Patents in Class 514/430

Matches 1 - 50 out of 100

1 2 >

Match	Document	Document Title
1	7612107	Treatment and inhibition of disease conditions using flexible heteroarotinoids The present invention contemplates methods of treating, reducing, inhibiting or preventing several diseases by the administration of flexible heteroarotinoids. Among the diseases or conditions...
2	7538138	Amines as histamine-3 receptor ligands and their therapeutic applications Compounds of formula (I) or a pharmaceutically acceptable salts or prodrug thereof which are useful for the modulation of the histamine-3 receptors in mammals and which are useful for the...
3	7507817	Prostaglandin prodrugs Novel compounds, and therapeutic methods, compositions and medicament related thereto are disclosed herein.
4	7495111	Compounds useful as serotonin inhibitors and 5-HT_1Aagonists and antagonists 3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HT 1A receptor (agonizing or...
5	7482472	Substituted isoindoles and their use The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and...
6	7468437	Phenyl pyrrolidine ether tachykinin receptor antagonists The present invention is directed to certain phenyl pyrrolidine ether compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular...
7	7459567	Substituted thienyl and furyl acylguanidines and methods of their use as beta-secretase modulators The present invention provides a substituted thienyl or furyl acylguanidine compound of formula I The present invention also provides methods for the inhibition of β-secretase (BACE) and for...
8	7452914	Spiro-benzo[c]chromene derivatives useful as modulators of the estrogen receptors The present invention is directed to novel spiro-benzo[C]chromene derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders mediated by one or more...
9	7439372	Therapeutic compounds A compound having a structure is disclosed herein. Compositions, medicaments, and therapeutic methods related thereto are also disclosed.
10	7378399	Avermectins substituted in the 4″ and 4′-positions having pesticidal properties What is described are a compound of the formula (I) Wherein A-B is —CH═CH— or —CH 2 —CH 2 —; n is 0 or 1; R 1 , is C 1 -C 12 alkyl, C 3 -C 8 cycloalkyl or C 2 -C 12 alkenyl; R 2 and R...
11	7351734	Aminoindane derivatives as serotonin and norepinephrine uptake inhibitors The present invention relates to aminoindane derivatives having the formula I wherein X, Y, U, R 1-2 , R 13-16 and R are as defined in the claims, or an acid addition salt thereof. The compounds...
12	7338976	Heterocyclic esters or amides for vision and memory disorders This invention relates to pharmaceutical compositions and methods for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance using heterocyclic...
13	7250157	Dermatological compositions and methods Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin...
14	7226938	Heterocyclic compounds Certain thienopyrrolyl and furanopyrrolyl compounds are disclosed as useful to treat or prevent disorders and conditions mediated by the histamine H 4 receptor, including allergic rhinitis.
15	7214701	Active substance combinations having insecticidal and acaricdal properties The invention relates to insecticidal mixtures for protecting plants against attack by pests comprising (a) compounds of the formula (I) in which W, X, Y, Z, A, B, D and G...
16	7144917	Inhibitors of matrix metalloproteinases The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune...
17	7109233	Protease inhibitors This invention relates in general to certain substituted substituted 1,1,4-1l 6 -trioxo[1,2]thiazepan-4-ylamides of formula I as defined herein which are protease inhibitors.
18	7078400	20-HETE synthase inhibitor The present invention relates to an inhibitor for production of 20-hydroxyeicosatetraenoic acid, comprising, as an effective ingredient, specific hydroxyformamidine derivatives or...
19	7078403	Antiviral agents Disclosed herein are compounds of formula II: wherein Alk, Z, X 1 , X 2 , R 1 , —R 10 and R 11 are defined herein, and their salts and pharmaceutically acceptable derivatives thereof, as...
20	7074780	Substituted phenylcyclohexanecarboxamides and their use The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the...
21	7045514	Therapeutic heterocyclic compounds Provided herein is a compound having the formula (I): Wherein said compounds are useful for the treatment of psychiatric disorders including but not limited to depression, generalized anxiety,...
22	7008903	Pesticide The present invention provides a composition comprising synergistic amounts of a compound of the formula (I) wherein X, E, R, A and Z are as defined herein, and at least one fungicidal active...
23	6992101	N-(indole-2-carbonyl) and H-thieno[2,3-b]pyrrole-5-carboxamide anti-diabetic agents The present invention provides compounds of formula (I) the prodrugs thereof, and the pharmaceutically acceptable salts of the compounds and prodrugs, wherein R′, R″, R′″, and Z are as...
24	6864254	Inhibitor for 20-hete-yielding enzyme An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is...
25	6815439	Substituted aza-oxindole derivatives Substituted aza-oxindole derivatives useful as cyclin dependent kinase II inhibitors, for preventing/reducing the severity of epithelial cytotoxicity side-effects (e.g., alopecia, plantar-palmar...
26	6703415	Inhibitors of matrix metallaproteinases The invention provides compounds that inhibit MMPs; methods for treating or preventing cancer, angiogenesis, arthritis, connective tissue disease, cardiovascular disease, inflammation or autoimmune...
27	6677367	HIV protease inhibitors based on amino acid derivatives A compound selected from the group consisting of a compound of formula I a compound of formula II and when the compound of formula I and II comprises an amino group pharmaceutically acceptable...
28	6548524	Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors This invention provides, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stromelysins and collagenases) and TNF-α converting enzyme (TACE. tumor necrosis factor-α...
29	6469048	α-pyrones for treating α-pyrone responsive states Novel α-pyrones are described. The α-pyrones are useful in a method for controlling α-pyrone responsive states in a mammal. The method includes administering to a mammal a therapeutically...
30	6444709	Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or...
31	6444230	Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid,...
32	6399052	Treating hair by targeting enzymes The invention provides the use of a hair benefit agent as an ingredient in a topical hair treatment composition for the purpose of targeting an active endogenous hair fiber enzyme when the...
33	6355671	SULFONATED DERIVATIVES OF CYCLIC PHENOL SULFIDES, PROCESS FOR THE PREPARATION THEREOF, SEPARATING AND RECOVERING AGENTS CONTAINING CYCLIC PHENOL SULFIDES, METHODS FOR SEPARATION AND RECOVERY THEREWITH, AND DRUG COMPOSITIONS CONTAINING THE SULFIDES A sulfonic acid compound of a cyclic phenol sulfide represented by formula (1): (wherein X represents a hydrogen atom, a hydrocarbon group, or an acyl group; M represents a hydrogen atom, an...
34	6350775	3-phenyl-furan-(5H)-2-one and dihydrofuran-2-one derivatives as antibacterial agents A compound of formula (I): wherein R 1 is hydroxy or of the formula —NHC(═O)(1-4C)alkyl or —NHS(O) n (1-4C)alkyl wherein n is 0, 1 or 2; R 2 and R 3 are independently hydrogen or...
35	6344485	Method for treating glaucoma Methods of using prostaglandin agonists for the reduction of intraocular pressure, and accordingly glaucoma.
36	6313160	Substituted heterocyclic compounds, method for preparing and compositions containing same The invention relates to compounds of formula (I): ##STR1## wherein: R 1 , R 2 and R 3 are as defined in the description, X is as defined in the description, Y represents an oxygen atom,...
37	6294570	Endosulfan microcapsule dispersion Aqueous endosulfan microcapsule dispersions in which the dispersed microcapsules comprise endosulfan, an organic solvent or solvent mixture and a capsule-forming material based on isocyanate...
38	6262105	Method of enhancing hair growth Methods and compositions for stimulating the growth of hair are disclosed containing prostaglandins, derivatives or analogues thereof for use in treating the skin or scalp of a human or non-human...
39	6251940	Inflammatory cell inhibitors Compounds of general formula (I) ##STR1## wherein R 4 is an ester or thioester group and R, R 1 , R 2 , and R 3 are as specified in the description, inhibit monocyte and/or macrophage and/or...
40	6221377	Administration media for analgesic, anti-inflammatory and anti-pyretic drugs containing nitrous oxide and pharmaceutical compositions containing such media and drugs Administration mediums comprising solutions of nitrous oxide in water, alcohols, ethers or oils, and optionally including essential fatty acids or C 1 -C 6 alkyl esters thereof enhance the action...
41	6168808	Synergistic composition of peracetic acid and amine oxide Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic...
42	6166028	Diaminopuridine-containing thiourea inhibitors of herpes viruses Compounds of the formula ##STR1## are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus,...
43	6124277	Antithrombotic agents This invention relates to peptide derivatives, pharmaceutical formulations containing those compound and methods of their use as thrombin inhibitors.
44	6107345	Benzocyclobutane compounds A compound of formula (I): ##STR1## wherein: Z 1 , Z 2 , Z 3 , Z 4 , which may be identical or different, represent a group as defined in the description, X represents oxygen, S(O) p , --(CH 2 )...
45	6015808	Synthesis of pharmaceutical compositions with lactams and β-lactams/oxo thia azabicyclo compounds Pharmaceutical compositions with heretofore unknown and enhanced physical, chemical, and biological properties are prepared by combining known biologically active parent compounds with oxo thia...
46	5990104	Polycyclic alcaloid-derivatives as NMDA-receptor antagonists Polycyclic alkaloids of formula (I), wherein R 1 is H, C 1 -6 alkyl, or C 6 -12 aryl optionally substituted with polar groups; R 2 and R 3 are independently H, OH, C 1 -6 alkyl, --C(NH)--NH 2 ,...
47	5977077	Xanthone analogs for the treatment of infectious diseases Therapeutic compositions for the treatment of infectious diseases are disclosed. These compositions comprise xanthones and xanthone derivatives, such as 2,3,4,5,6-pentahydroxyxanthone. Also...
48	5968478	N- methyl piperazine compounds having dopamine receptor affinity Described herein are D4 receptor-selective compounds of the general formula: ##STR1## wherein X 1 is selected from CH 2 , NH, O and S; X 2 -- is selected from CH=, CH 2 --, and N=; R 1 to...
49	5952334	Carbocyclic compounds A compound of formula ##STR1## wherein Z is a tetrahydro-pyrano group selected from ##STR2## having antifungal activity in combination with other antifungal agents.
50	5922753	Methods for treating bone deficit conditions with benzothiazole Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or "linker" defined as including a covalent bond per se so as to space the aromatic...

Matches 1 - 50 out of 100

1 2 >