Matches 551 - 600 out of 628 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >
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4330551 Therapeutic method  
Disclosed are therapeutic compositions that comprise an aqueous emulsion constituted by a pharmacologically acceptable cationic surfactant, a pharmacologically acceptable non-ionic surfactant, and...
4323568 Pharmaceutically active (omega-aminoalkoxy)bibenzyls  
(Omega-aminoalkoxy)bibenzyls are prepared and found useful as pharmaceutical agents, particularly as inhibitors of platelet aggregation.
4321271 Heterocyclic and aliphatic growth promotors  
Compounds of formula (I) ##STR1## wherein: R 1 is C 1 -6 alkyl or C 5 -7 cycloalkyl; R 2 is hydrogen or C 1 -6 alkyl; or NR 1 R 2 represents a heterocyclic ring having 5 to 7 ring atoms...
4309433 Pyridinecarbonamido-oxy or thio loweralkyl-1-(diloweralkylaminoloweralkyl)benzene and derivatives thereof, compositions containing same and method of using same  
An aminoalkylbenzene derivative of the formula: ##STR1## [wherein A is oxygen or sulfur; Y is oxo, thioxo, or cyanoimino; a is an integer of 1 to 3; b is an integer of 0 to 3; c is an...
4305940 Benzamides with local anaesthetic and antiarrhythmic activity, salts, and method of preparation thereof and pharmaceutical compositions therefrom  
Benzamides of formula I ##STR1## are described, in which R=CH 3 , Cl or COOCH 3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH 2 R'...
4304780 Aminoalkylthiophene derivatives as histamine H.sub.2 -antagonists  
The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, N-oxides, hydrates and bioprecursors thereof, in which Y represents O, S, CHNO...
4303673 N-Propionylsarcosineanilides, process for their preparation, and pharmaceutical compositions containing them  
The invention provides N-propionylsarcosineanilides of the formula: ##STR1## wherein n is an integer of 1 to about 3 and the substituent A which can be the same or different when n is greater than...
4294829 Powdery pharmaceutical composition and powdery preparation for application to the nasal mucosa, and method for administration thereof  
A powdery pharmaceutical composition and a powdery preparation in unit dosage form for application to the mucosa of the nasal cavity, at least about 90% of which consists of particles having an...
4293557 Antiulcer phenoxypropylamine derivatives  
Phenoxypropylamine derivatives of the general formula ##STR1## wherein R 1 represents a hydrogen atom or a methyl or ethyl group, R 2 and R 3 , independently from each other, represent a lower...
4279918 2-(Nuclearly-substituted)benzylpyrrolidines  
2-Benzylpyrrolidines bearing from 1 to 4 nuclear substituents on the benzyl ring are pharmacologically active, particularly on the CNS, on blood pressure and on pain sensation for warm-blooded...
4277473 4-Homoisotwistane-aminoacid amides  
Compounds having the formula ##STR1## wherein a is 0 or 1, R 1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R 2 and R 3 , which can be the same or different, are...
4277471 1,1-Biphenyl-2-yl alkylamines, formulations and antiarrhythmic treatment  
Biphenylylalkylamines which have anti-arrhythmic activity have been prepared. Pharmaceutical formulations containing such compounds and a method of treating cardiac arrhythmias are provided.
4272536 Novel tricycloundecane aminoacid amide  
A compound having the formula ##STR1## wherein a is 0 or 1, R 1 is hydrogen or lower alkyl, A is lower alkylene or lower alkylidene, and R 2 and R 3 , which can be the same or different, are...
4263316 N-(1-Methyl-2-pyrrolidinylmethyl)-2,3-dimethoxy-5-methylsulfamoyl benzamide and its derivatives, methods of preparing them and their application to the treatment of troubles of the lower part of the body  
The present invention relates to a novel veratramide, N-(1-methyl-2-pyrroinyl-methyl)-2,3-dimethoxy-5-methylsulpha moyl benzamide, its pharmacologically acceptable acid addition salts, its...
4263293 Heterocyclic containing amides as inhibitors of mammalian collagenase  
Mammalian collagenase is inhibited by compounds having the formula ##STR1## wherein R 1 is hydrogen, alkanoyl of 2 to 10 carbon atoms or arylcarbonyl; R 2 is 1-pyrrolidinyl, 1-piperidinyl,...
4252804 Therapeutically useful 3,4,5-trimethoxybenzene derivatives  
Compounds of the formula I ##STR1## wherein m and n are 0, 1 or 2, X represents oxygen, imino, benzylimino, or morpholinoethylimino, Y represents CO, CONH, COO or SO 2 , and NR 1 R 2 represents a...
4248884 2-Pyrrolidine methanol derivatives utilizable as medicaments  
The compounds of the formula: ##STR1## in which X is a hydrogen or halogen atom or an alkoxy group having 1 to 4 carbon atoms, an alkyl or cycloalkyl group having 1 to 8 carbon atoms, and R...
4242348 Novel basic substituted-alkylidenamino-oxylalkyl-carboxylic-acid esters  
Novel substituted-alkylidene-aminooxyalkylcarboxylic acid esters of the formula I and their acid addition salts have a strong antiinflammatory and a potent analgetic activity and a low toxicity....
4235896 Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same  
Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X 4 and X 5 are hydrogen or lower alkyl,...
4234602 Naphthalenone derivatives and analogs  
Compounds having the formula ##STR1## wherein R 1 is hydrogen, alkyl or aryl; R 2 is alkylamino, dialkylamino, or a nitrogen containing heterocyclic group; R 3 is hydrogen, halogen, alkyl,...
4233298 Esters of p-carbonylphenoxy-isobutyric acids  
This invention is concerned with esters of p-carbonylphenoxy-isobutyric acids of the general formulae: ##STR1## wherein R is a phenyl group substituted by one or two halogen atoms; R' is H, CH 3...
4232037 2,6-Dialkoxybenzamides, intermediates, pharamaceutical compositions and methods for treatment of psychotic disorders  
A compound of the formula ##STR1## wherein R 1 is an alkyl group with 1-3 carbon atoms, R 2 and R 3 are the same or different and each is hydrogen, chlorine or bromine; and pharmaceutically...
4225611 Novel n-substituted benzenesulfonamide, process for its preparation and medicaments containing it  
Amino-4 chloro-5 methoxy-2 N-(N-ethyl methyl-2 pyrrolidino) benzenesulfonamide is a novel compound corresponding to the formula ##STR1## and is prepared by reacting sulfonyl chloride of the formula...
4225608 Phenoxy heterocyclic amines and use thereof  
Phenoxyalkylamines of the formula Ar--O--R wherein Ar is phenyl or phenyl which is monosubstituted or disubstituted by F, Cl, Br, alkyl or alkoxy each of 1-4 carbon atoms, cycloalkoxy of 3-6...
4211776 N-Substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them  
The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which n is 2 or 3, R 1 and R 2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the...
4206117 Pyridinyl aminoalkyl ethers  
New pyridinyl aminoalkyl ethers, their N-oxides and their physiologically acceptable addition salts with acids, processes for their preparation and pharmaceutical formulations which contain these...
4199589 N-(2-Aminocycloheptyl)acylanilides and methods to treat depression  
N-(2-aminocycloheptyl)-N-alkanoylanilides and their 2-N-oxides of the formula ##STR1## e.g., trans-3,4-dichloro-N-[2-(dimethylamino)cycloheptyl]acrylanil ide, and their pharmacologically acceptable...
4198424 Substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols, their synthesis, their use and their compositions  
Selected substituted 1-phenyl-2-pyrrolidin-2-yl-ethanols and their pharmacologically-acceptable acid-addition salts are useful as analgesics in human and veterinary medicine. Such compounds are...
4192883 Amides of pyrrolidinoethylamine which can be used in lung therapy  
New chemical compounds, which are pyrrolidinoethylamine amides, in the form of free bases and salts thereof, which are useful as antitussives, pharmaceutical compositions thereof, and method of...
4189495 2-Methoxy-benzamide derivatives  
The invention provides novel 2-methoxy-benzamide derivatives of the formula: ##STR1## in which n is 1 or 2; R 1 represents a cycloalkyl-alkyl radical of formula: ##STR2## a phenylalkyl radical of...
4173640 Hypotensive perhydro naphthalene pentol derivatives  
Compounds are provided having the structure ##STR1## wherein R 1 , R 2 , R 3 or R 4 is hydrogen or acyl and R 5 is hydrogen or acyl, X is a straight or branched bivalent alkylene radical and Y...
4170653 Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers  
Disclosed herein are compounds of the formula ##STR1## in which Ar is phenyl or 1-naphthyl; R 1 is hydrogen or lower alkyl; and R 2 and R 3 together with the nitrogen atom to which they are...
4169149 Use of α-mercapto-β-arylacrylic acid derivatives in heavy metal poisoning  
This invention relates to a novel method for combatting poisoning resulting from heavy metals which comprises administering a compound of the formula: ##STR1## wherein Z is CC, O, S, NH; R is...
4161529 Phenoxy phenyl pyrrolidine compounds, compositions and methods of use  
Pyrrolidone derivatives of the formula: ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl, And Y is hydrogen, saturated or unsaturated hydrocarbon radical up...
4160030 N-oxy and N-amino guanidines  
The compounds are N-oxy and N-amino guanidines which are histamine H 2 -antagonists. A compound of this invention is N-hydroxy-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio )ethyl]guanidi ne.
4157398 N-(2-Aminocyclopentyl)acylanilides and treating depression  
N-(2-Aminocyclopentyl)N-alkanoylanilides and their 2-N-oxides of the formula ##STR1## e.g., trans-3,4-dichloro-N-[2-(dimethylamino)cyclopentyl]propionan ilide, and their pharmacologically...
4144348 Medical preparation for treatment of alcoholism  
A composition for the treatment of alcoholism, comprising as the active ingredient: ω-(3'-phenylpyrrolidyl-1')-6-propionyl benzo-1,4-dioxan hydrochloride of the following formula ##STR1## AND A...
4140770 Benzoylethers and processes for their production  
Processes for preparing benzoylethers, their acid additive salts and their quaternary ammonium salts are disclosed. These compounds have useful pharmacodynamic properties.
4132786 N-Substituted 2-methoxybenzenesulphonamides and medicaments containing them  
The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which N IS 2 OR 3, R 1 and R 2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the...
4123545 N-Propyl-3(β-hydroxyethyl)-3-(meta-hydroxyphenyl)-pyrrolidine  
The present invention provides a compound of the formula ##STR1## which possesses pharmacological activity, for example anti-psychotic activity.
4122199 Amides of pyrrolidinoethylamine which can be used in treatment of coughs  
New chemical compounds, which are pyrrolidinoethylamine amides, in the form of free bases and salts thereof, which are useful as antitussives, pharmaceutical compositions thereof, and method of...
4118499 Anti-anxiety and anti-parkinsonian 1-aminoalkyl-2-endo-chloro-7,7-dimethylnorbornanes  
1-Aminoethyl, 1-aminopropyl and 1-aminobutyl derivatives of 7,7-dimethylnorbornane are described. The amino groups are optionally substituted, for example by alkyl groups, or may be saturated...
4094976 Anticoccidial cyclicamino ethanols and esters thereof  
Novel anticoccidial poultry compositions comprising an anticoccidially effective amount of a compound of the formula: ##STR1## wherein n is 3, 4 or 5 and R is hydrogen or an acyl radical derived...
4092423 Alkoxy anilides and pharmaceutical compositions  
This invention relates to ortho-alkoxy anilines having the amino group substituted with an amino lower alkyl carboxylic residue, as well as their physiologically-compatible acid-addition salts and...
4070485 Alkoxy anilides process for preparing the same and pharmaceutical compositions  
This invention relates to ortho-alkoxy anilines having the amino group substituted with an amino lower alkyl carboxylic residue, as well as their physiologically-compatible acid-addition salts and...
4065584 Sulphur containing arylamine derivatives  
The invention provides new compounds of the formula: Ar--SO Y --Alk--NR 1 R 2 in which Ar represents a phenyl group, a phenyl group substituted by one or more C 1 -C 4 alkyl, CF 3 and COOH...
4060609 Biphenylyl ethers and method of use  
Biphenylyl ethers of the formula R--O--CH 2 --CR 1 (OH)--CH 2 Z wherein R 1 is H or CH 3 ; Z is dialkylamino of 2-8 carbon atoms, morpholino, pyrrolidino, piperidino, homopiperidino,...
4059702 3,8-Bis-basic ethers of 6H-dibenzo[b,d]pyran-6-one  
Bis-basic ethers of 9-sustituted phenanthrene and related 10-oxa and 10-aza derivatives, their method of preparation and their use as pharmaceutical agents for the prevention and inhibition of...
4038400 Method of treating conditions of delayed hypersensitivity using bis-basic substituted acenaphthene derivatives  
Novel 3,6-bis basic ketone derivatives of acenaphthene useful in treating conditions of delayed hypersensitivity are disclosed.
4027037 N-substituted β-aminocrotonic acid esters  
N-substituted β-aminocrotonic acid esters of the formula ##STR1## in which R 1 is hydrogen, or alkyl or alkenyl with up to 4 carbon atoms; R 2 is straight-chain or branched alkyl or alkenyl...
Matches 551 - 600 out of 628 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >