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4634718 |
Use of O-substituted derivatives of (+)-cyanidan-3-ol as compounds having immunomodulating properties
The present invention relates to the use of O-substituted derivatives of (+)-cyanidan-3-ol corresponding to the formula ##STR1## and their addition salts, in which R represents an optionally...
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4613505 |
Ester of flurbiprofen and emulsion containing the same
There is provided a fat emulsion of an ester of flurbiprofen having the formula ##STR1## wherein R is a group of the formula ##STR2## wherein R 1 is a hydrogen atom or a C 1 -C 3 alkyl group, R...
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4594354 |
Animal feed compositions containing the antibiotic X-537A
Compositions containing the antibiotic having the designation X-537A, useful for the treatment and prevention of coccidiosis in poultry feed compositions containing the antibiotic and methods of...
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4588713 |
Selective biologically active 7-oxo-prostacyclin derivatives and pharmaceutical compositions containing same
Compounds of the formula ##STR1## are disclosed wherein R 1 stands for hydrogen, C 1 -4 straight or branched alkyl or pharmacologically acceptable cation, R 2 stands for hydrogen, C 1 -4...
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4582853 |
Treatment of coccidiosis with antibiotic X-14934A
The present invention relates to a novel polyether ionophore antibiotic of the formula ##STR1## and its pharmaceutically acceptable salts. The compound of formula I and its salts exhibit activity...
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4578400 |
Therapeutic composition and method for treatment of cardiovascular diseases
A therapeutic agent for the treatment of cardiovascular diseases which contains as the effective component at least one compound selected from the group consisting of 5-hydroxydecanoic acid, a salt...
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4571405 |
Anti-allergic chromone- or thiochromone-5-oxamic acid derivatives, compositions, and method of use therefor
Certain 5-substituted chromones and thiochromones and pharmacologically acceptable salts thereof are disclosed. The compounds possess antiallergic properties and are represented by the formula:...
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4564620 |
5,6,7,-Trinor-4,8-inter-m-phenylene PGI.sub.2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them
Pharmaceutically useful compounds are 5,6,7-trinor-4,8-inter-m-phenylene PGI 2 derivatives such as 5,6,7-trinor-4,8-inter-m-phenylene-13,14-didehydro PGI 2 ,...
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4545982 |
Pyranone compounds and skin-lightening cosmetic preparations or local demelanizing agents containing the same
Novel acyl compounds 3-acyloxy-4(H)-pyran-4-ones were obtained by reacting 3-hydroxy-4(H)-pyran-4-one with acyl halides. The acyl compounds and their starting compound exhibit a skin-lightening...
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4544666 |
Chemotherapeutic agents for the control of plant diseases
A chemotherapeutic composition for the control of plant diseases caused by mycoplasma-like organisms, rickettsia-like organisms, or seed-borne legume viruses. The composition is composed...
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4533553 |
Polycyclic ether antibiotic
Growth of cattle and swine is promoted and feed utilization efficiency increased by an improved nutrient feed containing the antibiotic of the formula ##STR1##
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4515805 |
Soluble sodium cromoglycate compositions
There is described a mixture of sodium cromoglycate of mass median diameter from 2 to 30 microns with a pharmaceutically acceptable water soluble carrier of sieve size from 200 to 1000 microns, the...
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4489093 |
Insecticidal esters
Novel esters in all possible isomeric forms of the formula ##STR1## wherein R is selected from the group consisting of (a) optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally...
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4466969 |
7-Oxoprostacyclin derivatives and their use as hypotensives and bronchodilators
Prostacyclin, although having a useful dilating effect on blood vessels, is not sufficiently stable to ensure successful use as a hypotensive agent. A 7-oxo prostacyclin derivative of the general...
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4465689 |
Antibacterial compounds
Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
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4451481 |
M-4 And IsoM-4 derivatives and compositions containing them
Dihydro-M-4 and dihydro-IsoM-4 are new compounds which may be prepared by the catalytic hydrogenation of M-4 or IsoM-4 respectively. They, and their salts and esters (which may be prepared by...
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4447445 |
Manoalide, an anti-inflammatory analgesic marine natural product
The method of treating mammals including humans in need of a drug having analgesic and/or anti-inflammatory activity comprising the administration of a therapeutically effective amount of...
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4447421 |
Process for the preparation of medicated animal feed supplement
The invention is a process for the preparation of animal feed supplements containing various drugs or drug combinations, wherein uniformly potent particles of controlled particle size are obtained...
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4431665 |
Acylated laidlomycin derivatives
Compounds represented by the formula ##STR1## wherein R 1 is an aliphatic or alicyclic hydrocarbon acyl group of two to eighteen carbon atoms and R 2 is an alkali metal cation or hydrogen are...
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4424212 |
K-41.C(2) esters
This invention relates to K-41.C(2) esters, miticidal compositions comprising K-41.C(2) esters and anti-coccidial compositions comprising K-41.C(2) esters.
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4397847 |
Method of treatment
The present invention relates to a method of treating osteoporosis by administering to a host suffering from osteoporosis an effective amount of 24,24-difluoro-1α,25-dihydroxycholecalciferol.
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4394377 |
Ruminant animal performance by co-administering choline and propionate enchancers
The availability of supplemental dietary choline to animals with a developed rumen is increased by co-administering choline or choline compounds with a propionate-enhancing antibiotic compound.
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4391822 |
Method for preventing cats from shedding Toxoplasma oocysts after infection of such cats
A method of preventing, or at least substantially minimizing, shedding of Toxoplasma oocysts by cats is described which can be begun after infection of the cat and may serve to reduce the...
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4389410 |
Esters of monic acid A useful as antibacterial and antimycoplasmal agents
Compounds of formula (II): ##STR1## wherein R is C 1 -20 alkyl; C 3 -8 cycloalkyl; C 3 -20 alkenyl; aralkyl; cycloalkylalkyl; heterocyclyl or heterocyclylalkyl; each being substituted with formyl;...
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4374147 |
13-Oxo-monic acid esters useful as antibacterial and antimycoplasmal agents
Compounds of formula (II): ##STR1## in which R represents a pharmaceutically acceptable ester-forming radical have antibacterial and antimycoplasmal activity. These compounds are produced by...
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4369186 |
4,5-Dichloroimidazole-2-carboxylic acid derivatives
4,5-Dichloroimidazole-2-carboxylic acid derivatives of the formula ##STR1## in which the group ##STR2## represents a carbon atom which has three bonds to hetero-atoms, and their salts with bases,...
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4369174 |
Cosmetic composition containing kojic acid ester
A cosmetic composition containing a kojic acid ester with an aliphatic carboxylic acid, which is desirable for application to the skin. The kojic acid ester has an excellent effect of whitening the...
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4366168 |
Anticoccidial combinations
Combinations of a polyether antibiotic and a 2,4-dinitro-N-[4-(fluoroalkoxy)phenyl]-6-(trifluoromethyl)be
nzenamine are synergistic in controlling coccidiosis in animals.
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4364956 |
5-Substituted pyranone compounds and their use as pharmaceuticals to treat an immediate hypersensitivity condition
Compounds are described of the formula ##STR1## in which R 1 is COOR 5 , CONHR 5 , cyano, 5-tetrazolyl or 5-tetrazolylaminocarbonyl, where R 5 is hydrogen or C 1 -6 alkyl; R 2 is hydrogen or C 1...
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4351845 |
Method of increasing feed efficiency in swine
Oral administration of lasalocid to swine in the grower and finisher phases of their life cycle results in an increase in the rate of growth and in the efficiency of feed utilization.
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4351844 |
Hypocholesterolemic hydrogenation products and process of preparation
Hydrogenation of the natural fermentation product, mevinolin, MK-803, results in the production of dihydro- and tetra-hydro derivatives and hydrogenation of the naturally occurring dihydromevinolin...
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4343796 |
2,3-Bis-hydroxybenzyl-derivatives
The invention relates to compounds of the formula: ##STR1## in which R 1 and R 2 are the same or different groups selected from hydrogen or acyl or R 1 and R 2 together may represent an...
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4343814 |
Hypocholesterolemic fermentation products
Substances isolated after cultivation of a microorganism belonging to the genus Penicillium in a culture medium comprises compounds which have structures: ##STR1## Together with salts and esters of...
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4338332 |
Fluoro-prostaglandins
16-Fluro-13, 14-dehydro-PG 2 series compounds have been prepared.
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4331658 |
Method of treating swine dysentery with antibiotic A-32887
Method and compositions for treatment of swine dysentery with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.
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4312874 |
Antibacterial compounds, processes for their preparation and compositions containing them
A ketone of formula (II): ##STR1## wherein Y represents ##STR2## and R represents a C 1 -10 alkyl, C 2 -10 alkenyl, C 2 -10 alkynyl, aryl, aralkyl or cycloalkylalkyl group, optionally substituted...
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4305956 |
Miticidal method
A miticidal method comprises applying a miticidal composition comprising Lysocellin having the formula ##STR1## or its salt or ester.
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4303647 |
Method of treating coccidiosis with antibiotic A-32887K
Methods and compositions for treatment of coccidiosis in poultry with antibiotic A-32887 (K-41). Antibiotic A-32887 is produced by submerged aerobic fermentation of Streptomyces albus NRRL 11109.
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4302450 |
Polyether ionophores as antiobesity and hypotriglyceridemic agents
A method is disclosed for the use of polyether ionophores as antiobesity and hypotriglyceridemic agents in warm blooded animals by the administration to an animal in need of such treatment of a...
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4297367 |
2-Phenyl-4-pyrone derivatives, their preparation and their use as fungicides
The invention relates to new 2-phenyl-4-pyrone derivatives which can be used in agriculture. They correspond to the general formula: ##STR1## in which X 1 and X 2 , which are identical or...
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4294846 |
Hypocholesteremic fermentation products and products of preparation
Substances isolated after cultivation of a microorganism belonging to the genus Aspergillus in a culture medium comprise compounds which have structures: ##STR1## Together with salts and esters of...
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4293650 |
Anti-coccidial substance and its preparation
37,454 RP of the formula: ##STR1## and its non-toxic salts with metals and nitrogen-containing bases possess anti-coccidial activity.
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4291053 |
Agent to be administered orally to domestic animals without cellulose digestion in the rumen
Agents containing Salinomycin for oral administration to domestic animals which do not digest cellulose in the rumen, particularly pigs, are disclosed, for instance for the prophylaxis or treatment...
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4287206 |
Halogen derivatives of 8-hydroxycarboxylic acids; the processes for their preparation and medicaments in which they are present
Halogen derivatives of 8-hydroxycarboxylic acids, which correspond to the formula ##STR1## (open form, in a basic medium) or to the formula ##STR2## (cyclized form, in an acid medium) in which...
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4263273 |
Pharmaceutical preparation comprising a cardiac glycoside with a polymer coating
A solid pharmaceutical preparation for administration in dosage unit form comprising a therapeutically effective cardiac glycoside, whereby each dosage unit is to comprise a plurality of bodies,...
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4261971 |
Pharmaceutically preparation comprising a cardiac glycoside in combination with a polymer
A solid pharmaceutical preparation for administration in dosage unit form comprising a therapeutically effective cardiac glycoside, whereby each dosage unit is to comprise a plurality of bodies,...
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4262013 |
Mevalonolactone derivatives and process for the preparation thereof
This invention concerns novel mevalonolactone derivatives having the formula ##STR1## wherein A represents a direct linkage, methylene, ethylene, trimethylene or vinylene group; R 1 represents...
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4261988 |
Chromanone derivatives
Compounds useful in the treatment of cholesterolaemia are of the general formula ##STR1## or salts thereof in which R 1 and R 2 independently denote radicals including hydrogen, alkyl, aryl and...
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4260631 |
Oral administration of Salinomycin to pigs
Agents containing Salinomycin for oral administration to domestic animals which do not digest cellulose in the rumen, particularly pigs, are disclosed, for instance for the prophylactic treatment...
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4255444 |
4-Hydroxy-2-pyrone derivatives having antihyperlipaemic activity
4-Hydroxy-2-pyrone derivatives of formula (I): ##STR1## (wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or...
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