Matches 201 - 250 out of 312 < 1 2 3 4 5 6 7 >
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5141953 Purpuromycin for the treatment of vaginal infections and pharmaceutical dosage forms for said use  
Use of the antibiotic purpuromycin for the topical treatment of infectious vaginitis and topical dosage forms containing said product. The antibiotic purpuromycin is simultaneously active against...
5141942 Pharmaceutical compositions comprising labdane diterpenoid derivatives and pyrimido(6,1-a)isoquinolin-4-one derivatives and their use  
Pharmaceutical compositions comprising labdane diterpenoid derivatives and pyrimido(6,1-a)-isoquinolin-4-one derivatives when administered to the skin of a mammal or of the man increase the rate of...
5139940 Activation compounds and methods of synthesis of activation compounds  
The invention is directed to isopsoralen compound compositions that contain a variety of substitutions which yet permit their binding to nucleic acid polymers. Reaction conditions that activate...
5118705 Water soluble salts of purpuromycin and pharmaceutical formulations thereof  
Water soluble salts of purpuromycin, their use for the topical treatment of infectious vaginitis and topical dosage forms containing said products. Oral and parenteral formulations for...
5118494 Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations  
Pharmaceutical suspension aerosol formulations using one or more perfluorinated carboxylic acids or esters thereof as surface-active dispersing agents and 1,1,1,2-tetra-fluorethane or...
5116864 Method for preventing restenosis following reconfiguration of body vessels  
Restenosis following vascular recanalization is prevented by administering a photoactivatable psoralen and, in conjunction with recanalization, delivering ultraviolet radiation to the region of...
5114721 Preparation of T-cell and T-cell membrane for use in prevention and treatment of autoimmune diseases  
Pharmaceutical preparations are provided for preventing or treating autoimmune diseases in which the active principle is activated T-lymphocyte cells, specific for the autoimmune disease to be...
5104894 Ellagic acid analogues  
Synthetic novel ellagic acid congeners of the formula: ##STR1## wherein: R 1 is --H, --OH or --OR'; R 2 is --H, --OH or --OR'; R 3 is --H, --OH or --OR'; R 4 is --H, --OH or --OR'; ...
5093106 Method for contrasting malignant neoplasms using fluorescein and a sugar  
The present invention is used for diagnosis, including early diagnosis, of malignant growths, for assessment as of the extent of malignant infection, for determining of the required volume for...
5093331 Labdane derivatives, a process for their preparation, and their use as medicaments  
The present invention relates to polyoxygenated labdane-derivatives of the formula ##STR1## a process for their preparation and the use of these substances as medicaments, preferably as medicaments...
5071853 Polycyclic amines useful as cerebrovascular agents  
A novel series of polycyclic amines, derivatives, methods of making the compounds, novel intermediates, compositions containing them, and methods for using them in the treatment and prevention of...
5047412 Alkene derivatives  
The invention describes novel (2-styryl-, 2-naphthyl- and 2-phenethyl-4-o-hydroxyphenyl-1,3-dioxan-5-yl)alkenoic acids and related tetrazoles and sulphonamides, of the formula I wherein Q completes...
5043350 Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives  
Benzo-fused cycloalkane and oxa- and thia- cycloalkane trans-1,2-diamine compounds of the formula: ##STR1## wherein A, B, C, D, n, X, Y, R, R 1 , R 2 and R 3 are as defined in the specification,...
5036102 Method of treating autoimmune diseases comprising administration of psoralen dosage forms  
A method of treating leukocyte mediated autoimmune and skin diseases using psoralen reagent composition comprising sterile aqueous solutions suitable for extracorporeal administration to blood from...
5032591 Pharmaceutical preparations  
A pharmaceutical product comprising a potassium channel activator antihypertensive agent and a β-blocker antihypertensive agent as a combined preparation for simultaneous, separate or sequential...
5023270 Antidepressant method of use  
This invention concerns a pharmaceutical composition useful for treating depression in humans, comprising an effective amount of 5-methoxypsoralen, and optionally, a suitable carrier or diluent,...
5017368 Composition for application to hair or scalp  
A composition for application to hair or scalp comprises (A) at least one compound selected from the group consisting of (i) forskolin and derivatives thereof and (ii) peptides having a basic...
5017603 Xanthomegnin, a known compound, is an antiparasitic agent  
The controlled aerobic fermentation of the fungal organism Fusarium lateritium var. longum produces xanthomegnin. Xanthomegnin has been discovered to have potent parasiticidal, anthelminthic, and...
4999378 Phenylcarboxylic acid derivatives  
Phenylcarboxylic acid derivatives having the formula: ##STR1## wherein R 1 and R 2 are each H, halogen, alkyl, haloalkyl, alkanoyl, cycloalkyl, nitro, amino, --O--D--R 5 (D is alkylene, R 5 is...
4999375 Psoralen reagent compositions for extracorporeal treatment of blood  
Psoralen compositions for extracorporeal administration to blood prior to reinfusion into a subject comprising a sterile aqueous solution of about 0.005 to about 1 mg/ml of a psoralen ethyl...
4987150 Agent for inhibiting binding of 5-dihydro-testosterone with androgen receptor as well as process for obtaining same  
An agent for inhibiting the binding of 5α-dihydrotestosterone with androgen receptor, which comprises at least one extract from herbs or one of specific xanthone compounds, and a process for...
4983625 Psoralene-based bath compositions for treatment of skin disorders  
A bath composition for the treatment of psoriasis or other cutaneous disorders contains from 10-79.9 weight percent of a hydrophilic phase, from 20-89.9 weight percent of a fatty or lipophilic...
4963581 Naphthopyran derivatives and use thereof  
The present invention relates to an aromatase inhibiting composition which contains a compound of the formula: ##STR1## wherein R is hydroxy, lower alkoxy or amino which may be substituted by lower...
4963537 Labdane compounds, pharmaceutical compositions and use  
Novel labdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
4939167 Use of 5-methoxypsoralen and other furocoumarins as jet lag suppressants  
Disclosed is use of 5-methoxypsoralen to prevent and suppress the symptons of jet lag.
4927849 Sulfonamido derivatives inhibiting the aldose reductase enzyme system and pharmaceutical compositions containing them  
The xanthosulfonamido and benzensulfonamido derivatives corresponding to the formula: ##STR1## wherein x represents hydrogen, alkyl, alkoxy or halogen, Y represents an alkyl, alkoxy or halogen and...
4920146 Carbamoyloxylabdane compounds useful in reducing intraocular pressure  
Novel carbamoyloxylabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure and treating cardiac failure utilizing compounds and compositions...
4913901 Pharmaceutical composition for oral administration and process for the use thereof  
An orally administrable and stable solution containing as an active ingredient Methoxasalen (8-methoxyfuro-[3',-2':6,7]-coumarin) of the formula ##STR1## useful in the photochemotherapy of...
4883793 Hydrazinocarbonyloxylabdanes for treating cardiac failure  
Novel hydrazinocarbonyloxylabdanes, intermediates and processes for the preparation thereof, and a method for treating cardiac failure utilizing compounds or compositions thereof are disclosed.
4882350 Derivatives of 1-benzyl-2-oxo-5-alkoxy-pyrrolidine, and medicament compositions containing them  
Compounds useful in the treatment of patients suffering from intellectual or nervous asthenias, memory failures, senescence or metal strain of the formula (I) ##STR1## in which R' represents...
4853410 Hydroxyacetic acid derivatives for the treatment of diabetic complications  
Racemic and chiral (2R,4R)-4-c-hydroxy-2-4-(substituted)chroman(and thiochroman)-4-acetic acids and their pharmaceutically acceptable salts, their use in the treatment of diabetic complications and...
4847290 Delta 1-thc-7-oic acid and analgesic and anti-inflammatory agents  
A non-psychoactive metabolite of THC is described. The invention is based on the discovery that this metabolite has analgesic and anti-inflammatory properties. The use of the metabolite as a...
4845121 Aci-reductone compounds belonging to the 6,7-disubstituted-3,4-dihydro benzopyan-2H-one class having antiaggregatory properties  
The present invention relates to novel benzopyranone aci-reductone compounds of the formula I wherein X and Y are selected from the group comprising H (except that X and Y are not both H, unless...
4816479 Xanthone derivatives and process for producing the same  
Xanthone derivatives of the formula (I): ##STR1## wherein W, X, Y and Z which may be the same or different represent a hydrogen atom, a halogen atom or a lower alkyl group having 1 to 4 carbon...
4782082 Method for treating allergic reactions with Forskolin  
Forskolin and its disclosed derivatives are useful as antiallergic agents. Certain of the derivatives are novel.
4772603 Method for treating congestive heart failure, angina, occlusive peripheral vascular disease or cerebral vascular disease in mammals  
A method for the treatment and/or prophylaxis of congestive heart failure, angina, occlusive peripheral vascular disease or cerebral vascular disease in mammals, such as humans, which method...
4751224 Treatment of metastasis  
A method for reducing the incidence of metastasis in tumor victims without treating the primary tumor per se resides in the administration of forskolin or its analogs which are potent inhibitors of...
4740522 Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure  
Novel oxolabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
4724238 Method of treating inflammatory diseases with labdan derivatives  
The present invention relates to a process for the isolation of labdan derivatives from the plant Coleus forskohlii, and their use as medicaments having anti-inflammatory and analgesic activity.
4670452 Dioxo dibenzopyrans and anti-allergic use thereof  
There are provided benzopyrans of formula I ##STR1## wherein R 6 and R 7 together form the chain --CHOCH(A 1 E 1 )--O-- in which --O-- is attached to R 7 , R 5 represents hydrogen, R 8...
4639446 Aminoacyllabdanes, pharmaceutical compositions and use  
Novel aminoacyllabdanes, intermediates and processes for the preparation thereof, and methods for reducing intraocular pressure utilizing compounds or compositions thereof are disclosed.
4626432 Storage of red blood cells  
Use of compounds of formula (I) ##STR1## to provide a more effective delivery of oxygen to the tissues of a mammalian, including human, recipient. In vivo applications include the relief or...
4578399 Use of the diterpene derivative forskolin for immunostimulation  
The possibility of using the diterpene derivative forskolin (1α, 6β, 9α-trihydroxy-7β-acetoxy-8,13-epoxy-14-labden-11-one) to increase the immunological responsiveness of mammals is described.
4571405 Anti-allergic chromone- or thiochromone-5-oxamic acid derivatives, compositions, and method of use therefor  
Certain 5-substituted chromones and thiochromones and pharmacologically acceptable salts thereof are disclosed. The compounds possess antiallergic properties and are represented by the formula:...
4564626 Methods of inducing bronchodilation  
A method for producing bronchodilation in a mammal is disclosed. Composition for use in said method are also described.
4556651 Secalonic acid derivatives as antitumor agents  
A secalonic acid derivative of the formula (I); ##STR1## wherein R is ##STR2## wherein R 1 and R 2 each independently is a hydrogen atom or a C 1 -4 alkyl group; R 3 is a hydrogen atom, a C 1 -4...
4476140 Composition and method for treatment of glaucoma  
Topical administration of one of the polyoxygenated Labdanes of which forskolin is an example to the eyes produces lower intraocular pressure. The topical application to the eye produces no...
4454152 Methoxsalen dosage forms  
This invention relates to oral dosage forms wherein the active ingredient, methoxsalen, is dispersed in a water-soluble composition containing a polyethylene glycol or mixtures of polyethylene...
4382952 Antibiotic roridin L-2 and its use  
The present invention relates to a novel trichothecene antibiotic, roridin L-2, and a process for the production and the method of using said compound.
4376123 Hexahydroazepinyloxy-chromones useful as antidepressants  
Basic ethers of the formula ##STR1## wherein Z is CH 3 --NR 2 --CH 2 CH 2 --CHR 1 --, (1-R 2 -3-piperidyl)-CHR 3 --, (1-R 2 -2-piperidyl)-CH 2 --CHR 3 - or 1-R 2 -3-R 4 ...
Matches 201 - 250 out of 312 < 1 2 3 4 5 6 7 >