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6239114 |
Compositions and methods for treatment of neoplastic diseases with combinations of limonoids, flavonoids and tocotrienols
Compositions and methods for the prevention and treatment of neoplastic diseases are described. Individuals at a high risk of developing or having neoplasia undergoing conventional therapies may be...
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6235773 |
Compositions for regulating skin appearance
The present invention relates to methods for preventing or treating skin disorders using flavonoid compounds. The present invention also relates to methods for regulating skin condition.
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6214867 |
Anticonvulsant derivatives useful in treating essential tremor
Anticonvulsant derivatives useful in treating essential tremor are disclosed.
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6207658 |
Preservation of tissue during removal storage and implantation
A method is provided for preserving tissues during removal, storage and implantation into a subject by enhancing cell viability in a population of graft cells during the transplantation procedure....
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6177441 |
Treating red blood cell solutions with anti-viral agents
Methods and compositions for treating pathogens in material are described, including methods of decontaminating human fluids prior to processing in the clinical laboratory and methods for...
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6177424 |
4'-Substituted-4',5'-dihydropsoralens and therapeutical uses thereof
The invention relates to 4'-substituted-4',5'-dihydropsoralen compounds of formula(V): ##STR1## In the formula R is hydrogen, a halogen, CN or an acyl group; T is a halogen, CN, a carboalkoxy group...
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6169109 |
Method of inactivation of viral and bacterial blood contaminants
Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
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6160006 |
6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor in grapefruit
The present invention provides a composition and methods for inhibiting cytochrome P450 enzyme activity and in particular, inhibiting the activity of the cytochrome P450 3A sub-family of enzymes,...
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6156723 |
Compositions comprising inhibitors of estrogen response
The present invention provides novel assay methods for identifying compounds that may have both estrogen agonist and antagonist properties. In particular, the assay use cells comprising promoters...
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6147081 |
Ophthalmic solution
A novel ophthalmic preparation containing menthol together with sodium cromoglycate and an antihistaminic is provided, which alleviates the unpleasant irritating eye-ache induced by sodium...
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6117862 |
Model and method for angiogenesis inhibition
The invention provides a method to inhibit the formation of neovasculature while maintaining viability of the underlying tissue by subjecting a subject in which angiogenesis is to be inhibited to...
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6096316 |
Composition for limiting and attenuating the visible symptoms of natural or accidental ageing of the skin
The composition is characterized in that it contains an extract of Chrysanthellum indicum with low concentration comprising 0.0001% to 0.05% of equivalent dry extract of Chrysanthellum indicum. It...
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6096740 |
Dexanabinol derivatives and their use as neuroprotective pharmaceutical compositions
The present invention relates to pharmaceutical compositions for preventing or alleviating neurotoxicity. Said pharmaceutical compositions comprise as their active ingredient the stereospecific (+)...
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6090398 |
Composition and method for the control of diabroticite insects
Diabroticite insects, in particular the corn rootworm, are major pests of corn as well as a variety of other agricultural crops. The invention describes an aqueous composition which is effective as...
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6087390 |
Derivatives of antifungal substance BE-31405 and process for producing the same
The present invention relates to a compound represented by general formula (I) or a pharmaceutically acceptable salt or ester thereof: ##STR1## wherein each of R 1 and R 2 is independently a...
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6083978 |
Compounds with a sulfamate group
A sulphamate compound suitable for use as an inhibitor of both oestrone sulphatase activity and aromatase activity. The compound can have the general formula (II) wherein F represents a phenolic...
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6071946 |
Tricyclic urea compounds
A compound selected from those of formula (I): ##STR1## in which A, Y, R 1 , R 2 and R 3 are as defined in the Specification, and pharmaceutical compositions containing the same, which are useful...
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6054449 |
Compounds and method for PDT of intimal hyperplasia and other diseases
A broad class of photosensitive compounds having enhanced in vivo target tissue selectivity and versatility in photodynamic therapy. Many furocoumarin compounds, such as psoralens, exhibit...
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6034120 |
Insect antifeedant for agriculture
The present invention provides an antifeedant and a contact insecticide using the components contained in Cyperaceae species. In particular, the present invention provides an insect antifeedant and...
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6015785 |
Aglucone isofavone enriched vegetable protein extract and isolate and process for producing
Aglucone isoflavone enriched vegetable protein extract and isolate and process for producing and recovering are disclosed. The aglucone isoflavone extract is made by extracting a vegetable protein...
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5998461 |
Tricyclic amide compounds
This invention relates to benzofuran/pyran derivatives of a new tricyclic amide compound, their composition and method of use for treating disorders of the melatoninergic system.
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5990104 |
Polycyclic alcaloid-derivatives as NMDA-receptor antagonists
Polycyclic alkaloids of formula (I), wherein R 1 is H, C 1 -6 alkyl, or C 6 -12 aryl optionally substituted with polar groups; R 2 and R 3 are independently H, OH, C 1 -6 alkyl, --C(NH)--NH 2 ,...
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5985914 |
Treatment of inflammatory disorders of the bowel and urinary bladder
A method of treating inflammatory disorders of the bowel and inflammatory disorders of the urinary bladder are disclosed. A method of modulating the function of monocytes is also disclosed. The...
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5981495 |
Benzopyran derivative and method for treating heart disease using this derivative
The present invention offers a safe and effective drug for heart diseases and a safe and effective method for treating heart diseases such as ischemic heart disease and cardiac arrhythmia. The...
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5962512 |
Oil containing 5-methoxypsoralen at a concentration of 60-100 ppm, and its use in treatment of psoriasis
The invention relates to topically applied pharmaceutical compositions containing 5-methoxypsoralen in a concentration of 60 ppm to 100 ppm, and more particularly 65 to 95 ppm, and preferably 75...
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5942539 |
Methods of treating or preventing endometriosis with phytoestrogens
Methods of using phytoestrogens, in particular, isoflavones in the prevention and treatment of endometriosis and related disease conditions in females. One method comprises administering a...
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5932221 |
Genistin-enriched fraction from soy meal
Disclosed is how to make and to use a genistin-enriched fraction from soy meal. The fraction is prepared by acetone extraction of soy meal, followed by ice-water precipitation. The resulting...
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5929108 |
Photochemical labelling of nucleic acids with digoxigenin reagents and their use in gene probe test systems
The present invention concerns photochemical labelling reagents comprising a digoxigenin derivative and a furocoumarin derivative bound via a spacer. The labelling reagent can be used in gene...
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5922709 |
Antifungal composition
An antifungal composition, containing a synergistic mixture, containing the compound of the formula (I): ##STR1## wherein R is acetyl or lower alkyl; or a pharmaceutically acceptable salt thereof;...
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5910509 |
Antimicrobial agent for agriculture
The invention provides a method of treating or preventing a fungal infection comprising administering to a plant having a fungal infection a composition comprising an effective amount of a compound...
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5902823 |
Method for treating addiction using forskolin or extracts containing forskolin
The present invention relates to the use of forskolin and of the extracts containing it for the treatment of alcohol addiction.
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5851792 |
Aglucone isoflavone enriched vegetable protein whey whey protein material aglucone isoflavone material high genistein content material and high daidzein content material and process for producing the same from a vegetable protein whey
An aglucone isoflavone enriched vegetable protein whey, whey protein material, high genistein material, high daidzein material, and aglucone isoflavone material are provided, as well as a process...
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5843990 |
Pyran-chromenone compounds, their synthesis and anti-HIV activity
The invention relates to pyran-chromenone compounds, their synthesis and anti-HIV activity. Methods of synthesis are disclosed; the compounds have activity against reverse transcriptase. Biological...
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5843988 |
Cyclopropachromencarboxylic acid derivatives
The present invention provides novel cyclopropachromen-carboxylic acid derivatives having an antagonistic activity against metabotropic glutamate receptors and its pharmaceutically acceptable...
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5843989 |
C.sub.4 -amide substituted compounds and their use as therapeutic agents
The invention provides certain 5 and/or 8 substituted benzopyran, pyranopyridine or tetrahydroquinaline compounds having C 4 -amide substituent and processes for making them. The compounds...
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5824320 |
Cosmetic or pharmaceutical compositions containing, as active ingredient, mangiferine or its derivatives, in pure form or in plant extracts
A cosmetic or pharmaceutical composition including, as the active ingredient, a compound of general formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are selected from --H,...
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5804596 |
Method of preparing a forskohlin composition from forskohlin extract and use of forskohlin for promoting lean body mass and treating mood disorders
A method of promoting lean body mass in an individual is disclosed, comprising administering to the individual a lean body mass promoting effective amount of forskohlin. A method of treating a mood...
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5789439 |
Pharmaceutical use of forskolin derivatives
The present invention relates to novel pharmaceutical use of forskolin derivatives represented by the general formula: ##STR1## wherein R 1 , R 2 and Ac are as defined later ##STR2## (wherein R 3 ...
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5770619 |
Method of activating photosensitive agents
A method of administering photodynamic therapy begins with administering to an animal an effective amount of a photosensitizing agent which is less than about one half of the usual clinical dose...
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5763479 |
Naphthoquinone derivatives for the treatment of chronic inflammation
A redox, hydrogen-acceptor compound, having utility in treating inflammation, is a 1,4-dioxonaphthalene or 1,4-dilminon aphthalene having either a 2,3-double bond, in which cast there are 2 and...
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5753693 |
Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder
This application relates to the use of topiramate and related sulfonamides for the treatment of manic-depressive bipolar disorder.
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5753694 |
Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS)
Disclosed herein is a method of treating amyotrophic lateral sclerosis with topiramate and related compounds.
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5736563 |
Transcutaneous in vivo activation of photosensitive agents in blood
A method destroys or impairs target cells that have selectively accumulated a photosensitizing agent. The target cells are in the bloodstream of an intact animal, which bloodstream and animal...
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5708012 |
Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of insulin resistant subjects with normal glucose tolerance in order to prevent or delay the onset of noninsulin-dependent mellitus
Novel methods of using thiazolidinone derivatives and related antihyperglycemic agents to treat populations exhibiting insulin resistent non-impaired glucose tolerance (IRNIGT) in order to prevent...
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5688777 |
Inhibition of C. difficile infections by indigestible oligosaccharides
The primary etiology of antibiotic-associated diarrhea (which may lead to pseudomembranous colitis) has been recognized as Clostridium difficile. It is believed that the indigenous microflora of a...
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5676959 |
Phototoxic insecticidal composition and method for controlling insect populations
A phototoxic insecticidal composition includes at least one photoactive dye present in the amount of between 0.025%-4.0% of the composition, an attractant compound and/or feeding stimulant and at...
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5672621 |
Carbonarin antiinsectan metabolites
Carbonarins A, B, C, D, E, F, G, and H have been isolated from the sclerotia of the fungus Aspergillus carbonarius. The carbonarius are effective for controlling Coleopteran and Lepidopteran...
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5672614 |
Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid amides
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and X have the meanings given, a process for the preparation...
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5665762 |
Decontaminating clinical samples
The present invention contemplates methods of decontaminating human fluids prior to processing in the clinical laboratory. The techniques handle large volumes of human serum without impairing the...
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5665760 |
Lyophilized thioxanthenone antitumor agents
Disclosed are reconstituted lyophilized formulations for the treatment of mammalian tumors comprising a thioxanthenone antitumor agent in combination with mannitol or sucrose as a stabilizer in a...
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