
A method is provided for preventing reducing or reversing adverse reactions, such as pulmonary hypertension produced when protamine interacts with heparin, by administering a thromboxane A 2 ...
5039700 Benzofuranyl aminoalkoxyphenyl compounds  
Aminoalkoxyphenyl derivatives useful in the treatment of certain pathological syndromes of the cardiovascular system of formula: ##STR1## in which: B represents a --S--, --SO-- or --SO 2 -- group,...
5030629 Compositions and method comprising heterocyclic compounds containing two heteroatoms as membrane penetration enhancers  
A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or...
5019395 Compositions with enhanced penetration  
Penetration of various drugs through living membranes is improved by their use in transdermal compositions containing certain penetration-enhancing systems. A new delivery device is also described.
5017618 Labile derivatives of ketone analogs of 3-substituted-1-alkylamino-2-propanols and their use as beta-adrenergic blockers  
Compounds having the formula ##STR1## and their pharmaceutically acceptable acid addition salts, wherein --X-- is --O--, --CH 2 -- or --; Y is O or a derivatized keto group which is...
4970233 Treatment of Acquired Immunodeficiency Syndrome (AIDS) HTLV-111/LAV infections and Acquired Immunodeficiency Syndroms (AIDS) Related Complex (ARC)  
There is disclosed a method of treating inflammatory viral infections of Acquired Immunodeficiency Syndrome (AIDS) HTLV-111/LAV virus and Acquired Immunodeficiency Syndrome (AIDS) Related Complex...
4960771 Oxazolidinone penetration enhancing compounds  
Compositions for carrying physiologically active agents through body membranes having the structural formula I: ##STR1## where: R=H, Alkyl group containing from 1-18 carbon atoms, cycloalkyl, aryl,...
4956384 1,4:3,6-dianhydrosorbitol 2-mononitrate and 5-mononitrate esters and pharmaceutical compositions therefrom  
Isosorbide 2- and 5-mononitrate esters with aliphatic, aryl, or cynnamic acids or diacids, or with alkylcarbonyloxy substituents optionally containing an isosorbide 2- or 5-mononitrate group, are...
4952599 Phenylthioureas, phenylisothioureas, phenylcarbodiimides, pesticidal compositions containing them and their use in pest control  
Novel substituted phenylthioureas, phenylisothioureas and phenylcarbodiimides of formula I ##STR1## wherein R 1 is C 1 -C 10 alkyl, unsubstituted or substituted by one or more halogen atoms...
4943307 Plant-protective pesticidal composition  
The invention relates to a plant-protective solution containing 2.5 to 40 % by weight of one or more water-insoluble plant-protective ingredient(s) 20 to 71.5 % by weight of dimethylformamide...
4939141 (Fused) benz (thio) amides and pharmaceutical compositions, thereof  
A (fused) benz(thio)amides of the general ##STR1## (wherein, symbol A represents a single bond or a group of methylene, ethylene, trimethylene, tetramethylene, vinylene, propenylene, butenylene,...
4937264 Antihypercholesterolemic compounds  
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I)...
4912131 4,7-diacyloxybenzofuran derivatives  
4,7-Diacyloxybenzofuran derivatives of Formula I, are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic...
4891373 Aminopropanol derivatives of 1,4:3,6-dianhydrohexitol nitrates, processes for their preparation and their use as medicaments  
Novel aminopropanol derivatives of 1,4:3,6-dianhydro-hexitol nitrates of the general formula I ##STR1## in which X has the meaning given in the specification, processes for their preparation and...
4888351 3-phenoxy (or phenylthia) cyclopentanecarbonylamino acid analogues  
This invention relates to compounds presented by the general formula: ##STR1## [wherein R 1 and R 2 are: (i) R 1 , R 2 and carbon atoms to which R 1 and R 2 are linked, together represent the...
4886820 Dihydropyridine combination product comprising a dihydropyridine compound and a cardioactive nitrate  
A solid medicament formulation which can be administered orally, comprising 1 to 40 mg of a dihydropyridine of the formula ##STR1## in which R 1 and R 3 are always different from one another and...
4885299 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acids antihypoxic and nootropic effects having  
The invention relates to new 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid compounds of general formula I: ##STR1## in which: R 1 denotes a hydrogen atom, a linear or branched alkyl radical...
4883813 Method of treating inflammation in mammals utilizing ketobutyrolactones and furylbutyrolactones  
Treatment of inflammation in mammals utilizing selected ketobutyrolactones and furylbutyrolactones. Treatment is applicable to both acute or chronic inflammation. Antiviral activity of...
4873259 Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds  
Compounds of the formula: ##STR1## wherein R 1 is (1) hydrogen, (2) C 1 to C 4 alkyl, (3) C 2 to C 4 alkenyl, or (4) NR 2 R 3 , wherein R 2 and R 3 are independently selected from (1)...
4868153 Treatment of allograft rejection with mycophenolic acid, its morpholinoethylester and derivatives thereof  
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically...
4863949 Aminopropanol derivatives, processes for the preparation thereof, the use thereof and pharmaceutical compositions containing them  
The present invention provides compounds of the general formula: ##STR1## wherein Ar is a substituted or unsubstituted aromatic or heteroaromatic radical, A is a straight-chained or branched...
4859700 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid compounds having antihypoxic and nootropic effects  
The invention relates to new 2-(2,3-dihydro-2-oxo-3-benzofuranyl)acetic acid compounds of general formula I: ##STR1## in which: R 1 denotes a hydrogen atom, a linear or branched alkyl radical...
4857305 N-phenylphthalisoimides as ultraviolet radiation absorbers  
A class of N-phenylphthalisoimides is provided which demonstrate broad spectrum ultraviolet radiation absorbing capacities for protecting various substrate materials including plastics, fibers,...
4847286 Cromoglycic acid derivatives, method of production thereof and pharmaceutical composition  
Cromoglycic acid derivatives of the general formula ##STR1## wherein R 1 is an α-, β- or γ-amino acid residue (for ester bonding) whose amino group may optionally be substituted by at least one...
4845123 Reduction in vivo of the inappropriate levels of endogenous and environmental-derived compounds by sustained-release inhibitors of β- g  
A method for the reduction in vivo of the inappropriate levels of endogenous and environmental-derived compounds by inhibiting the activity of β-glucuronidase in a mammal which comprises the...
4816481 Method for improving cerebral circulation  
Disclosed herein is a cerebral-circulation-metabolism-function-improving agent which contains a 2,6-diphenyl-3,7-dioxabicyclo[3.3.0]octane derivative represented by the following formula as the...
Matches 151 - 200 out of 297 < 1 2 3 4 5 6 >