|
Match
|
Document |
Document Title |
|
|
7618997 |
Diaminofluorescein derivatives
A compound represented by the following formula (I):
wherein R 1 and R 2 represent amino groups that substitute at adjacent positions on the phenyl ring, provided that either of R 1 and R 2 ...
|
|
|
7601754 |
Flavonoid compounds as therapeutic antioxidants
Novel flavonoid compounds having anti-oxidant activity are described. Formula 1. The compounds have been shown to exhibit anti-oxidative properties in biological systems and their utility in a...
|
|
|
7592328 |
Natural cyclodextrin complexes
The present invention is directed to the novel use of complexes of cyclodextrin. In particular the invention is directed to a complex of a cyclodextrin selected from the group consisting of α-CD,...
|
|
|
7589083 |
Compounds and compositions to control abnormal cell growth
A class of compounds commonly containing a trialkylammonium group have been synthesized and characterized as anticancer compounds. A representative of this class,...
|
|
|
7585985 |
Substituted benzopyrans as selective estrogen receptor-beta agonists
The present invention relates to substituted benzopyran derivatives, stereoisomers, and pharmaceutical acceptable salts thereof useful as Estrogen Receptor beta agonists for treating Estrogen...
|
|
|
7585893 |
Anti-cancer composition comprising DMXAA or related compound
The present invention relates to the use of compounds such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) for the treatment of cancer, wherein...
|
|
|
7576124 |
Anti-first-pass effect compounds
Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for their preparation and for...
|
|
|
7576123 |
Anti-first-pass effect compounds
Compositions, methods, etc. for addressing the first-pass effect.
|
|
|
7557138 |
5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel
Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects,...
|
|
|
7510830 |
Cancer treatment by combination therapy
Methods and compositions are provided for treating cancer, the methods including the step administering, either sequentially or simultaneously, (i) a compound of the xanthenone acetic acid group of...
|
|
|
7473789 |
9-(1′,5′-dimethyl-1′-vinyl -4′- hexenyl)-4-hydroxy-7H-furo[3,2-γ] [1] benzopyran-7-one as antibacterial agent
The object of the present invention is to provide an antibacterial agent which has an improved antibacterial effect and a wider antibacterial spectrum than conventional antibacterial agents, and...
|
|
|
7462642 |
Anti-cancer combinations
The present invention relates to synergistic combinations of the compounds of formula I such as compounds of the xanthenone acetic acid class such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA)...
|
|
|
7449589 |
Process for purifying (-)-Δ9-trans-tetrahydrocannabinol
A process for separating (−)-Δ 9 -trans-tetrahydrocannabinol from a mixture of cannabinoids is disclosed. The process comprises at least one chromatographic step wherein a mobile phase passes...
|
|
|
7435754 |
Laulimalide microtubule stabilizing agents
A method of inhibiting the proliferation of a hyperproliferative mammalian cell having a multiple drug resistant phenotype utilizing an amount of a laulimalide compound effective to disrupt the...
|
|
|
7423026 |
Methylated cyclodextrin complexes
The present invention is directed to novel complexes of cyclodextrin. In particular the invention is directed to a complex of a cyclodextrin selected from the group consisting of...
|
|
|
7338971 |
Treatment of inflammatory, cancer, and thrombosis disorders
This invention provides for the treatment of inflammatory, cancer and thrombotic disorders through the administration, in combination, of a COX2 inhibitor, low dose aspirin, and antioxidant...
|
|
|
7329687 |
Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents
Compounds useful as chemotherapeutic, chemopreventive, and antiangiogenic agents are provided. The compounds are flavanoids, including flavanones, flavanols, and chalcones. The compounds have the...
|
|
|
7326734 |
Treatment of bladder and urinary tract cancers
Compositions of matter and methods wherein chalcone and flavone derivatives are administered to human or veterinary patients for the treatment of bladder or urinary tract cancer. Compounds of the...
|
|
|
7317038 |
Nerve regeneration promoters containing semaphorin inhibitor as the active ingredient
To provide a semaphorin inhibitor; a peripheral or central nerve regeneration promoter which contains said semaphorin inhibitor as an active ingredient; and a preventive or remedy for a neuropathic...
|
|
|
7253207 |
Quinones as disease therapies
Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
|
|
|
7244760 |
Methods for preparation and use of psorospermin analogs
Psorospermin is a cytotoxic dihydroflranoxanthone that has found to exhibit significant activity against various tumor cell lines. Unfortunately, psorospermin is no longer readily available from...
|
|
|
7238725 |
Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
The present invention relates to novel tricyclic compounds useful for the treatment of inflammatory conditions, diseases of the central nervous and insulin resistant diabetes.
|
|
|
7208518 |
Substituted furochromene compounds of antiinflammatory action
The present invention relates to novel compounds of the formula (I)
including all stereoisomers and tautomers thereof, to the pharmaceutically acceptable salts and solvates thereof, to the...
|
|
|
7202272 |
Compound
A compound is described. In particular, a non-steroidal sulphamate compound is described. The compound is suitable for use as an inhibitor of oestrone sulphatase. The compound is of general Formula...
|
|
|
7183313 |
Keto cannabinoids with therapeutic indications
Novel tricyclic cannabinoid compounds are presented. Some of these compounds exhibit fluorescence properties. The fluorescent cannabinoid compounds are typically endogenously fluorescent. Some of...
|
|
|
7182964 |
Dissolving thin film xanthone supplement
A nutraceutical composition containing xanthones for oral ingestion is disclosed. The composition is a rapidly dissolving film comprising water soluble polymers and xanthones. The xanthones are,...
|
|
|
7115655 |
Pyranocoumarin derivatives
The present invention relates to compounds of the following formula (I) or pharmaceutically acceptable salts thereof. The present invention also relates to use for a cognitive-enhancing agent of...
|
|
|
7098188 |
Anticonvulsant derivative salts
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the...
|
|
|
7094378 |
Method and apparatus for inactivation of biological contaminants using photosensitizers
Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein,...
|
|
|
7087640 |
Substance with sedative effect
A substance with sedative effect comprises a therapeutically effective amount of a gamma-pyrone such as comenic acid, meconic acid, chelidonic acid, and alike in a pharmaceutically acceptable...
|
|
|
7074824 |
Pharmaceutical compositions containing beta-lapachone, or derivatives or analogs thereof, and methods of using same
Beta-lapachone, which is poorly soluble in most pharmaceutically acceptable solvents, has demonstrated significant antineoplastic activity against human cancer lines. The present invention...
|
|
|
7041650 |
Anticonvulsant derivative salts
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the...
|
|
|
7019024 |
Pharmaceutical for treatment of neurological and neuropsychiatric disorders
The invention provides a pharmaceutical for treatment of neurological and neuropsychiatric disorders comprising a compound of the formula:
or a pharmaceutically acceptable salt thereof.
|
|
|
7015194 |
Pharmaceutical composition comprising factor VIIa and anti-TFPI
The present invention relates to the use of factor VIIa and TFPI inhibitor in the treatment or prophylaxis of bleeding episodes or coagulative treatment.
|
|
|
6995187 |
Peripheral cannabinoid receptor (CB2) selective ligands
Novel polycyclic cannabinoid analogs are presented which have preferentially high affinities for the cannabinoid CB2 receptor sites. The improved receptor affinity makes these analogs...
|
|
|
6962931 |
Self-emulsifying formulations of cholesteryl ester transfer protein inhibitors
CETP Inhibitors have improved solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent, or a surfactant. Preferred such compositions are...
|
|
|
6960300 |
Process for preparing water soluble diterpenes and their applications
Aqueous solutions of diterpenes such as Forskolin, its congeners, analogs and derivatives, up to approximately 6% concentration, are prepared using suitably substituted cyclodextrin as a...
|
|
|
6921775 |
Methods for modulating brain damage
Methods are disclosed for modulating brain damage mediated by non-NMDA ionotropic glutamate receptor antagonists, as topiramate, in conditions such as periventricular leukomalacia, cerebral palsy,...
|
|
|
6890950 |
Lapachone delivery systems, compositions and uses related thereto
In part, the present invention is directed to a system comprising a lapachone or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable polymer, methods for treatment...
|
|
|
6887895 |
Pseudolaric acid-B derivatives, their preparation and pharmaceutical compositions
The invention relates to pseudolaric acid-B derivatives of general formula (I), wherein (a) R 1 is cyano, heterocyclyl, COXR′ or CON(R″) 2 , wherein X is O or NH, R′ is H, cycloalkyl, alkyl,...
|
|
|
6887862 |
Method for improving treatment selectivity and efficacy using intravascular photodynamic therapy
A method in which photodynamic therapy is employed to inhibit, stabilize or reduce occlusions within the cardiovascular system by utilizing light within the spectral region of approximately 390 to...
|
|
|
6875745 |
Method and composition for the treatment of cancer
We have discovered that the administration of a G1 and/or S phase drug such as β-lapachone in combination with a G2/M drug such as a taxane derivative such as paclitaxel resulted in a greater than...
|
|
|
6825226 |
Apoptosis inducing adamantyl derivatives and their usage as anti-cancer agents, especially for cervical cancers and dysplasias
The invention relates to the discovery that specific adamantyl or adamantyl group derivatives containing retinoid-related compounds induce apoptosis of cancer cells and therefore may be used for...
|
|
|
6797729 |
Therapeutic glutamine and N-actyl-cysteine composition
Compositions comprising glutamine in combination with other ingredients such as N-acetyl-cysteine are disclosed. Such compositions can be administered to treat patients with certain conditions of...
|
|
|
6790463 |
Uses of targeted oxidative therapeutic formulation in arteriosclerosis
The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction...
|
|
|
6784204 |
Antibiotic cytosporacin
This disclosure describes new antibiotic Cytosporacin having the structure: The invention relates to a new antibiotic designated Cytosporacin, to its production by fermentation, to methods for...
|
|
|
6774142 |
Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto
3-Deoxyflavonoid compounds and methods for inhibiting T-cell activity and treating diseases and disorders (e.g., autoimmune disorders, inflammatory disorders, diabetes, ALS, MS, rheumatoid...
|
|
|
6770671 |
7,8-dihydro-xanthenone-8-carboxylic acid derivative and novel microbe producing the same
Disclosed are a novel compound represented by the following chemical formula (1), useful for the prophylaxis and treatment of angiogenic diseases, its production, and a novel microorganism...
|
|
|
6740676 |
4-&lsqb (8-ETHYNYL, 8-VINYL OR 8-ETHYNYL-METHYL)-6-CHROMANOYL&rsqb -BENZOIC AND 2-&lsqb 4-&lsqb (8-ETHYNYL, 8-VINYL OR 8-ETHYNYL-METHYL)-6-CHROMANOYL&rsqb -PHENYL&rsqb -ACETIC ACID, THEIR ESTERS AND SALTS HAVING CYTOCHROME P450RAI INHIBITORY ACTIVITY
Compounds of Formula 1: wherein the variables are defined in the specification have cytochrome P450RAI-1 and P450RAI-2 inhibitory activity, and are suitable for treatment of mammals with...
|
|
|
6737439 |
Aromatase inhibitors from Broussonetia papyrifera
A composition and method of cancer treatment is disclosed. The composition and method utilized the extract of B. papyrifera , or compounds included therein having aromatase inhibition properties,...
|