|
Match
|
Document |
Document Title |
|
|
7622499 |
β-Benzyloxyaspartate derivatives with photosensitive groups
The present invention relates to photosensitive derivatives of optically active L-threo-β-benzyloxyaspartate or its benzene ring-substituted analogs, represented by the following formula (1) or...
|
|
|
7601754 |
Flavonoid compounds as therapeutic antioxidants
Novel flavonoid compounds having anti-oxidant activity are described. Formula 1. The compounds have been shown to exhibit anti-oxidative properties in biological systems and their utility in a...
|
|
|
7598291 |
Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In...
|
|
|
7592367 |
Compounds from Garcinia hanburyi, their use in treating cancer and method of separating epimers thereof
Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying...
|
|
|
7589232 |
Alkynyl aryl carboxamides
The present invention is related to alkynyl aryl carboxamides of Formula (I′) and use thereof for the treatment and/or prevention of an inflammatory disorder, obesity and/or metabolic disorders...
|
|
|
7585854 |
Method for treating endometriosis
A drug effective for prevention and therapy of endometriosis is disclosed. The drug for prevention and/or therapy of endometriosis according to the present invention comprises an antiallergic agent...
|
|
|
7576124 |
Anti-first-pass effect compounds
Safe, effective first-pass inhibiting compounds and citrus-derived substances are provided. Formulations containing the compounds are also provided as are methods for their preparation and for...
|
|
|
7576123 |
Anti-first-pass effect compounds
Compositions, methods, etc. for addressing the first-pass effect.
|
|
|
7572827 |
Use of angelicin and of its structural analogues for the treatment of thalassemia
The use of angelicin and its structural analogues for the preparation of a medicament for the therapeutic treatment of beta-thalassaemia is described. A structural analogue which is particularly...
|
|
|
7514107 |
Treatment of diseases involving defective gap junctional communication
This invention relates to compositions containing polyphenols, for example, cocoa polyphenols such as flavanols and their related oligomers, and methods for treating abnormalities in gap junctional...
|
|
|
7510830 |
Cancer treatment by combination therapy
Methods and compositions are provided for treating cancer, the methods including the step administering, either sequentially or simultaneously, (i) a compound of the xanthenone acetic acid group of...
|
|
|
7495111 |
Compounds useful as serotonin inhibitors and 5-HT1A agonists and antagonists
3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT 1A receptor (agonizing or...
|
|
|
7495026 |
Neo-tanshinlactone and analogs as potent and selective anti-breast cancer agents
Compounds of Formulas I-II are described,
along with methods of using such compounds for the treatment of cancer and pharmeutical formulations thereof.
|
|
|
7446229 |
Bicyclic cannabinoids
Bicyclic-cannabinoids and methods of preparation and use are presented. These compounds, when administered in a therapeutically effective amount to an individual or animal, results in a...
|
|
|
7399783 |
Methods for the treatment of scar tissue
A topical composition and method for the reduction of scar tissue and/or improving the appearance of scar tissue after it has formed. The topical composition includes one or more flavonoids...
|
|
|
7396828 |
PI-3 kinase inhibitor prodrugs
The invention provides prodrugs of inhibitors of PI-3 kinase. The compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.
|
|
|
7384975 |
Substituted furochromenes, preparation thereof and their antiinflammatory action
The invention relates to novel compounds of the formula (I)
including all their tautomers, to pharmaceutically acceptable salts and solvates thereof, to processes and reactive intermediates for...
|
|
|
7368474 |
Radiofluorination methods
The present invention relates to methods and reagents for [ 18 F]-fluorination, particularly of peptides. The resultant 18 F-labelled compounds are useful as radiopharmaceuticals, specifically for...
|
|
|
7329654 |
Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
The present invention is directed to novel heteroatom containing tetracyclic derivatives, pharmaceutical compositions containing them, their use in the treatment and/or prevention of disorders...
|
|
|
7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
|
|
|
7306789 |
Method of stimulating hair growth using benzopyrans
The present invention is directed to methods of stimulating hair growth by administering particular benzopyran compounds.
|
|
|
7253206 |
Phenalenone derivatives, processes for preparation and use thereof
The present invention provides novel phenalenone derivatives of formula (I) which are formed by the microorganism Penicillium herquei Bainer & Sartory, DSM 14142, during fermentation. A...
|
|
|
7208518 |
Substituted furochromene compounds of antiinflammatory action
The present invention relates to novel compounds of the formula (I)
including all stereoisomers and tautomers thereof, to the pharmaceutically acceptable salts and solvates thereof, to the...
|
|
|
7196108 |
Bicyclic heterocycles for the treatment of diabetes and other diseases
The invention relates to certain bicyclic heterocycles havng the structure shown below which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2...
|
|
|
7182964 |
Dissolving thin film xanthone supplement
A nutraceutical composition containing xanthones for oral ingestion is disclosed. The composition is a rapidly dissolving film comprising water soluble polymers and xanthones. The xanthones are,...
|
|
|
7157492 |
Dibenzo chromene derivatives and their use as ERβ selective ligands
This invention provides estrogen receptor modulators of formula I, having the structure
where R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 are as defined in the specification.
|
|
|
7157421 |
Piracetam and piracetam analog conjugate and a pharmaceutical composition for treatment of neuronal disorders
A compound of the formula
where R 1 is H, C 1 –C 4 alkyl and OH; R 2 in is H, C 1 –C 4 alkyl and OH; R 3 is H and C 1 –C 4 alkyl; R 4 is H and C 1 –C 4 alkyl; n is an integer...
|
|
|
7141605 |
Method of controlling animal pests and disinfecting inanimate surfaces
A method of treating plant and animal systems and inanimate surfaces for the purposes of controlling plant pests, introducing pesticides and nutrients into plants, mitigating frost damage to...
|
|
|
7138428 |
Compounds isolated from gamboge resin having activity in inhibiting the growth of tumor/cancer cells and pharmaceutical compositions comprising the same
Disclosed herein are an acetone-extracted product obtained from gamboge resin and compounds further purified from said acetone-extracted product, including a new compound called formoxanthone A....
|
|
|
7138427 |
5-β-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed
|
|
|
7125542 |
Methods and compositions for treating conditions of the eye
Provided are methods and compositions for the photodynamic therapy (PDT) of ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example, neovascular...
|
|
|
7108870 |
Process for isolation of withaferin-A from plant materials and products therefrom
The present invention relates to an improved process of analytical and quantitative isolation of withaferin-A from Withania somnifera (Sanskrit: Ashwagandha, English: winter cherry) and other...
|
|
|
7094802 |
PKB-3564 substance with neovascularization inhibitory activity
A compound represented by formula (I) wherein R 1 represents hydrogen atom and R 2 represents hydroxyl group, or R 1 and R 2 may combine together to represent oxo group or oxime group; R 3 ...
|
|
|
7084176 |
N-arylphenylacetamide derivatives and medicinal compositions containing the same
N-Arylphenylacetamide derivatives represented by the following formula [I]:
(wherein R 1 is C 1-6 alkoxy, etc.; R 2 is hydrogen, —(CH 2 ) m —N(R 6 )(R 7 ) (m is an integer of from 1 to...
|
|
|
7081475 |
Wortmannin analogs and methods of using same
Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well as tumor formation in a subject are described herein.
|
|
|
7074823 |
Fluorescent probe for zinc
A compound represented by general formula (IA) or a salt thereof useful as a fluorescent probe for zinc: wherein R 1 and R 2 represent a hydrogen atom or a group represented by formula (A),...
|
|
|
7019026 |
Modulators of Protein Tyrosine Phosphatases (PTPases)
Disclosed are novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds of Formula 1 are pharmacologically useful inhibitors of Protein...
|
|
|
7015244 |
Inhalable chemical debridement for COPD
Sesquiterpene epoxide compounds (trichothecenes) and methods for administering such compounds by inhalation for chemical debridement of cells in the lungs of COPD patients are disclosed.
|
|
|
7012091 |
Inhalable inhibitors of inflammation in the respiratory tract
Sesquiterpene epoxide compounds (trichothecenes) and methods for administering such compounds by inhalation to inhibit inflammatory responses in the respiratory tract are disclosed.
|
|
|
7011856 |
Composition for the treatment of symptoms and conditions associated with aging
A composition including an extract of buckwheat seed and a fractionation product of the extract of buckwheat seed useful for the prevention and therapy of aging is disclosed. The composition...
|
|
|
6974814 |
Neuropharmacological treatment of sleep-related breathing disorders
The present invention relates to pharmacological methods for the prevention or amelioration of sleep-related breathing disorders via administration of agents or combinations of agents that possess...
|
|
|
6972298 |
Method of treating or inhibiting neutrophil chemotaxis by administering a MEK inhibitor
The present invention provides a method of treating or preventing neutrophil chemotaxis. Specifically, the present invention provides a method of treating or preventing neutrophil migration by...
|
|
|
6949561 |
Steroid 3-O-sulphamate derivatives as inhibitors of oestrone sulphatase
A sulphamate compound suitable for use as an inhibitor of oestrone sulphatese (E.C.3.1.6.2) is described. The compound is a polycyclic compound comprising at least two ring components, wherein the...
|
|
|
6939860 |
Composition and method for treatment of neoplastic diseases associated with elevated matrix metalloproteinase activities using catechin compounds
The present invention relates to a composition comprising a catechin compound, ascorbic acid, proline and lysine. The present invention also relates to a method for treating neoplastic disease...
|
|
|
6939859 |
Skin preparations for external use
An dermatological agent for external use is disclosed which contains a chromanol glycoside represented by the following general formula (1)
(wherein R 1 , R 2 , R 3 , and R 4 which may be the...
|
|
|
6924306 |
Method for treating ocular hypertension
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions related to elevated intraoccular pressure in the...
|
|
|
6908902 |
Treatment of neurological dysfunction comprising fructopyranose sulfamates and erythropoietin
Co-therapy for the treatment of neurological dysfunctions comprising administration of one or more fructopyranose sulfamates and erythropoietin.
|
|
|
6908630 |
Combinations of sesquiterpene lactones and ditepene triepoxide lactones for synergistic inhibition of cyclooxygenase-2
A novel formulation is provided that serves to inhibit the inflammatory response in animals. The formulation comprises, as a first component an effective amount of a diterpene triepoxide lactone...
|
|
|
6906099 |
Treatment of addiction and addiction-related behavior using a composition of topiramate
The present invention relates to the use of a composition that increases central nervous system GABA levels in a mammal, for the treatment of addiction to drugs of abuse and modification of...
|
|
|
6905715 |
Cocoa solids having a high cocoa procyanidin content
The present invention is directed to a method of processing a fat-containing bean, e.g., cocoa beans, for producing solids comprising active polyphenols and/or fat-containing products, comprising...
|