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4672075 |
7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents
7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives are disclosed having the general formula ##STR1## wherein R 1 is hydrogen, lower alkyl, aryl, aralkyl or alkenyl; R 2 is hydrogen, lower...
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4670453 |
7-oxabicycloheptane substituted amido-carbamoyl prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted amidocarbamoyl prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; R...
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4668691 |
Circulation-active novel 7-aryl-or pyridyl-1-oxo-1,c,4,7-tetrahydrobenzofurans
1-Oxo-1,3,4,7-tetrahydrobenzofuranes of the formula ##STR1## in which X is O or S, R is optionally substituted phenyl or heteroaryl, R 1 is OH, monoalkylamino or dialkylamino, and R 2 is...
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4666931 |
Benzofuran derivatives useful in treating diabetic complications
A benzofuran derivative having the general formula (I): ##STR1## wherein R 1 is hydrogen atom, a benzyl group, unsubstituted or substituted with a halogen atom or an alkyloxy group, or an alkyl...
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4665088 |
(E-Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxides
This invention relates to compounds of the structures: ##STR1## which structure includes its isomers, conventionally designated (E,Z)-4,5,9-trithiadodeca-1,6,11-triene 9-oxide and commonly termed...
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4663347 |
Benzofuran 2-carboxylic acid esters useful as inhibitors of leukotriene biosynthesis
Compounds of the Formula I: ##STR1## and pharmaceutically acceptable salts thereof are inhibitors of leukotriene biosynthesis. These compounds inhibit the mammalian 5-lipoxygenase enzyme, thus...
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4663336 |
7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q is...
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4663337 |
7-oxabicycloheptane substituted amides useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted amides are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; R is CO 2 H, CO 2 alkyl, CO 2 ...
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4661506 |
7-oxabicycloheptane substituted ox prostaglandin analogs
7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula ##STR1## wherein R 1 is lower alkyl, aryl, aralkyl, cycloalkyl or cycloalkylalkyl, A is...
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4659709 |
2,3-dihydrobenzofuran-5-sulfonamide derivatives useful as antihypertensive diuretic agents
Highly effective diuretic antihypertensives, i.e., 2,3-dihydrobenzofuran-5-sulfonamide derivatives which is classified to loop diuretics with less adverse side-effects and can be administered...
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4659735 |
Benzofuranyl (thienyl) propenyl derivatives useful as rodenticides
Heterocyclic compounds of the formula ##STR1## wherein X is --CHCH--, --O--or --S--; R 1 is a group Ar--R 2 or --CHCH--C(CH 3 )CH--R 21 ; Ar is phenyl, pyridyl, furyl or thienyl; R 2 ...
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4656185 |
7-oxabicycloheptane substituted aminoalkyl amide prostaglandin analogs
7-Oxabicycloheptane substituted diacid diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; R...
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4656163 |
Compositions and methods of combating pests employing sulphenic acid amides in combination with known nematicides or insecticides
The present invention relates to the use of the sulphenic acid amides of the general formula (I) ##STR1## in which X represents identical or different halogen atoms, Y 1 and Y 2 are identical...
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4654355 |
7-oxabicycloheptane substituted amide-thioamide prostaglandin analogs
7-Oxabicycloheptane substituted amide-thioamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 CH 2 --; n is 1 to 5; Q...
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4654365 |
2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury
The invention relates to novel substituted 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxyl
ic acids, their derivatives and their salts. The compounds are useful for the treatment and...
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4654357 |
7-oxabicycloheptane substituted sulfonamide prostaglandin analogs
7-Oxabicycloheptane substituted sulfonamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q is...
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4654366 |
Hydroxamic acids of 7-oxabicyclo[2.2.1]heptane substituted ethers useful as anti-thrombotic agents
7-Oxabicycloheptane substituted ether or thio ether prostaglandin analogs are provided having the structural formula ##STR1## wherein A is O or ##STR2## and X is O or ##STR3## and including all...
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4654362 |
Derivatives of 2,2'-iminobisethanol
Derivatives of 2,2'-iminobisethanol having useful properties in the treatment and/or the prevention of disorders of the coronary-vascular system.
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4654356 |
7-oxabicycloheptane substituted diacid diamide prostaglandin analogs
7-Oxabicycloheptane substituted diacid diamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
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4654367 |
Hydroxamic acids of 7-oxabicycloheptane substituted ethers useful as anti-allergy and anti-inflammation agents
Hydroxamic acids of 7-oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein Q is --CH 2 --A--(CH 2 ) n --; X is S or O, Y is O or...
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4652576 |
7-oxabicycloheptane substituted amide-carbamate prostaglandin analogs
7-Oxabicycloheptane substituted amide-carbamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
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4652578 |
7-oxabicycloheptane substituted amide prostaglandin analogs
Cis-exo 7-oxabicycloheptane substituted amide prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; R is CO 2 H, CO...
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4650811 |
Ethenylphenol-indoles having antiarythmic utility
Novel ethenylphenol indoles of the formula ##STR1## wherein R and R 1 are individually selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms, cycloalkyl of 3 to 7 carbon...
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4647573 |
7-oxabicycloheptane substituted thioamide-amide prostaglandin analogs
7-Oxabicycloheptane substituted thioamideamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q...
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4643994 |
Novel organic trithio oxides and method for the preparation thereof
This invention relates to novel organic trithio oxides of the formula: R 1 --X --R--X 1 --R 1 wherein R is selected from --CH 2 CHCH--, ##STR1## and (CH 2 ) 3 ; X is selected from ##STR2##...
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4639461 |
7-oxabicycloheptane substituted keto-amide prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted keto-amide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; Q is...
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4638002 |
2,3,4-trinor-1,5-inter-meta-phenylene-prostacyclin compounds useful in inhibiting thrombocyte aggregation
The invention relates to new 2,3,4-trinor-1,5-inter-m-phenylene-PGI 2 derivatives of the formula (I) ##STR1## wherein A stands for carboxy, cyano, tetrazolyl or --COOR 3 or --CONR 1 R 2 ; R...
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4638012 |
7-oxabicycloheptane α-substituted ketone prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane α-substituted ketone prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5; X is...
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4636523 |
Insecticidal urea substituted 2,3-dihydro- benzofuran and benzothiophene derivatives, compositions, and method of use thereof
Insecticidal compounds of the formula ##STR1## in which A and B are both halogen or hydrogen, or one of A and B is hydrogen, and the other of A and B is halogen; Z and W are independently O or S;...
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4636505 |
Amide derivatives
Acylanilides of the formula ##STR1## wherein R 1 and R 2 , the same or different, each is cyano, carbamoyl, nitro, halogeno, perfluoroalkyl or other defined substituents; R 3 is hydrogen or...
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4634701 |
Furan derivatives having anti-ulcer activity
Compounds of formula (I): ##STR1## wherein: A represents a CH-NO 2 group or a N-CN group; B represents CH 2 , O, S or a direct bond; R represents a bicyclic or polycyclic residue, variously...
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4632931 |
7-oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted amide-sulfonamide prostaglandin analogs are provided having the structural formula ##STR1## wherein m is 0 to 4; A is --CHCH-- or --CH 2 --CH 2 --; n is 1 to 5;...
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4626548 |
7-oxabicycloheptane substituted prostaglandin compounds useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted prostaglandin alcohols are provided having the structural formula ##STR1## wherein A is --CHCH-- or (CH 2 ) 2 ; m is 1 to 5; Q is --CHCH-- or (CH 2 ) 2 ; R...
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4616035 |
Pesticidally active novel N-oxalyl derivatives of N-methylcarbamates
Combating pests such as insects, arachnids and nematodes with novel N-oxalyl-N-methylcarbamic acid esters of the formula ##STR1## in which R represents alkyl, alkenyl, alkinyl, alkoxy, alkylthio,...
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4613611 |
Method of treating diabetes mellitus using arylglyoxals
A method of treating diabetes mellitus using arylglyoxals which are known compounds.
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4613614 |
Prostaglandin I.sub.2 ester and fat emulsion containing the same
There is provided a new ester of prostaglandin of the formula ##STR1## wherein R 1 denotes an alkyl group having 1 to 20 carbon atoms; R 2 denotes a hydrogen atom or a lower alkyl group having 1...
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4611007 |
7-oxabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease
7-Oxabicycloheptane substituted prostaglandin analogs are provided having the structural formula ##STR1## and including all stereoisomers thereof. The compounds are cardiovascular agents useful,...
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4610983 |
N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same
This invention relates to a novel N-acyl acidic amino acid diamide derivative represented by the general formula or a salt thereof: ##STR1## wherein each of R 1 , R 2 , R 3 and R 4 , which may be...
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4609648 |
Halogenoalkylcarbamic acid ester pesticides
Halogenoalkylcarbamic acid esters of the formula ##STR1## in which R, R 1 and R 2 independently of one another represent methyl which is optionally substituted by halogen, at least one of the...
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4608386 |
7-oxabicycloheptane ethers useful in the treatment of thrombotic diseases
7-Oxabicycloheptane substituted ether prostaglandin analogs are provided having the structural formula ##STR1## wherein X is O or ##STR2## and including all stereoisomers thereof. The compounds are...
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4608371 |
Combating insects with certain 2,3-dihydro-2,2-dimethyl-7-benzofuranyl N-oxalyl-N-methyl carbamates
The present invention provides novel insecticidal carbamate derivatives. The invention also provides a method for the control of insects.
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4607048 |
7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
7-Oxabicycloheptane substituted aryl amino prostaglandin analogs are provided having the structural formula ##STR1## wherein A is --CHCH-- or --(CH 2 ) 2 --; m is 1 to 8; n is 1 to 5; R is H,...
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4607049 |
7-oxabicycloheptane substituted thio prostaglandin analogs useful in the treatment of thrombolytic disease
7-Oxabicycloheptane substituted thio prostaglandin analogs are provided having the structural formula ##STR1## wherein R is hydrogen, lower alkyl, alkali metal, or a polyhydroxylamine salt, R 1 is...
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4602035 |
Antidepressant (3-aryl-2,3-dihydrobenzofuran-3-yl)alkylamines
There are described compounds of the formula ##STR1## where n is 2 or 3, X and Y are each independently hydrogen, loweralkyl, or halogen, and R 1 and R 2 are each independently hydrogen,...
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4602033 |
Combating pests with aryl N-oxalyl-N-methylcarbamates
Aryl N-oxalyl-N-methyl-carbamates of the general formula ##STR1## in which X represents an alkoxy, alkenoxy, alkinoxy, aryloxy, alkylthio, alkenylthio, alkinylthio or arylthio radical, each of...
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4588743 |
7-oxabicycloheptane-substituted oxa prostaglandin analogs and their use in the treatment of thrombolytic disease
7-Oxabicycloheptane substituted oxa prostaglandin analogs are provided having the structural formula ##STR1## wherein R is OH, ##STR2## (wherein R 3 is lower alkyl, aryl, arylalkyl or lower...
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4587259 |
Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters
Certain miticidal 2-(2-alkyl-2,3-dihydro-benzofuran-7-yl)-hydrazinecarboxylic acid esters.
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4582854 |
7-oxabicycloheptane substituted oxa prostaglandin analgos useful in the treatment of thrombolytic disease
7-Oxabicycloheptane substituted oxo prostaglandin analogs are provided having the structural formula ##STR1## wherein R is hydrogen, lower alkyl, alkali metal or trihydroxymethylaminomethane, R 1 ...
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4579865 |
Benzofuranyl carbamates
Compounds of the structure; ##STR1## and pharmaceutically acceptable salts thereof, wherein: R 1 is H, alkyl, alkoxy, carboxyl, alkylcarboxy, trifluoromethyl, halogen, nitro or hydroxy; X is...
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4579581 |
Biologically active amide derivatives
Herbicidal and fungicidal benzamide derivatives of the formula (I) ##STR1## wherein R 1 is an optionally substituted alkyl, alkenyl, aryl, heterocyclyl, benzyl, or heterocyclylmethyl radical; R...
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