Patents in Class 514/409

Matches 1 - 50 out of 265

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Match	Document	Document Title
1	8153623	Compounds Compounds of formula (I), pharmaceutical compositions thereof, and methods for treatment using the same.
2	8143193	Active agents combination exhibiting insecticidal and acaricide properties The novel active compound combinations of cyclic ketoenols of the formula (I) and the active compounds of the formula (II) listed in the description have very good insecticidal and acaricidal...
3	8138119	Alkoxyalkyl spirocyclic tetramic acids and tetronic acids The invention relates to novel alkoxyalkyl spirocyclic tetramic and tetronic acids of the formula (I), in whichA, B, D, Q1, Q2, Q3, Q4, G, W, X, Y and Z are as defined above,to a plurality of...
4	8105979	Active ingredient combinations with insecticidal and acaricidal properties The present invention relates to novel active compound combinations comprising at least one known compound from the class of the tetronic or tetramic acids and at least one further known active...
5	8106087	Spiro-oxindole compounds and their uses as therapeutic agents This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer...
6	8088815	Spiroindolinone pyrrolidines There are provided compounds of the formula wherein X, Y and R1 to R8 are described herein along with the enantiomers, pharmaceutically acceptable salts and esters thereof. The compounds are useful...
7	8058288	Amido compounds and their use as pharmaceuticals The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The ...
8	8044085	Active agent combinations with insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in which the...
9	8039503	Lapachone compounds and methods of use thereof The present invention provides novel tricyclic spiro-oxathiine naphthoquinone derivatives, a synthetic method for making the derivatives, and the use of the derivatives to induce cell death and/or...
10	7998959	Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of ...
11	7994208	Crystalline chemotherapeutic N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N′-(2-fluoro-5-methy lphenyl)urea·¼ Ethanolate Crystalline Form 1, ways to make it, formulations comprising it and made with it and methods of treating pat...
12	7968585	Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention ...
13	7968107	Oil-based suspension concentrates New, oil-based suspension concentrates composed of at least one room-temperature-solid active agrochemical substance,at least one “closed” penetrant,at least one vegetable oil or mineral oil,at lea...
14	7960404	Spirocyclic cyclohexane compounds Spirocyclic cyclohexane compounds corresponding to formula I in which R1 and R2 form a pyrrolidine ring or an azetidine ring and which exhibit increased metabolic stability, a process for producing...
15	7947704	2,4,6-phenyl-substituted cyclic ketoenols The invention relates to novel 2,4,6-phenyl-substituted cyclic ketoenols of the formula (I), in which CKE, W, X and Y are as defined above,to a plurality of processes and intermediates for their...
16	7943605	Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses The present invention relates to compounds of formula (I) comprising a lactam or a lactam derivative moiety, processes for preparing them, pharmaceutical compositions comprising said compounds and...
17	7935721	Spiro-oxindole compounds and their uses as therapeutic agents This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer...
18	7915282	C2-phenyl-substituted cyclic keto-enols used as pesticides and herbicides The present invention relates to novel C2-phenyl-substituted cyclic ketoenols of the formula (I) in which W, X, Y, Z and CKE are as defined in the description, to processes for their preparation...
19	7829535	Methods for bone treatment by modulating an arachidonic acid metabolic or signaling pathway Methods for promoting osteogenesis to accelerate or enhance bone fracture healing, treat bone defects, and enhance bone formation are disclosed. The methods modulate an arachidonic acid metabolic...
20	7825152	Organic compounds and their uses The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
21	7803833	Compounds The invention relates to quaternary α-aminocarboxyamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, X, q and n are as defined in claim 1, for treating diseases and conditions ...
22	7781449	Trospium chloride treatment method A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
23	7781448	Once daily dosage forms of trospium A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
24	7776874	Amido compounds and their use as pharmaceuticals The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The ...
25	7763635	Once daily dosage forms of trospium A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
26	7759359	Method of treating bladder dysfunction with once-a-day trospium salt formulation A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
27	7759383	Small molecule inhibitors of MDM2 and the uses thereof The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth,...
28	7727933	2-ethyl-4,6-dimethyl-phenyl-substituted spirocyclic tetramic acid derivatives The invention relates to novel 2-ethyl-4,6-dimethylphenyl-substituted spirocyclic tetramic acid derivatives of the formula (I) in which A, B and G are as defined above, to a plurality of processes...
29	7723372	Spiroindolinone derivatives There are provided compounds of the general formulas wherein W, X, Y, R1, R2, R3, and R4 are as described herein. The compounds exhibit anticancer activity.
30	7700641	Spiro-oxindole compounds and their uses as therapeutic agents This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R1, R2a, R2b, R2c, R2d, R3a, R3b, R3c, and R3d are as defined herein, as a stereoisomer, enantiomer, tautomer...
31	7659300	Monocyclic anilide spirolactam CGRP receptor antagonists The present invention is directed to compounds of Formula I: I (where A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful in the...
32	7655686	Certain substituted spirocyclic lactams and use thereof as pharmaceuticals The present invention relates to novel 2-(6-oxo-1,7-diaza-spiro[4.4]non-7-yl)-propionamides of the formula wherein R1, R2, R3, R4, R5, R6, m and p are as defined in the specification, to their...
33	7638547	Cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives serving as pesticides The invention relates to novel cis-alkoxy-substituted spirocyclic 1H-pyrrolidine-2,4-dione derivatives of the formula (I) in which A, G, X and Y are as defined in the disclosure, to a plurality of...
34	7638548	Spiroindolinone derivatives There are provided compounds of the general formulas wherein X, Y, R1, R2, R3 and R4 are as described herein. The compounds exhibit anticancer activity.
35	7550499	Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions The present invention provides novel ureas containing N-aryl or N-heteroaryl substituted heterocycles and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention...
36	7538135	Benzenesulfonylamino compounds and pharmaceutical compositions containing these compounds Compounds of the formula provide pharmacological agents which bind to Peroxisome Proliferator-Activated Receptors (PPARs). Accordingly, the compounds of the instant invention are useful for the...
37	7528156	Compounds The invention provides compounds of general formula (D wherein m, n, Q, Z1, Z2, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined in the specification, processes for their preparation,...
38	7524856	Tricyclic spiroderivatives as modulators of chemokine receptor activity The invention provides compounds of formula (I) wherein m, R1, n, R2, q, p, X, Y, R3, R4, t and, R5 are as defined in the specification, processes for their preparation, pharmaceutical compositions...
39	7514466	Purification of progesterone receptor modulators Methods for purifying a compound of formula I are provided, wherein A, B X, Q, and R1 are defined herein. The methods include mixing the compound of formula I and a solvent; adding a base to the...
40	7498338	Compounds The invention provides compounds of formula (I) wherein m, R1, n, R2, q, X, Y, Z, t, R3, R4, R5, R6, R7 and R8 are as defined in the specification, processes for their preparation, pharmaceutical...
41	7476688	Cyclic amidine derivatives A cyclic amidine derivative represented by the formula: [wherein R1, R2 and R3 represent hydrogen, C1-6 alkyl, aryl-C1-6 alkyl, etc.; R4, R5 and R7 represent hydrogen, C1-6 alkyl, etc.; Z...
42	7449475	Tricyclic spiropiperidines or spiropyrrolidines The invention provides compounds of formula (I) wherein m R1, n, R2, q, X, Y, Z, R3, R4, R5, R6, R7, R8, t, and R9 are as defined in the specification, processes for their preparation,...
43	7439263	Pyrrolidine and thiazolidine compounds Compounds of formula (I): wherein: X1 represents an atom or group selected from CR4aR4b, O, S(O)q1 and NR5, wherein R4a, R4b, q1 and R5 are as defined in the description,m1 represents zero or an...
44	7410978	Once daily dosage forms of trospium A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum...
45	7396846	Growth hormone secretagogues This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the...
46	7393858	Tetrahydropyran compounds as tachykinin antagonists The present invention relates to compounds of formula (Ia) wherein A, B, n, m, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are defined herein, and pharmaceutically acceptable salts thereof; the...
47	7390798	Carboxamide spirolactam CGRP receptor antagonists The present invention is directed to compounds of Formula I: I (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful...
48	7304081	Amido compounds and their use as pharmaceuticals The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The ...
49	7288560	Spirocyclic cyclohexane derivatives The present invention relates to spirocyclic cyclohexane compounds, to methods for their production, to pharmaceutical compositions containing these compounds, to methods of treatment using such...
50	7250438	Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a...

Matches 1 - 50 out of 265

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