|
Match
|
Document |
Document Title |
|
|
7585894 |
4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1-propenyl]benzoic acid analogs and method of manufacture and use thereof
Analogs of 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalen
yl)-1-propenyl]benzoic acid and methods of manufacture and use thereof, such as for use in cancer prevention and treatment.
|
|
|
7585865 |
Protein kinase C zeta inhibition to treat vascular permeability
Methods of treating or preventing a disease or disorder in a subject are provided by the present invention which include administering a composition including a therapeutically effective amount of...
|
|
|
7582676 |
2-phenylpyran-4-one derivatives as selective COX-2 inhibitors
The present invention relates to 2-phenylpyran-4-derivatives of general formula (I), processes for their preparation, pharmaceutical compositions containing them, and their medical uses.
|
|
|
7582674 |
Nutraceutical compositions and use thereof
Compositions including, as the active ingredients, resveratrol, a derivative, metabolite or analogue thereof, and at least one additional component selected from epigallocatechin gallate (EGCG),...
|
|
|
7579449 |
Glucopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
Glucopyranosyl-substituted benzene derivatives of general formula I
where the groups R 1 to R 6 as well as R 7a , R 7b , R 7c are defined herein and the tautomers, the stereoisomers thereof,...
|
|
|
7576225 |
6R-(3,6-dideoxy-L-arabino-hexopyranosyloxy) heptanoic acid, preparation process for the same and dauer effect thereof
The present invention relates to a determination of a stereochemistry, a synthesis and dauer effect of 6R-(3,6-dideoxy-L-arabino-hexopyranosyloxy) heptanoic acid as a pheromone isolated from the...
|
|
|
7569576 |
Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof
The present invention provides cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, methods of making cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs and compositions of cyclic 1-(acyloxy)-alkyl...
|
|
|
7566724 |
Glycine derivative and use thereof
The compounds of the disclosure, for example, the compound represented by the formula:
has excellent therapeutic and prophylactic effects against inflammatory bowel disease. Further, they are...
|
|
|
7560482 |
Inhibitors of plasmepsins
Compounds and methods for the inhibition of anti-malarial target aspartyl protease plasmepsins (e.g. Plasmepsin I, Plasmepsin II, Plasmepsin IV and HAP) are provided. The compounds are based on...
|
|
|
7538127 |
Medicinal compounds
A compound of formula (I) or a salt, solvate, or physiologically functional derivative thereof, wherein: m is an integer of from 2 to 8; n is an integer of from 2 to 5; with the proviso that m+n is...
|
|
|
7482026 |
Compositions and methods directed towards sore muscles and joints
Chemical formulations and methods for reducing muscle and joint soreness are disclosed. A representative chemical formulation includes compounds such as a selenium-compound, chondroitin sulfate,...
|
|
|
7468355 |
Methods for inhibiting cancer and scar formation
Methods for inhibiting cancer, scar formation, disrupting the cellular cytoskeleton, and conferring resistance from infection are disclosed. Such methods comprise the administration of oleuropein...
|
|
|
7442839 |
Phenethanolamine derivative for the treatment of respiratory diseases
The present invention relates to novel compounds of formula (I),
to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular...
|
|
|
7419959 |
D-pyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
D-pyranosyl-substituted phenyls of general formula I
wherein the groups R 1 to R 5 , X, Z and R 7a , R 7b , R 7c are defined as in claim 1, have an inhibiting effect on the sodium-dependent...
|
|
|
7417059 |
Substituted aromatic-ring compounds, process for producing the same and use
The present invention is directed to a class of cyclohexene derivatives bearing sulfamoyl and ester groups which have an inhibitory activity on nitric oxide (NO) production and cytokine production,...
|
|
|
7414074 |
Antiinflammatory lactones
Lactones of Formula (I) which are pharmaceutically active in diseases associated with inflammation
|
|
|
7405309 |
Pyranone derivatives useful for treating cancer
The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and R 1 and R 2 is independently a hydrogen atom, an alkyl, cycloalkyl or alkylene,...
|
|
|
7375133 |
Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a...
|
|
|
7368469 |
Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
Use of an inhibitor of the renin-angiotensin system or a pharmaceutically acceptable derivative thereof, optionally together with another antihypertensive, a cholesterol lowering agent, a diuretic...
|
|
|
7345091 |
Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease
A method for inhibiting and/or ameliorating the occurrence of diseases associated with reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals in a subject whereby a...
|
|
|
7342044 |
Preservative blends containing quaternary ammonium compounds
The present invention provides a biocidal composition comprising a synergistic mixture of certain quaternary ammonium biocides and one or more ketone acids, aromatic carboxylic acids, salts...
|
|
|
7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
|
|
|
7309502 |
Pharmaceutical compositions for treating and saving and the method for the preparation thereof
The present invention relates to a pharmaceutical composition and the method for the preparation thereof. The composition comprises 1.5˜6.9% (w/v) of one or more substances selected from sodium...
|
|
|
7304091 |
Statin-like compounds
The present invention relates to compounds with structures resembling natural statins isolated from Penicillium sp. (Formula I); where R 1 represents OH, C 6 H 5 COO, R 6 COO and R 6 represents...
|
|
|
7304039 |
Glucose-based compounds with affinity to P-selectin
The present invention relates to certain glucose-based compounds that have an affinity to P-selectin. Further, the invention relates to the use of these glucose-based compounds for the preparation...
|
|
|
7276228 |
Methods for treating hematological disorders through inhibition of DNA methylation and histone deacetylase
Methods are provided for treating hematological disorders by inhibition of DNA hypomethylation and histone deacetylase. Such disorders include, for example, acute promyelocytic leukemia, acute...
|
|
|
7261769 |
Stabilized anthocyanin extract from Garcinia indica
A method of making a red pigmented composition is disclosed which includes (a) preparing an aqueous extract of Garcinia indica fruit comprising at least one red colorant; (b) treating the extract...
|
|
|
7259166 |
Substituted-cycloalkyl and oxygenated-cycloalkyl glucokinase activators
2,3-Di-substituted N-heteroaromatic propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a polar ring, said propionamides being...
|
|
|
7229982 |
Pharmaceutical formulation
The instant invention provides a pharmaceutical composition comprised of a cholesterol absorption inhibitor and an HMG-CoA reductase inhibitor, one or more anti-oxidants, microcrystalline...
|
|
|
7211567 |
Composition for preventing and treating type I allergy
A food composition for preventing type I allergy, a pharmaceutical composition for preventing or treating type I allergy and an external preparation for skin for preventing or treating type I allergy.
|
|
|
7199152 |
TNF-α production inhibitor comprising kavalactone as an active ingredient
The present invention provides a TNF-α production inhibitor containing a kavalactone as an active ingredient, which inhibitor has high safety, exerts an excellent effect of inhibiting TNF-α...
|
|
|
7183315 |
Silver salts of sucrose-octasulphate
The described invention relates to the new compound “sucrose-octasulphate salified with silver” usefully applicable in the prevention and cure of infections by micro-organisms of bacterial,...
|
|
|
7157489 |
HIV protease inhibitors
Compounds useful for inhibiting HIV protease are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating wild-type HIV and of multidrug-resistant...
|
|
|
7157078 |
Devices and methods for eliminating termite colonies
This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing
a) a termiticide selected...
|
|
|
7151105 |
Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
The present invention provides compounds of formula (4), and their pharmaceutically acceptable salts and solvates, which are useful as inhibitors of the Hepatitis C virus (HCV) polymerase enzyme...
|
|
|
7148218 |
Certain substituted polyketides, pharmaceutical compositions containing them and their use in treating tumors
The present invention relates to certain substituted polyketides of formula I,
wherein A, B and C are as defined herein, pharmaceutical compositions containing said compounds, and the use of...
|
|
|
7141605 |
Method of controlling animal pests and disinfecting inanimate surfaces
A method of treating plant and animal systems and inanimate surfaces for the purposes of controlling plant pests, introducing pesticides and nutrients into plants, mitigating frost damage to...
|
|
|
7141602 |
Process for obtaining HMG-CoA reductase inhibitors of high purity
Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The...
|
|
|
7135196 |
Iron compositions
Compositions in solid form, such as powders, comprising a mixture of a ferrous salt and a hydroxypyrone maybe used to increase the level of iron in a patient's bloodstream or to treat and/or...
|
|
|
7132447 |
Substance FKI-1083 and process for producing the same
The present invention is comprised of culturing microorganism having ability to produce FKI-1083 substance represented by the formula:
in a medium, accumulating FKI-1083 substance in the...
|
|
|
7129238 |
Mandelic acid derivatives
The invention is concerned with novel mandelic acid derivatives of formula (I)
wherein R 1 to R 10 , X and Y are as defined in the description and in the claims, as well as pharmaceutically...
|
|
|
7125897 |
Combined therapies for atherosclerosis treatment
There is provided a combination treatment for slowing or arresting the progression and/or effecting the regression of atherosclerotic plaque deposits in a mammalian patient, said combination...
|
|
|
7122573 |
Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of polyphenol catechins that occur in green tea, such as epigallocatichin-3-gallate...
|
|
|
7115658 |
Inhibitors of hepatitis C virus RNA-dependent RNA polymerase
Compounds of formula I are hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp) inhibitors, and are useful in therapeutic and prophylactic treatment of persons infected with hepatitis C virus
|
|
|
7109236 |
Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
Novel compounds useful as chemotherapeutic and chemopreventive agents are provided. The compounds are analogs of polyphenol catechins that occur in green tea, such as epigallocatichin-3-gallate...
|
|
|
7109206 |
Methods and compositions for the rapid and enduring relief of inadequate myocardial function
Disclosed are methods and compositions for reducing coronary artery stenosis, restoring blood flow to infarcted myocardium, improving myocardial perfusion, reducing heart attacks or other adverse...
|
|
|
7094804 |
Water free ubiquinone concentrate
A water soluble, essentially water-free ubichinon concentrate is described, which contains an emulsifier with an HLB value between 9 and 16, ubichinon Q 10 , as well as a light oil containing...
|
|
|
7091221 |
Partial ester of cellulose with nitrogenous carboxylic acid and process for producing the same
According to the present invention, there are provided a novel partial ester of a nitrogenous carboxylic acid ester with cellulose, the partial ester being useful as an antibacterial agent, a flame...
|
|
|
7078433 |
FC101 and analogs as a method of treatment for cancer
The present invention provides a treatment for angiogenic diseases, including solid tumors. The treatment consists of administering therapeutically active dosages of FC101, resulting in a reduction...
|
|
|
7078059 |
Treatment of bone diseases
The invention provides a method for enhancing bone formation, inhibiting osteoclastic differentiation and/or activating osteoblastic differentiation whereby to manage, treat or achieve prophylaxis...
|