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6617361 |
Behavior chemotherapy
A protocol for prevention of Alzheimer's disease onset is described. The protocol involves stimulating the implicit memory, followed by continuing such stimulation in conjunction with psychological...
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6617349 |
Blends of isoflavones and flavones
Blends of quercetin and isoflavones from the group consisting of genestein, daidzein and glycetin display synergistic effects when applied as anti-inflammatory agent or as skin agent in particular...
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6610744 |
Methods of treatment with compounds having RARα receptor specific or selective activity
Retinoid compounds which act specifically or selectively on RAR α receptor subtypes in preference over RAR β and RAR Γ receptor subtypes, posses desirable pharmaceutical properties associated...
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6610738 |
N-disubstituted carbamoyloxy flavones
The invention relates to new flavone derivaties which have at least one N-disubstituted carbamoyloxy unit (OOCNR 6 (R 7 ))coupled directly to one or both aromatic rings of the flavone molecule.
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6608089 |
Derivatives of flavones, xanthones and coumarins
Compounds having the formula (I) Z—OCH 2 —C≡CCH 2 —NRR 1 (I) or a pharmaceutically acceptable salt or solvate thereof wherein Z can represent the formula (1A) or (1B). The compounds...
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6605639 |
Ligands of nuclear receptor
It has been newly found out that ascochlorin, which is a publicly known fat-soluble antibiotic, and its homologues serve as a ligand of retinoid X receptor and react in vivo with the amino group of...
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6602517 |
Dietary supplements for treating inflammation-related diseases
The present invention provides dietary supplements, medical foods and methods effective to ameliorate at least one of the symptoms, preferably all of the symptoms, of an inflammation-related...
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6596761 |
Cosmetic and dermatological preparation with flavonoids
The invention relates to cosmetic and dermatological formulations having a) a content of a compound or several compounds from the group consisting of flavonoids, or having b) a content of an...
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6596759 |
Medicament for treatment of irritable bowel syndrome
A medicament for preventive and/or therapeutic treatment of irritable bowel syndrome which comprises as an active ingredient a substance selected from the group consisting of an...
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6596745 |
Method for treating fibrotic diseases with azolium chroman compounds
Provided is a method of treating or ameliorating hypertension in an animal comprising administering an effective amount of a compound of formula I:
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6596758 |
Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process
The present invention relates to benzopyrans and benzoxepines of formula (I), wherein X, A, R 1 , R 2 and (R) p have the meanings as given in claim 1, which can be used in the treatment of...
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6596284 |
Treating eczema with a combination of isotonic saline ocean® and nasal mast cell stabilizers
The present invention relates to the prevention and treatment of atopic dermatitis and treatment of atopic dermatitis and other eczematous disorders by application of topical mast cell stabilizers...
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6589981 |
Tumor radiosensitization and/or chemopotentiation using isocoumarin derivatives
A method for enhancing the efficacy of chemotherapy and/or radiation in the treatment of cancer in animals, particularly humans, is provided wherein certain isocoumarin derivatives which exhibit...
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6589983 |
Benzopyran derivative
This invention relates a benzopyran denvative of formula (I) wherein, R 1 and R 2 represent each independently a hydrogen atom, a (substituted)C 1-6 alkyl group or a (substituted)phenyl group,R...
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6589962 |
Alpha-hydroxy-gamma-&lsqb &lsqb (carbocyclic-or heterocyclic-substituted)amino&rsqb carbonyl&rsqb alkanamide derivatives and uses thereof
Certain α-hydroxy-γ-[[(carbocyclic- or heterocyclic-substituted)amino]carbonyl]alkanamide derivatives are described as inhibitors of HIV protease and inhibitors of HIV replication. These...
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6586425 |
Cytoskeletal active agents for glaucoma therapy
Methods for the treatment of glaucoma are provided by the present invention. The compounds described cause a perturbation of the actin cytoskeleton in the trabecular meshwork or the modulation of...
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6586460 |
Heteroarotinoids containing urea or thiourea linker
Compounds, known as heteroarotinoids, having varying abilities to inhibit growth of certain cancerous cells, induce normal cell differentiation, and induce apoptosis or death of cancerous cells, of...
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6579902 |
Ribose-substituted aromatic amides, method for the production and use thereof as medicaments
Compounds of formula (I); wherein R 1 =alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R 2 =hydrogen or halogen; R 3 =hydrogen, alkyl or...
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6579903 |
Klainetins and their derivatives, method for their preparation and use thereof
The invention relates to compounds of formula I and of formula II in which R 1 , R 2 , R 3 , R 4 , R 5 , X 1 , X 2 , X 3 , X 4 , X 5 and Y are defined in the specification. The compounds of...
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6576660 |
Methods and compositions for regulation of 5-α-reductase activity
Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.
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6573295 |
Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediated by one or more molecular interactions involving a...
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6569416 |
Compositions containing synthetic soil-extract materials and medicaments based thereon
Compositions for treating viral and bacterial diseases are described. The compositions contain a synthetic soil phenolic polymeric material which contains sulfur, boron, alkaline earth, or...
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6569446 |
Solubilization of flavonols
A method of increasing the solubility in water of a flavonol component of a flavonol-containing composition, the method including the steps of providing a flavonol-containing composition, providing...
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6565851 |
Relieving symptoms of erectile dysfunction with proanthocyanidins
Use of proanthocyanidins as an active ingredient of a stimulator as a source of arginine and a source of nitric oxide in the treatment of erectile dysfunction. The active ingredient stimulates the...
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6565864 |
Skin care product containing retinoids and phytoestrogens in a dual compartment package
A stable skin care product containing a first composition comprising about 0.001% to about 10% of a retinoid; a second composition comprising about 0.001% to about 10% of a phytoestrogen; a first...
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6562863 |
Partially purified cocoa extracts containing cocoa polyphenols
Disclosed and claimed are cocoa extracts such as polyphenols or procyanidins, methods for preparing such extracts, as well as uses for them, especially as antineoplastic agents and antioxidants....
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6562865 |
Composition comprising a tramadol material and an anticonvulsant drug
This invention relates to a pharmaceutical composition comprising a combination of a tramadol material and an anticonvulsant drug and to the pharmacological use of the composition in treating...
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6562866 |
Method for preventing or treating elevated blood lipid level-related diseases by administering rutin and quercetin
0A method for treating or preventing an elevated blood lipid level-related disease in a mammal, which comprises administering thereto an effective amount of rutin, quercetin or a mixture thereof.
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6562864 |
Catechin multimers as therapeutic drug delivery agents
Described herein are catechin multimers, and particularly substituted catechin multimers, and their use as carrier moieties for the delivery of nucleophilic and cationic bioactive therapeutic...
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6562791 |
Glucopyranoside, process for isolation thereof, pharmaceutical composition containing same and use thereof
A novel glucopyranoside, 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-β-D-glucopyranosi
de of the formula 1 isolated from Pterocarpus marsupium and to a process for the isolation thereof is...
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6559144 |
Bicyclic amino acids
Compounds of the formula I in which X, Y, Z, R 1 , R 2 , R 3 , R 4 , R 5 , R 7 , R 8 , R 11 , m and n have the meanings stated in claim 1, and their physiologically acceptable salts can be...
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6559133 |
Use of flavone 8-acetic acid in vascular and cardiovascular interventions and acute coronary syndromes
A method for treatment of a vascular or cardiovascular condition or acute coronary syndromes comprises administering an effective amount of a flavone 8-carboxylic acid to a mammal suffering from a...
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6555571 |
3-methyl -chromane or thiochromane derivatives
The present invention relates to 3-methyl-chromane or thiochromane derivatives, pharmaceutically acceptable salts, stereoisomers or hydrates thereof, and an anti-estrogenic pharmaceutical...
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6555523 |
Use of cirsiliol and derivatives to treat infections
The invention provides the use of flavin compounds such as cirsiliol, 3′,4′-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment of infections, particularly for viral (e.g., HCV, HIV,...
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6555573 |
Method and composition for the topical treatment of diabetic neuropathy
A method and composition for the treatment of diabetic neuropathy is disclosed. The composition comprises a cold compounded mixture of a compound that promotes synthesis of nerve growth factor, an...
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6555575 |
Use of &ggr -tocopherol and its oxidative metabolite LLU-α in the treatment of disease
The present invention is generally related to the discovery of the therapeutic benefit of administering γ-tocopherol and γ-tocopherol derivatives. More specifically, the use of γ-tocopherol and...
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6552072 |
Use of metal complexes to treat gastrointestinal infections
Compositions and methods for treating gastrointestinal symptoms and gastrointestinal microbes are provided. In accordance with the method, a dietary metal and a dietary ligand are administered,...
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6552068 |
3-ethyl-, 3-propyl- or 3-butyl-chroman and thiochroman derivatives
A compound having the following general formula (1): in which R 1 represents an ethyl group, etc.; R 2 represents a hydrogen atom, etc.; R 3 represents a C 1 -C 5 perhalogenoalkyl group,...
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6551630 |
Genera Prunus endocarp dietary supplement
A dietary supplement product comprises an endocarp of the genera Prunus in ingestible form The endocarp has been lyophilized to remove hydrocyanic acid to a safely ingestible level.
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6552070 |
Health food useful for preventing liver and biliary dysfunctions containing an alkanoyl L-carnitine and Silybum marianum extract
A health food/dietary supplement is disclosed, endowed with a protective action on liver function against exogenous and endogenous hepatoxic agents, the characterizing components of which are...
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6552054 |
Chromone derivatives, process for the preparation of the same and uses thereof
The invention provides chromone derivatives of the following general formula, a process for preparing such chromone derivatives and a prophylactic and therapeutic agent comprising such chromone...
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6552069 |
3-methyl-chroman and -thiochroman derivatives
The present invention provides a compound having the following general formula (1): in which R 1 represents a hydrogen atom, etc.; R 2 represents a C 3 -C 3 perhalogenoalkyl group, etc.; each...
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6545042 |
Acellular biological material chemically treated with genipin
A method for promoting autogenous ingrowth of damaged or diseased tissue selected from a group consisting of ligaments, tendons, muscle and cartilage, the method comprising a step of surgically...
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6541510 |
Antiviral methods and compounds
The invention provides a method, compounds, and compositions for inhibiting the replication or proliferation of a virus. In accordance with the invention, at least one cannabichromene derivative is...
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6541038 |
Method for treating wood with a metal-containing treating agent and wood treated thereby
A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion...
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6538023 |
Therapeutic uses of green tea polyphenols for sickle cell disease
The method of therapeutic management of sickle cell anemia involving oral administration to the patient of an effective dose of green tea polyphenols.
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6538021 |
Method for producing luteolin and luteolin derivatives
Disclosed is a method for producing compounds of formula (I), wherein R 1 represents H or (CH 2 ) m OH, R 2 represents H or (CH 2 ) n OH, R 3 represents H or (CH 2 ) p OH and m, n and p...
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6531505 |
Immunosuppressive agents
An immunosuppressive agent which is very effective for treating autoimmune disease, inflammatory reaction, fibrosis or dysfunction caused by autoimmune disease and related disease thereof with...
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6531139 |
Self-emulsifying formulation for lipophilic compounds
The present invention provides a novel pharmaceutical composition based on the use of a particular oil phase which comprises a lipophilic, pharmaceutically active agent, a mixture of diglyceride...
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6528489 |
Mycotoxin derivatives as antimitotic agents
The present invention provides a treatment for mammalian diseases characterized by aberrant cell proliferation. The treatment consists of administering therapeutically active dosages of antibiotic...
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