|
Match
|
Document |
Document Title |
|
|
7601712 |
Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient
A compound represented by formula (I)
wherein the symbols in the formula are the same meanings as those in specification, salts thereof, solvates thereof, or prodrugs thereof binds to DP...
|
|
|
7598417 |
Substituted fluoroethyl ureas as alpha 2 adrenergic agents
The present patent application is directed to novel fluoroethyl urea compounds and compositions and their therapeutic use in the treatment of pain and other conditions.
|
|
|
7576125 |
Melanogenesis inhibitor and skin preparation containing the same
A melanogenesis inhibitor characterized by containing at least one kind of piperonyl alcohol represented by the following general formula (1)
wherein R is a straight chain or branched chain...
|
|
|
7572817 |
2,5-disubstituted 3-mercaptopentanoic acid
The present invention concerns compounds of formula (I), and pharmaceutically acceptable salts or solvates thereof, or solvates of such salts, which compounds inhibit carboxypeptidase U and thus...
|
|
|
7553834 |
Method for the targeted treatment of depression
A method for determining the appropriate medication for a patient suffering from depression. A patient will take a questionnaire wherein the patient answers a number of questions with scaled...
|
|
|
7524884 |
Compacted 2,2-dibromo-3-nitrilopropionamide
The present invention provides an essentially pure compacted 2,2-Dibromo-3-nitrilopropionamide (DBNPA) in a granular and/or tablet and/or briquette and/or pellet form. The present invention further...
|
|
|
7491748 |
Carboxylic acid derivative compounds and drugs comprising these compounds as the active ingredient
A carboxylic acid derivative of formula (I):
wherein R 1 is —COOH, —COOR 6 , etc.; A is a single bond, alkylene, etc.; R 2 is alkyl, alkoxy, etc.; B is a carbocyclic ring or a...
|
|
|
7470722 |
Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease
Disclosed herein are carbonyl compounds of Formula I as described herein.
Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune...
|
|
|
7453010 |
Phenylcyclohexylpropanolamine derivatives, preparation and therapeutic application thereof
The invention relates to compounds of general formula (I):
where R 1 represents H or a (C 1 -C 4 )alkyl, —CO(C 1 -C 4 )alkyl, (C 1 -C 4 )alkylphenyl or —CO-phenyl group, said phenyl...
|
|
|
7452556 |
Compositions for the treatment of pilosebaceous gland inflammations comprising aluminum fluoride
The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and...
|
|
|
7442718 |
Inhibitors of aspartyl protease
The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors...
|
|
|
7354911 |
1,3-benzodioxol compound and use of same
Containing the 1,3-benzodioxol compound represented by the formula (I):
together with a pesticidal active ingredient in a pesticidal composition enhances a pest control effect of the pesticidal...
|
|
|
7345068 |
Aromatic amino acid derivatives and medicinal compositions
1. An aromatic amino acid derivative represented by the formula (I) or its pharmacologically acceptable salt:
wherein,
R 1 is a hydrogen atom or an amino-protecting group, R 2 is a...
|
|
|
7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
|
|
|
7265130 |
NPY Y5 antagonist
The present invention provides a pharmaceutical composition for use as an NPY Y5 receptor antagonist comprising a compound of the formula (I):
wherein R 1 is lower alkyl, cycloalkyl or the...
|
|
|
7256218 |
Biguanide and dihydrotriazine derivatives
Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine...
|
|
|
7256204 |
Amine compounds, their production and use
A compound of the formula:
wherein Ar is an aromatic ring assembly group which may be substituted or a fused aromatic group which may be substituted; X is (i) a bond, (ii) —S—, —SO— or...
|
|
|
7220752 |
Compounds active at the glucocorticoid receptor II
This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in therapy...
|
|
|
7157495 |
Hexahydrofuro[2,3-B]furan-3-YL-N-{3-[(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino]-1-benzyl-2-hydroxypropyl}carbamate as retroviral protease inhibitor
Compositions comprising bis-tetrahydrofuran benzodioxyolyl sulfonamide compounds that are surprisingly effective protease inhibitors and a second antiretroviral compound are disclosed. Methods of...
|
|
|
7148242 |
N-formyl hydroxylamine compounds, compositions and methods of use
N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylami
no-aryl or -heteroaryl)-azacyclo 4-7 alkanes or thiazacyclo 4-7 alkanes or imidazacyclo 4-7 alkanes have interesting properties, e.g.,...
|
|
|
7141686 |
E2, E4, Z8-undecatrienoic acid and ester and carboxamide derivatives thereof, organoleptic uses thereof and processes for preparing same
Described is a genus of E2,E4,Z8-undecatrienoic acid derivatives defined according to the structure:
wherein Z represents —OR″ or —NRR′ with the provisos that when Z is —OR″, R″...
|
|
|
7078431 |
1,3-bis-(substituted-phenyl)-2-propen-1-ones and their use to treat VCAM-1 mediated disorders
It has been discovered certain 1,3-bis-(substituted-phenyl)-2-propen-1-ones, including compounds of formula (I) inhibit the expression of VCAM-1, and thus can be used to treat a patient with a...
|
|
|
7078057 |
Process for producing nanometer particles by fluid bed spray-drying
Nanometer particles of poorly water-soluble or substantially water-insoluble compound are produced by finely-spraying a non-aqueous solution of said compound into a heated and fluidized bed of...
|
|
|
7045518 |
Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention...
|
|
|
7037914 |
Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient
A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I)
(wherein all symbols are as defined in the specification), a non-toxic acid...
|
|
|
7019028 |
Endiandric acid H and its derivatives, process for their preparation and use thereof
The invention relates to compounds of the formula (I)
process for their preparation starting from the plant Beilschmiedia fulva , PLA 101037, and the use thereof for producing a medicament, in...
|
|
|
6974832 |
L-ascorbic acid and pectin composition
The invention relates to compositions in the form of a powder or granules containing L-ascorbic acid and/or a pharmaceutically acceptable salt thereof, and pectin in a quantity within the range of...
|
|
|
6964968 |
Method for the treatment or prevention of viral infection using nucleoside analogues
Viral infections selected from the group consisting of herpes simplex virus, varicella zoster virus, respiratory syncytial virus and cytomegalovirus can be treated by administering to the host a...
|
|
|
6946462 |
N-monoacylated derivatives of o-phenylenediamines, their analogs and their use as pharmaceutical agents
New compounds represented by the formula
or pharmaceutically acceptable salts or prodrugs thereof,
wherein
X 1 and X 2 are each independently selected from a CH group or a nitrogen atom;...
|
|
|
6943182 |
Cyclopentabenzofuran derivatives and their use
The invention relates to cyclopentabenzofuran derivatives, process for their preparation, the use of cyclopentabenzofuran derivatives for the production of a medicament for the therapy of...
|
|
|
6894074 |
Synergistic insecticidal mixtures
The invention relates to insecticidal mixtures comprising compounds of the formula (I)
in which X′, Y′, Z′, n, G′, A′ and B′ are as defined above
and agonists and/or antagonists...
|
|
|
6867218 |
Compounds, their preparation and use
The present invention relates to compounds of the general formula (I)
The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the...
|
|
|
6864282 |
9,11-cycloendoperoxide pro-drugs of prostaglandin analogues for treatment of ocular hypertension and glaucoma
9,11-Cycloendoperoxide derivatives of biologically active prostaglandin analogs, and particularly of the ocular hypotensive drugs Bimatoprost, Latanaprost, Unoprostone, Travoprost and prostaglandin...
|
|
|
6858648 |
Laetispicine and laetispicine analogues, methods of use and preparation
A compound having the following Formula:
wherein R1, R2, Z, and Y are defined herein, and methods of preparation and application for treating mental disorders and inflammation are provided...
|
|
|
6849645 |
Method of increased bioavailability of nutrients and pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives
Tetrahydropiperine and analogs and derivatives thereof, including dihydropiperine, are disclosed to enhance the absorption and/or bioavailablity of nutrients, drugs and other organic compounds,...
|
|
|
6838477 |
Lactacystin analogs
Described herein are compounds related to lactacystin and lactacystin β-lactone, pharmaceutical compositions containing the compounds, and methods of use.
|
|
|
6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
|
|
|
6787559 |
Sulfonamide compounds
This invention relates to certain sulfonamide derivatives that are inhibitors of procollagen C-proteinase, pharmaceutical compositions containing them, methods for their use and methods for...
|
|
|
6780887 |
Anti-ischemic compounds
The present invention is related to a compound of formula (I), salts and pro-drugs of the compound (I) and methods for treating and/or preventing partial or total ischemia, methods for treating...
|
|
|
6773727 |
Use of gossypol and related terpenes for control of urban and agricultural pests
Low concentrations of gossypol and related phyllophage toxins from cotton improve the effectiveness of insecticidal agents against social insects, including cockroaches, and particularly termites...
|
|
|
6773702 |
Use of combretastatin A4 and its prodrugs as an immune enhancing therapy
A method of treating immune suppression in a warm-blooded animal bearing a tumor, by administering to the animal an amount of combretastatin A4 and/or a prodrug thereof effective to enhance immune...
|
|
|
6767921 |
Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them
The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylprop
ionyl-amino)propionate, hereinafter...
|
|
|
6740665 |
Tyrosine kinase inhibitors and methods of using the same
Tyrosine kinase inhibitors and pharmaceutical composition comprising the same are disclosed. Methods of treating mammals who have p185 tumors and methods of preventing p185 tumors in mammals at...
|
|
|
6730705 |
Alkoximino acetic acid amides
The invention relates to new alkoximinoacetic acid amides, a process for their preparation and their use as agents for combating pests.
|
|
|
6699911 |
Catalytic reduction of alkyne compounds
A process is provided for the preparation of cyclohexene derivatives of general formula I or II: in which the substituents R 1 and R 2 independently of one another are defined as follows: R 1 ...
|
|
|
6693126 |
Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases
The present invention relates to a pharmaceutical composition for the hepatoprotection and treatment of liver diseases comprising as an active ingredient a dihydroxyphenyl derivative represented by...
|
|
|
6667339 |
Vanadium (IV) complexes containing catecholate ligand and having spermicidal activity
Vanadium (IV) complexes containing a substituted or unsubstituted catecholate ligand, and the spermicidal activity of such compounds. Preferred compounds are vanadocene (IV) complexes containing...
|
|
|
6667307 |
Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors
Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention...
|
|
|
6660728 |
Thienyl substituted acylguanidines as inhibitors of bone resorption and vitronectin receptor antagonists
The present invention relates to thienyl substituted acylguanidine derivatives, such as compounds of formula (I) in which R 1 , R 2 , R 4 , R 6 , A, B and D have the meanings indicated in the...
|
|
|
6649651 |
Hexahydrofuro&lsqb 2,3-B&rsqb furan-3-yl-n&lcub 3&lsqb (1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino&rsqb -1-benzyl-2-hydroxypropyl&rcub carbamate as retroviral protease inhibitor
Novel bis-tetrahydrofuran benzodioxolyl sulfonamide compounds which are surprisingly effective protease inhibitors. The invention also relates to pharmaceutical compositions, methods of inhibiting...
|