Matches 501 - 550 out of 616 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >
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4698345 Quinoline derivatives and their use as anti-asthmatic agents  
There are provided benzopyrans of formula I, ##STR1## wherein the substituents, R 5 -R 8 and EA are as defined in the specification. These compounds are useful as anti-asthmatic agents.
4695571 Tricyclic oxindole antiinflammatory agents  
Tricyclic oxindole carboxamides, prepared by (a) reaction of an isocyanate with the basic ring system or (b) ammonolysis of a corresponding alkyl ester, are non-steroidal antiinflammatory agents...
4680411 Pyrano[2,3-g]indoles useful as anti-ulcerous, anti-inflammatory and antalgic agent  
The present invention relates as new industrial product to a derivative of pyrano-indole chosen from the group constituted by: (i) the pyrano[2,3-g]indoles of general formula: ##STR1## in which:...
H000303 Glycoside-containing agricultural treatment composition  
This invention describes a composition of matter and a method of treating agricultural substrates in which an active ingredient selected from the group consisting of fungicides, bactericides,...
4677132 Inhibition of bone resorption by etodolac  
A method for modifying the balance between bone production and bone resorption in a host animal by administration of etodolac to inhibit bone resorption.
4638008 Antiarrhythmic agents  
This invention provides a group of antiarrythmic agents of the formula: ##STR1## in which R 1 is --CO 2 H, --CO 2 (CH 2 ) n --NR 4 R 5 , --CONR 6 R 7 , --NHCO 2 R 8 or --NHCO 2 (CH 2 ) o ...
4634705 Adrenergic amidines  
Disclosed herein are adrenergic compounds represented by the formula ##STR1## wherein m is 0, 1 or 2; R 1 , R 2 , R 3 and R 7 are taken from the group consisting of hydrogen, hydroxy, loweralkyl,...
4616028 Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives, compositions and use  
Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives and methods for their preparation and use are disclosed. The compounds are useful analgesic and antiinflammatory agents.
4614739 Oxindole derivatives, pharmaceutical compositions and use  
Oxindole derivatives of the general formula I ##STR1## are described, and also processes for their preparation and drugs containing them. The new compounds exhibit a neuroanabolic action in various...
4584312 Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid, compositions and use  
Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives and methods for their preparation and use are disclosed. The compounds are useful analgesic and antiinflammatory agents.
4578397 Indeno(1,2-b)pyrrole derivatives  
Indeno[1,2-b]pyrrole derivatives of the formula: ##STR1## wherein R 1 is hydrogen, lower alkyl or carbamoylmethyl, R 2 is halogen or trifluoromethyl, R 3 is hydrogen or halogen, and X is oxygen...
4569942 N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents  
Certain 2-oxindole-1-carboxamide compounds having an acyl substituent at the 3-position, and also further substituted on the carboxamide nitrogen by an alkyl, cycloalkyl, phenyl or substituted...
4562195 Reversing amnesia with saturated tricyclic nitrogen-containing diones  
A class of novel saturated, fused-ring, tricyclic, nitrogen-containing diones are useful as agents in treating electro-convulsive shock-induced amnesia. A method of preparing the compounds,...
4560688 Tricyclic antihistamines  
Antihistamines of the formula ##STR1## wherein ##STR2## is a 5 or 6 membered ring which is phenyl or heterocyclic; ##STR3## is a six membered ring which is 2,3, or 4 pyridyl or is phenyl or...
4558043 Heterocyclicamino containing benzofurans and 2,3-dihydrobenzofurans, compositions and use  
Benzofurans or 2,3-dihydrobenzofurans of the formula ##STR1## in which R 1 represents hydrogen or an aliphatic radical, R 2 represents an amino group disubstituted by a bivalent aliphatic...
4556672 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents  
Certain new 2-oxindole-1-carboxamide compounds having an acyl substituent at the 3-position are inhibitors of the cyclooxygenase (CO) and lipoxygenase (LO) enzymes, and are useful as analgesic and...
4546107 1,4-Methano-2-benzazepine derivatives useful as cerebal dysfunction-improving drugs, anti-convulsant, anti-epileptic or anti-anxiety drugs  
1,4-Methano-2,3,4,5-tetrahydro-1H-2-benzazepin-3-one derivatives of the formula: ##STR1## wherein X is halogen, n is 1 or 2, and R is hydrogen, lower alkyl or phenyl-lower alkyl. They are useful as...
4542147 Perfluoro-1-azatricyclic amine compound  
A novel compound of the formula, ##STR1## wherein k is zero or an integer of 1 to 2, j is an integer of from 1 to 3, l and m are each zero or an integer of from 1 to 3, and n is an integer of from...
4535085 Perfluorotricyclic amines as oxygen carriers  
A perfluorotricyclic amine compound which is usable as an oxygen carrier in an artificial blood, represented by the general formula ##STR1## wherein R denotes a perfluoroalkyl group having 1-4...
4533551 Method of treating arthritis with etodolac  
The effect of prolonged treatment with etodolac on the articular pathology associated with adjuvant arthritis in the rat has been compared to the effects produced by similar treatment with naproxen...
4529736 3a-(substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals  
This disclosure describes 3a-(substituted-phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl) octahydro]-4,7-alkano-1H-isoindoles which possess activity as antidepressants and as antistress...
4513003 Process for protecting wood using N-(dichlorofluoromethylthio)-3,6-endomethylene-Δ.sup.4 -tetrahydrophthalimide  
The novel N-(dichlorofluoromethylthio)-3,6-endomethylene-Δ 4 -tetrahydrophthalimides can be prepared from 3,6-endomethylene-Δ 4 -tetrahydrophthalimide with dichlorofluoromethanesulphenyl...
4510157 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives  
Herein is disclosed compounds of the formula ##STR1## in which R 1 ,R 2 ,R 3 ,R 4 and R 5 each is hydrogen or lower alkyl, therapeutically acceptable acid addition salts thereof, processes for...
4503067 Carbazolyl-(4)-oxypropanolamine compounds and therapeutic compositions  
Carbazolyl-(4)-oxypropanolamine compounds of the formula ##STR1## wherein R 1 is hydrogen, lower alkanoyl or aroyl; R 2 is hydrogen, lower alkyl or arylalkyl; R 3 is hydrogen or lower...
4496579 Benzodioxinopyrrole derivatives and processes for their preparation  
Compounds are disclosed of general formula ##STR1## where R is H, C 1 -6 alkyl optionally substituted by C 3 -7 cycloalkyl, C 3 -6 alkenyl or alkynyl, C 3 -7 cycloalkyl, aralkyl or --CHO and the...
4494547 2H-isoindolediones, their synthesis and use as radiosensitizers  
Isoindoledione compounds of the formula: ##STR1## wherein: R 1 and R 3 each separately is phenyl, substituted phenyl, alkyl of 1 to 4 carbons, --CHO, --CH 2 OR 6 , --CO 2 R 6 , --COR 6 ,...
4459305 Cyclopropanecarboxylic acid ester derivatives, a method of manufacturing them, and their uses  
The present invention relates to a cyclopropanecarboxylic acid ester derivative of the general formula I: ##STR1## in which R 1 stands for a hydrogen atom, a methyl group, a halogen atom or a...
4457940 Carboxylic acid ester derivatives, process for manufacturing said derivatives, insecticides and acaricides containing said derivatives, and method for killing insects and acarina by treating therewith  
Novel carboxylic acid ester derivatives, of the formula (I): ##STR1## process for manufacturing said derivatives, insecticides and acaricides containing said derivatives, and a method for killing...
4454150 6,7,8,9-Tetrahydro-3H-benz(e)indol-7-amines and a method of dopamine receptor stimulation therewith  
Herein is disclosed compounds of the formula ##STR1## in which R 1 , R 2 , R 3 , R 4 and R 5 each is hydrogen or lower alkyl, therapeutically acceptable acid addition salts thereof, processes for...
4438128 Cardioactive aryloxypropanolamines  
The present invention provides aryloxypropanolamines of the general formula: ##STR1## wherein R 1 , R 2 , R 3 and R 4 , which may be the same or different, are hydrogen or halogen atoms or lower...
4436746 Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles  
Various 1-carboxylic acid substituted-2-(1-imidazolyl)indoles and functional derivatives thereof are highly specific thromboxane synthetase inhibitors. Synthesis of, pharmaceutical compositions...
4418038 Disinfecting with chlorine-containing biocide dispensed from shaped polymeric body  
Devices for dispensing a chlorine biocide. The devices disclosed are (a) a device comprising a polymer containing a chlorine donating reagent and chlorine accepting reagent that on their release...
4385056 Benzo[4,5]pyrano[2,3c]pyrroles and pharmaceutical preparations containing same  
Benzo[4,5]pyrano[2,3c]pyrrole derivatives of the general formula: ##STR1## or pharmaceutically acceptable acid addition salts thereof, in which R 1 and R 2 represent hydrogen, alkyl, alkoxy,...
4385063 Thieno [3'2':5,6]cyclohepta [1,2-b]pyrrole derivatives  
A compound of formula (I): ##STR1## wherein: R is C 1 -4 alkyl; R 1 is hydrogen or C 1 -4 alkyl; one of A and B is sulphur, and the other of A and B is carbon doubly bound to the carbon...
4374849 6-Amidocyclonocardicins  
Disclosed are 6-amidocyclonocardicins (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics ##STR1## wherein: R is NH 2 , R 1 NH, R 1 is acyl. Also disclosed...
4374848 6-(1-Hydroxyethyl)cyclonocardicin  
Disclosed are 6-(1-hydroxyethyl)cyclonocardicins (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics. ##STR1## Also disclosed are processes for the...
4370341 6,7,8,9-Tetrahydro-3H-benz[E]indol-8-amine derivatives  
Herein is disclosed compounds of the formula ##STR1## in which R 1 ,R 2 ,R 3 ,R 4 and R 5 each is hydrogen or lower alkyl, therapeutically acceptable acid addition salts thereof, processes for...
4369188 2-Thioxobenz[cd]indole-1(2H)-acetic acid derivatives  
Herein are disclosed compounds of the formula ##STR1## in which R 1 is hydrogen, lower alkyl or --(CH 2 ) m --NR 4 R 5 wherein m is an integer from 2 to 6 and R 4 and R 5 each is hydrogen or...
4362738 Esters and amides containing the 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetyl moiety  
Compounds of the formula ##STR1## wherein each X, which may be identical or different from the other X, is oxygen or imino; R 1 is hydrogen, fluorine, chlorine or bromine; R 2 and R 3 ,...
4351842 N-Cyclopropylisoindolines  
Compounds of the general formula: ##STR1## in which A is a benzene ring or a carbocyclic aromatic group consisting of two or three fused benzene rings, the group A being linked to the nitrogen...
4343812 Antidepressant 2-amino-and-2-(substituted amino)-cis-hexahydro-carbazoles, compositions and use  
2-Amino- and 2-(substituted amino)-tetrahydro- and -cis-hexahydro-carbazoles useful for alleviating depression in mammals or as intermediate compounds thereto.
4343811 2[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indol-5-yloxy]-2-methyl propanoic acid and hyperlipidemic or atheosclerotic use thereof  
This invention relates to novel indole derivatives of formula ##STR1## and the non-toxic, pharmacologically acceptable salts thereof. These compounds exhibit desirable pharmacological properties,...
4335135 5 Amino-3,4,5,6 tetrahydro-1H-[-6-]cyclohept[c,d]indolols and a method for their use as hypotensives  
Novel trans cyclohept[c,d]indolols of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and optionally substituted aralkyl of 7 to 12...
4320129 Pyromellitic diimide complexes  
Complexes of pyromellitic diimide compounds which are ruminant feed additives and which improve feed efficiency are disclosed. The pyromellitic diimide compounds may be unsubstituted pyromellitic...
4292323 Phenyl-1,2,3,4-tetrahydrocarbazoles and use thereof  
This application relates to phenyl-substituted 1,2,3,4-tetrahydrocarbazoles and to their use as anti-depressant agents useful in the treatment of mental depression of either endogenous or reactive...
4289784 Pyromellitic diimides and method of increasing feed efficiency in ruminant animals  
Novel substituted pyromellitic diimides are disclosed wherein the compounds are assymetrically substituted with a variety of substituent groups. Processes for the preparation of such compounds are...
4288452 1-Aryloxy-3-nitratoalkylamino-2-propanols and use as β-receptor blocker  
Compounds of the formula Ar--O--CH 2 --CHOH--CH 2 --NH--R wherein Ar is phenyl; phenyl monosubstituted or polysubstituted by halogen, cyano, acylamino (in which the acyl group has 1-7 carbon...
4278667 Method of treating tardive dyskinesia by oral dosage form of a physostigmine compound  
This invention relates to the use of a physostigmine compound in oral dosage form for the relief, cure or remission of tardive dyskinesia in living animal bodies. The physostigmine compounds...
4278679 Combination of two or more drugs in a single dosage form wherein one of the drugs is a physostigmine compound  
This invention relates to the combination of a physostigmine compound, including physostigmine, physostigmine salicylate, physostigmine sulfite, physostigmine sulfate and other esters and salts of...
4258043 Pyrazino-carbazoles, process for the production thereof and pharmaceutical agents  
The present invention relates to new, pharmacologically-valuable antidepressants, which are 2,4,5,6-tetrahydro-1H-pyrazino-[3,2,1-jk]-carbazoles substituted in the 8-position and having the formula...
Matches 501 - 550 out of 616 < 1 2 3 4 5 6 7 8 9 10 11 12 13 >