Matches 501 - 550 out of 681 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >
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4575512 7-Oxabicycloheptane substituted oxa prostaglandin analogs and their anti-thrombotic compositions and methods  
7-Oxabicycloheptane substituted prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful,...
4574128 5-(4-Chloro-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarboxylic acids and their compositions having diuretic, saluretic and uricosuric activity  
5-(4-Chloro-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarb oxylic acids of the formula I ##STR1## in which R 1 and R 2 are identical or different and represent hydrogen, halogen or methyl, both...
4568691 Anti-inflammatory esters of 4-(1-hydroxy-2-[(acylamino)-alkylamino]-ethyl)-phenol derivatives, compositions, and method of use therefor  
The invention concerns novel esters of 4-(1-hydroxy-2-[(acylamino)alkylamino]ethyl)phenols of the formula: ##STR1## and salts thereof, wherein R 1 and R 2 are (3-5C)alkyl, R 3 and R 4 are...
4565827 7-Substituted PGI.sub.2 -derivatives and pharmaceutical compositions containing them  
The invention relates to new, 7-substituted PGI 2 -derivatives of formula (I) ##STR1## The new compounds have valuable therapeutical properties, and in particular show prostacyclin-like effects.
4565828 Benzofuran derivatives and their therapeutic use  
Benzofuran derivatives represented by the general formula: ##STR1## in which: R represents an ethyl, n-propyl, isopropyl or n-butyl radical; R 1 represents a branched-chain alkyl radical having...
4563476 Substituted 5-hydroxy-2,3-dihydrobenzofurans and analogs thereof useful as anti-inflammatory agents  
Substituted 5-hydroxy-2,3-dihydrobenzofuran and analogs such as the substituted 6-hydroxy-2,3-dihydrobenzopyrans were prepared from an appropriately substituted...
4558043 Heterocyclicamino containing benzofurans and 2,3-dihydrobenzofurans, compositions and use  
Benzofurans or 2,3-dihydrobenzofurans of the formula ##STR1## in which R 1 represents hydrogen or an aliphatic radical, R 2 represents an amino group disubstituted by a bivalent aliphatic...
4551472 Unsymmetrical bis-carbamate compounds  
Unsymmetrical N-substituted bis-carbamoyl sulfide compounds exhibit exceptional broad spectrum pesticidal activity coupled with extremely low mammalian toxicity and phytotoxicity.
4550121 (2-Substituted-2,3-dihydrobenzo-furan-7-yl)diazenecarboxylic acid esters and miticidal method  
Certain miticidal (2-substituted-2,3-dihydro-benzofuran-7-yl)diazenecarboxylic acid esters.
4550120 7-Oxabicycloheptane substituted ethers and their use in treating thrombolytic disease  
7-Oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein A is O or ##STR2## and including all stereoisomers thereof. The compounds are...
4542156 7-Oxabicycloheptane substituted prostaglandin alcohols and their use in the treatment of thrombolytic disease  
7-Oxabicycloheptane substituted prostaglandin alcohols are provided having the structural formula ##STR1## wherein A is --CHCH--(CH 2 ) n -- or (CH 2 ) q ; B is a single bond or --CHCH--; n...
4540708 Sulfenyl carbamate derivatives and insecticidal compositions containing the same  
A sulfenyl carbamate derivative represented by the formula ##STR1## wherein Ar represents ##STR2## R 1 represents --X--COO--R 3 or --Y--CN in which X and Y is each an alkylene group having 1 to 6...
4539333 Prostacyclin, methods of using and method of making  
Prostacyclin, its salts, biosynthesis and synthesis thereof, pharmaceutical formulations containing them, and their use in medicine.
4537904 Compositions of 7-oxabicycloheptane and 7-oxabicycloheptene compounds and a method for their use in inhibiting bronchoconstriction  
7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular...
4536513 7-Oxabicycloheptane substituted prostaglandin interphenylene analogs useful in the treatment of thrombolytic disease  
7-Oxabicycloheptane substituted interphenylene prostaglandin ethers are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular...
4536330 1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters and cyclic condensation products thereof, organoleptic uses of same and processes for preparing same  
Described are 1-hydroxymethyl-2-acyl cyclopropane derivatives defined according to the structure: ##STR1## wherein Z represents hydrogen, acyl having the structure: ##STR2## and substituted oxyacyl...
4535086 4,5,6,7-Tetrahydro-4,4,7,7-tetramethylbenzo[b]thien-2-yl or furan-2-yl derivatives  
Heterocyclic compounds of the formula ##STR1## wherein X is --CHCH--, --O-- or --S--; R 1 is a group Ar--R 2 or --CHCH--C(CH 3 )CH--R 21 ; Ar is phenyl, pyridyl, furyl or thienyl; R 2 ...
4533673 7-Oxabicycloheptane substituted enaminone prostaglandin analogs and their use in treatment of thrombolytic disease  
7-Oxabicycloheptane substituted enaminone prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4532236 Certain prostacyclins and their blood-pressure-lowering and thrombocyte-aggregation-inhibiting compositions and methods  
Prostacyclin derivatives of general Formula I ##STR1## wherein R 1 is the residue OR 3 wherein R 3 means hydrogen or alkyl of 1-10 carbon atoms substituted, if desired, by halogen, aryl, C 1 -C...
4532256 Pesticidal N-methyl-carbamic acid esters  
N-Methyl-carbamic acid esters of the formula ##STR1## wherein R 1 is unsubstituted or substituted 2,3-dihydrobenzofuranyl, phenyl, naphthyl or ##STR2## R 2 is hydroxyl, halogen, --OR 1 , C 1 -C...
4526901 7-Oxabicycloheptane substituted oxamide prostaglandin analogs and their use in treating thrombolytic disease  
7-Oxabicycloheptane substituted oxamide prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4525479 7-Oxabicycloheptane substituted thiocarbamate prostaglandin analogs useful as cardiovascular agents  
7-Oxabicycloheptane substituted thiocarbamate prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular...
4524150 Stabilized mixtures of carbamate insecticides and synthetic pyrethroids  
Pesticidal mixtures of carbamate insecticides and synthetic pyrethroids can be improved by the addition of stabilizers to prevent racemization of the pyrethroid to a less pesticidally-active...
4524151 7-Oxabicycloheptane thio ethers useful as cardiovascular agents  
7-Oxabicycloheptane ethers of prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for...
4520018 5-Substituted-4-oxo-PGI.sub.1 derivatives, PGI.sub.1 compounds of similar structure, their pharmaceutical methods and process for the preparation of said compounds  
New PGI 1 derivatives are disclosed as well as a process for the preparation thereof, pharmaceutical compositions containing same and methods of treatment employing same. The new compounds are...
4518609 Naphtenic and heterocyclic retinoic acid analogues  
Naphthenic and heterocyclic retinoic acid analogues such as (E)-6-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-2-napht haldehyde, methyl...
4517183 N-Substituted aziridine-2-carboxylic acid derivatives  
The present invention provides pharmaceutical compositions containing N-substituted aziridine-2-carboxylic acid derivatives of the general formula: ##STR1## wherein X is a carboxyl, a cyano, an...
4513103 7-Oxabicycloheptane ethers useful in the treatment of thrombolytic disease  
7-Oxabicycloheptane ethers of prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for...
4511578 Acyclamidosulfenylcarbamates for controlling insects  
A composition for controlling insects, particularly for controlling insects which infest plants and animals, which composition contains, as active ingredient, a compound of the formula I ##STR1##...
4507292 Combating pests with aryl N-oxalyl-N-methyl-carbamates  
Aryl N-oxalyl-N-methyl-carbamates of the general formula ##STR1## in which X represents an alkoxy, alkenoxy, alkinoxy, aryloxy, alkylthio, alkenylthio, alkinylthio or arylthio radical, each of...
4503068 Use of prostaglandin analogues to treat cytodamage  
The prostaglandin analogues 16S-methyl-6-oxo-PGE 1 methyl ester, 17S,20-dimethyl-6-oxo-PGE 1 methyl ester, 15S-methyl-6-oxo-PGE 1 and non-toxic salts thereof, ...
4503069 N-Alkylidene -imino-oxycarbonyl-N-methyl-[2,2-dimethyl-2,3-dihydrobenzofuranyl(7)]-car bamates and their use for controlling pests  
N-Alkylidene-imino-oxycarbonyl-N-methyl-[2,2-dimethyl-2,3-di hydrobenzofuran yl(7)]-carbamates ##STR1## wherein R 1 and R 2 independently of one another are each an alkyl group, or together they...
4500543 Substituted 1-aminomethyl-phthalans  
Disclosed herein are 1-aminomethyl-phthalans represented by the formula ##STR1## wherein R, R 1 , and R 2 are independently selected from hydrogen, hydroxy, loweralkoxy of 1 to 3 carbon atoms,...
4499085 Method of anoxia treatment using prostaglandin analogues  
The invention provides a new method for the treatment of anoxia of brain cells using a PGI 1 derivative of the formula: ##STR1## wherein R 1 represents hydrogen or lower alkyl and R 2 represents...
4485112 N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions  
A 2-substituted benzofuran derivative of general formula I or II ##STR1## in which R 1 and R 2 , can be the same or different, and are a hydrogen atom, a halogen atom, an alkyl group containing 1...
4485111 Derivatives of 3-amino-1-benzofuranyloxy-2-propanol useful as cardioselective beta-blocking agents  
The present invention relates, as new industrial products, to (±)-, (+)- and (-)-2,4-diacetyl-5-(3-alkyl-amino-2-hydroxy-propyloxy)-benzo furans of general formula: ##STR1## where R is CH(CH 3 ) 2...
4479945 Inter-m-phenylene-prostacyclin analogues and use thereof in inhibiting blood platelet aggregation  
New inter-m-phenylene-PGI 2 derivatives are prepared of the general formula I ##STR1## wherein R 1 stands for hydrogen, alkyl containing 1 to 4 carbon atoms or a pharmaceutically acceptable...
4479944 Composition containing PGI.sub.2 analogs stabilized  
Compositions which contain a PGI 2 analogue in solution in a solvent consisting of at least one pharmacologically-acceptable alcohol, polar aprotic solvent or middle chain triglyceride, or which...
4474804 7-Oxabicyclo substituted prostaglandin phenyl carboxylic acid derivatives useful as cardiovascular agents  
7-Oxabicyclo substituted prostaglandin phenyl carboxylic acid derivatives are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are...
4473580 N-Imidoylthio(methyl)carbamates and methods for controlling insects  
This invention pertains to some new organic compounds, to a process for preparing them, and to formulations of them suitable for pesticidal use. The invention is more particularly directed to...
4472429 N-(3-Trimethylstannylpropyl)carbamates and use thereof in pest control  
There are disclosed novel N-(3-trimethylstannylpropyl)carbamates, a process for their preparation and their use in pest control. These carbamates have the formula (CH 3 ) 3 SnCH 2 CH 2 CH 2 ...
4472428 Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore  
Novel 5- or 7-monohalogenated or 5,7-dihalogenated 6 -PGI 1 and 5- or 7-monohalogenated or dihalogenated PGI 2 (except 5-monofluorinated PGI 2 ). The novel halogenated prostacyclins are useful...
4466979 7-Oxabicycloheptane substituted carbamate prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction  
7-Oxabicycloheptane substituted carbamate prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4463015 Aryl substituted 7-oxabicycloheptane compounds, useful in inhibiting platelet aggregation  
7-Oxabicycloheptane and prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful, for...
4456617 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction  
7-Oxabicycloheptane substituted amino prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4456616 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction  
7-Oxabicycloheptane substituted amino prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents...
4454158 Allyl amine MAO inhibitors  
Compounds of the formula ##STR1## wherein: R is phenyl, phenyl monosubstituted, disubstituted, or trisubstituted by (C 1 -C 8 ) alkyl, (C 1 -C 8 )alkoxy, hydroxy, chlorine, bromine, iodine,...
4451483 2,3,4-Trinor-m-inter-phenylene-prostaglandin derivatives and compositions and method for inhibiting blood platelet aggregation  
2,3,4-trinor-1,5-inter-m-phenylene-prostacycline derivatives of the formula (I), ##STR1## wherein R 1 is hydrogen, a C 1 -4 alkyl group, an alkali metal cation or a primary, secondary, tertiary or...
4438132 4-Oxo-PGI.sub.2 compounds, their use in inhibition of thrombii and their production  
The invention relates to a process for the preparation of novel 4-oxo-PGI 2 derivatives of formula I ##STR1## where (a) compounds of formula III ##STR2## are oxidized, then the obtained...
4435422 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions  
Described are compounds of the formula ##STR1## wherein R 1 and R 2 independently of one another denote hydrogen or loweralkyl; A is CO, CH 2 , O, S, SO or CHOH; X is hydrogen, halo, loweralkyl,...
Matches 501 - 550 out of 681 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >