Matches 601 - 650 out of 786 < 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 >
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5110821 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents  
Compounds of the formula ##STR1## wherein: Y is an alkylene bridge of 3-9 carbon atoms; R' is lower-alkyl or hydroxy-lower-alkyl or 1-5 carbon atoms; R 1 and R 2 are hydrogen, halogen,...
5102903 Treatment of glaucoma and ocular hypertension with pyrazole, pyrrole and triazole angiotensin-II receptor antagonists  
Substituted pyrazole, pyrrole and triazole angiotension-II receptor antagonists and pharmaceutically acceptable salts thereof are useful for treating glaucoma and ocular hypertension.
5093347 3-difluoromethylpyrazolecarboxamide fungicides, compositions and use  
Novel 3-difluoromethyl-1-methyl-N-(substituted-indane-4-yl)pyrazol e-4-carboxamid es useful as fungicides, particularly effective in alleviating infections in diseased plants.
5070098 Substituted pyrazoline derivatives, pesticidal compositions and use  
This invention relates to novel substituted pyrazoline derivatives of the general formula ##STR1## processes for their preparation and their use as pesticides.
5068237 Substituted furans and derivatives thereof acting at muscarinic receptors  
Substituted furans and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and...
5066663 Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors  
Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as...
5066657 Crotonic acid amide derivatives and insectides containing the same  
A crotonic acid amide derivative represented by formula (I): ##STR1## wherein X 1 , X 2 , X 3 , X 4 , and X 5 , which may be the same or different, each represents a hydrogen atom, a halogen atom,...
5064850 Dihydro-3,3-diphenyl-5-(1H-pyrazol-1-ylmethyl-2(3H)-furanone and dihydro-5-((substituted-1H-pyrazol-1-yl)methyl)-3,3-diphenyl-2(3H)-furan one derivatives  
Dihydrofuranone compounds having anticholinergic activity are described. The compounds have the formula: ##STR1## wherein: R 1 is hydrogen or lower alkyl, R 2 is hydrogen or lower alkyl, R...
5064851 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use  
This invention relates to novel 3-(1-substituted-pyrazoyl)-2-oxindole derivatives which are inhibitors of prostaglandin H 2 synthease, 5-lipoxygenase and interleukin-1 biosynthesis. The compounds...
5055475 P-hydroxy phenone derivatives and drugs containing these  
P-hydroxy phenone derivatives of the formula 1 ##STR1## where X is ##STR2## where R 1 =F, Cl, Br or trifluoromethyl or a heteroaryl of the structure ##STR3## with R 2 =C 1 -C 4 - alkyl, Y is...
5051409 2-Aminodecalin derivatives and their use  
2-Aminodecalin derivatives of the formula I ##STR1## where R 1 , R 2 and R 3 are H or methyl, A is H, OH, O-alkylcarbonyl, O-benzoyl or O-CH 3 , R 4 is H, cyclopropyl, alkyl, alkenyl, or...
5051421 Benzo-[b]thiophene derivatives  
Benzo[b]thiophene derivatives of formula ##STR1## their tautomers and salts, in which the index n is 0, 1 or 2, alk is lower alkylene, Ar is phenyl, naphthyl or a monocyclic, five- or six-membered...
5049575 Substituted carboxylic acid, fungicidal compositions and use  
Fungicide contains a substituted pyrazole carboxylic acid of the formula: ##STR1## wherein R 1 is a methyl or trifluoromethyl group, R 2 is halogen atom, R 3 and R 4 are, same or different, a...
5047410 Indolyl derivatives and their use as 5-HT.sub.3, receptor antagonists  
New pharmacologically active amidino and guanidino derivatives which are 5-HT 3 receptor antagonists useful as antiemetic, gastric prokinetic and antimigrainic agents of the following general...
5039694 Substituted-amido compounds and phytopathogenic fungicides containing the same  
Disclosed are substituted-amido derivatives of a general formula (I): ##STR1## in which R 1 represents a group as specifically defined herein; R 2 represents a hydrogen atom, a methyl group, a...
5039692 Phenoxyalkylamine derivatives, and insecticides, acaricides and fungicides  
There are disclosed a phenoxyalkylamine derivative represented by the formula: ##STR1## wherein A 1 represents an alkylene group having 2 to 5 carbon atoms, R 1 and R 2 each represent hydrogen...
5039693 Pyrazole amides and insecticide and miticide containing them as active ingredient  
Novel pyrazole amide and an insecticidal and miticidal composition containing the pyrazole amide as an active ingredient are described. The pyrazole amide according to the present invention shows...
5021413 Analgesic thiomorpholins their preparation, and pharmaceutical compositions containing them  
Analgesic compounds are of the general formula (I): ##STR1## in which, R 1 and R 2 each represents hydrogen or C 1 -C 6 alkyl, or R 1 and R 2 together with the nitrogen atom to which they are...
5017596 Arylpyrazolylcarbinol compounds with analgesic activity  
The present invention relates to novel arylheteroarylcarbinol derivatives with analgesic activity and to their therapeutically acceptable salts. These novel derivatives correspond to the general...
5017573 Indazole-3-carboxylic acid derivatives  
An indazole-3-carboxylic acid derivative represented by the following general formula (I) or its physiologically acceptable acid addition salt or quaternary ammonium salt, ##STR1## wherein Y...
5015644 Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds  
Certain substituted urea, thiourea, carbamate, and thiocarbamate compounds are potent inhibitors of the enzyme acyl-CoA: cholesterol acyltransferase and are thus useful agents for inhibiting the...
5006524 Triphenyl pyrazoline compounds which are useful as insecticides  
Triphenylpyrazoline compounds, including all of their geometric isomers, stereoisomers and agriculturally suitable salts; agricultural compositions containing them; and use of such compounds as...
5006548 Acrylamidobenzoic acid derivatives and their use  
Compounds of the general formula: ##STR1## wherein R 1 is heterocyclic group other than pyridyl and which is unsubstituted or substituted with lower alkyl or lower alkoxycarbonyl, R 2 is...
4994482 Arylpyrazol derivatives as anti-platelet agents, compositions and use  
Compounds of the formula ##STR1## wherein R 1 and R 2 each are independently hydrogen or phenyl, provided that R 1 and R 2 may not both be hydrogen; m is an integer from 3 to 9; n is an...
4990529 Pyrazolone derivatives for treating cerebrovascular diseases  
2-Pyrazoline derivatives of the formula (A): ##STR1## where R 1 is a pyridyl, a pyrazyl or an alkoxyl group; and R 2 is a hydrogen atom, an alkyl, a pyridyl, a furyl, phenyl or a substituted...
4988725 1H-pyrazole-1-(branched)alkanamides as antiarrhythmic agents, compositions and use  
N-[(alkylamino)alkyl]-3,4(or 4,5)-diaryl-1H-pyrazole-1-(branched)alkanamides and pyrazole-1-alkanamines useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl...
4973600 Benzodioxole derivatives, pharmaceutical compositions and use  
Novel benzodioxole derivative of the formula: ##STR1## wherein R 1 is a lower alkyl group, a lower alkoxy-lower alkyl group, phenyl group or pyridyl group, R 2 is hydrogen atom or a halogen atom...
4968691 Heterocyclo-substituted azabicyclo muscannic agonists  
A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## in which X represents a group ##STR2## in which p represents an integer of 2 to 4; r represents an integer of 1 or...
4960781 Fungicidal disazolyl-hydroxyalkyl derivatives  
Fungicidal bisazolyl-hydroxyalkyl derivatives of the formula ##STR1## in which Ar stands for optionally substituted aryl, X stands for a grouping --CH 2 CH 2 --, --OCH 2 --, --SCH 2 -- or...
4956379 Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith  
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. HET 1 --(CH 2 ) n CO 2 R (I)...
4950668 Pyrazole derivative, insecticidal or miticidal composition containing the same as the effective ingredient  
A novel pyrazole derivative and an insecticidal or miticidal composition containing the derivative as the effective ingredient are disclosed. The pyrazole derivative of the present invention has an...
4950678 Substituted N-(heterocyclic-substituted phenyl)-N'-benzylureas  
Novel substituted N-(heterocyclic-substituted phenyl)-N'-benzoyl-ureas, processed for producing these compounds, intermediates therefor, compositions thereof and the use of the compounds for the...
4946845 Naphthalene anti-psoriatic agents  
Psoriasis in mammals is relieved by topically administering naphthalenes of the formula: ##STR1## wherein: R 1 and R 2 are the same and are lower alkoxy or optionally substituted phenoxy, R 3 ...
4943585 N-substituted azoles and insecticide, arachnicide, and nematocide compositions thereof  
4943584 (p-Phenoxyphenoxy)-methyl-five-membered hetaryls  
Novel (p-phenoxyphenoxy)-methyl-five-membered heeroaromatic radicals of the formula ##STR1## where the substituents have the following meanings: R 1 , R 2 , R 3 hydrogen, halogen, C 1 -C 8 ...
4925476 Azole hemiaminal derivatives and their use as nitrification inhibitors  
Nitrification inhibitors contain azole hemiaminal derivatives of the formula ##STR1## where R 1 and R 2 are each hydrogen, alkyl, aryl or halogen, R 3 is alkyl, cycloalkyl, alkoxy, alkenyl,...
4916150 1H-pyrazole-1-alkanamines antiarrhythmic compositions and use  
N-[alkylamino)alkyl]-3,4(or 4,5)-diaryl-1H-pyrazole-1-(branched)alkanamides and pyrazole-1-alkanamines useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl...
4914121 3-Phenyl-1-phenylpyrazole-4 acetic acid compounds which are useful in treating immune diseases  
A pharmaceutical composition comprising as an effective ingredient, a pyrazole compound of the formula ##STR1## wherein each of R 1 and R 2 is phenyl or p-halogenophenyl radical, respectively,...
4898880 N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use  
N-[(heterocycle)alkyl]-3,4 (or 4,5)-diaryl-1H-pyrazole-1-acetamides and pyrazole-1-propanamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of...
4888352 3,4, or 5-aryl-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use  
N-[(disubstituted amino)alkyl]-3,4 or 5-aryl-1H-pyrazole-1-acetamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl ester of pyrazole-1-acetic acid...
4885292 N-heterocyclic alcohol renin inhibitors  
Compounds of the formula ##STR1## are disclosed wherein R 1 is N-heterocyclic moiety. These compounds intervene in the conversion of angiotensin to angiotensin II by inhibiting renin and thus are...
4877441 Fungicidal substituted carboxylic acid derivatives  
A substituted carboxylic acid derivative which is fungicidally active is provided. The compound has the formula: ##STR1## wherein R 1 stands for a methyl or ethyl group, A stands for ##STR2## R 2 ...
4870095 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use  
N-[(disubstituted amino)alkyl]-3,4 (or 4,5)-diaryl-1H-pyrazole-1-acetamides and pyrazole-1-propanamides, useful for treating cardiac arrhythmias in mammals, are prepared by reacting a lower-alkyl...
4868198 3-halogenoalkyl-1-aryl-pyrazole pesticides, compositions and use  
Arthropodically active 3-halogenoalkyl-1-arylpyrzoles of the formula ##STR1## in which R 1 represents halogenoalkyl, R 2 represents cyano, or represents hydroxycarbonyl, or represents...
4863947 N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides and methods of their production  
This invention relates to novel N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamide compounds which are useful as pesticides, compositions containing those compounds, methods of controlling pests...
4853405 Condensed pyrazole derivatives, pharmaceutical compositions and use  
The invention relates to compounds having the general formula (I) ##STR1## and the pharmaceutically acceptable salts thereof, which possess immunomodulating activity and are useful e.g. in the...
4853404 Phenoxyacetic acid derivatives composition and use  
Novel phenoxyacetic acid derivatives of the formula: ##STR1## wherein A is a substituted or unsubstituted 5-pyrazolyl group, R 1 is hydrogen atom or a lower alkyl group, R 2 is hydrogen atom or a...
4851425 Cyclopentapyrazole and tetrahydroindazole compounds and their use as anti-inflammatory and anti-allergic agents  
The present invention provides novel compositions of matter and their therapeutic applications. More particularly, the present invention consists of novel cyclopentapyrazole and tetrahydroindazole...
4851406 Heterocyclic-substituted indoles and pharmaceutical compositions containing them  
The present invention provides indole derivatives of the general formula: ##STR1## wherein R 1 is a hydrogen atom or an alkyl, alkenyl, cycloalkyl, cycloalkenyl, carboxyl, cyano, alkylcarbonyl,...
4845096 Benzofuran derivatives and antiulcerogenic agents containing same  
Benzofuran derivatives of the general formula I ##STR1## where R 1 and R 2 are each hydrogen, alkyl or phenylalkyl, where alkyl in each case is of 1 to 4 carbon atoms, R 3 and R 4 are identical...
Matches 601 - 650 out of 786 < 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 >