|
Match
|
Document |
Document Title |
|
|
6168808 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic...
|
|
|
6162825 |
High fructose insecticide bait compositions
This invention relates to the discovery that in many strains of the German cockroach [Blattella, germanica (L.)], feeding is inhibited by high glucose levels, while conversely, feeding of this...
|
|
|
6159932 |
Endoparasiticidal compositions
The present invention relates to mixtures of avermectins, 22,23-dihydroavermectins B 1 (ivermectins) and milbemycins from the class of the macrocyclic lactones in combination with cyclic...
|
|
|
6160005 |
Medicament for circadian rhythm sleep disorder
A preventive and/or therapeutic medicament for circadian rhythm sleep disorders such as jet lag syndrome which comprises as an active ingredient an alkylenedioxybenzene derivative represented by...
|
|
|
6160004 |
C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
The present invention provides a two-step procedure for the replacement of the pyranose anomeric 10-OH group in dihydroartemisinin by a variety of carbon nucleophiles, resulting in the novel C-10...
|
|
|
6156751 |
Certain tricyclic substituted diazabicyclo (3.2.1) octane derivatives
This invention encompasses compounds of the formula: ##STR1## where either R 1 or R 2 represents ##STR2## and the other represents hydrogen or straight or branched chain lower alkyl having 1-6...
|
|
|
6136847 |
Water-soluble trioxanes as potent and safe antimalarial agents
Biologically-active, water soluble, 3-substituted trioxanes of the formula ##STR1## wherein R represents a COOH-- substituted aryl group, a substituted or unsubstituted heteroaryl group or an alkyl...
|
|
|
6127405 |
Method for the use of alpha arteether as an anti-bacterial and anti-fungal agent
The present invention relates to use α-arteether as a antibacterial agent, preferably for gyr mutant bacteria which are resistant to quinolone drugs and can be used as therapeutic agents for...
|
|
|
6121274 |
Dihydrobenzofurane
The invention concerns componuds of formula (I), in which R1, R2, R3 and R4 have the meanings given in the description. The compounds are novel, effective PDE-inhibitors.
|
|
|
6117854 |
Enhanced performance insecticide compositions containing plant derived oil carriers and methods of using the same
A composition effective for the control of insects is disclosed, wherein the composition contains a phenyl pyrazole compound, a halopyridyl compound, or an avermectin compound, or combinations...
|
|
|
6114376 |
Methods for using macrocyclic lactone compounds as multidrug resistance reversing agents in tumor and other cells
This invention describes methods for increasing the toxicity of a cytostatic hydrophobic chemotherapeutic agent against resistant tumor cells in mammals which comprise administering a multidrug...
|
|
|
6110716 |
HIV integrase inhibitors
Natural products such as certain chaetochromins are described. These compounds are useful in the inhibition of HIV integrase, the prevention or treatment of infection by HIV and the treatment of...
|
|
|
6100293 |
Tetracyclic triterpene derivatives with immunosuppressant activity
The compounds of Formula I ##STR1## are useful as immunosuppressive agents.
|
|
|
6096738 |
Method for treatment of headache
A method for preventing and treating headache pain comprising administering a tricyclic antidepressant compound locally to the nasal mucosa to a patient suffering from headaches.
|
|
|
6090845 |
Thromboxane ligands
A method of treating ocular hypotension, hypertension, hemorrhage, myocardial ischemia, angina pectoris, coronary contraction, cerebrovascular contraction after subarachnoidal hemorrhage, and...
|
|
|
6075035 |
Crystal of hydrate and process for preparation thereof
Dihydrate crystal of 3-[4-(8-fluoro-5,11-dihydrobenz[b]oxepino[4,3-b]pyridin-11-y
lidene)piperid ino]propionic acid providing high-intensity diffraction peaks at diffraction angles (2θ) of about...
|
|
|
6060506 |
Benzopyran derivatives as melatonergic agents
Novel derivatives of benzopyran are provided which are useful as melatonergic agents.
|
|
|
6054448 |
2-amino-2-(3-substituted cyclobutyl) acetic acid derivatives
Compounds of the formula ##STR1## in which R 1 is Y or Y--C 1 -6 alkyl, where Y is carboxy, tetrazolyl, --SO 2 H, --SO 3 H, --OSO 3 H, --CONHOH, or --P(OH)OR', --PO(OH)OR', --OP(OH)OR' or...
|
|
|
RE36481 |
HMG-CoA reductase inhibitors
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) and...
|
|
|
6004997 |
Trioxane dimer compounds having antiproliferative and antitumor activities
Novel trioxane dimers of structure ##STR1## which possess antiproliferative and antitumor activities.
|
|
|
5998408 |
Triterpene derivatives with immunosuppressant activity
The compounds of Formula I ##STR1## are useful as immunosuppressive agents.
|
|
|
5998467 |
Medicine for oculopathy
This invention is aimed at providing a novel medicine for oculopathy, which has as an active component thereof a 5-HT 1A receptor ligand such as, for example, an alkylene dioxybenzene derivative...
|
|
|
5990104 |
Polycyclic alcaloid-derivatives as NMDA-receptor antagonists
Polycyclic alkaloids of formula (I), wherein R 1 is H, C 1 -6 alkyl, or C 6 -12 aryl optionally substituted with polar groups; R 2 and R 3 are independently H, OH, C 1 -6 alkyl, --C(NH)--NH 2 ,...
|
|
|
5981571 |
Benzodioxa alkylene ethers as melatonergic agents
Novel derivatives of benzodioxa alkylene ethers are provided which are useful as melatonergic agents.
|
|
|
5981547 |
Homochroman derivatives and related compounds useful as anti-inflammatory agents
A compound having the structure: ##STR1## wherein (a) n is from about 1 to about 3; (b) X is selected from the group consisting of O, S, SO, or SO 2 ; (c) Y is independently hydrogen or straight,...
|
|
|
5977166 |
Enhanced flavors using menthone ketals
A method is disclosed for enhancing flavors in low moisture consumable items, including chewing gum, using menthone ketals. Chewing gum, oral compositions, pharmaceuticals, and low moisture foods...
|
|
|
5977165 |
Radicicol derivatives
The present invention relates to radicicol derivatives represented by the following formula (I) or pharmacologically acceptable salts thereof: ##STR1## wherein R 1 and R 2 are the same or...
|
|
|
5972994 |
Microbial transformation products with antifungal properties
Biotransformation products of a fermentation with Streptomyces sp., (Merck Culture Collection MA7165) ATCC No. 55946 are potent antifungal agents. These products may be useful in the treatment of...
|
|
|
5965604 |
Chrolactomycin compound
The present invention relates to chrolactomycin compound represented by the following formula (I): ##STR1## or pharmaceutically acceptable salts thereof having antibacterial and antitumor activities.
|
|
|
5965603 |
Nonaqueous compositions for parenteral administration
The present invention provides nonaqueous compositions comprising a saccharide fatty acid ester and an active compound. The nonaqueous compositions of this invention may be parenterally...
|
|
|
5962510 |
Antifungal composition
An aqueous composition is disclosed which comprises 0.1 to 20 g/l of polyene fungicide, 0.5 to 50 g/l of a suitable thickener and optionally 20 to 250 g/l of salt.
|
|
|
5962511 |
Drugs for allergic and eosinophilic diseases
A method of inhibiting human IL-5 gene transcriptions mRNA expression and protein production by human T-cells using one or more compounds selected from those shown by formula I shown below (where R...
|
|
|
5952334 |
Carbocyclic compounds
A compound of formula ##STR1## wherein Z is a tetrahydro-pyrano group selected from ##STR2## having antifungal activity in combination with other antifungal agents.
|
|
|
5948817 |
Polycyclic ethyl alkylamide melatonergic agents
Novel polycyclic ethyl alkylamides of formula I are active as melatonergic agents. ##STR1## wherein Z=CH (when a double bond is present) or (CH 2 ) n , wherein n is 1-4; X=O, CH 2 , or CH (when...
|
|
|
5948770 |
Antifungal macrolides and their synthesis
There are disclosed novel antifungal macrolides of the formula ##STR1## compositions containing said compounds, methods of using said compounds and a method for synthesizing the compounds.
|
|
|
5948812 |
1,7-dioxacycloalkan-8-one compounds
Disclosed are odorant compounds having 14- to 17-membered 4-methyl substituted 1,7-dioxacycloalkan-8-ones and 14- to 16-membered 1,7-dioxacycloalkan-8-ones with 4,4-dimethyl substitution. Also...
|
|
|
5932196 |
Buffered emulsion compositions containing actives subject to acid or base hydrolysis
The present invention are for emulsion compositions and the process for making such compositions containing biological and cosmetic actives subject to hydrolysis of actives during processing and...
|
|
|
5932591 |
C.sub.3 substituted trioxanes useful as antiparasitic drugs
Novel biologically-active 3-substituted trioxanes of the formula ##STR1## wherein R represents a substituted alkyl or aryl group of 1-20, preferably 1-12, carbon atoms, and methods for the use of...
|
|
|
5929114 |
Arylthio compounds
Arylthiol and dithiobisarylamide antibacterial and antiviral agents have the general formula ##STR1## where A is monocyclic or bicyclic aryl which can contain up to 3 heteroatoms selected from O,...
|
|
|
5919756 |
Amides
The present invention is directed to amides of antibiotic A82846B (also known as chloroorienticin A), and of N 4 -derivatives of A82846B. The present amide compounds are useful as antibacterials,...
|
|
|
5891906 |
Polyacetate-derived phorboids having anti-inflammatory and other uses
Compositions having anti-inflammatory, antiviral and other activities are disclosed. The compositions are derived from phorboids of the polyacetate- and bryostatin-classes.
|
|
|
5883120 |
Antifungal activity of the spongistatins
This invention relates generally to the field of antifungal agents and a pharmaceutical preparation containing those agents which appear to be potentially useful in the field of antifungal therapy....
|
|
|
5883080 |
Antiparastic auermectin derivatives
Antiparasitic avermectin derivatives of formula (I), where the broken line represents an optional bond, R 1 and R 4 are independently H, OH, halo, oximino, or an organic radical, R 2 , R 6 and R...
|
|
|
5861429 |
13-substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests
Compounds of formula (I): ##STR1## wherein: R 1 is methyl, ethyl, isopropyl or sec-butyl; X is carbonyl or methylene; Z is C(R 2 ) 2 or C(CH 2 ) m , in which R 2 is alkyl, and m is...
|
|
|
5856332 |
Composition and method of treating depression using a pentacyclic nucleus opioid antagonist in combination with a tricyclic antidepressant
A new composition and method for treating depression is claimed comprising administering to a patient exhibiting said illness or illnesses a pharmacologically effective dose of an opioid antagonist...
|
|
|
5856351 |
Artemisinin dimer compounds having anticancer activity
Novel artemisinin dimers of structure ##STR1## which possess anticancer activity.
|
|
|
5840704 |
Antiparasitic agents and process for their preparation
The invention provides novel compounds having the formula: ##STR1## wherein R when taken individually is H; R 1 when taken individually is H or OH; R and R 1 when taken together represent a...
|
|
|
5830875 |
24-and 25-substituted avermectin and milbemycin derivatives
Novel avermectin and milbemycin derivatives are disclosed, where the C-24 and C-25 carbon atoms are substituted by hydrogen, alkyl, alkenyl, substituted alkyl or substituted alkenyl groups. These...
|
|
|
5824653 |
Anthelmintic compositions for equidae
The Invention relates to an anthelmintic composition for oral use comprising an effective amount of praziquantel and an effective amount of at least one anthelmintic agent selected from...
|
|
|
5824674 |
Brefeldin A derivatives and their utility in the treatment of cancer
Provided are brefeldin A derivatives of the formula: ##STR1## wherein one of R 1 and R 2 is H and the other of R 1 and R 2 is a substituent group having 1 to 12 carbon atoms containing a basic...
|