Patents in Class 514/455

Matches 51 - 100 out of 311

< 1 2 3 4 5 6 7 >

Match	Document	Document Title
51	6713506	Tea polyphenol esters and analogs thereof for cancer prevention and treatment Disclosed herein are ester-bond containing tea polyphenols that has a susceptibility to nucleophilic attack, their analogs and pharmaceutically acceptable salts, method for inhibiting proteasomal...
52	6696484	Method and compositions for regulation of 5-alpha reductase activity Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5α-reductase inhibitor, such as natural and synthetic flavanoids,...
53	6686388	Regulators of the hedgehog pathway, compositions and uses related thereto The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function...
54	6677135	Ret ligand (RetL) for stimulating neutral and renal growth Nucleotide and amino acid sequences are provided for compounds which promote tissue growth, as well as methods for modulating tissue growth, for imaging tissues and organs, and for treating...
55	6667337	Combination therapy for cancer This invention relates to a method of treating cancer, and particularly a method including the steps of administering to a mammal in need of such treatment, either simultaneously or sequentially,...
56	6660304	Method of treating prickly heat A novel powder composition comprised of a skin irritation reducing agent comprising 1-Carboxy-N,N,N-trimethylmethanaminium hydroxide inner salt, Scutellaria baicalensis extract, bisabolol, or...
57	6632835	Dibenzo&lsqb c&rsqb chromen-6-one derivatives as anti-cancer agents Molecules demonstrating anti-proliferative effects against epithelial cancer cell lines and endothelial cells and methods of synthesis are disclosed. The molecules are intended for use in...
58	6627653	Anticonvulsant derivatives useful for the treatment of depression Anticonvulsant derivatives useful for treating depression as monotherapy or combination therapy are disclosed.
59	6624189	Byrostatin analogues, synthetic methods and uses Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or imroved recognition domains are disclosed, including methods of preparing and...
60	6620842	Chalcones Disclosed are novel chalcone derivatives having the formula (I) The compounds possess antiproliferative activity and are useful for the manufacture of a medicament for the treatment or...
61	6620819	Anticonvulsant derivatives useful in treating psychosis The anticonvulsant derivative topiramate useful in treating dementia and/or behavioral and psychotic disturbances in dementia is disclosed.
62	6613797	Xanthone analogs for treating infectious diseases and complexation of heme and porphyrins Therapeutic compounds and compositions for the treatment of infectious diseases are disclosed. The compounds are xanthones and xanthone derivatives, such as...
63	6608103	Inhibitor for neovasculation, cell multiplication, lumen formation and FGF This invention relates to an inhibitor having inhibitory activity against neovasculation, cell multiplication, lumen formation and fibroblast growth factor which comprises β-, γ- or δ-tocotrienol.
64	6607712	Composition and methods containing an antimicrobial essential oil extended from Coleus forskohlii An essential oil composition from Coleus forskohlii is used in compositions and methods for the treatment of skin infections and in the prevention and treatment of dental caries.
65	6608089	Derivatives of flavones, xanthones and coumarins Compounds having the formula (I) Z—OCH 2 —C≡CCH 2 —NRR 1 (I) or a pharmaceutically acceptable salt or solvate thereof wherein Z can represent the formula (1A) or (1B). The compounds...
66	6596760	Antidiabetic 4-hydroxy-2-furoic acids Substituted 4-hydroxy-2-furoic acids are obtained by the fermentation of an asterriquinone, which is a natural product having a 2,5-dioxy-3,6-bis(indolyl)quinone structure. The compounds modulate...
67	6583172	Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders Anticonvulsant derivatives useful in treating chronic neurodegenerative conditions are disclosed.
68	6579901	Pharmaceutical compositions and methods for treating immune-response associated diseases of the surface and the anterior segment of the eye A pharmaceutical composition for the treatment of immune-related diseases of ocular surface and the anterior segment of the eye. More specifically, the invention relates to a composition comprising...
69	6576660	Methods and compositions for regulation of 5-α-reductase activity Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.
70	6545041	Tumor necrosis factor alpha (TNF-α) inhibiting pharmaceuticals Pharmaceutical compositions are described for preventing TNF toxicity, comprising as active ingredient the stereospecific (+) enantiomer, having (3S,4S) configuration of Δ 6 tetrahydrocannabinol...
71	6525089	Pharmaceutical composition containing decursin A pharmaceutical composition comprising decursin and its uses as a nephrotoxicity inhibitor, an antineoplastic agent, an antidiabetic agent, and as a cancer-cell differentiation induction agent are...
72	6512004	Promoters of neural regeneration The invention provides methods and compositions for promoting neural cell growth and/or regeneration. The general methods involve contacting with an activator of a cyclic nucleotide dependent...
73	6509371	Compositions containing Bergamottin for increasing the oral bioavailability of pharmaceutical agents Bergamottin, principle compound in grapefruit juice responsible for inhibition of p450 3a4, the predominant p450 enzyme in the intestine, is coadministered with a compound having low...
74	6506790	Compounds and methods This invention relates to substituted benzo[1,2-b:5,4-b′]dipyran-4-amines which are modulators, agonists or antagonists, of the CCR5 receptor. In addition, this invention relates to the treatment...
75	6506763	3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity The present invention relates to novel 3-(substituted)-2-indolinones compounds and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore...
76	6495585	Method for treating hyperproliferative tissue in a mammal A novel method for treating undesired hyperproliferative tissue in a mammal. The method includes the steps of: injecting the mammal with a photodynamic compound having a selective uptake in the...
77	6495523	Tricyclic monosaccharide derivatives useful in treating acute ischemia-induced neurodegeneration Anticonvulsant compounds of the general formula I: where X, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are as herein defined; are useful in treating acute ischemia-induced neurodegeneration, such as...
78	6492415	Use of benzopyranols to treat neurological disorders Benzopyran derivatives and analogs are disclosed as useful for the treatment and/or prophylaxis of neuralgia, trigeminal neuralgia, neuropathic pain, dental pain and cancer pain.
79	6486198	Compounds and methods for the treatment of post traumatic stress disorder The application relates to the use of topiramate and related sulfamates for the treatment and/or prophylaxis of post traumatic stress disorder (PTSD).
80	6478946	METHOD OF PRODUCING FULVIC, HUMIC, AND ULMIC ACID FOR USE AS AN ELECTROLYTE IN PRODUCING IONIZED BACTEREACIDES FROM PRECIOUS METALS AND METHOD OF PRODUCING IONIZED BACTEREACIDES FROM PRECIOUS METALS AND ORGANIC ACIDS A method of preparing organic acids (fulvic, humic, and ulmic) for use as an electrolyte for producing high ionizations of precious metals (such as silver) which entails leaching out the organic...
81	6472421	Methods for treating, preventing, and reducing the risk of the onset of alzheimer's disease using an HMG CoA reductase inhibitor Described are methods for treating, preventing, or reducing the risk of the onset of Alzheimer's disease by administering a therapeutically effective amount of an inhibitor of the enzyme...
82	6462024	Use of inhibitors of the sodium-hydrogen exchanger for the production of a medicament for decreasing undesired effects of substrates of the heart Inhibitors of the sodium-hydrogen exchanger are used for the production of a medicament for decreasing the undesired effects in human and in veterinary medicine which originate from substances...
83	6436930	Thio derivatives of sordarin as antifungal agents The present invention relates to antifungal compounds having the structural formula: and pharmaceutically acceptable salts, solvates and prodrugs thereof. The present invention further relates...
84	6426092	Powder compositions comprising a skin irritation reducing agent A novel powder composition comprised of a skin irritation reducing agent comprising 1-Carboxy-N,N,N-trimethylmethanaminium hydroxide inner salt, scutellaria baicalensis extract, bisabolol, or...
85	6420369	Anticonvulsant derivatives useful in treating dementia Anticonvulsant derivatives useful in treating dementia and/or behavioral and psychotic disturbances in dementia are disclosed.
86	6417224	Prophylactic, therapeutic agent for osteoporosis The prophylactic, therapeutic agent for osteoporosis of the invention is a combination of an indigestible oligosaccharide with phytoestrogen which inhibits bone loss. The action of inhibiting the...
87	6403571	Combination therapy for reducing the risks associated with cardiovascular disease The instant invention involves a combination therapy and pharmaceutical compositions comprised of a therapeutically effective amount of a cholesterol reducing agent such as an HMG-CoA reductase...
88	6403347	HIV integrase inhibitors Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of...
89	6403637	Methods of modulating matrix metalloproteinase activity and uses thereof Methods for inactivating matrix metalloproteinases in a vertebrate cell are disclosed. The methods comprise administering to the cell an agent which causes increased endocytosis of the matrix...
90	6399653	Ring fused dihydropyrans, process for preparation and use thereof The invention relates to compounds of the formula I in which the radicals R 1 , R 2 , R 3 and A have the meaning mentioned in the description. The invention further relates to a process for the...
91	6384073	Use of macrolide compounds for treating glaucoma Macrolide compounds, such as the FK506 Substance and its related compounds, are provided for the prevention or treatment of eye diseases, particularly glaucoma. Composition containing such...
92	6384045	Tricyclic and tetracyclic pyrones This invention provides cancer-active tricyclic and tetracyclic oxypyrones and a method of synthesizing these compounds. Preferred compounds have aryl groups at the 3-position of the oxypyrone...
93	6362220	Anticonvulsant derivatives useful in reducing blood glucose levels Anticonvulsant derivatives useful in reducing blood glucose levels are disclosed.
94	6350477	Food material containing antioxidant ingredient derived from citrus fruits A process for producing a food material having a high concentration of eriocitrin, which comprises extracting a juice, a peel and a squeezed juice refuse of a citrus fruit with a polar solvent,...
95	6323236	Use of sulfamate derivatives for treating impulse control disorders Impulse Control Disorders (ICD's) are characterized by harmful behaviors performed in response to irresistible impulses. The essential feature of an ICD is the failure to resist an impulse, drive,...
96	6319929	Suksdorfin analogs, compositions thereof, and methods for making and using thereof The present invention is directed to compounds that are analogs of the natural product suksdorfin. Compounds of the present invention include those having Formula IV: ##STR1## wherein R 20 through...
97	6284220	Noninvasive imaging of nucleic acid vectors Nucleic acid-imaging compositions and methods for noninvasive imaging of a nucleic acid introduced into somatic tissues of an animal or human are disclosed. The noninvasive imaging enables...
98	6255324	Amino-and mercurio-substituted 4',5'-dihydropsoralens and therapeutical uses thereof 5'-substituted, 4',5'-dihydropsoralen compounds (5) bearing tertiary amines (and salts thereof), quaternary ammonium moieties or organomercurial moieties are described. ##STR1## Also described are...
99	6255337	Anti-first-pass effect compounds and citrus extract First-pass effective substances derived from citrus.
100	6239169	Non-steroidal polycyclic ring sulphamate derivatives, their preparation and their use as oestrone sulphatase inhibitors A non-steroidal compound suitable for use as an inhibitor of oestrone sulphatase. The compound has a polycyclic ring structure comprising two or more rings wherein at least two of the rings mimic...

Matches 51 - 100 out of 311

< 1 2 3 4 5 6 7 >